• Clinical and Experimental Reproductive Medicine
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• 제30권2호
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• pp.141-150
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• 2003

Objective: To evaluate whether diagnostic laparoscopy before transcervical fallopian tube catheterization (TFTC) would improve tubal recanalization rate and pregnancy rate in patients with bilateral proximal tubal blockage in hysterosalpingogram (HSG). Methods: The retrospective study was performed in those underwent TFTC from January 1998 to December 2001. A total of 50 patients with bilateral proximal tubal blockage in HSG were subjected to TFTC sequentially using repeated HSG (rHSG), selective salpingography (SS) followed by tubal catheterization (TFTC). Each procedure was terminated once patency had been achieved without proceding to the next technique. In Group A patients (n=35, 64 tubes), diagnostic laparoscopy was performed before TFTC was taken to exclude the tube combined with peritubal adhesion or distal tubal pathology. In Group B, patients (n=15, 26 tubes) were performed TFTC without diagnostic laparoscopy. Results: There were significant difference in clinical pregnancy rate (45.7% vs 15.4%, p=0.034) but no differences were found in recanalization rate (75.0% vs 73.1%) and complication rate (8.6% vs 13.3%). Although there is no signficant difference, more tubes were canalized by SS, which means tubal obstruction rather than occlusion, in Group A (25.0% vs 5.3%, p=0.069). Conclusion: Diagnostic laparoscopy would be effective in the selection of tube for the relatively inexpensive and less invasive TFTC or patients in need of assisted reproductive technologies. With the tubes without combined peritubal adhesion or distal tubal pathology, pregnancy rate was significantly increased.

• Clinical and Experimental Reproductive Medicine
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• 제30권3호
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• pp.249-254
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• 2003

Ectopic pregnancy is a common medical problem that is difficult to diagnose and potentially may lead to significant mortality or morbidity. The incidence of ectopic pregnancy is definitely increasing ue to the rise in pelvic inflammatory disease (PID), pelvic surgery, intrauterine device (IUD), and assisted reproductive technologies, such as in vitro fertilization and embryo transfer (IVF-ET). Combined ectopic gestations are much rare and their true incidence is unknown. Multiple ectopic gestations may occur in a variety of locations. The majority involve one or both fallopian tubes. We report a case of combined tubal and cervical pregnancies, and discuss their management.

• Asian-Australasian Journal of Animal Sciences
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• 제4권1호
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• pp.73-78
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• 1991

Sixty-one 5-11 month-old California, Chinchilla and New Zealand White rabbit were employed in this investigation. Thirty-three does were superovulated by injecting FSH/HCG subcutaneously or intravenously and then sacrificed at different hours after mating. The ova were collected from the fallopian tubes with Ham's F-10 medium supplemented with 0.4% bovine serum albumin (BSA) and 1% pregnant rabbit serum (PRS). Embryos were examined under an inverted DIC microscopy for observing the stage of development. We have found that the fertilized ova formed pronuclei at 19 - 20 hr postcoitus. Approximately at 26, 64 - 78 and 84 - 88 hr after mating, the fertilized ova cleaved further to 2-cell, morulae and blastocyst stage respectively. Another 28 does were allocated to the gene transfer study. Fourteen of the 28 does were sacrificed at 19 - 20 hr to donate the pronuclear stage ova for gene injection. The other 14 does were induced to pseudopreganacy by injection of 100 IU HCG intravenous as recipients. Four hundreds and seventeen ova were injected totally and 212 gene injected zygotes were transferred into the recipient oviducts. Five recipients became pregnant and 10 fetuses were obtained. Eight of the 10 fetuses were analysed for gene incorporation, but none of them were transgenic.

• 대한한방부인과학회지
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• 제15권4호
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• pp.218-227
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• 2002

Pelvic Inflammatory Disease(PID) is a spectrum of inflammatory disorders of the female genital tract involving at least the endrometrium and may include the fallopian tubes, ovaries, and pelvic cavity. Women with PID acutely experience pain and are at risk for sepsis; however, the long-term complications such as chronic pelvic pain, organic changes like chronic salpingitis, adhesions, etc., and the significant increases in ectopic pregnancy and infertility are more important and hard to control. This study is about one patient who has chronic PID with inflammatory pelvic mass. The patient was treated with retention enema therapy which use herbs effective for reducing inflammation, resolution abdominal mass, promoting blood circulation. Also, treated with herbal medication of Danchisoyosan(丹梔逍遙散) and Moxibution at Zhongwan(中脘), Guanyuan(關元). After total treatment for three months, the patient's symptoms are improved and the size of inflammatory pelvic mass is reduced. This results indicates that the combination treatment, especially the retention enema therapy is effective on reducing symptoms of PID and the size of secondary inflammatory organic changes.

• 대한영상의학회지
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• 제79권6호
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• pp.337-339
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• 2018

난소위체 낭종은 대부분 양성 단순 낭종의 형태로 나타나며 자궁부속기 종괴의 10~20%를 차지한다. 경계성 혹은 악성 난소위체 종양은 드물며, 매끈한 내부 벽에 유상돌기를 포함한다. 저자들은 2일간의 좌하복부 불편감을 주소로 내원한 19세 여성에서 발생한 난소위체 장액성 경계성 종양을 경험하여 초음파, 컴퓨터단층촬영과 자기공명영상의 소견을 보고하고자 한다.

• Clinical and Experimental Reproductive Medicine
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• 제25권3호
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• pp.341-348
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• 1998

Objective: To determine the reproductive outcomes of women undergoing microsurgical reversal of tubal sterilization at age 36 years or older. Materials and Methods: A series of 133 patients who received microsurgical reversal of the previously sterilized fallopian tubes at Seoul National University Hospital from July, 1980 to January, 1992 was reviewed and evaluated for clinical characteristics, pregnancy rates, and factors influencing the outcome of tubal reversal. Results: Of 133 patients, 78 (58.6%) had been sterilized by laparoscopic cautery. Loss of children was a leading cause for tubal reversal. The mean interval from tubal sterilization to tubal reversal was 65.0 months. The overall pregnancy rate was 52.6% (70/133), and the mean interval was 9.4 months from tubal reversal to pregnancy. Excluding 7 patients who were lost to follow-up, 76 pregnancies were confirmed in 63 patients with the delivery rate per patient of 66.7% (42/63). There were no significant differences in age, duration of tubal sterilization, postoperative tubal length between pregnant and non-pregnant groups. Conclusions: Microsurgical reversal of tubal sterilization could be a justifiable method in women 36 years age or older.

• Clinical and Experimental Reproductive Medicine
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• 제39권4호
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• pp.161-165
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• 2012

Objective: To evaluate the effect of hysterosalpingo-contrast sonography (HyCoSy) on natural conception in the infertile patient. Methods: We conducted a prospective observational study recruiting 180 patients admitted to Infertility Center of Ferrara University from January 2010 to February 2012. The essential inclusion criteria was the couple's desire to perform only diagnostic evaluation on infertility causes and to wait for natural conception before proceeding with further management. Couples were investigated with hormonal profile, semen analysis and HyCoSy. Expected time for spontaneous pregnancy was 180 days from HyCoSy. First datation sonography of pregnancy was used calculating time elapsed from HyCoSy at conception. Results: Forty patients (22.2%) obtained spontaneous pregnancy within 6 months after HyCoSy. The mean of "conception time" was 75 days. The pregnancy rate was significantly higher in the first 30 days (45%) compared to other the months of observation (p<0.0005). Multiple linear regression analysis showed that maternal age and sterility duration proved independent variables in detecting the "conception time" after HyCoSy (t=3.742, p=0.001, t=2.371, p=0.02, respectively). Conclusion: A possible beneficial effect of HyCoSy is feasible especially in the days following its execution. This temporal correlation supports its therapeutic use.

• IMMUNE NETWORK
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• 제15권1호
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• pp.16-26
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• 2015

The female reproductive tract has two main functions: protection against microbial challenge and maintenance of pregnancy to term. The upper reproductive tract comprises the fallopian tubes and the uterus, including the endocervix, and the lower tract consists of the ectocervix and the vagina. Immune cells residing in the reproductive tract play contradictory roles: they maintain immunity against vaginal pathogens in the lower tract and establish immune tolerance for sperm and an embryo/fetus in the upper tract. The immune system is significantly influenced by sex steroid hormones, although leukocytes in the reproductive tract lack receptors for estrogen and progesterone. The leukocytes in the reproductive tract are distributed in either an aggregated or a dispersed form in the epithelial layer, lamina propria, and stroma. Even though immune cells are differentially distributed in each organ of the reproductive tract, the predominant immune cells are T cells, macrophages/dendritic cells, natural killer (NK) cells, neutrophils, and mast cells. B cells are rare in the female reproductive tract. NK cells in the endometrium significantly expand in the late secretory phase and further increase their number during early pregnancy. It is evident that NK cells and regulatory T (Treg) cells are extremely important in decidual angiogenesis, trophoblast migration, and immune tolerance during pregnancy. Dysregulation of endometrial/decidual immune cells is strongly related to infertility, miscarriage, and other obstetric complications. Understanding the immune system of the female reproductive tract will significantly contribute to women's health and to success in pregnancy.

• 혜화의학회지
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• 제9권1호
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• pp.267-285
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• 2000

According to the literatural study on the causes of Infertility in women, the results were as follows. 1. The causes of Infertility in women were arranged scholarly thoery during to Jin-Yuan era (金 元 時代) from Huang-Di-Nei-Jing(黃帝內經), and literatures after Ming-Qing era(明 淸 時代) divided and added one's own thoery since they choose preceding thoery. 2. In the Modern Medicine, the causes of Infertility in women are divided the product obstruction of Oocyte, the union obstruction of sperm and oocyte by abnormality of vagina, cervix, corpus, fallopian tubes, pelvic, and peritoneum, Endocrine factor, Immunologic factor, and Emotion factor. 3. In the Oriental Medicine, the causes of Infertility in women are attached importance to functional side as 'asthenia-cool of uterus'(子宮虛寒), 'deficiency of vital energy and blood'(氣血虛), 'deficiency of yin'(陰虛), 'impairement of seven emotion'(七情傷), 'disease of extra mierdians'(寄經病), and so forth; while on the other in the Modern Medicine, the causes of Infertility in women are attached importance to organic side as abnormality of uterus and ovary. 4. In the successive literatures, 'asthenia-cool of uterus'(子宮虛寒) occupied most frequency in the causes of Infertility in women and in the next obesity(體肥), 'deficiency of vital energy and blood'(氣血虛), menstrual irregularity(月經不調), deficiency of yin'(陰虛), 'impairement of seven emotion'(七情傷), emaciation(體瘦), 'disease of extra mierdians'(寄經病), and so forth occupied much frequency. 5. In the bodily form, obesity(體肥) and emaciation(體瘦) occupied comparatively more frequency.

• Clinical and Experimental Reproductive Medicine
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• 제14권1호
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• pp.1-6
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• 1987

The Radionuclide test (RN test) using radioactively labelled human albumin microspheres was developed recently to evaluate the patency and functional capacity of the fallopian tubes. 57 infertile women underwent this procedure as a part of their infertility work up. The results of the radionuclide evaluation were compared with those of the hysterosalpingography (HSG) and further the surgical findings of the laparoscopy and laparotomy. In 64.9%(37/57) of the cases, there was complete agreement between radionuclide test (RN test), hysterosalpingography(HSG) and surgical findings. In comparison with surgical findings, RN test showed a complete agreement rate of 89.4%(51/57), a partial agreement rate of 5.3%(3/57) and no agreement rate of 5.3%(3/57), respectively. Likewise, HSG revealed a complete agreement rate of 80.7%(46/57), a partial agreement rate of 10.5%(6/57) and no agreement 8.8%(5/57), respectively. It would appear that as opposed to the traditional HSG, RN test may give a better understanding of the functional capacity of the tube and may prove a useful method before and after tubal surgery.