• Analytical Science and Technology
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• v.20 no.5
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• pp.370-382
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• 2007

In this study, solid-phase microextraction (SPME) technique using GC/FID was studied as a possible alternative to liquid-liquid extraction for the analysis of EGBE, DGBE, DBM and TGME in water, and an optimization condition of trace analysis of EGBE, DGBE, DBM and TGME using the factorial design was described. Experiments used a fractional factorial design method followed by central composite design allowing optimization of a number of factors as well as statical analysis of results. The response surface analysis showed that the extraction efficiency can be described by a second-order polynomial equation in which the salts concentration, extraction temperature, extraction time and sonication time are the major influences. Using DOE, a new data-dependent method was developed that improved the quantity of confidently analyzed EGBE, DGBE, DBM and TGME in water samples.

• YAKHAK HOEJI
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• v.42 no.6
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• pp.545-551
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• 1998

Near Infrared transmittance Spectroscopy (NIRS) was used to evaluate and quantify the pharmaceutical active compounds. In the paper, taurine (2-Aminoethanesulfonic acid) was quantitatively analyzed in commercial pharmaceutical preparations. For calibration a central composite factorial design was used to determine concentrations of ingredients in reference samples. For the quantitative analysis of taurine, the most suitable data analysis method includes the calculation of second derivatives and a partial least squares regression (PLSR) model. By NIR spectrometry, combined with PLSR, the taurine concentration was successfully predicted with a relative standard error of prediction (SEP) lower than 1.04%.

• Nuclear Engineering and Technology
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• v.33 no.6
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• pp.605-618
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• 2001

For the mechanical stability assessment of a deep underground high-level waste repository. computer simulations using FLAC3D were carried out and important parameters including stress ratio, depth, tunnel size, joint spacing, and joint properties were chosen from sensitivity analysis. The main effect as well as the interaction effect between the important parameters could be investigated effectively using fractional factorial design . In order to analyze the stability of the disposal tunnel and deposition hole in a discontinuous rock mass, different modelings were performed under different conditions using 3DEC and the influence of joint distribution and properties, rock properties and stress ratio could be determined. From the three dimensional modelings, it was concluded that the conceptual repository design was mechanically stable even in a discontinuous rock mass.

• Journal of Korean Tunnelling and Underground Space Association
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• v.16 no.1
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• pp.91-104
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• 2014

An Excavation Damaged Zone (EDZ), in which rock properties are permanently changed due to blasting impact or stress redistribution, can influence the behavior and stability of structures. In this study, the mechanical stability of an underground opening was simulated by using FLAC, which is a two-dimensional modeling code, with a consideration of EDZ. A sensitivity analysis was also carried out with fractional factorial design. From the modeling, it was found that the behavior and the stability of an underground tunnel are strongly dependent on the existence of the EDZ. The sensitivity analysis showed that the key parameters affecting the factor of safety around the tunnel are in-situ stress ratio, depth, cohesion, reduction ratio, internal friction angle, and height and width of the tunnel. It is necessary to consider the EDZ, which can significantly affect mechanical stability in tunnel design.

• The Korean Journal of Pain
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• v.34 no.4
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• pp.501-508
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• 2021

Background: Yellow flags are psychosocial factors shown to be indicative of long-term chronicity and disability. The purpose of the study was to evaluate the psychometric properties of the Turkish Yellow Flag Questionnaire (YFQ) in patients with chronic musculoskeletal pain (CMP). Methods: The cross-cultural adaptation was conducted with translation and back-translation of the original version. Reliability (internal consistency and test-retest) was examined for 231 patients with CMP. Construct validity was assessed by correlating the YFQ with the Hospital Anxiety and Depression Scale (HADS), Orebro Musculoskeletal Pain Questionnaire (OMPQ), and Tampa Kinesiophobia Scale (TKS). Factorial validity was examined with both exploratory and confirmatory factorial analysis. Results: The YFQ showed excellent test/retest reliability with an Intraclass correlation coefficient of 0.82. The internal consistency was moderate (Cronbach's alpha of 0.797). As a result of the exploratory factor analysis, there were 7 domains compatible with the original version. As a result of confirmatory factor analysis, the seven-factor structure of YFQ was confirmed. There was a statistically significant correlation between YFQ-total score and OMPQ (r = 0.57, P < 0.001), HADS-anxiety (r = 0.32, P < 0.001), HADS-depression (r = 0.44, P < 0.001), and TKS (r = 0.37, P < 0.001). Conclusions: This study's results provide considerable evidence that the Turkish version of the YFQ has appropriate psychometric properties, including test-retest reliability, internal consistency, construct validity and factorial validity. It can be used for evaluating psychosocial impact in patients with CMP.

• Geomechanics and Engineering
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• v.2 no.2
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• pp.71-88
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• 2010

Soil nailing technique is being widely used for stabilization of vertical cuts because of its economic, environment friendly and speedy construction. Global stability and lateral displacement are the two important stability criteria for the soil nail walls. The primary objective of the present study is to evaluate soil nail wall stability criteria under the influence of in-situ soil variability. Finite element based numerical experiments are performed in accordance with the methodology of $2^3$ factorial design of experiments. Based on the analysis of the observations from numerical experiments, two regression models are developed, and used for reliability analyses of global stability and lateral displacement of the soil nail wall. A 10 m high prototype soil nail wall is considered for better understanding and to highlight the practical implications of the present study. Based on the study, lateral displacements beyond 0.10% of vertical wall height and variability of in-situ soil parameters are found to be critical from the stability criteria considerations of the soil nail wall.

• Journal of the Korean Society for Precision Engineering
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• v.26 no.3
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• pp.47-54
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• 2009

In the manufacturing industry, there has been a significant increase in the use of coordinate measuring machines(CMM). In this paper, the sources of CMM measurement performance are discussed. The effects of workpiece position, length and orientation are analyzed by using the design of experiments. Both a fractional factorial design and a factorial design are employed to conduct the experimental study. The analysis of variance is performed to determine the significance of factors in the experiment and regression analysis is applied to make the measurement approximate model. The results show that position along the Z axis, length and orientation affect the CMM measurement performance.

• Journal of Korean Society for Quality Management
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• v.40 no.1
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• pp.15-24
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• 2012

For the construction of fractional factorial designs, the various arrays can be widely used. In this paper we review the statistical properties of fractional designs constructed by two arrays such as orthogonal array and partially balanced array, and develop a quick and easy method for analyzing unreplicated saturated designs. The proposed method can be characterized that we control the error rate by experiment-wise way and exploit the multivariate Student $t$-distribution. Especially the proposed method can be used efficiently together with some exploratory analysis methods, such as half normal probability plot method.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2000.11a
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• pp.862-865
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• 2000

The object of this paper is to evaluate the surface roughness using the experimental equation of surface roughness, which is developed in turning by an orthogonal array method. $L_9{3^4}$ orthogonal array method, one of fractional factorial design has been used to study effects of main cutting parameters such as cutting speed, feed rate and depth of cut, on the surface roughness. And the analysis of variance (ANOVA)-test has been used to check the significance of cutting parameters. Using the result of ANOVA-test, the experimental equation of surface roughness, which consists of only significant cutting parameter - feed rate, has been developed. The coefficient of determination of this equation is 0.962.

• Journal of the Semiconductor & Display Technology
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• v.12 no.4
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• pp.9-13
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• 2013

Lapping is a very complicated and random process resulting from the variation of abrasive grains in its sizes and shapes and from the numerous factors having an effect on the process quality. This paper presents a study of a $2^4$ full factorial experimental design and analysis to optimize surface quality in lapping operation. The optimization of the factors to obtain minimum surface roughness was carried out by incorporating effect plots, main effect plots, interaction plots, analysis of variance(ANOVA), surface plots, and contour plots. The statistical design experiments, designed to reduce the total number of experiments required, indicated that, within the selected conditions, all the parameters influenced at a significance level of 5%. In addition, some of the possible interactions between these parameters also influenced the lapping process, especially those that were of third order. A regression model was suggested and fitted the experimental data very well.