• Parasites, Hosts and Diseases
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• v.60 no.2
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• pp.117-126
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• 2022

Cystatin, a cysteine protease inhibitor found in many parasites, plays important roles in immune evasion. This study analyzed the molecular characteristics of a cystatin from Fasciola hepatica (FhCystatin) and expressed recombinant FhCystatin (rFhcystatin) to investigate the immune modulatory effects on lipopolysaccharide-induced proliferation, migration, cytokine secretion, nitric oxide (NO) production, and apoptosis in mouse macrophages. The FhCystatin gene encoded 116 amino acids and contained a conserved cystatin-like domain. rFhCystatin significantly inhibited the activity of cathepsin B. rFhCystatin bound to the surface of mouse RAW264.7 cells, significantly inhibited cell proliferation and promoted apoptosis. Moreover, rFhCystatin inhibited the expression of cellular nitric oxide, interleukin-6, and tumor necrosis factor-α, and promoted the expression of transforming growth factor-β and interleukin-10. These results showed that FhCystatin played an important role in regulating the activity of mouse macrophages. Our findings provide new insights into mechanisms underlying the immune evasion and contribute to the exploration of potential targets for the development of new drug to control F. hepatica infection.

• Proceedings of the KWS Conference
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• 2002.05a
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• pp.222-223
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• 2002

• Proceedings of the Korean Institute of Communication Sciences Conference
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• 1985.10a
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• pp.56-58
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• 1985

• The korean journal of orthodontics
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• v.37 no.4
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• pp.260-271
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• 2007

The purpose of this study was to evaluate the relationships between the occlusal plane angle and craniofacial skeletal pattern in relation to anterior overbite. Methods: Lateral cephalograms of 90 adults with skeletal class III malocclusions were traced and measured to analyze skeletal factors and occlusal plane angles. In terms of anterior overbite, all patients were classified into 3 subgroups of positive overbite, edgebite, and negative overbite groups. All measurements were evaluated statistically by ANOVA and Duncan's Post Hoc, and correlation coefficients were evaluated among measurements. Results: In this study, some skeletal measurements (saddle angle, articular angle, Y axis, AFH, SN-FH, SN-Mn, FH-Mn) showed a significant difference among the 3 groups in relation to overbite changes. Correlation coefficient showed that PFH/AFH, SN-Mn, Mx-Mn, and FH-Mn showed a significant difference with FH-Occ, Mx-Occ, and Mn-Occ. Regression analysis showed that Mx-Mn had a determination coefficient of 0.714, 0.560, and 0.677 in relation to FH-Occ, Mx-Occ, and Mn-Occ, respectively. Conclusion: This study suggests that consideration of the occlusal plane in relation to the maxillomandibular vertical skeletal state enable the establishment of a more predictable orthognathic surgery result.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.3
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• pp.941-955
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• 2015

In dual-channel networks (DCNs), all frequency hopping (FH) sequences used for data channels are chosen from the original FH sequence used for the control channel by shifting different initial phases. As the number of data channels increases, the hitting frequency point problem becomes considerably serious because DCNs is non-orthogonal synchronization network and FH sequences are non-orthogonal. The increasing severity of the hitting frequency point problem consequently reduces the resource utilization efficiency. To solve this problem, we propose a novel hitting frequency point collision avoidance method, which consists of a sequence-selection strategy called sliding correlation (SC) and a collision avoidance strategy called keeping silent on hitting frequency point (KSHF). SC is used to find the optimal phase-shifted FH sequence with the minimum number of hitting frequency points for a new data channel. The hitting frequency points and their locations in this optimal sequence are also derived for KSHF according to SC strategy. In KSHF, the transceivers transmit or receive symbol information not on the hitting frequency point, but on the next frequency point during the next FH period. Analytical and simulation results demonstrate that unlike the traditional method, the proposed method can effectively reduce the number of hitting frequency points and improve the efficiency of the code resource utilization.

• Journal of the Korea Institute of Military Science and Technology
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• v.14 no.1
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• pp.69-73
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• 2011

In the defence wireless communications, conventional Anti-Jamming techniques(Frequency Hopping/Spread Spectrum or Direct Sequence/Spread Spectrum) are used to overcome a intentional interfering signals which are single/multitone or partial band jammer etc. DS/SS techniques is very strong on tone jamming signal but not to be on a partial band jammer. So FH/SS AJ performances are expected method of an substitution of DS/SS, however FH/SS could not have good performance on some BMTJ(Band Multi-tone Jammer). So this paper proposes FH-CSS (Frequency Hopped - Chirp Spread Spectrum) to get more robustness against jammers(BMTJ, PBNJ) and analyze the AJ performances.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.13 no.2
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• pp.120-126
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• 1988

In this paper the performance of the asynchronous Repeated FH/MFSK system for the CDMA(Code Division Multiple Access) was analyzed. Actually there was no difference in the probabilities of hit of frequency between Random Coding method and frequency hopping pattern vector suggested by Einarsso. Actual situation was adopted as a model in thie simulation, on the assumption thet;a:there was no Noise, Multipath propagation, b:there was only mutual interference. c:the number of users M was given. Also it was found that there is almost no deviation between the value calculated from the formula of word error probability expressed by bound and that obtained from this simulation.

• Journal of Korea Multimedia Society
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• v.16 no.5
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• pp.601-609
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• 2013

One of the most serious factors constraining the next generation cellular mobile consumer communication systems will be the severe co-channel interference experienced at the cell edge. Such a capacity-degrading impairment combined with the limited available spectrum resource makes it essential to develop more spectrally efficient solutions to enhance the system performance and enrich the mobile user's application services. This paper proposes a unique hybrid method of frequency hopping (FH) and subcarrier-reuse-partitioning that can maximize the system capacity by efficiently utilizing the available spectrum while at the same time reduce the co-channel interference effect. The main feature of the proposed method is that it applies an optimal combination of different frequency reuse factors (FRF) and FH-subcarrier allocation patterns into the partitioned cell regions. From the simulation results, it is shown that the proposed method can achieve the optimum number of subcarrier subsets according to the frequency-reuse distance and results in better performance than the fixed FRF methods, for a given partitioning arrangement. The results are presented in the context of both blocking probability and BER performances. It will also be shown how the proposed scheme is well suited to FH-OFDMA based cellular systems aiming at low co-channel interference performance and optimized number of subcarriers.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.8 no.4
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• pp.415-425
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• 1997

Although FHSS has many advantages over conventional digital radio communication system, field application has been so far hampered due to its complicated synchronization. In this paper, a new FHSS system is proposed which one FH signal modulated with GMSK and one chip delayed FH signal than former are sent from transmitter, and this is recovered by matching process at a heterodyne correlator in receiver; thus eliminates synchronization as a whole. Through analysis and experiment, we assure that there is possibility in this. The exper- imental result from 915~929 MHz bandwidth with 31 chips is investigated in the environment of AWGN.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.25 no.2
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• pp.251-254
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• 2014

In this paper, we studied a technique of extracting a Frequency Hopping(FH) signal for analysis using high-speed parallel processing structure. Unlike fixed frequency signal, FH signal is difficult to detect and analyze because FH systems use many random frequencies instead of a single carrier frequency. To solve this problem we designed a method that analyze FH signal using high-speed parallel processing. In order to apply parallel processing, we use CUDA using GPU and compare single processing with prarallel processing. As a result, using CUDA on a GPU is about 8.53 times faster than single processing.