• Nutrition Research and Practice
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• 제8권1호
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• pp.94-102
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• 2014

Diet attrition and failure of long term treatment are very frequent in obese patients. This study aimed to identify pre-treatment variables determining dropout and to customise the characteristics of those most likely to abandon the program before treatment, thus making it possible to modify the therapy to increase compliance. A total of 146 outpatients were consecutively enrolled; 73 patients followed a prescriptive diet while 73 followed a novel brief group Cognitive Behavioural Treatment (CBT) in addition to prescriptive diet. The two interventions lasted for six months. Anthropometric, demographic, psychological parameters and feeding behaviour were assessed, the last two with the Italian instrument VCAO Ansisa; than, a semi-structured interview was performed on motivation to lose weight. To identify the baseline dropout risk factors among these parameters, univariate and multivariate logistic models were used. Comparison of the results in the two different treatments showed a higher attrition rate in CBT group, despite no statistically significant difference between the two treatment arms (P = 0.127). Dropout patients did not differ significantly from those who did not dropout with regards to sex, age, Body Mass Index (BMI), history of cycling, education, work and marriage. Regardless of weight loss, the most important factor that determines the dropout appears to be a high level of stress revealed by General Health Questionnaire-28 items (GHQ-28) score within VCAO test. The identification of hindering factors during the assessment is fundamental to reduce the dropout risk. For subjects at risk, it would be useful to dedicate a stress management program before beginning a dietary restriction.

• Structural Engineering and Mechanics
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• 제64권3호
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• pp.347-352
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• 2017

The poor maintenance practice increases the possibility of system failure. Subsequently, the consequences of failure fall on the aspects of output, safety and healthy, environmental integrity, system quality, and customer satisfaction. Conditionbased maintenance is seen as a potential strategy to improve performance. Whereby, the key success factor of this maintenance strategy is identified as the system inspection. This study aims to investigate the association between system breakdown rate and frequency of inspection. A mixed method approach is implemented by distributing questionnaire and interviewing for data collection. Subsequently, descriptive analysis, correlation analysis and regression are adopted to analyse the collected data from 100 respondents and the results are validated with interview data of 10 interviewees. The research result establishes significant relationship between the system breakdown rate and the frequency of inspection. Additionally, the result of regression analysis confirms that the frequency of inspection is the significant predictor of system breakdown rate. Planning of accurate inspection frequency is crucial to secure the system performance. Hence, the research signifies the importance to carry out regular inspection towards the building systems and components. As a recommendation, the maintenance personnel should assess the risk criticality of the building systems. Then, continuously monitor the condition of critical building systems; regularly inspect the condition of non-critical building systems and randomly inspect all of them.

• 한국지반공학회논문집
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• 제23권3호
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• pp.111-121
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• 2007

지진하중의 불확실성을 평가할 수 있는 신뢰성기반 해석기법을 제시한다. 이 기법은 종래의 한계평형법과 뉴막-형식의 변형량 계산기법에 확률개념을 도입하였으며 피해 위험성을 몬테칼로 시뮬레이션 해석기법으로 계산한다. 지진파를 작성하고 이들을 사면 내진 해석에 사용하고자 확률변수 프로세스와 RMS 재해 기법을 도입하였다. 지반성질의 변동성과 통계오차도 고려하였다. 신뢰성 해석 결과 지진활동이 활발한 지역에서는, 계산된 사면파괴 위험성과 과도한 영구변형의 관점에서 비교할 때 지진재해 평가가 더 중요한 사항이며, 재료성질의 모사방법의 차이는 상대적으로 영향이 적다는 사실이 밝혀졌다. 이 결과는 원형 및 비원형 형태의 활동면 파괴에 모두 해당된다.

• Radiation Oncology Journal
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• 제33권3호
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• pp.198-206
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• 2015

Purpose: We evaluated the prognostic factors and clinical outcomes of 56 patients with vulvar cancer treated with curative radiotherapy (RT) or concurrent chemoradiotherapy. Materials and Methods: Overall survival (OS) and disease-free survival (DFS) were assessed retrospectively. Prognostic factors evaluated included age, International Federation of Gynecology and Obstetrics (FIGO) stage, TNM classification, tumor size, treatment modality, RT duration, and RT field. The association between the tumor human papillomavirus (HPV) status and survival was analyzed in 35 patients. Results: During the median follow-up of 2.8 years (range, 0.3 to 18.9 years), 21 patients (37.5%) experienced treatment failure. Fifteen patients (27%) had local failure: nine (16%) local failure only, three (5%) locoregional failure, two (4%) local and distant failure, and one (2%) locoregional and distant failure. Of 56 patients, seven (13%) had persistent disease at the first follow-up at 2 months and all but one died within a year after completing RT. The 5-year OS and DFS were 51.6% and 44.0%, respectively. In multivariate analysis, clinical size ${\geq}3$ cm predicted a poor prognostic factor for DFS (p = 0.040) and age (${\geq}70years$) was poor prognostic for DFS (p = 0.032) and OS (p = 0.048). Patients with HPV-positive tumors tended to have better 5-year OS and DFS, but the differences were not significant statistically. Conclusion: Clinical size ${\geq}3$ cm was a significant prognostic factor for DFS. However, age was the most important prognostic factor for DFS and OS in patients treated with curative RT. Further studies are needed to determine which treatment should be considered for old age ${\geq}70years$.

• 한국건설관리학회논문집
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• 제14권5호
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• pp.92-102
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• 2013

PF사업은 민간의 투자를 유치하여 국가 경제와 산업의 발전에 도움을 주려는 목적으로 수행되는 프로젝트 발주방식의 한 형태이다. 그러나 국내의 경우 개발이익 극대화라는 측면만을 고려함으로 인하여 무분별한 PF사업의 급증과 최근의 금융위기의 여파로 인하여 사업의 중단이 속출하고 있다. 이러한 주된 원인은 PF사업을 객관적으로 정량화하고 이를 분석하여 사전에 발생 가능한 리스크를 차단하려는 노력이 미흡한 결과이다. 본 연구의 목적은 PF사업의 건전성을 평가할 수 있는 방법론을 제안하기 위한 사전 연구로 PF사업의 성공에 영향을 끼치는 원인을 분류하여 세부요소를 파악하고 이를 바탕으로 PF사업의 리스크를 평가할 수 있는 정량적인 체계를 제안하는데 있다. 본 연구는 PF사업의 성공요인과 실패요인을 선행연구와 면담조사를 바탕으로 5개영역, 15개 항목, 104개의 영향인자를 도출하였고, 전문가 설문조사를 통해 영향정도를 검증하였다. 후속 면담조사를 통해 설문조사 결과에 대한 분석을 실시하였고, PF 사업의 건전성 평가를 위한 도구로 활용이 될 경우 PF 개발사업의 건전성 평가에 많은 도움이 될 수 있을 것으로 판단되며, PF 사업에 대한 객관적인 평가 도구 개발 시 유용한 기초자료로 이용될 수 있을 것으로 기대된다.

• Geomechanics and Engineering
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• 제17권1호
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• pp.109-118
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• 2019

The movement of soil along a slope during rainfall can cause serious economic damage and can jeopardize human life. Accordingly, predicting slope stability during rainfall is a major issue in geotechnical engineering. Due to rainwater penetrating the soil, the negative pore water pressure will decrease, in turn causing a loss of shear strength in the soil and ultimately slope failure. More seriously, many constructions such as houses and transmission towers built in/on slopes are at risk when the slopes fail. In this study, the numerical simulation using 2D finite difference program, which can solve a fully coupled hydromechanical problems, was used to evaluate the effects of soil properties, rainfall conditions, and the location of a foundation on the slope instability and slope failure mechanisms during rainfall. A slope with a transmission tower located in Namyangju, South Korea was analyzed in this study. The results showed that the correlation between permeability and rainfall intensity had an important role in changing the pore water pressure via controlling the infiltrated rainwater. The foundation of the transmission tower was stable during rainfall because the slope failure was estimated to occur at the toe of the slope, and did not go through the foundation.

• Journal of Chest Surgery
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• 제15권2호
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• pp.204-212
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• 1982

The presence of left atrial thrombus in mitral stenosis has been reported to be associated with several factors. These are age, sex, presence of atrial fibrillation, episodes of congestave heart failure, calcification of mitral valve, embolic episode, etc. Since none of these single factor has been always related to the presence of left atrial thrombus, related risk factors to left atrial thrombosis were studied in patients with mitral stenosis using chi square test. We had operated on 191 cases of mitral valvular heart disease from Jan. 1978 to June 1981 at Severance Hospital, Yunsei University College of Medicine. The left atrial thrombi were present in 41 cases among 191 cases of mitral valvular heart disease and it was present in 31 cases among 89 cases of pure mitral stenosis. Only 10 cases among 74 cases of mitral stenoregurgitation had left atrlal thrombi, whereas no left atrlal thrombus was found in patients with pure mitral regurgitation. Related risk factors studied herein were sex, episodes of congestive heart failure, atrial fibrillation, pulmonary capillary wedge pressure, mitral valve area calculated by Gorlin and Gorlin`s formula cardiac output and left atrial dimension by echocardiogram. In this study presence of atrial fibrillation was deemed to be one of the most potential risk factors and other factors of age, duration of symptoms, episode of embolization, calclfication of mitral valve, associated aortic and tricuspid valve disease, ejection fraction of left ventricle by cineangiocardiogram and echocardiogram were not significantly related to the presence of left atrlal thrombi in a statistical viewpoint.

• 한국가스학회지
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• 제23권5호
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• pp.35-43
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• 2019

플랜트시설의 핵심부품인 산업용 밸브에 대한 기존안전관리는 인력에 의해 관리되고 있으며 점검 영역이 넓고 시설물의 특성상 제한된 접근성을 가지고 있기 때문에 어려움이 있다. 플랜트 시설의 수많은 산업용 밸브에서 누출 및 고장 발생 시 생산중단, 독성물질 및 가연성 가스의 누출 및 폭발로 인한 인명피해, 사고 위치 파악 어려움 등의 문제점이 발생되기 때문에 사물인터넷(IoT) 기술을 기반으로 한 안전관리 및 제어 시스템이 필요하다. 이 연구에서는 IoT 기반 무선통신을 통한 산업용 밸브의 안전관리 및 액츄에이터 제어 시스템 개발 내용 중에서 위험요소 예측기술 개발과 관련 된 내용이다. 밸브의 구조적 특성 분석을 하고 고장데이터, 문헌 등으로 부터 주요 위험요소 분석, 위험요소 원인분석 및 사고시나리오 분석을 통해 주요 위험요소로 인한 사고를 예방하기 위해 IoT 기반 산업용 밸브의 안전관리 기법을 개발하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권7호
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• pp.4273-4278
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• 2013

Objective: We aimed to define clinicopathologic risk factors associated with regional recurrence (RR) and thus the effectiveness of postoperative radiotherapy (PORT) for neck control for head and neck squamous cell carcinomas (HNSCCs) with differing cervical lymph node status. Methods: A retrospective study was performed in 196 HNSCC patients with pathologically positive neck node (N+) to evaluate the high-risk factors for RR and to define the role of PORT in control after neck dissection and postoperative radiotherapy (PORT). Results: Overall, the RR rate after neck dissection and PORT was 29%. Extracapsular spread (ECS) was confirmed to be the only independent risk factor for RR. There were no significant risk factors associated with RR in the ECS- group. The 5-year disease-specific survival rate was 45%, which descended to 10% with the emergence of RR. Conclusions: ECS remains a determined risk factor for RR after neck dissection and PORT in patients with N+. PORT alone is not adequate for preventing RR in the neck with ECS after neck dissection. More intensive postoperative adjuvant therapies, especially combined chemotherapy and radiotherapy, are needed to prevent regional failure in HNSCC patients with ECS.

• Journal of Korean Neurosurgical Society
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• 제60권5호
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• pp.567-576
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• 2017

Objective : Preoperative parameters including the T1 slope (T1S) and C2-C7 sagittal vertical axis (SVA) have been recognized as predictors of kyphosis after laminoplasty, which is accompanied by posterior neck muscle damage. The importance of preoperative parameters has been under-estimated in anterior cervical discectomy and fusion (ACDF) because there is no posterior neck muscle damage. We aimed to determine whether postoperative subsidence and pseudarthrosis could be predicted according to specific parameters on preoperative plain radiographs. Methods : We retrospectively analyzed 41 consecutive patients (male : female, 22 : 19; mean age, $51.15{\pm}9.25years$) who underwent ACDF with a stand-alone polyether-ether-ketone (PEEK) cage (>1 year follow-up). Parameters including SVA, T1S, segmental angle and range of motion (ROM), C2-C7 cervical angle and ROM, and segmental inter-spinous distance were measured on preoperative plain radiographs. Risk factors of subsidence and pseudarthrosis were determined using multivariate logistic regression. Results : Fifty-five segments (27 single-segment and 14 two-segment fusions) were included. The subsidence and pseudarthrosis rates based on the number of segments were 36.4% and 29.1%, respectively. Demographic data and fusion level were unrelated to subsidence. A greater T1S was associated with a lower risk of subsidence (p=0.017, odds ratio=0.206). A cutoff value of T1S<$28^{\circ}$ significantly predicted subsidence (sensitivity : 70%, specificity : 68.6%). There were no preoperative predictors of pseudarthrosis except old age. Conclusion : A lower T1S (T1S<$28^{\circ}$) could be a risk factor of subsidence following ACDF. Surgeons need to be aware of this risk factor and should consider various supportive procedures to reduce the subsidence rates for such cases.