• 제목/요약/키워드: False Positives

검색결과 173건 처리시간 0.025초

False-Positive Mycobacterium tuberculosis Detection: Ways to Prevent Cross-Contamination

  • Asgharzadeh, Mohammad;Ozma, Mahdi Asghari;Rashedi, Jalil;Poor, Behroz Mahdavi;Agharzadeh, Vahid;Vegari, Ali;Shokouhi, Behrooz;Ganbarov, Khudaverdi;Ghalehlou, Nima Najafi;Leylabadlo, Hamed Ebrahmzadeh;Kafil, Hossein Samadi
    • Tuberculosis and Respiratory Diseases
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    • 제83권3호
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    • pp.211-217
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    • 2020
  • The gold standard method for diagnosis of tuberculosis is the isolation of Mycobacterium tuberculosis through culture, but there is a probability of cross-contamination in simultaneous cultures of samples causing false-positives. This can result in delayed treatment of the underlying disease and drug side effects. In this paper, we reviewed studies on false-positive cultures of M. tuberculosis. Rate of occurrence, effective factors, and extent of false-positives were analyzed. Ways to identify and reduce the false-positives and management of them are critical for all laboratories. In most cases, false-positive is occurring in cases with only one positive culture but negative direct smear. The three most crucial factors in this regard are inappropriate technician function, contamination of reagents, and aerosol production. Thus, to reduce false-positives, good laboratory practice, as well as use of whole-genome sequencing or genotyping of all positive culture samples with a robust, extra pure method and rapid response, are essential for minimizing the rate of false-positives. Indeed, molecular approaches and epidemiological surveillance can provide a valuable tool besides culture to identify possible false positives.

On Reducing False Positives of a Bloom Filter in Trie-Based Algorithms

  • Mun, Ju Hyoung;Lim, Hyesook
    • IEIE Transactions on Smart Processing and Computing
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    • 제4권3호
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    • pp.163-168
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    • 2015
  • Many IP address lookup approaches employ Bloom filters to obtain a high-speed search performance. Especially, it has been recently studied that the search performance of trie-based algorithms can be significantly improved by adding Bloom filters. In such algorithms, the number of trie accesses can be greatly reduced because Bloom filters can determine whether a node exists in a trie without actually accessing the trie. Bloom filters do not have false negatives but have false positives. False positives can lead to unnecessary trie accesses. The false positive rate must thus be reduced to enhance the performance of lookup algorithms applying Bloom filters. One important characteristic of trie-based algorithms is that all the ancestors of a node are also stored. The proposed algorithm utilizes this characteristic in reducing the false positive rate of a Bloom filter without increasing the size of the memory for the Bloom filter. When a Bloom filter produces a positive result for a node of a trie, we propose to check whether the ancestors of the node are also positives. Because Bloom filters have no false negatives, the negatives of any of the ancestors mean that the positive of the node is false. In other words, we propose to use more Bloom filter queries to reduce the false positive rate of a Bloom filter in trie-based algorithms. Simulation results show that querying one ancestor of a node can reduce the false positive rate by up to 67% with exactly the same architecture and the same memory requirement. The proposed approach can be applied to other trie-based algorithms employing Bloom filters.

An Automatic Portscan Detection System with Adaptive Threshold Setting

  • Kim, Sang-Kon;Lee, Seung-Ho;Seo, Seung-Woo
    • Journal of Communications and Networks
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    • 제12권1호
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    • pp.74-85
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    • 2010
  • For the purpose of compromising hosts, attackers including infected hosts initially perform a portscan using IP addresses in order to find vulnerable hosts. Considerable research related to portscan detection has been done and many algorithms have been proposed and implemented in the network intrusion detection system (NIDS). In order to distinguish portscanners from remote hosts, most portscan detection algorithms use a fixed threshold that is manually managed by the network manager. Because the threshold is a constant, even though the network environment or the characteristics of traffic can change, many false positives and false negatives are generated by NIDS. This reduces the efficiency of NIDS and imposes a high processing burden on a network management system (NMS). In this paper, in order to address this problem, we propose an automatic portscan detection system using an fast increase slow decrease (FISD) scheme, that will automatically and adaptively set the threshold based on statistical data for traffic during prior time periods. In particular, we focus on reducing false positives rather than false negatives, while the threshold is adaptively set within a range between minimum and maximum values. We also propose a new portscan detection algorithm, rate of increase in the number of failed connection request (RINF), which is much more suitable for our system and shows better performance than other existing algorithms. In terms of the implementation, we compare our scheme with other two simple threshold estimation methods for an adaptive threshold setting scheme. Also, we compare our detection algorithm with other three existing approaches for portscan detection using a real traffic trace. In summary, we show that FISD results in less false positives than other schemes and RINF can fast and accurately detect portscanners. We also show that the proposed system, including our scheme and algorithm, provides good performance in terms of the rate of false positives.

Improvement of Decarboxylating Agar Medium for Screening Biogenic Amine-Producting Bacteria in Kimchi

  • Mah, Jae-Hyung;Shin, Soon-Young;Lee, Heung-Shick;Cho, Hong-Yon;Hwang, Han-Joon
    • Journal of Microbiology and Biotechnology
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    • 제11권3호
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    • pp.491-496
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    • 2001
  • A modification of decarboxylating agar medium as described by niven was performed to improve the detection method of biogenic amine-producing bacteria and to eliminate the false-positive. A total of 120 bacterial strains isolated from kimchi were used to evaluate different dicarboxylating agar media and for screening biogenic amines. Potential false-positives ranged from approximately 66 to 79% of the strains tested in the already well-known media. In our improved medium, none of the 120 strains showed the potential false-positives. There was a good agreement (81.7%-87.5%) between the results obtained by the improved medium and by HPLC analysis. Consequently, this medium was greatly improved in screening biogenic amine-producing bacteria and discarding false-positives. Of the 120 kimchi isolates, 14.2, 18.3, 37.5, and 0.8% were found by HPLC to be the producers of histamine, tyramine, putrescine (as a form of spermine), and cadaverine, respectively. The proportion of biogenic amine producer during kimchi fermentation increased to a maximum at an immature period and decreased thereafter.

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Real-time Smoke Detection Research with False Positive Reduction using Spatial and Temporal Features based on Faster R-CNN

  • Lee, Sang-Hoon;Lee, Yeung-Hak
    • 전기전자학회논문지
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    • 제24권4호
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    • pp.1148-1155
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    • 2020
  • Fire must be extinguished as quickly as possible because they cause a lot of economic loss and take away precious human lives. Especially, the detection of smoke, which tends to be found first in fire, is of great importance. Smoke detection based on image has many difficulties in algorithm research due to the irregular shape of smoke. In this study, we introduce a new real-time smoke detection algorithm that reduces the detection of false positives generated by irregular smoke shape based on faster r-cnn of factory-installed surveillance cameras. First, we compute the global frame similarity and mean squared error (MSE) to detect the movement of smoke from the input surveillance camera. Second, we use deep learning algorithm (Faster r-cnn) to extract deferred candidate regions. Third, the extracted candidate areas for acting are finally determined using space and temporal features as smoke area. In this study, we proposed a new algorithm using the space and temporal features of global and local frames, which are well-proposed object information, to reduce false positives based on deep learning techniques. The experimental results confirmed that the proposed algorithm has excellent performance by reducing false positives of about 99.0% while maintaining smoke detection performance.

Approaches for Improving Bloom Filter-Based Set Membership Query

  • Lee, HyunYong;Lee, Byung-Tak
    • Journal of Information Processing Systems
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    • 제15권3호
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    • pp.550-569
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    • 2019
  • We propose approaches for improving Bloom filter in terms of false positive probability and membership query speed. To reduce the false positive probability, we propose special type of additional Bloom filters that are used to handle false positives caused by the original Bloom filter. Implementing the proposed approach for a routing table lookup, we show that our approach reduces the routing table lookup time by up to 28% compared to the original Bloom filter by handling most false positives within the fast memory. We also introduce an approach for improving the membership query speed. Taking the hash table-like approach while storing only values, the proposed approach shows much faster membership query speed than the original Bloom filter (e.g., 34 times faster with 10 subsets). Even compared to a hash table, our approach reduces the routing table lookup time by up to 58%.

보행자 상반신 검출에서의 컬러 세그먼테이션 활용 (Exploiting Color Segmentation in Pedestrian Upper-body Detection)

  • 박래정
    • 전자공학회논문지
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    • 제51권11호
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    • pp.181-186
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    • 2014
  • 본 논문에서는 보행자 상반신 검출기의 성능을 향상하기 위한 세그먼테이션에 기반한 특징 추출 방법을 제안한다. 상반신의 부분별 색상 분포를 활용한 멀티 파트 컬러 세그먼테이션을 사용하여 국소 특징이 갖는 한계로 인해 발생하는 오검출의 감소에 효과적인 "전역적" 윤곽 특징을 추출한다. 컬러 공간과 히스토그램 분해도에 따른 성능을 분석하였으며, 자체 구축한 보행자 상반신 영상을 사용한 실험을 통해서 제안한 방법으로 추출한 특징이 국소 특징 기반 검출기의 오검출 감소에 효과적임을 확인하였다.

무선 센서 네트워크에서 클러스터 기반의 Top-k 질의 처리 (A Cluster-Based Top-k Query Processing Algorithm in Wireless Sensor Networks)

  • 여명호;성동욱;유재수
    • 한국정보과학회논문지:데이타베이스
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    • 제36권4호
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    • pp.306-313
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    • 2009
  • 센서 네트워크 응용 분야에서 Top-k 질의는 가장 높은 혹은 가장 낮은 k개의 센서에 대한 유용한 정보를 제공한다. Top-k 질의 처리 시 에너지 소모를 줄이기 위한 많은 연구들이 진행되었다. FILA의 경우, 필터를 이용하여 불필요한 결과의 갱신을 제거하였으며, PRIM의 경우, 센싱된 데이타의 우선 순위를 부여하여 센서 데이타의 전송을 최소화하는 방법을 제안한다. 하지만, 같은 데이타 범위(프레임)에 속한 모든 데이타를 수집하기 때문에 데이타의 집중이 발생하면 많은 False Positive 데이타를 전송하는 문제가 발생한다. 본 논문에서는 Top-k 결과의 False Positive 데이타를 효과적으로 제거하기 위한 클러스터 기반의 새로운 Top-k 질의 처리 기법을 제안한다. 질의 처리 과정은 클러스터 레벨과 트리 레벨로 나누어지며, 각 레벨의 네트워크 토폴로지의 특성을 활용하여 False Positive 데이타를 효과적으로 필터링 한다. 성능 평가 결과, 기존 Top-k 질의 처리 기법에 비해 False Positive 데이타의 수가 70% 감소하고, 네트워크 수명이 약 105% 연장된다.

송.수신 이메일의 학습을 통해 긍정 오류를 줄이는 개선된 베이지안 필터링 기법 (Improved Bayesian Filtering mechanism to reduce the false positives by training both Sending and Receiving e-mails)

  • 김두환;유종덕;정수환
    • 정보보호학회논문지
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    • 제18권2호
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    • pp.129-137
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    • 2008
  • 본 논문에서는 기존의 베이지안 필터링 방식에서 발생하는 긍정 오류를 줄이기 위한 개선된 베이지안 필터링 기법을 제안한다. 기존의 베이지안 필터링 방식에서는 이메일 서버에서 학습한 DB를 일괄적으로 개별 사용자들에게 적용한다. 또한 수신 이메일 위주의 학습 방식은 양질의 정상 DB를 학습하는데 어려움을 준다. 이러한 문제로 인해 기존의 베이지안 필터링 기법에서는 정상 이메일을 스팸 이메일로 판단하는 긍정 오류가 발생한다. 제안 기법에서는 사용자의 송신 이메일을 양질의 정상 DB 정보로 판단하여 베이지안 정상 DB에 자동으로 학습한다. 뿐만 아니라 개별 사용자에게 독립적인 베이지안 DB를 제공하여 사용자 개개인의 이메일 송 수신 특성을 고려한 필터링 서비스를 제공한다. 제안 기법은 기존의 베이지안 필터링 기법보다 필터링의 정확성에서 평균 3.13% 향상된 결과를 보인다.

On-off controllable RNA hybrid expression vector for yeast three-hybrid system

  • Bak, Geunu;Hwang, Se-Won;Ko, Ye-Rim;Lee, Jung-Min;Kim, Young-Mi;Kim, Kyung-Hwan;Hong, Soon-Kang;Lee, Young-Hoon
    • BMB Reports
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    • 제43권2호
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    • pp.110-114
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    • 2010
  • The yeast three-hybrid system (Y3H), a powerful method for identifying RNA-binding proteins, still suffers from many false positives, due mostly to RNA-independent interactions. In this study, we attempted to efficiently identify false positives by introducing a tetracycline operator (tetO) motif into the RPR1 promoter of an RNA hybrid expression vector. We successfully developed a tight tetracycline-regulatable RPR1 promoter variant containing a single tetO motif between the transcription start site and the A-box sequence of the RPR1 promoter. Expression from this tetracycline-regulatable RPR1 promoter in the presence of tetracycline-response transcription activator (tTA) was positively controlled by doxycycline (Dox), a derivative of tetracycline. This on-off control runs opposite to the general knowledge that Dox negatively regulates tTA. This positively controlled RPR1 promoter system can therefore efficiently eliminate RNA-independent false positives commonly observed in the Y3H system by directly monitoring RNA hybrid expression.