• Title/Summary/Keyword: FASR

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THE FREQUENCY AGILE SOLAR RADIOTELESCOPE

  • GARY DALE E.
    • Journal of The Korean Astronomical Society
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    • v.36 no.spc1
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    • pp.135-143
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    • 2003
  • Solar radio astronomy is about to undergo a revolution with the advent of a new radio synthesis array, the Frequency Agile Solar Radiotelescope (FASR). The array will consist of more than 100 antennas (5000 baselines), and will be designed to meet the special challenges of solar imaging. It will produce high-quality images at hundreds of frequencies in the range 20 MHz-24 GHz. We briefly describe the plans for the instrument, and then concentrate on the range of science that is expected to be addressed, using current state-of-the-art solar radio observations and modeling to illustrate FASR performance. We end with an assessment of the current status of the instrument, and plans for future.

Study for Block Cipher Operating Mode Using Counter (카운터를 사용한 블록암호 운영모드에 관한 연구)

  • Yang, Sang-Keun;Kim, Gil-Ho;Park, Chang-Soo;Cho, Gyeong-Yeon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2008.10a
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    • pp.243-246
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    • 2008
  • This thesis suggests block cipher operating mode using ASR(Arithmetic Shift Register). ASR is ratted arithmetic shift register which is sequence that is not 0 but initial value $A_0$ multiplies not 0 or 1 but free number D on $GF(2^n)$. This thesis proposes ASR mode which changes output multiplying d and Floating ASR mode which has same function but having strengthened stability altering d. If we use ASR's output as a counter, there's advantage that it has higher stability and better speed than CTR. Also, ASR mode and FASR mode have advantage of Random access which is not being functioned on CTR mode, they can be widely used to any part which Random access is needed.

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Sensitization of TNFα and Agonistic FAS/CD95 Antibody-Induced Apoptosis by INFγ on Neuroblastoma Cells (신경모세포종에서 IFNγ에 의한 TNFα와 길항적 FAS/CD95항체 유도성 세포고사의 감작화)

  • Bang, Ho Il;Kim, Jong Duck;Choi, Du Young
    • Clinical and Experimental Pediatrics
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    • v.46 no.7
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    • pp.702-709
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    • 2003
  • Purpose : $IFN{\gamma}$ sentitizes many tumor cells to $TNF{\alpha}$ and FASL-mediated apoptosis by enhancing the expression of TNF or FAS/CD95 receptor and modulating the activation of caspase and Bcl-2 family. It has been reported that $IFN{\gamma}$ and $TNF{\alpha}$ synergistically caused differentiation and growth inhibition of neuroblastoma cells. Even though some neuroblastoma cell express FASR/FASL on the cell surface, they could not induce apoptosis by ligation of the FAS/CD95 receptor. But the treatment of $IFN{\gamma}$ is reported to induce apoptosis in some neuroblastoma cell lines through the CD95/CD95L autocrine circuit. In this study, we examined whether $IFN{\gamma}$ could affect $TNF{\alpha}$ and agonistic FAS/CD95 antibody(CH-11)-induced apoptosis against neuroblastoma cell lines that had shown diverse drug sensitivity and resistance. Methods : CHLA-15, CHLA-90 and LA-N-2 neuroblastoma cells were cultured in IMDM and treated with recombinant $IFN{\gamma}$, $TNF{\alpha}$ and CH-11 antibody. Cell viability was measured by DIMSCAN with a fluorescent calcein-AM. Apoptosis was analyzed through flow cytometry using Annexin V-PE and 7-ADD staining and confirmed by pancaspase and caspase-8 blocking experiments. The expression of TNF RI and FAS/CD95 receptor was evaluated by flow cytometry using the corresponding antibody and PE-conjugated secondary antibody. Results : $IFN{\gamma}$ or $TNF{\alpha}$ alone had no demonstrable cytotoxic effects, whereas both cytokines in combination induced apoptosis synergistically in CHLA-15 and CHLA-90 cells. Although there was no cytotoxicity with the ligation of CH-11 alone in CHLA-90 cells, pretreatment of $IFN{\gamma}$ increased the sensitivity of CH-11-mediated apoptosis. The expression of TNFRI and FAS/CD95R were non-specifically enhanced after treatment of $IFN{\gamma}$ without relation to sensitivity to $TNF{\alpha}$ and CH-11. This finding suggest up-regulation of both receptors may contribute to sensitization of $TNF{\alpha}$ and CH-11-mediated apoptosis by $IFN{\gamma}$ in only sensitive cell lines. Conclusion : $IFN{\gamma}$ induced sensitization of $TNF{\alpha}$ and agonistic FAS/CD95 antibody-mediated apoptosis on some neuroblastoma cells through up-regulation of TNFRI and FAS/CD95 receptor.