• Title/Summary/Keyword: Failure risk factor

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Risk Factors of Treatment Failure in Diabetic Foot Ulcer Patients

  • Lee, Kyung Mook;Kim, Woon Hoe;Lee, Jang Hyun;Choi, Matthew Seung Suk
    • Archives of Plastic Surgery
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    • 제40권2호
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    • pp.123-128
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    • 2013
  • Background Some diabetic feet heal without complication, but others undergo amputation due to progressive wounds. This study investigates the risk factors for amputation of diabetic feet. Methods A total of 55 patients who visited our institution from 2008 to 2012 were included in the study. The patients with abnormal fasting blood sugar levels, lower leg vascularity, and poor nutrition were excluded from the study group, and the wound states were unified. The patients were categorized into a treatment success group (n=47) and a treatment failure group (n=8), and their hemoglobin A1C (HgA1C), C-reactive protein (CRP), white blood cell count (WBC), and serum creatinine levels were analyzed. Results The initial CRP, WBC, and serum creatinine levels in the treatment failure group were significantly higher than that of the treatment success group, and the initial HgA1C level was significantly higher in the treatment success group. The CRP and WBC levels of both groups changed significantly as time passed, but their serum creatinine levels did not. Conclusions The initial CRP, WBC, and serum creatinine levels were considered to be risk factors for amputation. Among them, the serum creatinine level was found to be the most important predictive risk factor. Because serum creatinine represents the renal function, thorough care is needed for the feet of diabetic patients with renal impairment.

Case Study of Slope Investigation on the Cretaceous Sedimentary Rocks Using the Geological Cross-Sections

  • Ihm, Myeong-Hyeok;Kim, Woo-Seok;Kwon, Oil
    • 지질공학
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    • 제31권4호
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    • pp.463-478
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    • 2021
  • The subjects of the study are the sedimentary rock slope of the Mesozoic Gyeongsang Supergroup, which has a high risk of failure. The orientation of the slope-face represents a variety of changing characteristics. The rocks of the slope shall be sandstone, siltstone and dacite, and discontinuities shall develop beddings, shear joints, extension joints, and dacite dyke boundary planes. The type and scale of failure varies depending on the type of rock and the strike/dip of the discontinuities, but the toppling failure prevails. Based on the face-mapping data, SMR, physical and mechanical testing of rocks, analysis and review of the stereonet projections and the critical equilibrium analysis, all four representative sections required a countermeasure method because the acceptable safety factor during dry and rainy seasons were far below Fs = 1.5 and Fs = 1.2. After applying the countermeasure method, both the dry and wet conditions of the slope exceeded the allowable safety factor. In particular, the face-mapping data of the slope-face, the geological cross-sections of several representative sections perpendicular to the slope-face, and the critical equilibrium analysis and the presentation of countermeasure methods that have been reviewed based on them are expected to be reasonable tools for the slope stability. In addition, it will be possible to use it as basic data for performance evaluation for slope maintenance.

Clinical outcomes of preimplantation genetic testing for aneuploidy in high-risk patients: A retrospective cohort study

  • Jun Woo Kim;So Young Lee;Chang Young Hur;Jin Ho Lim;Choon Keun Park
    • Clinical and Experimental Reproductive Medicine
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    • 제51권1호
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    • pp.75-84
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    • 2024
  • Objective: The purpose of this study was to evaluate the impact of preimplantation genetic testing for aneuploidy (PGT-A) on clinical outcomes among high-risk patients. Methods: This retrospective study involved 1,368 patients and the same number of cycles, including 520 cycles with PGT-A and 848 cycles without PGT-A. The study participants comprised women of advanced maternal age (AMA) and those affected by recurrent implantation failure (RIF), recurrent pregnancy loss (RPL), or severe male factor infertility (SMF). Results: PGT-A was associated with significant improvements in the implantation rate (IR) and the ongoing pregnancy rate/live birth rate (OPR/LBR) per embryo transfer cycle in the AMA (39.3% vs. 16.2% [p<0.001] and 42.0% vs. 21.8% [p<0.001], respectively), RIF (41.7% vs. 22.0% [p<0.001] and 47.0% vs. 28.6% [p<0.001], respectively), and RPL (45.6% vs. 19.5% [p<0.001] and 49.1% vs. 24.2% [p<0.001], respectively) groups, as well as the IR in the SMF group (43.3% vs. 26.5%, p=0.011). Additionally, PGT-A was associated with lower overall incidence rates of early pregnancy loss in the AMA (16.7% vs. 34.3%, p=0.001) and RPL (16.7% vs. 50.0%, p<0.001) groups. However, the OPR/LBR per total cycle across all PGT-A groups did not significantly exceed that for the non-PGT-A groups. Conclusion: PGT-A demonstrated beneficial effects in high-risk patients. However, our findings indicate that these benefits are more pronounced in carefully selected candidates than in the entire high-risk patient population.

Factors Associated with the Stability of Two-part Mini-implants for Intermaxillary Fixation

  • Kim, Seong-Hun;Seo, Woon-Kyung;Lee, Won;Kim, In-Soo;Chung, Kyu-Rhim;Kook, Yoon-Ah
    • Journal of Korean Dental Science
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    • 제2권2호
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    • pp.24-30
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    • 2009
  • Two component orthodontic C-implants have been introduced as intermaxillary fixation (IMF) screws in cases of periodontal problems with bone loss, severely damaged teeth, or short roots. This retrospective research sought to investigate the complications and risk factors associated with the failure of two-part C-implants for IMF cases and to show the possible indications compared to one-component mini-implants. The study sample consisted of 46 randomly selected patients who had a total of 203 implants. Pearson chi-square tests of independence were used to test for associations among categorical variables. At least 19 of the total 203 implants failed (9.3%). There was no significant difference in implant failure due to gender, oral hygiene, and placement, although a significant difference due to soft tissue characteristics and root contact was observed. The two-component design of the mini-implant is reliable for difficult IMF cases. Note, however, that the factors influencing implant failure were found to be age, root damage, and condition of soft tissues.

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급성신부전이 발생한 중증 외상 환자에서 저분자량헤파린 투여 후 발생한 심각한 출혈 합병증 (Serious Bleeding Complication Due to the Use of Low-molecular-weight heparin to treat a Traumatic Patient with Acute Renal Failure)

  • 경규혁;김운원;박성진;김기훈;김진수;박종권
    • Journal of Trauma and Injury
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    • 제24권2호
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    • pp.164-167
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    • 2011
  • Trauma is an important risk factor for a pulmonary thromboembolism, and anticoagulation is essential to prevent deep vein thrombosis (DVT) in patients with trauma. Low-molecular-weight heparin (LMWH) is excreted in the kidney; therefore, using LMWH in patients with renal insufficiency may increase the risk of bleeding complication. The following case describes a 55-year-old traffic accident victim who had massive bleeding and underwent a laparotomy for bleeding control. The patient had acute renal failure, and enoxaparin was administered for the prophylaxis of DVT. Although the patient suffered from serious complications such as pericardial hematoma, the patient recovered without sequellae and was discharged at day 84.

Senning 및 Mustard 수술후 장기 성적 (Late Results of the Senning and Mustard Operations for TGA in Children)

  • 서경필
    • Journal of Chest Surgery
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    • 제22권1호
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    • pp.32-41
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    • 1989
  • We scrutinized the 64 cases of TGA and Taussig-Bing anomaly who underwent Senning and Mustard operations from Jan. 1981 to May 1988. The ratio of male to female was 45; 19, and the age at operation varied from 2 months to 18 years [mean 18.9*32.9 months]. The in-hospital mortality was in 24 cases [37.5%] and the major causes were myocardial failure and congestive heart failure associated with arrhythmias. The risk factors for hospital mortality were complex TGA, prolonged bypass time and high postoperative CVP. In addition, mortality increased during the first year the procedure was used. Late mortality occurred in 6 cases and the major causes was congestive heart failure, and there was not any significant risk factor noted in late mortality. Early arrhythmia developed in 37.5%, all of which were transient and self limited and 7 cases of early mortality were related to the arrhythmias. Late arrhythmias developed in 8 cases, but 7 cases were transient. One case died with junctional tachycardia. Of significance the one case that died late by arrhythmia had a similar junctional tachycardia in the early postoperative period. The survival rate in all cases disregarding initial in-hospital mortality 1YSR 89.8% and 5YSR 84.3%, but because of short duration of follow up this is not significant. We concluded that early hospital mortality could be decreased by operating at an earlier age and by adjusting the appropriate operation method.

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쉴드 TBM 터널에 적용 가능한 리스크 관리: II. 리스크 분석 방법 (Risk management applicable to shield TBM tunnel: II. Risk analysis methodology)

  • 현기창;민상윤;문준배;정경환;이인모
    • 한국터널지하공간학회 논문집
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    • 제14권6호
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    • pp.683-697
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    • 2012
  • 본 논문에서는 쉴드 TBM 터널에서 적용 가능한 리스크 분석 방법을 연구하였다. FTA 방법을 통해 리스크 아이템과 각각의 발생확률을 확인하고 AHP 방법을 통해 각각의 리스크 아이템의 영향도를 구하였다. 마지막으로 각각의 리스크 아이템의 리스크 레벨을 평가할 수 있었다. 개발된 방법을 EPB 쉴드 터널이 사용된 서울 지하철 현장에 적용하여 리스크 분석 결과가 현장 데이터에 부합하는 합리적 결과임을 검증하였다.

파괴확률을 이용한 철도절개면의 위험도 평가 (Risk Assessment of Slopes using Failure Probability in Korean Railways)

  • 김현기;김수삼
    • 한국철도학회논문집
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    • 제11권2호
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    • pp.158-164
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    • 2008
  • 강우침투는 지반의 모관흡수력을 감소시켜 저항력의 감소를 유발하며, 자중 증가로 인하여 구동력의 증가를 발생시켜, 사면 붕괴를 발생시킨다. 각종 기준에서 제시된 안전율을 만족한다해도 강우에 의한 사면붕괴는 자주 발생하고 있으며, 막대한 사회적 손실을 발생시키고 있다. 이와 같은 사면붕괴 발생의 주요 원인중에 하나는 사면을 구성하는 토질정수에 대한 불확실성을 고려하지 못했기 때문이며, 이를 보완하기 위하여 신뢰성해석의 기법을 도입을 검토하였다. 신뢰성해석은 지반물성과 결과적 부산물인 안전율의 확률분포특성을 고려할 수 있는 장점이 있으며, 결과물로 산출되는 파괴확률을 위험도관리에 확장하여 적용할 수 있다. 본 연구에서는 철도사면 8개소에 대하여 각종 기준에서 제시하고 있는 기준을 적용하여 신뢰성해석을 시행한 후 그 결과를 분석하였으며, 철도영업선에 대한 손실을 고려하여 철도사면의 위험도관리가 정량적으로 시행될 수 있음을 보였다.

Logistic 회귀모형과 GIS기법을 활용한 접도사면 붕괴확률위험도 제작 (Hazard Map of Road Slope Using a Logistic Regression Model and GIS)

  • 강호윤;곽영주;강인준;장용구
    • 한국측량학회:학술대회논문집
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    • 한국측량학회 2006년도 춘계학술발표회 논문집
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    • pp.339-344
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    • 2006
  • Slope failures are happen to natural disastrous when they occur in mountainous areas adjoining highways in Korea. The accidents associated with slope failures have increased due to rapid urbanization of mountainous areas. Therefore, Regular maintenance is essential for all slope and conducted to maintain road safety as well as road function. In this study, we take priority of making a database of risk factor of the failure of a slope before assesment and analysis. The purpose of this paper is to recommend a standard of Slope Management Information Sheet(SMIS) like as Hazard Map. The next research, we suggest to pre-estimated model of a road slope using Logistic Regression Model.

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Characteristics of Active Tuberculosis Patients Requiring Intensive Care Monitoring and Factors Affecting Mortality

  • Filiz, Kosar A.;Levent, Dalar;Emel, Eryuksel;Pelin, Uysal;Turkay, Akbas;Aybuke, Kekecoglu
    • Tuberculosis and Respiratory Diseases
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    • 제79권3호
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    • pp.158-164
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    • 2016
  • Background: One to three percent of cases of acute tuberculosis (TB) require monitoring in the intensive care unit (ICU). The purpose of this study is to establish and determine the mortality rate and discuss the causes of high mortality in these cases, and to evaluate the clinical and laboratory findings of TB patients admitted to the pulmonary ICU. Methods: The data of patients admitted to the ICU of Yedikule Chest Diseases and Chest Surgery Education and Research Hospital due to active TB were retrospectively evaluated. Demographic characteristics, medical history, and clinical and laboratory findings were evaluated. Results: Thirty-five TB patients (27 males) with a median age of 47 years were included, of whom 20 died within 30 days (57%). The Acute Physiology and Chronic Health Evaluation II (APACHE II) and Sequential Organ Failure Assessment (SOFA) scores were significantly higher, and albumin and $PaO_2/FIO_2$ levels were significantly lower, and shock, multiple organ failure, the need for invasive mechanical ventilation and drug resistance were more common in the patients who died. The mortality risk was 7.58 times higher in the patients requiring invasive mechanical ventilation. The SOFA score alone was a significant risk factor affecting survival. Conclusion: The survival rate is low in cases of tuberculosis treated in an ICU. The predictors of mortality include the requirement of invasive mechanical ventilation and multiple organ failure. Another factor specific to TB patients is the presence of drug resistance, which should be taken seriously in countries where there is a high incidence of the disease. Finding new variables that can be established with new prospective studies may help to decrease the high mortality rate.