• The Bulletin of The Korean Astronomical Society
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• v.43 no.1
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• pp.41.1-41.1
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• 2018

We introduce a current status and future plans of Korea Microlensing Telescope Network (KMTNet) microlensing experiments, which include an observational strategy, pipeline, event-finder, and collaborations with Spitzer. The KMTNet experiments were initiated in 2015. From 2016, KMTNet observes 27 fields including 6 main fields and 21 subfields. In 2017, we have finished the DIA photometry for all 2016 and 2017 data. Thus, it is possible to do a real-time DIA photometry from 2018. The DIA photometric data is used for finding events from the KMTNet event-finder. The KMTNet event-finder has been improved relative to the previous version, which already found 857 events in 4 main fields of 2015. We have applied the improved version to all 2016 data. As a result, we find that 2597 events are found, and out of them, 265 are found in KMTNet-K2C9 overlapping fields. For increasing the detection efficiency of event-finder, we are working on filtering false events out by machine-learning method. In 2018, we plan to measure event detection efficiency of KMTNet by injecting fake events into the pipeline near the image level. Thanks to high-cadence observations, KMTNet found fruitful interesting events including exoplanets and brown dwarfs, which were not found by other groups. Masses of such exoplanets and brown dwarfs are measured from collaborations with Spitzer and other groups. Especially, KMTNet has been closely cooperating with Spitzer from 2015. Thus, KMTNet observes Spitzer fields. As a result, we could measure the microlens parallaxes for many events. Also, the automated KMTNet PySIS pipeline was developed before the 2017 Spitzer season and it played a very important role in selecting the Spitzer target. For the 2018 Spitzer season, we will improve the PySIS pipeline to obtain better photometric results.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.12
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• pp.2021-2030
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• 2020

Objective: Quantitative polymerase chain reaction (qPCR) has been extensively used in the field of mesenchymal stem cell (MSC) research to elucidate their characteristics and clinical potential by normalization of target genes against reference genes (RGs), which are believed to be stably expressed irrespective of various experimental conditions. However, the expression of RGs is also variable depending on the experimental conditions, which may lead to false or contradictory conclusions upon normalization. Due to the current lack of information for a clear list of stable RGs in bovine MSCs, we conducted this study to identify suitable RGs in bovine MSCs. Methods: The cycle threshold values of ten traditionally used RGs (18S ribosomal RNA [18S], beta-2-microglobulin [B2M], H2A histone family, member Z [H2A], peptidylprolyl isomerase A [PPIA], ribosomal protein 4 [RPL4], succinate dehydrogenase complex, subunit A [SDHA], beta actin [ACTB], glyceraldehyde-3-phosphate dehydrogenase [GAPDH], TATA box binding protein [TBP], and hypoxanthine phosphoribosyltrasnfrase1 [HPRT1]) in bovine bone marrow-derived MSCs (bBMMSCs) were validated for their stabilities using three types of RG evaluation algorithms (geNorm, Normfinder, and Bestkeeper). The effect of validated RGs was then verified by normalization of lineage-specific genes (fatty acid binding protein 4 [FABP4] and osteonectin [ON]) expressions during differentiations of bBMMSCs or POU class 5 homeobox 1 (OCT4) expression between bBMMSCs and dermal skins. Results: Based on the results obtained for the three most stable RGs from geNorm (TBP, RPL4, and H2A), Normfinder (TBP, RPL4, and SDHA), and Bestkeeper (TBP, RPL4, and SDHA), it was comprehensively determined that TBP and RPL4 were the most stable RGs in bBMMSCs. However, traditional RGs were suggested to be the least stable (18S) or moderately stable (GAPDH and ACTB) in bBMMSCs. Normalization of FABP4 or ON against TBP, RPL4, and 18S presented significant differences during differentiation of bBMMSCs. However, although significantly low expression of OCT4 was detected in dermal skins compared to that in bBMMSCs when TBP and RPL4 were used in normalization, normalization against 18S exhibited no significance. Conclusion: This study proposes that TBP and RPL4 were suitable as stable RGs for qPCR study in bovine MSCs.

• Food Science of Animal Resources
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• v.25 no.2
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• pp.203-209
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• 2005

Real time-polymerase chain reaction (RT-PCR) is currently considered as the most sensitive method to detect low abundant DNAs in samples. Compared to conventional PCR, real-time PCR has a high reliability because of excluding false-positive results and can allow a simultaneous faster detection and quantification of target DNAs. This study was carried out to identify the Hanwoo (Korean native cattle) beef by genotyping after DNA extraction of commercial beef in 41 restaurants. Since Hanwoo, Holstein and imported cattle meat have different patterns in the MC1R gene associated with the coat colors of cattles (C-type, C/T-type or T-type), we could identify the genotype using real-time PCR The result of real-time PCR assay for beef samples in 41 restaurants which are asserted to sell Hanwoo beef only, showed that 29 of 41 samples were Hanwoo beef gene type (T-type) and 12 of 41 samples were Holstein or imported cattle gene type (C-type or C/T-type). Therefore, the proportion of Han-woo beef was $70.7\%$ and the proportion of Holstein or imported cattle meat was $29.3\%(C/T-type; 12.2\%,\;C-type; 17.1\%)$.

• Korean Journal of Remote Sensing
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• v.34 no.2_2
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• pp.431-437
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• 2018

We analyzed the feasibility of detecting wave gliders moving on the sea surface using SAR images. For the experiment, a model was constructed and placed on the sea using a towing ship before and after the satellite observation time. In the acquisition of KOMPSAT-5 image, high resolution SAR data of spotlight mode was collected considering the small size of wave glider. As a result of the backscattering intensity analysis around the towing ship along with wave glider, several scattering points away from the ship were observed, which are not strong but clearly distinguished from the surrounding clutter values. Considering the distance from the center of the ship, it seems to be a signal by the wave glider. On the other hand, it is confirmed that the wave glider can be detected even at the very low false alarm rate ($10^{-6}$) of the target detection using CFAR. Although the scatter signal by the wave glider could be distinguished from the surrounding ocean clutter in the high resolution SAR image, further research is needed to determine if actual wave gliders are detected in various marine environments.

• Korean journal of communication and information
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• v.40
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• pp.287-320
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• 2007

This study was to look into the press policy and the related activities performed by North Korea in the South during the Korean War and to evaluate them. In order to understand the concrete contents of the activities and their characteristics, the two representative newspapers published in the South by North Korea at that times - the Chosuninmin Bo and the Haebang Ilbo - were reviewed and analyzed. North Korea operated broadcasting and started newspapers just after the possession of Seoul. and also performed various positive press activities - such as the distribution of the newspapers and periodicals of North Korea and U.S.S.R., putting the movies on the screen, and founding the weekly, etc. But the target of all the media were the same. It aimed to support Kim Il-Sung's scheme which intended to carry out the war successfully and to make the South under occupation Communism System by introducing the Northern law and system. The two newspapers, as agent of power, made only such a role to agitate and exaggerate the false things with unrealistic optimism. They intended to ideologically mobilize the South people and to affect on their perspectives and acts. However the media including the two newspapers being operated in the South during the war had not got the faith or the good response from the South people as an audience. Most of South Koreans were tired with their endless and one-sided propaganda, agitation and ideological enlightenment. It could therefore be evaluated that the press activities by North Korea in the South during the Korean War resulted with many limitations in ideologically organizing and mobilizing the South Koreans.

• Journal of the Korea Society of Computer and Information
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• v.21 no.6
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• pp.97-106
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• 2016

This study tries to seek the is the realistic improvements and legislative measures about current medical advertising which was in the Court on 12 May 2015 by presenting and discussion the understanding, problems and its alternative direction of pre-deliberation on the existing law which is the decision on the constitutionality of health care advertising regulated health care advertising General commercial advertising has the right which have to be protected as the terms of the protection of know and freedom of expression and advertiser's there are sure to be in a value to be protected. Medical advertising is also a person in addition to the absolute value that includes both Due to the particularity of medical advertising in terms of life and the right to health Until now, this has been the target of strong regulations are changing the policy of gradual deregulation in our country, including the country. Medical advertising on the current medical law had been to be checked by pre-deliberation of the executive power. However, due to unconstitutional, in the circumstances which a false hype is flooding and increasing, it has been realized that the fair competition of medical community, life and health rights of the people are threatened by in reverse. In this regard, the abolition of the pre-deliberation system of medical advertising can be welcomed by abolition of the old system which is the legal and institutional censorship. Since its abolition, the alternative policy direction is insufficient also it is not clear. Therefore we need to study this. Therefore, in this paper, we try to find general theoretical background and problem of pre-deliberation system of medical advertising. Also, as trying to find feasibility or ambiguity of regulation and issues about medical advertising on medical law, we argued the provision of special measures of the medical advertising for introduction of integrated medical advertising deliberation committee which can ensure the independence and autonomy, strengthening of the monitoring on the internet advertising, legal resolving through amendments, strengthening of penalties, and establish special measures of medical advertising for the medical privatization and demand for the foreign medical tourist, etc. Empirical study about practical regulatory measures of medical advertising which converged the various opinions of consumer groups, government and academia, and medical community, and we expect hope to see the more realistic alternative provision.

• Journal of Korean Society of Transportation
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• v.30 no.6
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• pp.27-36
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• 2012

In Korea, 28,641 cases of traffic accidents were caused by drunk driving in 2010. These statistics accounted for 12.62% of total number of traffic accidents. Moreover, the percentages of deaths and injuries from them were nearly 15% of those from whole traffic accidents. While police has emphasized enforcement efforts in order to reduce drunk driving, culture generous to drunk driving in addition to the absence of an appropriate intervention system for habitual drunk drivers have contributed to the increasing number of the drunk driving accidents in Korea. This study examined specific behavioral changes in drunk driving by comparing drivers' behavior pattern in non-alcoholic condition to those in alcoholic condition, using a psychomotor test and a driving simulator. In the psychomotor test measuring participants' reactions to the target stimulus, it was revealed that participants' correct responses were decreased, false responses were increased, and no responses also were increased after drinking. Furthermore, in the driving simulator performance after drinking, not only driving speed was faster but also the deviation of an accelerator pedal pressure and of the vehicle's lateral position were much increased. These results indicated that alcohol consumption would impair visio-cognitive ability and deteriorate driving safety. Finally, the implications and limitations of our findings and suggestions for the future research were discussed.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.17 no.6
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• pp.25-39
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• 2018

The purpose of this study is to develop an efficient incident detection algorithm by applying machine learning, which is being widely used in the transport sector. As a first step, network of the target site was constructed with micro-simulation model. Secondly, data has been collected under various incident scenarios produced with combination of variables that are expected to affect the incident situation. And, detection results from both McMaster algorithm, a well known incident detection algorithm, and the Naive Bayes algorithm, developed in this study, were compared. As a result of comparison, Naive Bayes algorithm showed less negative effect and better detect rate (DR) than the McMaster algorithm. However, as DR increases, so did false alarm rate (FAR). Also, while McMaster algorithm detected in four cycles, Naive Bayes algorithm determine the situation with just one cycle, which increases DR but also seems to have increased FAR. Consequently it has been identified that the Naive Bayes algorithm has a great potential in traffic incident detection.

• Animal Bioscience
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• v.34 no.11
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• pp.1739-1748
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• 2021

Objective: In recent years, long noncoding RNAs (lncRNAs) have been identified in many species, and some of them have been shown to play important roles in muscle development and myogenesis. However, the differences in lncRNAs between Kazakh cattle and Xinjiang brown cattle remain undefined; therefore, we aimed to confirm whether lncRNAs are differentially expressed in the longissimus dorsi between these two types of cattle and whether differentially expressed lncRNAs regulate muscle differentiation. Methods: We used RNA-seq technology to identify lncRNAs in longissimus muscles from these cattle. The expression of lncRNAs were analyzed using StringTie (1.3.1) in terms of the fragments per kilobase of transcript per million mapped reads values of the encoding genes. The differential expression of the transcripts in the two samples were analyzed using the DESeq R software package. The resulting false discovery rate was controlled by the Benjamini and Hochberg's approach. KOBAS software was utilized to measure the expression of different genes in Kyoto encyclopedia of genes and genomes pathways. We randomly selected eight lncRNA genes and validated them by quantitative reverse transcription polymerase chain reaction (RT-qPCR). Results: We found that 182 lncRNA transcripts, including 102 upregulated and 80 downregulated transcripts, were differentially expressed between Kazakh cattle and Xinjiang brown cattle. The results of RT-qPCR were consistent with the sequencing results. Enrichment analysis and functional annotation of the target genes revealed that the differentially expressed lncRNAs were associated with the mitogen-activated protein kinase, Ras, and phosphatidylinositol 3-kinase (PI3k)/Akt signaling pathways. We also constructed a lncRNA/mRNA coexpression network for the PI3k/Akt signaling pathway. Conclusion: Our study provides insights into cattle muscle-associated lncRNAs and will contribute to a more thorough understanding of the molecular mechanism underlying muscle growth and development in cattle.

• Journal of the Korean Society for Library and Information Science
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• v.56 no.4
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• pp.431-453
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• 2022

Hate is a collective expression of exclusivity toward others and it is fostered and reproduced through false public perception. This study aims to explore the objects and issues of hate discussed in our society using text mining techniques. To this end, we collected 17,867 news data published from 1990 to 2020 and constructed a co-word network and cluster analysis. In order to derive an explicit co-word network highly related to hate, we carried out sentence split and extracted a total of 52,520 sentences containing the words 'hate', 'prejudice' and 'discrimination' in the preprocessing phase. As a result of analyzing the frequency of words in the collected news data, the subjects that appeared most frequently in relation to hate in our society were women, race, and sexual minorities, and the related issues were related laws and crimes. As a result of cluster analysis based on the co-word network, we found a total of six hate-related clusters. The largest cluster was 'genderphobic', accounting for 41.4% of the total, followed by 'sexual minority hatred' at 28.7%, 'racial hatred' at 15.1%, 'selective hatred' at 8.5%, 'political hatred' accounted for 5.7% and 'environmental hatred' accounted for 0.3%. In the discussion, we comprehensively extracted all specific hate target names from the collected news data, which were not specifically revealed as a result of the cluster analysis.