• Applied Biological Chemistry
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• v.49 no.1
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• pp.25-29
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• 2006

This study was carried out to isolate the possible anti-tumor promoters from the citrus peel (Citrus natsudaidai Hayata). We fractionated the cold-pressed oil of citrus peel by column chromatography, HPLC and TLC. The analysis on column chromate-graphy yielded seven peaks $(F-I{\sim}F-VII)$, all of which showed single spot on TLC analysis ($R_f$ for $F-I{\sim}VIII$; 0.31, 0.13, 0.13, 0.78, 0.79, 0.69 and 0.84). Among the seven fractions, three fractions (F-I, -II and F-IV) were re-analyzed on HPLC, also showing single peak except for one fraction (F-IV) which was divided two peaks. The retention times $(R_f)$ of F-I and F-II was 3 min. and 2.5 min., respectively, but these of two peaks from F-IV were 2 min. and 4.5 min., respectively. Since the area of the latter peak (4.5 min.) was very smaller than that of the former one (2 min.), it is considered that the latter one did not appear on TLC analysis. The inhibitory effect on tumor promoter 12-O-tetradecanoylphorbol-13-acetate(TPA)-induced Epstein-Barr virus activation in Raji cells was tested for the seven fraction obtained. It decreased in order of F-VI (82.3+1.3%) > F-I (80.4+1.6%) > F-II (77.2+0.9%) > F-III (75.0+1.2%) > F-IV (74.1=1.0%) > F-V (71.0+1.1%) > F-VII (70.2+1.2%). These results imply that some constiuents contained in citrus peels have the inhibitory activity of TPA-induced tumor promotion.

• Journal of Korean Society for Quality Management
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• v.29 no.2
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• pp.37-45
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• 2001

A survival variable is a non-negative random variable X with distribution function F(t) satisfying F(0) : 0 and a survival function F(t): 1-F(t). This variable is said to be New Better than Used of specified age t$_{0}$ if F(x+ t$_{0}$)$\leq$F(x).F(t$_{0}$) for all x$\geq$0 and a fixed t$_{0}$. We propose the test for H$_{0}$ : F(x+t$_{0}$)=F(x).F(t$_{0}$) for all x$\geq$0 against H$_1$: F(x+t$_{0}$) $\leq$ F(x).F(t$_{0}$) for all x$\geq$0 when the specified age to is unknown but can be estimated from the data when t$_{0}$=ζ$_{p}$, the pth percentile of F. This test statistic, which is based on the normalized spacings between the ordered observations, is readily applied in the case of small sample. Also, our test is more simple than Ahmad's test (1998). Finally, the performance of our test is presented.our test is presented.

• The Journal of the Acoustical Society of Korea
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• v.19 no.5
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• pp.60-64
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• 2000

This paper studies the relation between the Fundamental Frequency (F0) and the formants of simple vowels in the Korean language sung by sopranos. It is hewn that, in soprano singing, the F0 of a vowel affects its formants. For this reason the formants of simple vowels sung by sopranos must be considered in all over the soprano singing range. We recorded the five simple vowel sounds /a/, /e/, /i/, /o/, and /u/ sung by five professional sopranos from A3 (220.0Hz) to A5 (880.0Hz) in the major scale and compared the formants of the sung vowels with those of spoken vowels. We observed that F1 and F2 of sung vowels were stable in low F0 (lower than B4) but in high F0 (higher than B4), F1 and F2 lost their stabilities. In the case of /a/, /o/, and /u/, the slope of the F1-F2 graph was about 2.6, and those of the F0-F2 and F0-Fl graphs were 2.2-2.5 and 0.7-1.0, respectively. And as the F0 increases, the F1 and F2 of sung vowels /a/, /e/, /i/, /o/, and /u/ were almost the same. At A5, the Fl and F2 of five sung vowels had the same values. This results suggest that the relation between the F0 and the formants be used to synthesize soprano's singing vowels.

• Phonetics and Speech Sciences
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• v.15 no.3
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• pp.17-25
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• 2023

This study examines the fundamental frequency(f0) distribution of 2,740 Korean speakers in a dialogue speech corpus. Praat and R were used for the collection and analysis of acoustical f0 data after removing extreme values considering the interquartile f0 range of the intonational phrases produced by each individual speaker. Results showed that the average f0 value of all speakers was 185 Hz and the median value was 187 Hz. The f0 data showed a positively skewed distribution of 0.11, and the kurtosis was -0.09, which is close to the normal distribution. The pitch values of daily conversations varied in the range of 238 Hz. Further examination of the male and female groups showed distinct median f0 values: 114 Hz for males and 199 Hz for females. A t-test between the two groups yielded a significant difference. The skewness representing the distribution shape was 1.24 for the male group and 0.58 for the female group. The kurtosis was 5.21 and 3.88 for the male and female groups, and the male group values appeared leptokurtic. A regression analysis between the median f0 and age yielded a slope of 0.15 for the male group and -0.586 for the female group, which indicated a divergent relationship. In conclusion, a normative f0 distribution of different Korean age and sex groups can be examined in the conversational speech corpus recorded by a massive number of participants. However, more rigorous data might be required to define a relation between age and f0 values.

• Journal of Korean Society of Environmental Engineers
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• v.36 no.6
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• pp.434-441
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• 2014

This study is purposed to measure airborne asbestos concentrations at demolition sites and surrounding areas of asbestos containing buildings in Seoul and examine whether the measurement results correspond with allowable exhaust standard for asbestos of the Asbestos Safety Control Act. The airborne asbestos concentrations for 37 sites were below the detection limit ($7fiber/mm^2$) in 101 (35%) out of 288 samples. The whole average airborne asbestos concentration in 37 sites was $0.003{\pm}0.002f/cc$(max 0.0013 f/cc) and almost the whole airborne asbestos concentrations were satisfied with allowable exhaust standard for asbestos, 0.01 f/cc, of the Asbestos Safety Control Act. So possibility of asbestos exposure is not yet a major concern at current levels for sites demolished of asbestos containing buildings in Seoul. Looking at each sampling point, the average airborne asbestos concentrations in boundary line of site, entrance of sanitation, around the workplace (in), around the workplace (out), negative pressure units, storage area for waste, outlet for waste and residential area of residents were respectively $0.002{\pm}0.002f/cc$, $0.004{\pm}0.002f/cc$, $0.004{\pm}0.002f/cc$, $0.004{\pm}0.002f/cc$, $0.004{\pm}0.002f/cc$, $0.005{\pm}0.004f/cc$, $0.005{\pm}0.003f/cc$ and $0.003{\pm}0.002f/cc$. As a result, all sampling points of study were satisfied with allowable exhaust standard for asbestos, 0.01 f/cc, of the Asbestos Safety Control Act.

• Journal of Veterinary Clinics
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• v.14 no.2
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• pp.151-160
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• 1997

This study was performed to assess clinical signs, sedative and physiologic effects of a combination of fentanyl, azaperone and xylazine (F-A-X). The experiments were divided into four groups; xylazine 0.1mg/kg (X 0.1), F-A-X 0.05 MG/KG (F-A-X 0.05), F-A-X 0.1 MG/KG (F-A-X 0.1) and F-A-X 0.2mg/kg (F-A-X 0.2). Heart rates were decreased in all groups. Respiratory rates were decreased in other groups, but increased in F-A-X 0.2. Body temperatures were in normal ranges. After administration of F-A-X, most of cattle were recumbency and did not respond to needle prick. Duration of sedation was prolonged with increasing dosages. F-A-X did not induce sufficient analgesia for dehorning. Side effects were salivation and urination in all, but they were much less in F-A-X groups than those in X 0.1. Intermittent apnea and bloat were observed in F-A-X 0.2. Serum chemistry values were in normal ranges exvept for hyperglycemia invreased thorough experimental time. Based on above results, it may be concluded that F-A-X is effective preanesthetic with low dosage of 0.05~0.1 mg/kg being useful for immobilization or manipulation without tissue incision in cattle.

• The Korean Journal of Zoology
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• v.26 no.3
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• pp.211-217
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• 1983

Genetic polymorphism of transferrin $(T_f)$ subtypes in Jeju population was studied by isoelectric focusing of human sera on polyacrylamide gels under high voltage, and haptolobin (Hp) polymorphism in Seoul and Jeju population was studied by polyacrylamide gel electrophoresis. Among 946 normal samples, three common types of transferrin, $T_{f}C_{1}, T_{f}C_{1}-C_{2} and T_{f}C_{2}$ were observed with some variants migrating slower than $T_{f}C$ subtypes, while among 139 patient (hepatitis) samples, only three common types were found. The gene frequencies were calculated as follows; in normal population, $T_{f}C^{1}$ was 0.7220; $T_{f}C^{2}, 0.2743; T_{f}D^{Jeju}, 0.0037$, and in patient population, $T_{f}C^{1} was 0.7194; T_{f}C^{2}, 0.2806$ respectively. Among 460 samples in Seoul and 502 in Jeju population, three types of haptoglobin, Hp 1-1, Hp 2-1 and Hp 2-2 were observed. The gene frequency of $Hp^1$ was 0.304, $Hp^2$, 0.696 in Seoul and in Jeju, $Hp^1$ was 0.269 and $Hp^2$, 0.731, respectively. The frequencies of the genes and the polymorphic phenotypes were discussed comparatively with the other populations.

• Journal of the Chungcheong Mathematical Society
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• v.23 no.4
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• pp.679-689
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• 2010

By developing and using certain operators like those initiated by Burchnall-Chaundy, the authors aim at investigating several decomposition formulas associated with the $Kamp{\acute{e}}$ de $F{\acute{e}}riet$ function $F_{2:0;0}^{0:3;3}$ [x, y]. For this purpose, many operator identities involving inverse pairs of symbolic operators are constructed. By employing their decomposition formulas, they also present a new group of integral representations of Eulerian type for the $Kamp{\acute{e}}$ de $F{\acute{e}}riet$ function $F_{2:0;0}^{0:3;3}$ [x, y], some of which include several hypergeometric functions such as $_2F_1$, $_3F_2$, an Appell function $F_3$, and the $Kamp{\acute{e}}$ de $F{\acute{e}}riet$ functions $F_{2:0;0}^{0:3;3}$ and $F_{1:0;1}^{0:2;3}$.

• Journal of applied mathematics & informatics
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• v.20 no.1_2
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• pp.479-483
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• 2006

For any fixed $\lambda\leq-\frac{1}{2}$, there exists $f(\eta){\in}C^1[0,+\infty)$ which satisfies the following nonlinear boundary value problem f'+ff'+$\lambda(l-f'^2)=0$ a.e.in $(0,+\infty)$, f(0)=0, f'(0) = 0, $f'(+\infty)=1$, which arises in boundary layer theory in fluid mechanics.

• The Journal of the Acoustical Society of Korea
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• v.18 no.8
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• pp.75-83
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• 1999

This paper proposes a new F0 contour model for intonation control in speech synthesis. We assume that the F0 contour of an utterance can be described using a sequence of time-overlapping events, which determine the fluctuation of a given F0 contour, described by asymmetric Gaussian functions. In addition, We propose a parameter estimation algorithm for the proposed model. The proposed model is not developed with a particular phonological theory in mind, and can be used in both F0 contour analysis and synthesis. For testing our F0 model, we collected 500 sentences from various genres and built a corresponding speech corpus uttered by a professional female announcer. As n result of F0 resynthesis experiment using the proposed model, the RMSE was 7.87Hz for given speech corpus.