• Proceedings of the Korean Institute of Intelligent Systems Conference
• /
• 1998.06a
• /
• pp.725-730
• /
• 1998

Recently we extended the fuzzy model for rule based systems incorporating an importance factor for each rule. The model permits for both unrestricted as well as non-negative importance factors. We use this extended model to design a fuzzy rule based classifier system which uses both the firing strength of the rule and the importance factor to decide the class label. The effectiveness of the scheme is established using several data sets.

• Journal of the Korean Data and Information Science Society
• /
• v.17 no.4
• /
• pp.1169-1180
• /
• 2006

Partial least squares regression (PLS) is a biased, non-least squares regression method and is an alternative to the ordinary least squares regression (OLS) when predictors are highly collinear or predictors outnumber observations. One way to understand the properties of biased regression methods is to know how the estimators shrink the OLS estimator. In this paper, we introduce an expression for the shrinkage factor of PLS and develop a new shrinkage expression, and then prove the equivalence of the two representations. We use two near-infrared (NIR) data sets to show general behavior of the shrinkage and in particular for what eigendirections PLS expands the OLS coefficients.

• Korean Journal of Clinical Pharmacy
• /
• v.28 no.2
• /
• pp.88-94
• /
• 2018

Background: We strived to evaluate the status of nivolumab use and associated factors on the clinical efficacy of the drug. Methods: The study was retrospectively conducted in patients who had been administered nivolumab at least once at the cancer center of Seoul National University Hospital from June 2015 to April 2017. Data were collected from electronic medical records. A medication-use evaluation was performed based on the American Society of Health-System Pharmacists mediation-use guidelines. Results: Sixty-six of the 74 patients (89.2%) showed indications approved for nivolumab use by the Korean Ministry of Food and Drug Safety (MFDS; n=55) or the US Food and Drug Administration (FDA; n=11). Approximately 73.0% of the patients were administered the approved dose of 3 mg/kg but 25.7% were administered an unapproved fixed dose of 100 mg. The overall response rate was 21.7%, and the response rate of non-small cell lung cancer patients, who accounted for the largest number of indications, was 18.8%. Adverse reactions were found in 90.1% of the patients and were mostly mild (86%). The expression of programmed death-ligand 1 (PD-L1) was analyzed as a factor affecting treatment response (p=0.028, odds ratio [OR]=11.331). Conclusion: PD-L1 expression was found to affect treatment response. However, caution is required while using an unapproved dosage and in the absence of monitoring for effectiveness and safety. Therefore, an effective protocol or instruction manual for the proper use of nivolumab should be considered.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.9
• /
• pp.3685-3690
• /
• 2015

Background: Low-dose oral contraceptives (OC) were approved by the Japanese Ministry of Health, Labor and Welfare in 1999, yet despite their contraceptive and non-contraceptive health benefits, only 5% of the target population use them. Fear of increased cancer risk, particularly breast cancer, is one reason for this. Due to low OC uptake and low screening participation, a paucity of data is available on the risk of OC use and breast cancer in Japanese women. The present study investigated OC use and breast cancer risk, as well as menstrual, reproductive and family factors. Materials and Methods: This was a clinic-based case-control study of women aged 20-69yrs who had undergone breast screening between January 2007 and December 2013 in central Tokyo. In all, 28.8% of the participants had experience with OC use. Cases were 155 women with a pathologically confirmed diagnosis of breast cancer. Controls were the remaining 12,333 women. Results: Increased age was a significant risk factor for breast cancer (p<0.001). A lower risk was found in premenopausal women presently taking OC compared to never users (OR 0.45; 95% CI 0.22-0.90) after adjusting for age, parity and breast feeding, and a family history of breast cancer. Conclusions: Increased age rather than OC use had a greater effect on breast cancer risk. This risk may be decreased in premenopausal women with OC use, but further long-term prospective studies are necessary.

• Journal of The Korean Association of Information Education
• /
• v.26 no.6
• /
• pp.533-541
• /
• 2022

Metaverse have begun to attract attention because it facilitate interaction between learners and teachers in non face- to- face environment. In order to use the metaverse in the educational field such as online class, it is important that pre-service teachers intend to use it. The purpose of this study is to analyze the structural relationship between the pre-service teacher's educational competence and the intention to use the metaverse based on the technology acceptance model. The influence factors of flexibility for new technology, teacher efficacy, and TPACK were examined. It was conducted with 240 pre-service teachers, and the data of 183 pre-service teachers finally collected were used for the analysis. As a result of the study, among the metaverse educational competencies of elementary school pre-service teachers, flexibility and TPACK mediate perceived ease, and the pathways affecting metaverse use intention were significant. In this regard, theoretical and practical implications that can be helpful in the discussion and intention of using the metaverse of pre-service teachers were presented.

• International Journal of Knowledge Content Development & Technology
• /
• v.7 no.4
• /
• pp.51-69
• /
• 2017

Availability, awareness and use of electronic resources provide access to authoritative, reliable, accurate and timely access to information. The use of electronic information resources (EIRs) can enable innovation in teaching and increase timeliness in research of postgraduate students which will eventual result into encouragement of the expected research-led enquiry in this digital age. The study adopted a descriptive survey design. Samples of 300 of postgraduate students within seven out 13 Faculties were randomly selected. Data were collected using questionnaire designed to elicit response from respondents and data were analyzed using descriptive statistics methods percentages, mean, and standard deviation. Results indicated that internet was ranked most available and used in the university. Low level of usage of electronic resources, in particular, full texts data bases is linked to a number of constraints: Interrupted power supply was ranked highest among other factors as speed and capacity of computers, retrieval of records with high recall and low precision, retrieving records relevant to information need, lack of knowledge of search techniques to retrieve information effectively, non possession of requisite IT skills and problems accessing the internet. The study recommended that usage of electronic resources be made compulsory, intensifying awareness campaigns concerning the availability, training on use of electronic resources and the problem of power outage be addressed.

• Journal of the Korean Institute of Educational Facilities
• /
• v.14 no.3
• /
• pp.36-46
• /
• 2007

This study is based on the need to reform mixed use plan of school facilities considering the characteristics of depressed downtown area. It started with the object to make a plan by deducting function of place required and corresponded to the characteristics of depressed downtown area in Pohang city. As the result of researching present status and the characteristics of six elementary schools in Pohang which the number of student has decreased, it is found that they are required to have change in the region of depressed downtown area which have fallen behind and obsolete school facilities which idle classrooms have increased and to have reformations of a city are characterized by 5 types as poor life environment, lack of cultural facilities as community institution, poor open-space and ecological environment, non-activation of conventional market and contraction of commerce industry by outflow of industry, transfer of administration operation function and etc. and the region of school under researching shows these characteristics. I planed the mixed use program with factors of local community facility, status of school facility use and depressed area's characteristics. Finally, I propose the mixed use plan of school facilities as the strong point of sustainable development which influences on and be influenced by regional characteristics and structure of city.

• Journal of East-West Nursing Research
• /
• v.17 no.2
• /
• pp.156-163
• /
• 2011

Purpose: The purpose of this study was to examine the influences of stress, loneliness, self-control on the addiction of cell phone use among university students. Methods: Data were collected through questionnaires from 467 students and were analyzed using descriptive statistics, t-test, ANOVA, Scheffe's test, Pearson's correlation coefficients and Stepwise multiple regression analysis with SPSS/WIN 19.0 program. Results: Out of the subjects, 1.5% were found to be addiction group, 89.9% at potential risk group, and 8.6% at non-addiction group. Addiction of cell phone use was significantly correlated with stress, loneliness and self-control. The influential factors affecting addiction of cell phone use over use problem, self-control, health problem, main using method and stress, which explained about 25.6% of the variance. Conclusion: The results of this study indicate that nursing intervention are needed to improve addiction of cell phone use, and that such variables should be carefully considered in intervention for university students.

• The Journal of Information Systems
• /
• v.27 no.4
• /
• pp.97-114
• /
• 2018

Purpose Compliance support system (CSS) aims to support employees' voluntary compliance activities, however, it requires a different approach from the acceptance of other general information systems. In other words, the user's concern that his/her compliance activities recorded in the system are monitored may hinder the active use of the system. In this regard, we set up a research model to investigate the factors that affect the intention to use CSS, by including perceived usefulness, compliance commitment, and surveillance concern. Design/methodology/approach A questionnaire survey was conducted for the employees of a domestic oil-company, who operates their own CSS. Based on the 865 data collected, a structural model analysis using PLS was conducted. As a result, all four hypotheses were accepted. It was found that perceived usefulness of CSS has a positive effect on the intention to use CSS. Compliance commitment has a positive effect both on perceived usefulness and intention to use CSS. In contrast, surveillance concern of one's non-compliance recorded in the CSS was shown to have a negative effect on the relationship between compliance commitment and perceived usefulness. Findings This study has academic implications in that it extends the viewpoint of the existing technology acceptance mechanism by examining the two aspects, i.e., compliance commitment and surveillance concern. This study may also provide practical directions to strengthen the use of the active compliance support system by the employees.

• The Journal of the Korea Contents Association
• /
• v.20 no.10
• /
• pp.436-448
• /
• 2020

This study aims to determine the effect of e-cigarettes on oral health by investigating the association between the use of different tobacco products and oral health among Korean adults aged 19 years and older. Data from the 2017 Community Health Survey were used for the study. Respondents were divided into four groups: non-smokers, cigarette smokers, e-cigarette smokers, and users of both products. A sample of 228,357 respondents was selected for analysis. Twenty-four questionnaires with missing values (non-response or refusal) were excluded from the sample. A regression analysis was performed with oral as the dependent variable. A multivariate regression analysis showed a significant difference between cigarette smokers and users of both products when compared to the non-smokers. However, e-cigarette users showed a significant when the variables were correlated with age and gender. There was no significant difference in other dependent variables in a multivariate regression analysis. The results of the study indicated no association between e-cigarette use and oral health. More research is needed on factors such as amount and intensity of e-cigarette use.