• 제목/요약/키워드: FHA

검색결과 46건 처리시간 0.024초

피각부 자발성 뇌내출혈의 혈종흡입술을 위한 지표 (Guidelines for Free-Hand Aspiration(FHA) of Putaminal Hemorrhage)

  • 임신길;오민석;임준섭;강명기;곽연상;박승규;송경배;김한웅
    • Journal of Korean Neurosurgical Society
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    • 제30권sup2호
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    • pp.294-299
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    • 2001
  • Objectives : CT-guided stereotactic evacuation for spontaneous intracerebral hemorrhage can minimize the brain damage and can be performed safely and simply under local anesthesia. But that procedure is time consuming and has a risk of rebleeding because of the stress during head pin fixation. So authors describe easy and precise guidelines for FHA of putaminal hemorrhage without stereotactic instrument. Methods and Materials : We analyzed the data of 298 patients who underwent CT-guided stereotactic aspiration of putaminal hematoma in our hospital between January 1990 and December 2000. We divided the patients into three groups according to the location of hematoma : anterior portion, middle portion and posterior portion of putamen. Total number of catheters inserted into the hematoma were 345 and there were with regard to the direction and depth of catheters. Results : Proposed guidelines of catheter insertion to putaminal hemorrhage in our institution. 1) hematoma at the anterior portion of putamen ; Direction of catheter was the midpupillary line of the eye and the point intersecting a line drawn from the burr hole to a point between external auditory meatus(EOM) and 1cm posterior to EOM. Depth of catheter was 6-6.5cm. 2) hematoma at the middle portion of putamen ; Direction of catheter was the midpupillary line of the the eye and the point intersecting a line drawn from the burr hole to a point between 1cm and 2cm posterior to EOM. Depth of catheter was 6.5-7cm. 3) hematoma at the posterior portion of putamen ; Direction of catheter was 15 degree laterally from the midpupillary line of the eye and the point intersecting a line drawn from the burr hole to a point between 2cm and 3cm posterior to EOM. Depth of catheter was 7-7.5cm. We have performed FHA of putaminal hemorrhage in 48 cases according to this guideline. All catheter were inserted exactly at the center of hematoma and average operation time was about 30 minutes. Conclusion : Our proposed guidelines for putaminal hemorrhage are considered to be safe and simple method with similar accuracy and rapid decompression compared with traditional stereotactic method. Main advantages of this technique were unnecessity of stereotactic frame application and less time requirement for hematoma removal.

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원전 화재위험도분석에서 전기회로분석 검증방안에 관한 연구 (A Study on the Verification Scheme for Electrical Circuit Analysis of Fire Hazard Analysis in Nuclear Power Plant)

  • 임현태;오승준;김위경
    • 한국안전학회지
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    • 제30권3호
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    • pp.114-122
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    • 2015
  • In a fire hazard analysis (FHA) for nuclear power plant, various electrical circuit analyses are performed in the parts of fire loading analysis, fire modeling analysis, separation criteria analysis, associated circuit analysis, and multiple spurious operation analysis. Thus, electrical circuit analyses are very important areas so that reliability of the analysis results should be assured. This study is to establish essential electrical elements for each analysis for verification of the reliability of the electrical circuit analyses in the fire hazard analysis for nuclear power plants. Applying the results derived by the study to domestic nuclear power plants, it is expected to determine the adequacy of the fire hazard analysis report and contribute to the reliability of the fire hazard analysis of those plants.

A high speed electro-hydraulic no leakage servo valve using multilayered piezoelectric devices (PZT) and an observer

  • Yokota, Shinichi;Park, Jung-Ho;Fuwa, Akihiko
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 1994년도 Proceedings of the Korea Automatic Control Conference, 9th (KACC) ; Taejeon, Korea; 17-20 Oct. 1994
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    • pp.54-59
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    • 1994
  • In this study, a high-speed servo valve with no outer leakage is developed, which is used to drive flexible hydraulic actuators (FHA) for extreme environments. In the valve, multilayered PZT devices are used to drive a spool directly and quickly. A bellows is also used to prevent outer leak from the clearance between the spool and the sleeve. Employing a disturbance observer, the lack of the system damping of the valve is improved by feeding back the estimated velocity of the spool, as well as the estimated disturbance is fed back to eliminate effectively the hysteresis between input voltage and output displacement of the PZT devices.

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기능적 안전성 분석 기법을 적용한 안전성 요구사항 관리 체계 구축 방안 연구 (The study of Developement Safety Requirement management system using functional hazard analysis technic)

  • 홍선호;조연옥
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2007년도 춘계학술대회 논문집
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    • pp.1216-1220
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    • 2007
  • All the systems can be used properly for the original purpose when they can make the functions required for the users be concrete. Especially in the case that many technical systems are integrated like railroad systems, physically useful systems could be built if requirements analyses applying systems engineering and the process of functional design had to be supported. This paper is intended to review and present the measures and procedures to correctly supply the systems to users by giving systems manufactures and suppliers requirements in order to supply safe systems using safety analysis techniques named FHA(Functional Hazard Analysis) and Hazop Study.

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트랜스포머 Cantilever 모델을 이용한 LLC 공진형 컨버터 설계 (Design of LLC Resonant Converters using Transformer Cantilever Model)

  • 김민중;유승희;김동희;이병국
    • 전력전자학회:학술대회논문집
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    • 전력전자학회 2013년도 전력전자학술대회 논문집
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    • pp.297-298
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    • 2013
  • 본 논문에서는 LLC 공진형 컨버터의 트랜스포머를 Cantilever 모델로 등가화하여 공진 네트워크를 설계하기 위한 과정을 제시한다. 트랜스포머의 결합계수를 고려하여 누설 인덕턴스와 자화인덕턴스의 크기를 계산한다. 그 결과로 얻어진 파라미터를 이용하여 기본파 분석 (First Harmonic Approximation, FHA)을 통해 LLC 공진형 컨버터의 전압 이득관계를 분석한다. 제시한 설계방법을 적용하여 500W급 LLC 공진형 컨버터를 제작 구현함으로써 설계과정의 타당성을 검증한다.

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An Optimization Design of the Diode Clamped Multi-Level Converter for Coaxial Inductive Power Transfer on the Low Voltage DC Micro-grid

  • Pairindra, Worapong;Khomfoi, Surin
    • Journal of Electrical Engineering and Technology
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    • 제13권1호
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    • pp.333-344
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    • 2018
  • This proposed paper aims for the high efficiency contactless power transfer in household dc power distribution. A 300 W five-level diode clamped multi-level converter with 300 Vdc input dc link bus is employed for the power transferring task and the output voltage range is controlled at 48 Vdc. The inner and outer solenoid coils are used for inductive power transfer (IPT) transformer with the 200 kHz switching frequency for designed power density. Therefore, to achieve the converter efficiency above 95%, the LLC series resonant with fundamental harmonic analysis (FHA) and the calculated switching angles are used as an optimized tool for designing the system resonant tank. The validations of this approached topology are illustrated in both MATLAB/Simulink simulation and implementation.

고전압 커패시터 충전을 위한 3상 직병렬 공진형 컨버터 설계 및 구현 (Design and Implementation of a 3-phase LCC Resonant Converter for High Voltage Capacitor Charger)

  • 배영석;이병하;구인수;장성록
    • 전력전자학회:학술대회논문집
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    • 전력전자학회 2019년도 전력전자학술대회
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    • pp.305-306
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    • 2019
  • 본 논문에서는 고전압 커패시터 충전용 3상 LCC 공진형 컨버터를 설계하고 제작하였다. 고전압 커패시터 충전시간과 충전전압간에 선형성을 확보하기 위하여 컨버터는 충전 전 구간에서 정전류원으로 동작하도록 설계되었다. 공진탱크 설계를 위해서 FHA(Fundamental Harmonic Analysis) 기법을 이용하여 첨예도(Q; Quality factor)와 기저 주파수 변동에 따른 입출력 전류이득특성을 도출하였고 이를 바탕으로 28.8kJ/s의 충전속도를 가지며 최대 충전전압은 10kV 인 3상 LCC 공진형 컨버터를 제작하였다. 제작된 컨버터는 10kV, 600kJ 규격의 12mF 고전압 커패시터를 이용한 충전 실험을 통해 설계의 타당성을 확인하였다.

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우리나라 영아에서 3가 정제 백일해 항원 DTaP 백신의 면역원성 및 안전성 (The immunogenicity and safety of three-component DTaP vaccine in Korean infants)

  • 강진한;김종현;이정현;이수영;홍영진;김창휘
    • Clinical and Experimental Pediatrics
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    • 제50권4호
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    • pp.355-362
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    • 2007
  • 목 적 : 3가 항원 DTaP 백신을 3회 기초 접종 받은 건강한 국내 영아에서 면역원성 및 안전성을 평가하고자 하였다. 방 법 : 2004년 4월부터 2005년 4월까지 5개 연구 참여 대학병원에서 제태기간 32주 이상에서 태어난 건강한 영아에게 생후 2, 4, 6개월에 3가 항원 DTaP 백신($Infanrix^{(R)}$)을 대퇴부 전외측에 접종하여 접종 전 혈청과 3차 접종 1개월 후 혈청에서 디프테리아, 파상풍, PT, FHA, PRN 항원에 대한 항체를 측정하여 면역원성을 평가하였고, 접종 후 3일 내에 발생이 예상되는 국소 및 전신 이상반응을 적극 관찰하였고 3주내에 발생한 모든 이상반응을 관찰하여 안전성 평가를 실시하였다. 한편, 2가 항원 DTaP 백신을 접종 받은 14명을 대조군으로 설정하여 연구군과 동일한 방법으로 면역원성을 평가하여 비교하였다. 결 과 : 60명에서 실시된 연구군의 면역원성 평가에서 디프테리아, 파상풍, FHA, PRN 항원에 대한 항체 양전율은 100%이었고, PT 항원에 대한 항체 양전율은 98.3%이었다. 한편 대조군에서 디프테리아, 파상풍, PT, FHA 항원에 대한 항체 양전율은 100%이었으나 PRN 항원에 대한 항체 양전율은 50%이었다. 147명에서 확인된 이상반응 평가에서 연구 기간동안 연구 백신과 인과관계가 있는 중증 이상반응은 없었고, 3일 내에 특이한 치료 및 처치가 없이 자연 소멸되는 국소 및 전신 이상반응만 관찰되었으며 접종 차수별 이상반응의 증가도 없었다. 결 론 : 이상의 결과를 볼 때에 3가 항원 DTaP 백신($Infanrix^{(R)}$)은 국내 영아 기초 접종에 유효한 백신임을 확인할 수 있었고, 국내에서 가장 많이 사용되고 있는 2가 DTaP 백신에 비해 PRN항원에 대한 항체의 면역원성이 높은 이점이 있음을 확인하였다. 그러나 향후 더욱 많은 대상을 통한 연구가 이루어져 이런 결과를 재입증하여야 할 것이고, 추가 접종에 대한 동일한 연구도 요구된다.

Condylar positioning changes following unilateral sagittal split ramus osteotomy in patients with mandibular prognathism

  • Kim, Myung-In;Kim, Jun-Hwa;Jung, Seunggon;Park, Hong-Ju;Oh, Hee-Kyun;Ryu, Sun-Youl;Kook, Min-Suk
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제37권
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    • pp.36.1-36.7
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    • 2015
  • Background: This study was performed to evaluate three-dimensional positional change of the condyle using three-dimensional computed tomography (3D-CT) following unilateral sagittal split ramus osteotomy (USSRO) in patients with mandibular prognathism. Methods: This study examined two patients exhibiting skeletal class III malocclusion with facial asymmetry who underwent USSRO for a mandibular setback. 3D-CT was performed before surgery, immediately after surgery, and 6 months postoperatively. After creating 3D-CT images by using the In-vivo $5^{TM}$ program, the axial plane, coronal plane, and sagittal plane were configured. Three-dimensional positional changes from each plane to the condyle, axial condylar head axis angle (AHA), axial condylar head position (AHP), frontal condylar head axis angle (FHA), frontal condylar head position (FHP), sagittal condylar head axis angle (SHA), and sagittal condylar head position (SHP) of the two patients were measured before surgery, immediately after surgery, and 6 months postoperatively. Results: In the first patient, medial rotation of the operated condyle in AHA and anterior rotation in SHA were observed. There were no significant changes after surgery in AHP, FHP, and SHP after surgery. In the second patient, medial rotation of the operated condyle in AHA and lateral rotation of the operated condyle in FHA were observed. There were no significant changes in AHP, FHP, and SHP postoperatively. This indicates that in USSRO, postoperative movement of the condylar head is insignificant; however, medial rotation of the condylar head is possible. Although three-dimensional changes were observed, these were not clinically significant. Conclusions: The results of this study suggest that although three-dimensional changes in condylar head position are observed in patients post SSRO, there are no significant changes that would clinically affect the patient.

옥수수 유전자 기능 분석을 위한 전사인자의 이해 (Transcription Factor for Gene Function Analysis in Maize)

  • 문준철;김재윤;백성범;권영업;송기태;이병무
    • 한국작물학회지
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    • 제59권3호
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    • pp.263-281
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    • 2014
  • 전사인자는 식물에서 유전자 발현을 조절하기 위해 필수적이며, 유전자의 promoter나 enhancer 부위에 결합하며, 기본 전사 조절, 전사의 향상, 발달, 세포내 신호전달, 환경에 반응, 세포 주기의 조절 등의 역할을 수행한다. 옥수수 게놈의 염기서열 분석은 전사인자의 유전자 발현 조절의 기작을 이해하는데 도움을 줄 것으로 기대된다. 과거 옥수수의 전체 게놈의 중복으로 옥수수에서 4,000개 이상의 전사인자가 코딩 될 것으로 예상된다. 본 논문에서는 옥수수의 ABI3/VP1, AP2/EREBP, ARF, ARID, AS2, AUX/IAA, BES1, bHLH, bZIP, C2C2-CO-like, C2C2-Dof, C2C2-GATA, C2C2-YABBY, C2H2, E2F/DP, FHA, GARP-ARR-B, GeBP, GRAS, HMG, HSF, MADS, MYB, MYB-related, NAC, PHD, WRKY 전사인자의 특징을 간략히 서술하고, 전사인자의 염기서열을 분석하여 sequence logo를 통하여 각각의 도메인을 표시하였다. 이러한 전사인자 및 관련된 유전자의 분자생물학적 연구는 옥수수에서 중요한 기능을 하는 유전자의 발굴 및 육종을 위한 목표 유전자의 선발에 도움을 줄 것으로 기대된다.