• Title/Summary/Keyword: FP

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Prospective Randomized Trial for Postoperative Adjuvant Chemotherapy in Gastric Cancer Patients without Serosal Invasion -Preliminary Report- (장막 침윤이 없는 위암 환자에서 수술 후 보조적 화학 요법에 대한 전향적 연구 -중간 보고-)

  • Kim Yong-Ho;Kim Byung-Sik;Lee Chang-Hwan;Kim Wan Su;Yook Jung-Whan;Oh Sung-Tae;Park Kun-Choon
    • Journal of Gastric Cancer
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    • v.1 no.4
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    • pp.221-227
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    • 2001
  • Purpose: We have carried out prospective randomized clinical trial to compare survival benefit and side effect among three postoperative adjuvant chemotherapeutic regimens in serosa-negative gastric cancer patients. Materials and Methods: Total 317 cases were recognized as serosa negative and randomized into three groups at operating room. Out of them, 172 cases were excluded because of various reasons and 135 cases were analyzed finally; Group A 36 cases, Group B 49 cases, Group C 50 cases. Group A were treated with intravenous FP combination therapy, group B with MF combination therapy and group C with oral $UFT^{(R)}$ (mixture of Tegafur and Uracil) for one year. The median follow-up period was 30 months. Results: $88.9\%$ of Group A, $83.7\%$ of Group B and $90.4\%$ of Group C received adequate chemotherapy. The complication rates of Group A ($44.4\%$) was significantly higher than group B ($20.4\%$) and group C ($24.0\%$)(P<0.05). Most frequent complications were nausea and vomiting. The 3-year survival rates and disease-free survival rates were $92.2\%$ and $89.9\%$ respectively (Group A: $96.6\%,\;87.8\%$, B: $90.3\%,\;87.7\%$, C: $95.7\%,\;93.8\%$). There were no significant differences in survival rate and disease-free survival rate among the three groups (P>0.05). Conclusion: This study might suggest that the survival benefit of postoperative adjuvant chemotherapy for gastric Pseudomonas aeruginosa, and therefore it may be a useful adjunct tool for detection of Pseudomonas aeruginosa infection in combination with other conventional techniques.

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A Study on the Practice Variations According to Physician Characteristics (의사 특성에 따른 외래 진료내용의 변이)

  • Jeong, Eun-Kyeong;Moon, Ok-Ryun;Kim, Chang-Yup
    • Journal of Preventive Medicine and Public Health
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    • v.26 no.4 s.44
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    • pp.614-627
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    • 1993
  • It is well known that a physician's personal characteristic affects his practice pattern. Furthermore, a physician's specialty has powerful influences on his practice pattern. However, despite the fact that specialization has received the most attention for its influence on physician's service behavior, few studies have been conducted on the variations of contents and volume of physician's services. This study has intended to identify factors influencing the practice variations according to various physician characteristics. There are some other evidences that medical care providers are different in using of health services and resources in Korea. Four physician characteristics were selected for the analysis, two demographical factors, age and sex, and two practice factors, place of practice and medical specialty. Also, three indicators of service amount (total amount of insurance claim bill, number of visits per case, number of prescriptions per case) were selected. From the pool of insurance claims for ambulatory care received by the Korean National Federation of Medical Insurance(NFMI), 84,898 cases were randomly sampled. In the meantime using physician database of NFMI, 613 general practitioners (GP), 107 regular family physicians (FP), 483 'grandfather' family physicians(GFP), and 1,157 specialist practitioners(SP) were randomly sampled. Their different practice contents were compared concerning the specialty, age groups, sex, and practice sites (urban-rural) Specialist physicians tend to provide more costly care than do generalists. General practitioners and family physicians usually make fewer following visits and prescriptions. Age is also the important factor in determining the amount of services, which is highest at the physician's age group of 40's. Female doctors and urban practitioners use much more resources than their counterparts respectively. Research findings suggest that physician's characteristics particularly the specialty can affect practice patterns and resource utilizations. Other characteristics such as age and sex are not controllable but physician's specialty is relatively easily controllable during the entire phases of policy implementation. This is all the more true in the individual's initial decision of his specialty. Specialization therefore should receive policymaker's attention for its potential influence on medical care utilization and health care expenditure.

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A Text Mining-based Intrusion Log Recommendation in Digital Forensics (디지털 포렌식에서 텍스트 마이닝 기반 침입 흔적 로그 추천)

  • Ko, Sujeong
    • KIPS Transactions on Computer and Communication Systems
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    • v.2 no.6
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    • pp.279-290
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    • 2013
  • In digital forensics log files have been stored as a form of large data for the purpose of tracing users' past behaviors. It is difficult for investigators to manually analysis the large log data without clues. In this paper, we propose a text mining technique for extracting intrusion logs from a large log set to recommend reliable evidences to investigators. In the training stage, the proposed method extracts intrusion association words from a training log set by using Apriori algorithm after preprocessing and the probability of intrusion for association words are computed by combining support and confidence. Robinson's method of computing confidences for filtering spam mails is applied to extracting intrusion logs in the proposed method. As the results, the association word knowledge base is constructed by including the weights of the probability of intrusion for association words to improve the accuracy. In the test stage, the probability of intrusion logs and the probability of normal logs in a test log set are computed by Fisher's inverse chi-square classification algorithm based on the association word knowledge base respectively and intrusion logs are extracted from combining the results. Then, the intrusion logs are recommended to investigators. The proposed method uses a training method of clearly analyzing the meaning of data from an unstructured large log data. As the results, it complements the problem of reduction in accuracy caused by data ambiguity. In addition, the proposed method recommends intrusion logs by using Fisher's inverse chi-square classification algorithm. So, it reduces the rate of false positive(FP) and decreases in laborious effort to extract evidences manually.

EU FP6 Welfare Quality® Poultry Assessment Systems

  • Butterworth, A.
    • Korean Journal of Poultry Science
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    • v.36 no.3
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    • pp.239-246
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    • 2009
  • Animal welfare is of considerable importance to European consumers and citizens, this being most recently confirmed in EU barometer studies. Researchers and others have long proposed that animal-based measures (measures taken on animals, e.g. their health and behaviour) can provide a valid indicator of animal welfare; since welfare is a characteristic of the individual animal. Therefore, a welfare assessment can be essentially based on animal-based measures, but with use of resource measures to provide the capacity to assess 'risk factors'. The first goal of this project was to develop a welfare monitoring system that enables assessment of welfare status through standardised conversion of welfare measures into accessible and understandable information. The acquired information on one hand provides feedback to animal unit managers about the welfare status of their animals, and on the other, information on the welfare status of animal-related products for consumers and retailers. The second goal of Welfare $Quality^{(R)}$ was to improve animal welfare by minimising the occurrence of harmful behavioural and physiological states, improving human-animal relationships, and providing animals with safe and stimulating environments. The different measurable aspects of welfare to be covered are turned into welfare criteria. The criteria reflect what is meaningful to animals as understood by animal welfare science. Once all the measures have been performed on an animal unit, a bottom-up approach is followed to produce an overall assessment of animal welfare on that particular unit: first the data collected (i.e. values obtained for the different measures on the animal unit) are combined to calculate criterion-scores; then criterion-scores are combined to calculate principle-scores; and finally the animal unit is assigned to a welfare category according to the principle-scores it obtained.

A Study on the Quantitative Process Facility Standards that Require H2S Toxic Gas Detectors and Location Selection for Emergency Safety (H2S 독성가스감지기가 필요한 정량적 공정설비 기준 및 비상시 안전을 위한 위치선정 방안에 대한 연구)

  • Choi, Jae-Young;Kwon, Jung-Hwan
    • Journal of the Korean Institute of Gas
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    • v.22 no.2
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    • pp.90-96
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    • 2018
  • Design techniques for minimizing the damage caused by leakage of $H_2S$ gas, contained in natural gas and petroleum, have been widely studied abroad in chemical plants that purify and process natural gas and petroleum. However, there is no domestic engineering practice and regulation of $H_2S$. In accordance with the circumstances, this study proposes the quantitative criteria of process equipment to install $H_2S$ toxic gas detector as 500 ppm and explains the valid basis. The $H_2S$ gas dispersion radius up to IDLH 100 ppm is calculated by ALOHA under previous $H_2S$ gas leak accident scenario. The weather conditions of modeling include the conditions of Ulsan, Yeosu and Daesan, the three major petrochemical complexes in Korea. The long radius up to 100 ppm was derived in order of Ulsan, Daesan, Yeosu. For emergency safety the dispersion radius up to 100 ppm of the $H_2S$ gas obtained in this study should be extended to apply the additional $H_2S$ toxic gas detector, and local climate conditions should be considered.

Interactive Projection by Closed-loop based Position Tracking of Projected Area for Portable Projector (이동 프로젝터 투사영역의 폐회로 기반 위치추적에 의한 인터랙티브 투사)

  • Park, Ji-Young;Rhee, Seon-Min;Kim, Myoung-Hee
    • Journal of KIISE:Software and Applications
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    • v.37 no.1
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    • pp.29-38
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    • 2010
  • We propose an interactive projection technique to display details of a large image in a high resolution and brightness by tracking a portable projector. A closed-loop based tracking method is presented to update the projected image while a user changes the position of the detail area by moving the portable projector. A marker is embedded in the large image to indicate the position to be occupied by the detail image projected by the portable projector. The marker is extracted in sequential images acquired by a camera attached to the portable projector. The marker position in the large display image is updated under a constraint that the center positions of marker and camera frame coincide in every camera frame. The image and projective transformation for warping are calculated using the marker position and shape in the camera frame. The marker's four corner points are determined by a four-step segmentation process which consists of camera image preprocessing based on HSI, edge extraction by Hough transformation, quadrangle test, and cross-ratio test. The interactive projection system implemented by the proposed method performs at about 24fps. In the user study, the overall feedback about the system usability was very high.

A Small-area Hardware Implementation of EGML-based Moving Object Detection Processor (EGML 기반 이동객체 검출 프로세서의 저면적 하드웨어 구현)

  • Sung, Mi-ji;Shin, Kyung-wook
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.21 no.12
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    • pp.2213-2220
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    • 2017
  • This paper proposes an efficient approach for hardware implementation of moving object detection (MOD) processor using effective Gaussian mixture learning (EGML)-based background subtraction method. Arithmetic units used in background generation were implemented using LUT-based approximation to reduce hardware complexity. Hardware resources used for both background subtraction and Gaussian probability density calculation were shared. The MOD processor was verified by FPGA-in-the-loop simulation using MATLAB/Simulink. The MOD performance was evaluated by using six types of video defined in IEEE CDW-2014 dataset, which resulted the average of recall value of 0.7700, the average of precision value of 0.7170, and the average of F-measure value of 0.7293. The MOD processor was implemented with 882 slices and block RAM of $146{\times}36kbits$ on Virtex5 FPGA, resulting in 60% hardware reduction compared to conventional design based on EGML. It was estimated that the MOD processor could operate with 75 MHz clock, resulting in real-time processing of $800{\times}600$ video with a frame rate of 39 fps.

Multi-view Generation using High Resolution Stereoscopic Cameras and a Low Resolution Time-of-Flight Camera (고해상도 스테레오 카메라와 저해상도 깊이 카메라를 이용한 다시점 영상 생성)

  • Lee, Cheon;Song, Hyok;Choi, Byeong-Ho;Ho, Yo-Sung
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.37 no.4A
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    • pp.239-249
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    • 2012
  • Recently, the virtual view generation method using depth data is employed to support the advanced stereoscopic and auto-stereoscopic displays. Although depth data is invisible to user at 3D video rendering, its accuracy is very important since it determines the quality of generated virtual view image. Many works are related to such depth enhancement exploiting a time-of-flight (TOF) camera. In this paper, we propose a fast 3D scene capturing system using one TOF camera at center and two high-resolution cameras at both sides. Since we need two depth data for both color cameras, we obtain two views' depth data from the center using the 3D warping technique. Holes in warped depth maps are filled by referring to the surrounded background depth values. In order to reduce mismatches of object boundaries between the depth and color images, we used the joint bilateral filter on the warped depth data. Finally, using two color images and depth maps, we generated 10 additional intermediate images. To realize fast capturing system, we implemented the proposed system using multi-threading technique. Experimental results show that the proposed capturing system captured two viewpoints' color and depth videos in real-time and generated 10 additional views at 7 fps.

A Comparative Study on Government R&D Evaluation System in Selected Countries (주요국의 정부 연구개발(R&D) 평가제도에 관한 비교 연구)

  • Kim, Jong-Woon;Ha, Kyu-Soo
    • Journal of Digital Convergence
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    • v.11 no.4
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    • pp.77-90
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    • 2013
  • This study is to seek measures for streamlining the evaluation system by analyzing the examples of advanced countries. This study was conducted, based on the relevant government policy documents and previous research papers, in the manner of comparing and analyzing the issues and cases regarding the government evaluation system of public-funded R&D programs in selected countries. In Korea, a national R&D performance evaluation system was introduced by law in 2006. In United States, Obama government has enhanced government performance management by signed into law the GPRA Modernezation Act of 2010. The Japanese Government issued a newly revised Guideline on National R&D Evaluation in late 2012. European Union has also been constantly updating its evaluation system for Framework Programmes(FPs) begun since 1984. This study gets some insights from the recent development of R&D evaluation in the other countries. It is important for the government R&D evaluation system to be in line with national S&T policy and agency's mission. In micro views, specific evaluation approaches and methods by types of various R&D programs should be more illustratively developed. Additionally it is suggested to monitor recent trends and techniques on R&D evaluation by participating in activities to communicate and share their knowledge and experiences in international evaluation research networks.

The Effects of Science and Art Integrated Program on Brain Activity of Gifted Students in Science (과학과 미술 통합프로그램이 초등과학영재의 뇌 활성에 미치는 효과)

  • Kwon, Young-Sik;Lee, Kil-Jae
    • Journal of Korean Elementary Science Education
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    • v.32 no.4
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    • pp.567-580
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    • 2013
  • This study is to activate gifted students' brains for creativity ability and also an integrated science and art teaching program. The learning programs integrating science and art, which have 30 periods and 10 topics on art and the knowledge of science, were developed dependant on five steps - observing, having interests and curiosity, experimental designing and performing, internalizing, and expressing in an arts-based manner. This programs were applied to 20 senior gifted students in Y Elementary School in Gyeonggi province, by one group pretest-posttest design. The results from these integrated programs of science and art are as follows: First, in the performance of science tasks, prefrontal lobe(F7, FT7) of left brain increase the relative power of theta wave, whereas in the performance of drawing tasks increase the relative power of beta wave in prefrontal lobe(FP1) of left brain, bilateral frontal(F7, F3, Fz, F4, F8, FT7, FC3, FCz), bilateral temporal(T7, TP7, TP8, P7), parietal lobe of left brain(CP3, CPz, P3, Pz), bilateral occipital(O1, Oz, O2). Second, in the performance of science tasks, the relative power of beta wave activity in the left temporal lobe(T7) of the brains of talented students in science significantly decreased whereas it was greatly activated in another part, the left frontal lobe(F3) of the brain (p<.05). Third, in the performance of drawing tasks, the relative power of theta wave activity in five areas of the brain, namely the left temporal lobe(T7), the left frontal lobe(F3), the right frontal lobe(F4), and the left and right parietal lobes of gifted students in science who took the course of the integrated programs, was considerably increased statistically(p<.05). On top of that, these programs were especially effective in balancing the symmetrical development of both cerebral hemispheres by multiplying theta wave activity in the frontal lobes(F3, F4) and the parietal lobes(CP3, P3, P4), which are particularly related to creative thinking. According to the results of this study of brain-based teaching strategies combining science and art, it is an effective program to develop overall activate gifted students' brains for creativity ability. This is expected to be utilized to activate the brain areas for creativity of gifted students in science.