• KIPS Transactions on Computer and Communication Systems
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• v.10 no.3
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• pp.81-92
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• 2021

As the aging population of Korean agriculture and rural areas and the decline of the agricultural population are gradually deepening, the influx of population through returning to farming and rural areas is urgently needed. To this end, the most important problems to be solved were the lack of information that would help those who want to return to farming or rural areas when making decisions. Therefore, a survey was conducted for AHP analysis on related experts to find out the information (decision factors) required when selecting a return-to-farm or return-to-country migration area through this study. The AHP analysis showed that "Economic factors" were the most important among the three items in the primary class, while "Housing and land prices", "Metropolitan accessibility and traffic" and "Residential information" were the most important in the secondary class. The results of these studies are reflected in the information system to systematically support the decision-making of those who wish to return to farming or rural areas.It is hoped that it will be indirectly helpful and ultimately contribute to the revitalization and development of Korean agriculture and rural areas, which are aging.

• Journal of the Society of Disaster Information
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• v.16 no.3
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• pp.479-492
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• 2020

Purpose: The purpose of this study is to analyze the impact of regional characteristics on population movement on the Seoul metropolitan areas. Method: To this end, 66 basic entities in the Seoul metropolitan area were divided into three regions by analyzing the demographic movement data from 2010 to 2016 and the factors for determining population movement within and between regions were identified by applying a stepwise regression technique. Result: The major analysis confirmed that the increase in the number of apartments in all areas of the Seoul metropolitan area, the increase in the number of single-family homes, the increase in the number of employees, the increase in manufacturers, the growth rate of knowledge, culture, and leisure industries, the increase rate of GRDP, and the opening of new subway stations. In particular, the growth rate of the number of apartments, the growth rate of the knowledge, culture and leisure industries, the increase rate of GRDP, and the opening of new subway stations played a positive role in increasing population inflow. Conclusion: The result showed that by region, the growth rate of knowledge, culture and leisure industries contributed greatly to the inflow of population in the first region, and that the opening of new subway stations and the increase of GRDPs were the main factors. The increase in the number of apartments and subway stations were the main factors in the three areas.

• Molecules and Cells
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• v.44 no.9
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• pp.658-669
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• 2021

Enhancers have been conventionally perceived as cis-acting elements that provide binding sites for trans-acting factors. However, recent studies have shown that enhancers are transcribed and that these transcripts, called enhancer RNAs (eRNAs), have a regulatory function. Here, we identified putative eRNAs by profiling and determining the overlap between noncoding RNA expression loci and eRNA-associated histone marks such as H3K27ac and H3K4me1 in hepatocellular carcinoma (HCC) cell lines. Of the 132 HCC-derived noncoding RNAs, 74 overlapped with the eRNA loci defined by the FANTOM consortium, and 65 were located in the proximal regions of genes differentially expressed between normal and tumor tissues in TCGA dataset. Interestingly, knockdown of two selected putative eRNAs, THUMPD3-AS1 and LINC01572, led to downregulation of their target mRNAs and to a reduction in the proliferation and migration of HCC cells. Additionally, the expression of these two noncoding RNAs and target mRNAs was elevated in tumor samples in the TCGA dataset, and high expression was associated with poor survival of patients. Collectively, our study suggests that noncoding RNAs such as THUMPD3-AS1 and LINC01572 (i.e., putative eRNAs) can promote the transcription of genes involved in cell proliferation and differentiation and that the dysregulation of these noncoding RNAs can cause cancers such as HCC.