• Title/Summary/Keyword: False negative rate

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Estimation in Group Testing when a Dilution Effect exists

  • Kwon, Se-Hyug
    • Communications for Statistical Applications and Methods
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    • v.13 no.3
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    • pp.787-794
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    • 2006
  • In group testing, the test unit consists of a group of individuals and each group is tested to classify units from a population as infected or non-infected or estimate the infection rate. If the test group is infected, one or more individuals in the group are presumed to be infected. It is assumed in group testing that classification of group as positive or negative is without error. But, the possibility of false negatives as a result of dilution effects happens often in practice, specially in many clinical researches. In this paper, dilution effect models in group testing are discussed and estimation methods of infection rate are proposed when a dilution effect exists.

Assessment of Primary Spontaneous Pneumothorax Using Chest Computerized Axial Tomography (원발성 자연기흉에서 흉부 컴퓨터 단층촬영의 진단적 의의)

  • Kim, Mun-Hwan;Lee, Cheol-Ju;Kim, Se-Hwan
    • Journal of Chest Surgery
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    • v.26 no.3
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    • pp.209-213
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    • 1993
  • The pathogenesis of the primary spontaneous pneumothorax is the rupture of subpleural bleb or bullae and subsequent sudden collapse of the affected lung. Mostly, the bullae or blebs are present bilaterally, but detecting the number, size, and location of the causating foci by plain chest film is quite difficult . We have performed chest CT scans for detecting the bullous lesions in 33 cases of primary spontaneous pneumothorax, and compared the results with surgical findings.1. Seventy-four blebs were identified in the chest CT scan, and 100 blebs or bullae were detected surgically [ Sensitivity was 0.74 ].2. Diagnosis rate was 80% [40/50] at right upper lobe, 75.7% [28/37] at left upper lobe, 55.6% at right lower lobe, and 25.0% at left lower lobe, respectively.3. Blebs or bullae smaller than 1 cm of its diameter were detected by 57.1% [24/42] of sensitivity, and in the cases of size larger than 1 cm, it revealed 86.2% [50/58] of sensitivity respectively.4. Of the 45 cases, 7 cases were false negative [15.6%], most of these were ruptured or small size [< 0.5 cm]. 5. One case was false positive, which was irregular adhesion at the apex of the lung.6. We could detect blebs or bullae with preoperative CT scans in 84.4% [38/45] of total patients. In conclusion, chest CT scan is a very advantageous diagnostic tool for proper management and preventing recurrence of primary spontaneous pneumothorax patient.

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An Hybrid Probe Detection Model using FCM and Self-Adaptive Module (자가적응모듈과 퍼지인식도가 적용된 하이브리드 침입시도탐지모델)

  • Lee, Seyul
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.13 no.3
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    • pp.19-25
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    • 2017
  • Nowadays, networked computer systems play an increasingly important role in our society and its economy. They have become the targets of a wide array of malicious attacks that invariably turn into actual intrusions. This is the reason computer security has become an essential concern for network administrators. Recently, a number of Detection/Prevention System schemes have been proposed based on various technologies. However, the techniques, which have been applied in many systems, are useful only for the existing patterns of intrusion. Therefore, probe detection has become a major security protection technology to detection potential attacks. Probe detection needs to take into account a variety of factors ant the relationship between the various factors to reduce false negative & positive error. It is necessary to develop new technology of probe detection that can find new pattern of probe. In this paper, we propose an hybrid probe detection using Fuzzy Cognitive Map(FCM) and Self Adaptive Module(SAM) in dynamic environment such as Cloud and IoT. Also, in order to verify the proposed method, experiments about measuring detection rate in dynamic environments and possibility of countermeasure against intrusion were performed. From experimental results, decrease of false detection and the possibilities of countermeasures against intrusions were confirmed.

Discriminant Metric Learning Approach for Face Verification

  • Chen, Ju-Chin;Wu, Pei-Hsun;Lien, Jenn-Jier James
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.9 no.2
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    • pp.742-762
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    • 2015
  • In this study, we propose a distance metric learning approach called discriminant metric learning (DML) for face verification, which addresses a binary-class problem for classifying whether or not two input images are of the same subject. The critical issue for solving this problem is determining the method to be used for measuring the distance between two images. Among various methods, the large margin nearest neighbor (LMNN) method is a state-of-the-art algorithm. However, to compensate the LMNN's entangled data distribution due to high levels of appearance variations in unconstrained environments, DML's goal is to penalize violations of the negative pair distance relationship, i.e., the images with different labels, while being integrated with LMNN to model the distance relation between positive pairs, i.e., the images with the same label. The likelihoods of the input images, estimated using DML and LMNN metrics, are then weighted and combined for further analysis. Additionally, rather than using the k-nearest neighbor (k-NN) classification mechanism, we propose a verification mechanism that measures the correlation of the class label distribution of neighbors to reduce the false negative rate of positive pairs. From the experimental results, we see that DML can modify the relation of negative pairs in the original LMNN space and compensate for LMNN's performance on faces with large variances, such as pose and expression.

Preoperative Diagnostic Value of Fine Needle Aspiration(FNA) Cytology of Palpable Thyroid Nodules (갑상선 결절에 대한 세침흡입 세포검사의 수술전 진단적 가치)

  • Jeon Byeong-Min;Lee Byeong-Wook;Kim Sang-Hyo;Paik Nak-Whan
    • Korean Journal of Head & Neck Oncology
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    • v.10 no.2
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    • pp.192-199
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    • 1994
  • Since 1950s, fine needle aspiration(FNA) cytology has become increasingly popular and numerous reports have demonstrate its accuracy, safety and cost-effectiveness. To evaluate the role of diagnostic FNA cytology in the thyroid nodule, authors compared preoperative cytologic findings with postoperative histologic diagnosis in two hundred two thyroid nodules underwent surgical resection at Department of Surgery, Pusan Paik Hospital. from July 1990 to December 1993. FNA and thyroidectomy was performed primarily by one Head and Neck surgeon and specimen was interpreted by several pathologists. One hundred seventy two FNAs(85%) were interpreted as positive for benign lesion or carcinoma and thirty(15%, cystic in 25, non-cystic lesion in 5 cases) were unsatisfactory specimens for interpretation. The preoperative cytologic diagnosis of 172 cases revealed 'benign' in 112. 'suspicious cancer' in 10 and 'cancer' in 50 cases. Postoperative pathologic diagnosis showed 'nodular goiter' in 64. 'benign tumor' in 43, 'thyroiditis' in 4 and 'cancer' in 61 cases. The value of preoperative FNA diagnosis for thyroid cancer yielded a sensitivity of 85.2%, a specificity of 92.7%, false negative rate 5.2%, false positive rate 4.5% and positive predictive value and overall accuracy were 86.6% and 90.1% respectively. Preoperative rate of malignancy could be increased up to 35.5% by using FNA.

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A Study of Diagnostic Value on Fine Needle Aspiration Cytology of the Breast Masses (유방종괴의 세침흡인세포학의 진단적 가치에 관한 연구)

  • Kim, Dong-Won;Lee, Dong-Wha
    • The Korean Journal of Cytopathology
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    • v.4 no.1
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    • pp.1-8
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    • 1993
  • This study was performed in order to evaluate the accuracy and the usefulness of the fine needle aspiration cytology (FNAC) on the breast lesions, to compare the FNAC findings between fibroadenoma and fibrocystic disease, and to determine the accuracy of cytologic Black's nuclear grading. The subjects in this study were 110 cases of FNAC, later confirmed by biopsy, between January 1988 and December 1991. The results are as follows ; 1 Comparison between the results of the FNAC and the histologic findings revealed that FNAC had a sensitivity of 96.6%, a specificity of 100%, a false negative rate of 3.4% a false positive rate of 0.0%, and an overall diagnostic accuracy of 98.2%. 2 Semi-quantitative evaluation of epithelial celluarity, stroma, and naked nuclei in the smears of aspirate showed high celluarity in 56.7% of the aspirates from fibroadenoma and in 0% of those from fibrocystic disease. Abundant stroma was found in 46.7% of the fibroadenoma and none of fibrocystic disease. Numerous naked nuclei were found in 60% of the fibroadenoma and 4.5% of the fibrocystic disease. The overall diagnostic accuracy was 98% 3. In order to determine the accuracy of Black's nuclear grading of FNAC on breast carcinoma, we retrospectively studied 38 cases of ductal carcinomas diagnosed by FNAC with subsequent histologic confirmation. The concordance rate with histology was 94.7%. These results suggest that FNAC of breast is a diagnostically accurate method, and provide for the preoperative differential diagnosis between fibroadenoma and fibrocystic disease. Our results also suggest that the evaluation of nuclear grading of FNAC can predict clinical outcome and decide the way of management of breast cancer.

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Image Forensic Decision Algorithm using Edge Energy Information of Forgery Image (위·변조 영상의 에지 에너지 정보를 이용한 영상 포렌식 판정 알고리즘)

  • Rhee, Kang Hyeon
    • Journal of the Institute of Electronics and Information Engineers
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    • v.51 no.3
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    • pp.75-81
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    • 2014
  • In a distribution of the digital image, there is a serious problem that is distributed an illegal forgery image by pirates. For the problem solution, this paper proposes an image forensic decision algorithm using an edge energy information of forgery image. The algorithm uses SA (Streaking Artifacts) and SPAM (Subtractive Pixel Adjacency Matrix) to extract the edge energy informations of original image according to JPEG compression rate(QF=90, 70, 50 and 30) and the query image. And then it decides the forge whether or not by comparing the edge informations between the original and query image each other. According to each threshold in TCJCR (Threshold by Combination of JPEG Compression Ratios), the matching of the edge informations of original and query image is excused. Through the matching experiments, TP (True Positive) and FN (False Negative) is 87.2% and 13.8% respectively. Thus, the minimum average decision error is 0.1349. Also, it is confirmed that the performed class evaluation of the proposed algorithm is 'Excellent(A)' because of the AUROC (Area Under Receiver Operating Characteristic) curve is 0.9388 by sensitivity and 1-specificity.

The Effect of Franchisors' Gapjil on Economic Satisfaction, Social Satisfaction, and Recontract Intention

  • HUR, Soon-Beom;LEE, Yong-Ki
    • The Korean Journal of Franchise Management
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    • v.12 no.2
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    • pp.35-49
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    • 2021
  • Purpose: The major objective of this study is to develop a model for the impact of franchisors' Gapjil (verbal·nonverbal Gapjil, abusing bargaining position, refusing transaction, false or exaggerated information, restrictive practices, unfair damage compensation) on franchisee's recontract intention. We also examine the mediating role of economic satisfaction and social satisfaction in the relationship between franchisors' Gapjil and franchisee's contract intention. Research design, data, and methodology: Data were collected from franchisee owners located nationwide in Korea. Out of 256 questionaires distributed, a total of 256 questionnaires were returned. After excluding 10 invalid respondent questionnaires, we coded and analyzed 246 valid questionnaires (effective response rate of 96.09%) using frequency, confirmatory factor analysis, correlations analysis, and structural equation modeling with SPSS 22.O and SmartPLS 3.0. Results: The findings of this study are summarized as follows: First, among the Gapjil of the franchisors, restrictive practices and unfair damage compensation had negative effects on economic and social satisfaction, but verbal and nonverbal Gapjil for economic and social satisfaction was not significant. Second, abusing bargaining positions and false or exaggerated information had negative effects on social satisfaction, but for economic satisfaction, found to be insignificant. Third, economic and social satisfaction had positive effects on the franchisee's recontract intention to the franchisor. Conclusion: The following implications of this study are as follows. First, the construct of Gapjil that occurs between the franchisors and the franchisees was first presented, and the franchisors' Gapjil is divided into interpersonal Gapjil and structural Gapjil. Second, the Gapjil of the franchisors can be an important predictor variable in maintaining and developing a long-term relationship between the franchisors and the franchisees. Third, solving conflict due to the Gapjil problem between franchisors and franchisees can be an important factor for franchisors and franchisees to co-survive and thrive in Korean franchise system. Fourth, this study suggest that managing the Gapjil of the franchisors was a important antecedent factor in maintaining long-term relationship between the franchisors and the franchisees. Therefore, this study will help franchisors formulate effective symbiotic marketing strategies to satisfy relationships with franchisees and consequently enhance long-term orientation.

A Comparison of Conventional Cytology and ThinPrep Cytology of Bronchial Washing Fluid in the Diagnosis of Lung Cancer (폐암의 진단 검사 중 기관지 세척액에서 ThinPrep검사법과 기존의 세포검사법의 유용성에 대한 비교)

  • Kim, Sang-Hoon;Kim, Eun Kyung;Shi, Kyeh-Dong;Kim, Jung-Hyun;Kim, Kyung Soo;Yoo, Jeong-Hwan;Kim, Joo-Young;Kim, Gwang-Il;Ahn, Hee-Jung;Lee, Ji-Hyun
    • Tuberculosis and Respiratory Diseases
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    • v.62 no.6
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    • pp.523-530
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    • 2007
  • Background: A ThinPrep$^{(R)}$ Processor was developed to overcome the limitations of conventional cytology and is widely used to diagnose various cancers. This study compared the diagnostic efficacy of conventional cytology for lung cancer with that of the ThinPrep$^{(R)}$ cytology using the bronchial washing fluid. Methods: The bronchial washing fluid of 790 patients from Jan. 2002 to Dec. 2006, who were suspected of gaving a lung malignancy, was evaluated. Both ThinPrep$^{(R)}$ and conventional cytology were performed for all specimens. Result: Four hundred forty-six men and 344 women were enrolled in this study, and 197 of them were diagnosed with cancer from either a bronchoscopic biopsy or a percutaneous needle aspiration biopsy. ThinPrep$^{(R)}$ cytology showed a sensitivity, specificity, positive predictive value, negative predictive value and false negative error rate of 71.1%, 98.0%, 92.1%, 91.1%, 8.9%, respectively. The conventional cytology showed sensitivity, specificity, positive predictive value, nagative predictive value and false negative error rate of 57.9%, 98.0%, 90.5%, 87.5%, 12.5%, respectively. For central lesions, the sensitivity of conventional cytology and ThinPrep$^{(R)}$ were 70.1% and 82.8%, respectively. Conclusion: ThinPrep$^{(R)}$ cytology showed a higher sensitivity and lower false negative error rate than conventional cytology. This result was unaffected by the histological classification of lung cancer. Therefore, ThinPrep$^{(R)}$ cytology appears to be a useful method for increasing the detection rate of lung cancer in bronchial washing cytology test.

Diagnostic Value of the Intradermal Test for the Infection with Clonorchis sinensis (간흡충증 진단을 위한 피내반응검사의 의의)

  • Kim, Jong-Ho;Yun, Bong-Yung;Lee, Heun-Ju;Lee, Hyun-Woo
    • Journal of Yeungnam Medical Science
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    • v.5 no.2
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    • pp.47-52
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    • 1988
  • The intradermal(ID) test has been widely used in Korea and several reports about the results of the ID test are known. We examined the egg of Clonorchis sinensis(C. s.) by ID test in 443, stool's egg-counting technique in 79 and direct smear(cellophane thick smear technique) in 1304 subjects. The results are as follows.: 1. The positive rate of C. s. was 3.8% out of 1304 persons. 2. The sensitivity of ID test was 82.1% out of 39 persons and, the specificity was 64.6% out of 404 persons. 3. The false positive of ID test 35.4% out of 404 persons and, the false negative was 17.9% out of 39 persons. Intradermal test is a rapid, sensitive and useful supplementary diagnostic tool for the detection of Clonorchiasis infection and must be used as screening test with direct smear of stool but cross reaction with other helminth infections and moderate false reaction are the main disadvantages in its practical application.

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