Journal of the Korea Academia-Industrial cooperation Society
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v.13
no.12
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pp.5860-5866
/
2012
BOLD technique in functional MRI has to apply multiple stimulations. However as the stimulation time increases failure rates rise. In this study we are proposing proper number of stimulations through our experiments. Ten normal people underwent functional MRI hand motor sanning and the paradigms were designed from first to seventh stimulation. Under Philips Intera Achieva 3.0T MR system and Invivo cop's Eloquence equipment, activation periods and rest periods were repeated ten times each, using BOLD EPI technique. Primary hand motor area stimulation and number of clusters, activation rates and number of activated clusters in and outside the region of interest were compared to each other. Number of clusters in region of interest was lower than others at second stimulation and became static from third stimulation. The stimulated ratios were elevated as the number of stimulations were increased but it was not proportional. Number of clusters outside the ROI became static from the third stimulation and started increasing from sixth stimulation. As results, given the activation ratios of ROI and out side the ROI, three times stimulation was the most appropriate because it does not affect accuracy, also decreasing the fatigue of patients by with the decreased scanning time.
Park, Duhee;Lee, Tae-Hyung;Kim, Hansup;Park, Jeong-Seon
Journal of Korean Tunnelling and Underground Space Association
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v.18
no.2
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pp.119-128
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2016
In a performance-based design, the structural safety is estimated from pre-defined damage states and corresponding damage indices. Both damage states and damage indices are well defined for above-ground structures, but very limited studies have been performed on underground structures. In this study, we define the damage states and damage indices of a cut-and-cover box tunnel which is one of typical structures used in metro systems, under a seismic excitation from a series of inelastic frame analyses. Three damage states are defined in terms of the number of plastic hinges that develop within the structure. The damage index is defined as the ratio of the elastic moment to the yield moment. Through use of the proposed index, the inelastic behavior and failure mechanism of box tunnels can be simulated and predicted through elastic analysis. In addition, the damage indices are linked to free-field shear strains. Because the free-field shear strain can be easily calculated from a 1D site response analysis, the proposed method can be readily used in practice. Further studies are needed to determine the range of shear strains and associated uncertainties for various types of tunnels and site profiles. However, the inter-linked platform of damage state - damage index - shear wave velocity - shear strain provides a novel approach for estimating the inelastic response of tunnels, and can be widely used in practice for seismic designs.
Journal of the Korean Society for information Management
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v.35
no.1
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pp.33-59
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2018
This study draws on the current momentum to diversify open government data research through multidimensional scaling and model development. It formulates a quality assessment model applicable to library open data, taking into consideration the paucity of such research in the field. The model was developed using the Delphi method and verified for validity and reliability on the basis of a survey administered to library open data users. The results of the fourth round exhibited an average of 4.00 for all measured elements and a minimum validity of .75, rendering the model appropriate for use in quality assessments of library open data. The convergence and stability results provided by the expert panel fell below .50, confirming that there was no need to conduct further surveys in order to establish the validity of the Delphi method. The model's reliability likewise garnered results of .60 and above in all three dimensions. This Model completed with the input of the Delphi panel was put through a verification process in which library open data users such as domestic and international librarians, developers, and open data activists reviewed the model for validity and reliability. The model scored low on validity on account of its failure to load all measure factors and elements pertaining to the three dimensions. Reliability results, on the other hand, were at 0.6 and above for all dimensions and measured elements.
Kim, Dong Hun;Kim, Sang Uk;Sung, Jae Hoon;Lee, Dong Hoon;Yi, Ho Jun;Lee, Sang Won
Journal of Korean Neurosurgical Society
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v.60
no.6
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pp.654-660
/
2017
Objective : Mechanical thrombectomy is increasingly being used for the treatment of acute ischemic stroke. The population over 80 years of age is growing, and many of these patients have acute infarction; however, these patients are often excluded from clinical trials, so the aim of this study was to compare the functional outcomes and complication rates in very elderly patients (age ${\geq}80$ years) and aged patients (60-79 years) treated with mechanical thrombectomy. Methods : Between January 2010 and June 2015, we retrospectively reviewed 113 senior patients (over 60 years old) treated at our institution for acute ischemic stroke with mechanical thrombectomy. They were divided into a very elderly (${\geq}80$ years) and aged (60-79 years) group, with comparisons in recanalization rates, complications, death and disability on discharge be reported. Results : The mean age was 70.3 years in the aged group and 83.4 years in the very elderly group. Elderly patients had higher rates of mechanical thrombectomy failure than the younger group (40% vs. 14%; odds ratio [OR] 4.1; 95% confidence interval [CI] 1.4-11.9; p=0.012). Results from thrombolysis in cerebral ischemia and modified Rankin scale at discharge were worse in the older group (p=0.005 and 0.023 respectively). There were no differences in mortality rate or other complications, but infarction progression rates were significantly higher in the very elderly group. (15% vs. 2.2%; OR 8.0; 95% CI 1.2-51.7; p=0.038). The majority (92.3%) of the patients who failed in aged group were not successful after several trials. However, in half (4 of 8) of the very elderly group, the occlusion site could not be accessed. Conclusion : Patients older than 80 years of age undergoing mechanical thrombectomy for acute infarction were more difficult to recanalize due to inaccessible occlusion sites and had a higher rate of infarction progression, However, mortality and other complications were similar to those in younger patients.
Journal of the Korea Academia-Industrial cooperation Society
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v.18
no.3
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pp.673-680
/
2017
sump pump is a system that draws in water that is stored in a dam or reservoir. They are used to pump large amounts of water for cooling systems in large power plants, such as thermal and nuclear plants. However, if the flow and sump pump ratio are small, the flow rate increases around the inlet port. This causes a turbulent vortex or swirl flows. The turbulent flow reduces the performance and can cause failure. Various methods have been devised to solve the problem, but a correct solution has not been found for low water level. The most efficient solution is to install an anti-vortex device (AVD) or increase the length of the sump inlet, which makes the flow uniform. This paper presents a computational fluid dynamics (CFD) analysis of the flow characteristics in a sump pump for different sump inlet lengths and AVD types. Modeling was performed in three stages based on the pump intake, sump, and pump. For accurate analysis, the grid was made denser in the intake part, and the grid for the sump pump and AVD were also dense. 1.2-1.5 million grid elements were generated using ANSYS ICEM-CFD 14.5 with a mixture of tetra and prism elements. The analysis was done using the SST turbulence model of ANSYS CFX14.5, a commercial CFD program. The conditions were as follows: H.W.L 6.0 m, L.W.L 3.5, Qmax 4.000 kg/s, Qavg 3.500 kg/s Qmin 2.500 kg/s. The results of analysis by the vertex angle and velocity distribution are as follows. A sump pump with an Ext E-type AVD was accepted at a high water level. However, further studies are needed for a low water level using the Ext E-type AVD as a base.
Park, Dohyun;Kim, Hyunwoo;Park, Jung-Wook;Park, Eui-Seob;Sunwoo, Choon
Tunnel and Underground Space
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v.24
no.2
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pp.155-165
/
2014
Multiple thermal energy storage (TES) caverns can be used for storing thermal energy on a large scale and for a high-aspect-ratio heat storage design to provide good thermal performance. It may also be necessary to consider the use of multiple caverns with a reduced length when a single, long tunnel-shaped cavern is not suitable for connection to aboveground heat production and injection equipments. When using multiple TES caverns, the separation distance between the caverns is one of the significant factors that should be considered in the design of storage space, and the optimal separation distance should be determined based on a quantitative stability criterion. In this paper, we described a numerical approach for determining the optimal separation distance between multiple caverns for large-scale TES utilization. For reliable stability evaluation of multiple caverns, we employed a probabilistic method which can quantitatively take into account the uncertainty of input parameters by probability distributions, unlike conventional deterministic approaches. The present approach was applied to the design of a conceptual TES model to store hot water for district heating. The probabilistic stability results of this application demonstrated that the approach in our work can be effectively used as a decision-making tool to determine the optimal separation distance between multiple caverns. In addition, the probabilistic results were compared to those obtained through a deterministic analysis, and the comparison results suggested that care should taken in selecting the acceptable level of stability when using deterministic approaches.
Background: All currently available mechanical and bioprosthetic valves are associated with various types of deterioration leading to dysfunction and/or valvular complications. Reoperation on prosthetic heart valves is increasingly under consideration for both clinical and prophylactic indications. This review was conducted to determine the factors affecting the risk of reoperation for prosthetic valve replacement. Material and method: From January 1985 to July 1996, 124 patients underwent reoperation on prosthetic heart valves, and 3 patients had a second valve reoperation. The causes of reoperation were prosthetic valve failure(96 cases, 77.4%), prosthetic valve thrombosis(16 cases, 12.9%), prosthetic valve endocarditis(7 cases, 5.6%) and paravalvular leak(5 cases, 4.1%). This article is based on the analysis of the experience with particular emphasis on the preoperative risks affecting the outcome of the reoperation. Result: Overall hospital mortality rate was 8.9%(11/124). Low cardiac output was the most common cause of death(70.6%). Left ventricular systolic dimension(p=0.001), New York Heart Association functional class IV(p=0.003) and serum creatinine level(p=0.007) were the independent risk factors, but age, sex and cardiothoracic ratio did not have any influence on the operative mortality. Follow-up period was ranged from 3 to 141 months (mean, 50.6 months). A late mortality rate was 1.8%. Conclusion: The surgical risk of reoperation on heart valve prostheses in the advanced NYHA class patients is higher, therefore reoperation is recommended before the hemodynamic impairment become severe.
Doh, Re-Mee;Kim, Sungtae;Keum, Ki Chang;Kim, Jun Won;Shim, June-Sung;Jung, Han-Sung;Park, Kyeong-Mee;Chung, Moon-Kyu
The Journal of Advanced Prosthodontics
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v.8
no.5
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pp.363-371
/
2016
PURPOSE. On maxillofacial tumor patients, oral implant placement prior to postoperative radiotherapy can shorten the period of prosthetic reconstruction. There is still lack of research on effects of post-implant radiotherapy such as healing process or loading time, which is important for prosthodontic treatment planning. Therefore, this study evaluated the effects of post-implant local irradiation on the osseointegration of implants during different healing stages. MATERIALS AND METHODS. Custom-made implants were placed bilaterally on maxillary posterior edentulous area 4 weeks after extraction of the maxillary first molars in Forty-eight Sprague-Dawley rats. Experimental group (exp.) received radiation after implant surgery and the other group (control) didn't. Each group was divided into three sub-groups according to the healing time (2, 4, and 8 week) from implant placement. The exp. group 1, 2 received 15-Gy radiation 1 day after implant placement (immediate irradiation). The exp. group 3 received 15-Gy radiation 4 weeks after implant placement (delayed irradiation). RESULTS. The bone mineral density (BMD) was significantly lower in the immediate irradiation groups. BMD was similar in the delayed irradiation group and the control group. The irradiated groups exhibited a lower bone-to-implant contact ratio, although the difference was not statistically significant. The irradiated groups also exhibited a significantly lower bone volume and higher empty lacuna count than the control groups. No implant failure due to local irradiation was found in this study. CONCLUSION. Within the limits of this study, the timing of local irradiation critically influences the bone healing mechanism, which is related to loading time of prostheses.
Han, Sang-Whan;Kee, Seong-Hoon;Kang, Tomas H.K.;Cho, Jong;Lee, Li-Hyung
Journal of the Korea Concrete Institute
/
v.18
no.5
s.95
/
pp.595-602
/
2006
An experimental study was conducted to investigate seismic behaviour of post-tensioned(PT) exterior slab-column connections used for the purpose to resist gravity loads only. For these, 2/3-scale, two PT post-tensioned exterior connections with two different tendon arrangement patterns and one conventional reinforced concrete(RC) exterior connection was tested under quasi-static, uni-directional reversed cyclic loading. During the lateral testing, gravity forces transferred to the column were kept constant to closely simulate a moment to shear ratio of a real building. One of the objectives of this study was to assess the necessity and/or the quantity of bottom bonded reinforcement needed to resist moment reversal which would occur under significant inelastic deformations of the adjacent lateral force resisting systems. The ACI 318 and 352 provisions for structural integrity were applied to provide the bottom reinforcement passing through the column for the specimens. Prior test results were also collected to conduct comparative studies for some design parameters such as the tendon arrangement pattern, the effect of post-tensioning forces and the use of bottom bonded reinforcement. Consequently, the impact of tendon arrangement on the seismic performance of the PT connection, that is lateral drift capacity and ductility, dissipated energy and failure mechanism, was considerable. Moreover, test results showed that the amount of bottom reinforcement specified by ACI 352. 1R-89 was sufficient for resisting positive moments arising from moment reversal under reversed cyclic loads. Shear strength of the tested specimens was more accurately predicted by the shear strength equation(ACI 318) considering the average compressive stress over the concrete($f_{pc}$) due to post-tensioning forces than that without considering $f_{pc}$.
Shear friction strength model of concrete was proposed to explain the direct friction mechanism at the concrete interfaces intersecting two structural elements. The model was derived from a mechanism analysis based on the upper-bound theorem of concrete plasticity considering the effect of transverse reinforcement and applied axial loads on the shear strength at concrete interfaces. Concrete was modelled as a rigid-perfectly plastic material obeying modified Coulomb failure criteria. To allow the influence of concrete type and maximum aggregate size on the effectiveness strength of concrete, the stress-strain models proposed by Yang et al. and Hordijk were employed in compression and tension, respectively. From the conversion of these stress-strain models into rigidly perfect materials, the effectiveness factor for compression, ratio of effective tensile strength to compressive strength and angle of concrete friction were then mathematically generalized. The proposed shear friction strength model was compared with 91 push-off specimens compiled from the available literature. Unlike the existing equations or code equations, the proposed model possessed an application of diversity against various parameters. As a result, the mean and standard deviation of the ratios between experiments and predictions using the present model are 0.95 and 0.15, respectively, indicating a better accuracy and less variation than the other equations, regardless of concrete type, the amount of transverse reinforcement, and the magnitude of applied axial stresses.
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