• Title/Summary/Keyword: F. thunbergii

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Anthelmintic Natural Products against Clonorchis sinensis and the Analogues (간디스토마에 작용하는 천연물 및 그 유사체)

  • 안병준;이재구
    • YAKHAK HOEJI
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    • v.30 no.5
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    • pp.253-265
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    • 1986
  • Among 230 species of herbal drugs screened, thirty one show the anthelmintic activities in vitro against Clonorchis sinensis, the chinese liver fluke. The active substances have been isolated and their structures identified. Some of the active substances and their derivatives have been synthesized, followed by anthelmintic activity tests. The extracts from the active drugs cause damages in organs of the adult worm in the hepatic duct of rabbit. Some fresh water fish, which function as bad hosts for the fluke, excrete defense substances against the cercaria of the fluke. The defense substances have been isolated from Cyprinus carpio and Cyprinus carpio nudus, followed by structural identification. The results are summarized as follows: l) The bark of Machilus thunbergii as well as the seed of Schizandra chinensis contain meso-dihydro-guaiaretic acid as the anthelmintic component. Among derivatives synthesized, 4-phenyl-1-((3, 4-dihydroxyphenyl)-, 4-phenyl-1-(3-hydroxy-4-methoxy phenyl)-and 4-phenyl-1-(4-hydroxy-3-methoxy phenyl)-2, 3-dimethyl butanes show considerable activities. Administration of the bark extract mainly damages the bladder of the adult worm. 2) The active substance from the roasted fruit of Prunus mume is 2-hydroxymethylfurfural. This substance is produced during the roasting process. Administration of the fruitextract causes a damage of the bladder of the adult worm. 3) The active substance from the root of Scutellaria baicalensis is 5.2'-dihydroxy-6, 7, 8, 6'-tetramethoxyflavone. 4) Beside alantolactone, a very strong anthelmintic component is contained in the root of Inula helenium. Administration of the root extract causes irreversible damage on the worm, affecting mainly the reproductive organs. 5) The cercaricidal substances from the epidermis of C. carpio and C. carpio nudus are ethyl linoleate and linoleic acid, respertively. 6) The cercaricidal substances from various kinds of fresh water fish have different $R_f$ values, implying that the defense substances are species-specific. Unexpectedly, the fish with good host function, for example Pseudorasbora parva, excrete the defense substances, too. The defense substances are possibly organ-specific in individual species; the organs essenstial for the existence of the species excrete the defense substances, allowing other parts to be invaded by the cercaria. 7) The cercaricidal fraction of Carassius carassius is detected only in the fish which have been collected during the summer time from May to September, Its secretion is not dependent on water temperature. Thus, it seems to be possible that the secretion of the defense substance would be stimulated through a contact between the fish and cercaria.

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Classification of Polygonatum spp. Collections Based on Multivariate Analysis (다변량 분석에 의한 둥굴레속 식물의 분류)

  • Yun, Jong-Sun;Son, Suk-Yeong;Kim, Ik-Hwan;Hong, Eui-Yon;Yun, Tae;Lee, Cheol-Hee;Jong, Seung-Keun;Park, Sang-Il
    • Korean Journal of Medicinal Crop Science
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    • v.10 no.5
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    • pp.333-339
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    • 2002
  • This study was conducted to obtain the basic data for practical use of the Polygonatum genetic resources. The 20 collections were analyzed by principal component analysis of 8 characters and cluster analysis. In the principal analysis, the first, the second and the third components contributed 54.10%, 18.95% and 11.62% of the variations, respectively. The cumulative contribution from the first to the third principal components was 84.68%. The first principal component was related to shape and size of plant, and assimilatory, reserve and reproductive organs. The second principal component was related to growth and development of plant, and reserve organ. And the third principal component was related to growth and development of plant. Based on cluster analysis, the 20 collections were classified into 4 distinct groups with the average distance greater than 0.7 between groups. Group I was Polygonatum sibiricum $D_{ELAR}$ and Group II included P. odoratum var. pluriflorum $O_{HWI}$, P. odoratum var. pluriflorum $O_{HWI}$ for 'Variegatum' Y. Lee, for. nov., P. odoratum var. thunbergii $H_{ARA}$ and P. odoratum var. maximowiczii $K_{OIDZ}$. GroupIII was P. involucratum $M_{AXIM}$, P. desoulavyi $K_{OMAROV}$ and P. humile $F_{ISHER}$ ex. $M_{AXIM}$. And GroupIV included P. lasianthum var. coreanum $N_{AKAI}$ and P. inflatum $K_{OMAROV}$.

Revegetation and human( II ) -Revegetation of volcanic denuded land- (녹화(綠化)와 인간(人間)( II ) -화산성(火山性) 황폐지(荒廢地)의 녹화(綠化)-)

  • Ezaki, Tsugio;Iwamoto, Tohru;Yea, Sun-Young;Chun, Kun-Woo
    • Journal of Forest and Environmental Science
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    • v.17 no.1
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    • pp.88-103
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    • 2001
  • It is one of the important tasks to accurately grasp features of the devastated land to revegetate the denuded, volcanic land. In the present report three factors of such features were discussed : the ash fall phenomenon the overflow of surface water, and the generation of sulfurous acid gas, which are all usual, harmful factors for the successful growth of introduced plants to such area. In addition, it is indicated that to overcome those harmful factors some artificial tools should be applied in such regions before the introduction of pioneer tree species such as Pinus thunbergii and etc. In our three-year pilot study it is found out that the use of mulching sheets developed originally by research members combined together with symbiotic microorganisms such as Pisolithus tinctorus Coker et Couch f. tinctorius was very effective. Experimental plots surveyed throughly in Mt. Fugendake in Nagasaki Prefecture and Mt. Sakurajima in Kagoshima Prefecture showed successful revegetation as models. Finally, for the revegetation of the denuded, volcanic land it is recommended that mulching sheets should be used together with symbiotic microorganisms.

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Studies on the Effect of Environmental Pollution on the Structure of Plant Community (환경오염(環境汚染)이 식물군집(食物群集)에 미치는 영향(影響)에 관(關)한 연구(硏究))

  • Kim, Tae-Wook;Lee, Kyong-Jae;Park, In-Hyeop;Kim, Joon-Seon
    • Korean Journal of Environmental Agriculture
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    • v.2 no.1
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    • pp.35-44
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    • 1983
  • In order to elucidate the change of plant community of natural forests caused by air pollution in the area of Mt. Dosjil of Ulsan city, 25 study subplots, 5 subplots from each 5 plots were set up. These plots lay along gradients of chronic exposure to airborne sulfur dioxide ($SO_2$), fluorides(F) and possibly other pollutants. Total nitrogen, organic matter, available $P_2O_5$, and CEC were generally depressed near industrial sourecs of air pollutants. The author found a total 7 species near sources of air pollutants and 13 species at the utmost plot from air pollutants. Number of individuals, species diversity, evenness, similarity index and biomass were generally depressed near the industrial source of air pollutants. Tolerant plants to air pollution is Cyperus amuricus, Calamagrostis arundinacea, Bidens bipinnata, Cocculus trilobus, Digtaria sanguinalis, Persicaria hydropiper, Pinus thunbergii, Ambrosia artemisiifolia var. elatior, Rhododendron schlippenbachii and Robinia pseudoacacia. It contains 4.41ton/ha of aboveground biomass of Robinia pseudoacacia in damaged forest by air pollution and 39.47ton/ha of it in the non-attacked forest. The annual net production is 0.67ton/ha. yr in damaged forest and $7.73ton/ha{\cdot}yr$ in the non-attacked forest.

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Elucidation of Anti-tumor Initiator and Promoter Derived from Seaweed-2: Investigation of Seaweed Extracts Suppressing Mutagenic Activity of PhIP and MeIQx (해조류 중의 anti-tumor initiator 및 promoter의 해석-2: PhIP와 MeIQx의 돌연변이원성을 억제하는 해조 추출물 소재의 연구)

  • PARK Young-Beom;KIM In-Soo;YOO Sung-Jae;AHN Jong-Khan;LEE Tae-Gee;PARK Douck-Chon;KIM Seon-Bong
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.31 no.4
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    • pp.581-586
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    • 1998
  • The present study was conducted to prepare seaweed extracts suppressing mutagenic activity of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine ( PhIP ) ana 2-amino-3,8-dimethylmidazo[4,5-f]quinoxaline (MeIQx) derived from cooked meat produce. The tumor initiation activity of PhIP and MeIQx was assayed with Ames method using Salmonella typhimurium TA98 in the presence of S-9 mixtures before and after addition of methanol-solubles of seaweed, such as, Phaeophyta; Undaria pinnatifida, Ecklonia stolonifera Ecklonia cava, Laminaia japonica Sargassum fulvellum, Sargassum hornezi, Sargassum miyabei, Sargassum thunbergii, Agarum cribrosum and Hizikia fusifomis, Rhodophpei Porphyra yezoensis, Grateloupia eiliptiut Lomentraria catenata, Ploemium telfairiae and Glarilaria verrucosa, Chlorophyta; Codium fragile, Enteromorpha compresa and Ulva pertusa. Among seaweed tested, Phaeophyta was shown the higher desmutagenic activity than Rhodophyta and Chlorophyta. E. stolonifera, E. cava and S. miyabei, among Phaeophyta exerted the stronger desmutagenic activity (above $90\%$/2 mg). The ethyl acetate, diethyl ether and chlomform extracts except water extracts from E. stolonifera exhibited a high desmutagenic activity. The ethyl acetate extract of E. stolonifera which showed highest activity was fractionated with Sephadex LH20 column chromatography to give active fraction A-7, which showed desmutagenicity of $90\%$/mg against PhIP and $80\%$/mg against MeIQx. The active fraction had the absorbance at 207.7 and 232nm.

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Vegetation Structure and Growth Characteristics of Cryptomeria japonica(Thunb. ex L.f.) D.Don Plantations in the Southern Region of Korea (남부권역 삼나무조림지의 식생구조와 생장특성에 관한연구)

  • Park, Joon hyung;Lee, Kwang Soo;Ju, Nam Gyu;Kang, Young Je;Ryu, Suk Bong;Yoo, Byung Oh;Park, Yong Bae;kim, Hyung Ho;Jung, Su Young
    • Journal of agriculture & life science
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    • v.50 no.1
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    • pp.105-115
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    • 2016
  • This study was carried out to establish the optimum forest management plan for the Cryptomeria japonica plantations in southern inland and Jeju island in Korea. Sixty seven circular sample plots of 0.04ha were established and we surveyed vegetation structure and growth characteristics from three layers(upper, middle, and lower). As a result of cluster analysis obtained by importance values of each tree species, the community type of C. japonica stands were classified into C. japonica group(C1) and C. japonica-C obtusa group. C. obtusa community were also sbudivided into P. thunbergii-Q. serrata group(C2) and Q. serrata-C obtusa group(C3). In tree layers importance value(IV) of C. japonica were 97.2% in C1, 80.7% in C2, and 47.6% in C3 and in sub-tree layers IV were 8.9% in C1, 15.2% in C2, and 5.7% in C3. Especially in C3 there are bamboo species (Smilacina japonica var. lutecarpa and Pseudosasa japonica) it is necessary for us to control them. In shrub layers C. japonica were found in C1(9.2%) and C2(7.0%), but except for C3. In tree layer species diversity indices of each community ranged from the lowest 0.059 in C1 to the highest 0.548 in C3. Dominance ranged from 0.958 in C1 to 0.393 in C3 which may caused by interspecific competition. Current annual increment of diameter growth ranged from 7.01mm/yr to 8.04mm/yr. As a result of our study we recommend the application of proper thinning and pruning for C1 and C2.