• Journal of Preventive Medicine and Public Health
• /
• v.50 no.2
• /
• pp.83-90
• /
• 2017

Objectives: The aim of this study was to model the avoidable burden of the risk factors of road traffic crashes in Iran and to prioritize interventions to reduce that burden. Methods: The prevalence and the effect size of the risk factors were obtained from data documented by the traffic police of Iran in 2013. The effect size was estimated using an ordinal regression model. The potential impact fraction index was applied to calculate the avoidable burden in order to prioritize interventions. This index was calculated for theoretical, plausible, and feasible minimum risk level scenarios. The joint effects of the risk factors were then estimated for all the scenarios. Results: The highest avoidable burdens in the theoretical, plausible, and feasible minimum risk level scenarios for the non-use of child restraints on urban roads were 52.25, 28.63, and 46.67, respectively. In contrast, the value of this index for speeding was 76.24, 37.00, and 62.23, respectively, for rural roads. Conclusions: On the basis of the different scenarios considered in this research, we suggest focusing on future interventions to decrease the prevalence of speeding, the non-use of child restraints, the use of cell phones while driving, and helmet disuse, and the laws related to these items should be considered seriously.

• The Plant Pathology Journal
• /
• v.26 no.3
• /
• pp.216-222
• /
• 2010

Fusarium proliferatum is the causal agent of stalk and root rot disease of maize, foot rot disease of rice, basal and root rot disease of onion and knife cut disease of sugarcane in Iran. In recent years, incidence and severity of these diseases have been increased in Iran. Fifty seven F. proliferatum single-spore isolates collected from diseased maize, rice, onion and sugarcane plants at different areas were used to study genetic diversity by determination of vegetative compatibility groups (VCGs). Chlorate-resistant nitrate non-utilizing (nit) mutants were recovered from selected isolates of F. proliferatum and used in complementation tests. All isolates in which both nit1 and NitM (or nit3) mutants were recovered, demonstrated self-compatibility. Vegetative compatibility tests by pairing nit mutants identified 30 VCGs among 57 isolates. Twenty-three isolates belonged to singlemember VCGs and the remaining 34 isolates, belonged to other seven multimember VCGs. Segregation of F. proliferatum isolates obtained from various area and host plants into different VCGs in Iran is reported for the first time. In this study, none of isolates obtained from rice complemented with any other isolates from onion and sugarcane and, non complementation occurred between onion and sugarcane isolates. Also, only one complementation occurred between one isolate of maize and one isolate of sugarcane and rice. Thus, a correlation between VCGs grouping and host preferences was founded. It is concluded that natural populations of F. proliferatum in Iran are probably genetically divergent and include isolates representing a potential risk for disease development.

• Korean Journal of Ecology and Environment
• /
• v.37 no.4 s.109
• /
• pp.448-454
• /
• 2004

In order to evaluate the water quality (N, P and C) and the biological mass balance of semi-enclosed brackish Lake Obuchi, Japan, an ecosystem model was developed and applied to the lake, using the flow field calculated by a hydrodynamic model. The time series data of the observed tide level, river discharge and meteorological parameters from January 2001 to December 2002 were incorporated as the parameters of the hydrodynamic model. Water quality and biomass balance were estimated by the ecosystem model, and simulated fluctuations In water quality agreed with our observations. The carbon contents of POC, phytoplankton and zooplankton in the lake were calculated by the model at an average 7200, 1500 and 22 kg, respectively, which somewhat agreed with our observations of POC (5900 kg), phytoplankton (3800kg), and zooplankton (150kg).

• Journal of the Korean Society of Marine Environment & Safety
• /
• v.11 no.2 s.23
• /
• pp.65-71
• /
• 2005

This paper presents the maritime education and training at CMA. There are two kinds of Federal Maritime Academies, i.e. U. S. Merchant Marine Academy (USMMA) and U. S. Coast Guard Academy, which are supported by federal government and six State Maritime Academies operated by each state. CMA is a unique campus of the California State University(CSU). A specialized education combining classroom instruction, hands-on experience and professional development prepare students for a successful career in international business and logistics, maritime policy, engineering, technology or in the maritime and transportation industries. All students of CMA, under licensed faculty supervision, learn and train aboard the Training Ship Golden Bear during a two-month training cruise in their first year at CMA. Second-year students participate in a land-based cooperative, or sail on a commercial cruise or the Training Ship GOLDEN BEAR depending on their major. Third-year maritime licensing option students take a final cruise on the training ship, while other students participate in an additional land-based cooperative. In their senior year, students take license exams to complete graduation requirements.

• Journal of the Korean Society of Marine Environment & Safety
• /
• v.12 no.4 s.27
• /
• pp.285-291
• /
• 2006

In order to find the current structure between Sori Island and Yokji Island in the South Sea of Korea, water movements were measured in May, June, October and November of 2004 using ADCP(acoustic doppler current profiler). In the southwestern part of Yokji Island, northeastward flow in whole of depth was dominant by mean current The boundary layer between the upper layer and lower layer was formed between 15m and 20m and each layer different flow. The upper and lower layers have a different direction and speed of currents. In the calculated volume transport, the northeastward transport was greater than southwestward.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.17
• /
• pp.7997-8002
• /
• 2015

Gene amplification is an important mechanism in the development and progression of cancer. Currently, gene amplification status is generally determined by in situ hybridization (ISH). Multiplex ligation-dependent probe amplification (MLPA) is a PCR-based method that allows copy number detection of up to 50 nucleic acid sequences in one reaction. The aim of the present study was to compare results for HER2, CCND1, MYC and ESR1 gene amplification detected by MLPA with fluorescent in situ hybridization (FISH) and chromogenic in situ hybridization (CISH) as clinically approved methods. Tissue samples of 170 invasive breast cancers were collected. All were ER positive. Tissue samples had previously been tested for HER2 using immunohistochemistry. Amplification of the selected genes were assessed using MLPA, FISH and CISH and results were compared. HER2 MLPA and ISH results were also compared with HER2 immunohistochemistry (IHC) which detects protein overexpression. Amplification of HER2, CCND1, MYC and ESR1 by MLPA were found in 9%, 19%, 20% and 2% of samples, respectively. Amplification of HER2, CCND1, MYC and ESR1 by FISH was noted in 7%, 16%, 16% and 1% of samples, respectively. A high level of concordance was found between MLPA/FISH (HER2: 88%, CCND1: 88%, MYC: 86%, ESR1: 92%) and MLPA/CISH (HER2: 84%). Of all IHC 3+ cases, 91% were amplified by MLPA. In IHC 2+ group, 31% were MLPA amplified. In IHC 1+ group, 2% were MLPA amplified. None of the IHC 0 cases were amplified by MLPA. Our results indicate that there is a good correlation between MLPA, IHC and ISH results. Therefore, MLPA can serve as an alternative to ISH for detection of gene amplification.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.15
• /
• pp.6327-6330
• /
• 2015

Background: Glioblastoma is a highly aggressive and malignant brain tumor. Risk factors are largely unknown however, although several biomarkers have been identified which may support development, angiogenesis and invasion of tumor cells. One of these biomarkers is PAI-1.4G/5G and A-844G are two common polymorphisms in the gene promotor of PAI 1 that may be related to high transcription and expression of this gene. Studies have shown that the prevalence of the 4G and 844G allele is significantly higher in patients with some cancers and genetic disorders. Materials and Methods: We here assessed the association of 4G/5G and A-844G polymorphisms with glioblastoma cancer risk in Iranians in a case-control study. All 71 patients with clinically confirmed and 140 volunteers with no history and symptoms of glioblastoma as control group were screened for 4G/5G and A-844G polymorphisms of PAI-1, using ARMS-PCR. Genotype and allele frequencies of case and control groups were analyzed using the DeFinetti program. Results: Our results showed significant associations between 4G/5G (p=0.01824) and A-844G (p = 0.02012) polymorphisms of the PAI-1 gene with glioblastoma cancer risk in our Iranian population. Conclusions: The results of this study supporting an association of the PAI-1 4G/5G (p=0.01824) and A-844G (p = 0.02012) polymorphisms with increasing glioblastoma cancer risk in Iranian patients.

• Journal of architectural history
• /
• v.17 no.4
• /
• pp.129-152
• /
• 2008

Early Buddhist rock cave temples of India, in spite of being an origin of Buddhist temples, has little been studied in Korea. After field studies and an interpretation of their forms in conjunction with religious life, precedent theories are supplemented and refuted as follows. Starting from the 2nd century B,C., Buddhist ascetic disciples digged residential rock caves, called vihara, for protection from monsoon rain and hot weather, A typical arrangement was settled -a courtyard type, with 3 side rows of tiny one-person bedroom and a front veranda with columns. Also digged were Chaitya caves, in line with viharas, to worship, which is the tumulus of Buddha's relics. I suggest that the original type of chaitya a simple circle cave with a stupa, suitable for circumambulating ceremonies. I refute the existing theory presenting Barabar caves of Ajivika as a chaitya origin, featuring empty circular room without a stupa. I also interpret a typical apsidal plan as being a simple result of adding a place of worshipping rites in front of the stupa. Enclosing columns around a cylindrical stupa is a result of reinforcing both the divine space and circumambulating ceremonies, with elongation toward hall. Finally the chaitya came to have a grandeur apsidal plan with high vault ceiling nave and a side aisle as in Western cathedrals with large frontal horseshoe arch windows. The Buddha image, which had become a new worshipping object, was integrated into the stupa and interior surface. First the stupa and then the statue was introduced to residential Viharas. Therefore, I suggest that the vihara should be renamed as 'chaitya' as a worshipping place, by establishing statue rooms without bedrooms at all. The functionally changed vihara is similar in form to a 'rectangular type of chaitya', little known and developed in different routes. A columned inner courtyard gradually becama an offering place, like Hindu mandapa, Buddhist caves ware changed to a kind of Tantric and Hindu temple by means of statue worshipping offering rituals.

• Journal of the Korea Society of Computer and Information
• /
• v.16 no.12
• /
• pp.49-57
• /
• 2011

Extraction of regions of interest (ROIs) is the first and important step for the applications in computer vision and affects the rest of the application process. However, ROI extraction can be easily affected by the environment such as illumination, camera, etc. Many applications adopt problem-specific knowledge and/or post-processing to correct the error occurred in ROI extraction. In this paper, proposed is a robust framework that could overcome the environmental change and is independent from the rest of the process. The proposed framework uses a differential image and a color distribution to extract ROIs. The color distribution can be learned on-line, which make the framework to be robust to environmental change. Even more, the components of the framework are independent each other, which makes the framework flexible and extensible. The usefulness of the proposed framework is demonstrated with the application of hand region extraction in an image sequence.

• Korean Journal of Plant Resources
• /
• v.30 no.5
• /
• pp.535-541
• /
• 2017

In this study, methanol (CAMe) and ethanol (CAEt) extract of Theobroma cacao L. were tested to see possibility as natural functional cosmetic agent. Cacao extract and cacao extract loaded gel were evaluated for various properties such as antioxidant, antimicrobial, cell viability, anti-inflammatory. Inhibition of nitric oxide production in lipopolysaccaride (LPS) stimulated raw 264.7cells, at concentration of $0.125{\sim}1{\mu}g/ml$ a dose-dependent manner. Gel formulation (3% extract) were stable for 60day in both extract. In conclusion, gel containing extract of Theobroma cacao L. indicated strong possibility for functional cosmetic ingredient.