• Title/Summary/Keyword: F-P-K Method

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Linear Free Energy Relationship on the Phosphorylation of Acetylcholinesterase by Insecticidal O,O-Diethylphenylphosphate Derivatives (살충성(殺蟲性) O,O-Diethylphenylphosphate유도체(誘導體)들에 의(依)한 Acetylcholinesterase의 Phosphorylation에 미치는 자유(自由)에너지 관계(關係))

  • Sung, Nack-Do
    • Korean Journal of Agricultural Science
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    • v.11 no.1
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    • pp.176-181
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    • 1984
  • Linear free energy relation ship(LFER) on the insecticidal activity of O,O-diethylphenylphosphate (A) and 3,5-dimethylphenyl-O,O-diethylphosphate (B) derivatives were studied by EHT MO calculation method and regression analysis method. LFER between varying substituent constants and $pI_{50}$ constants of phosphates, (A) & (B) were calculated with applying Hammett, Okamoto-Brown, Taft and Swain-Lupton's DSP equations;percent resonance effect(R) and field effect(F) of (A) were %R=33.5 & %F=66.5 and also that of (B) were %R=2 & %F=98, respectively. On the basis of above findings, the insecticidal activities were similar for both (A) and (B), but (B) have larger field and inductive contribution than (A), due to the 3,5-dimethyl group of (B).

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Rresilience in Children with Chronic Illness and in Their Family (만성질환을 가진 아동과 가족의 극복력)

  • Baek, Kyung-Won;Choi, Mi-Hye
    • Child Health Nursing Research
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    • v.12 no.2
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    • pp.223-232
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    • 2006
  • Purpose: The purpose of this study were to describe of resilience in children with chronic illness and family resilience, and to identify their correlations. Method: Data was collected from 108 children and their families, being treated by hospitals C and K in Seoul, who are diagnosed with nephrotic syndrome, IgA nephritis, diabetes, asthma at least six months ago. Descriptive, t-test, One-way ANOVA, and Pearson's Correlation were done. Result: The mean score of resilience in children was 101.31 and family resilience was 60.14. The variable which showed a statistically meaningful difference in the resilience in children according to a general characteristic was the gender of a child (t=6.209, p<.05), diagnosis (F= 6.315, p<.01), age of a mother (t=2.237, p<.05), and school grade (F=12.838, P<.01). In terms of the family resilience according to a general characteristic, the variable showing a statistically meaningful difference was the order of sibling (F=13.468, p<.01). There was significant positive resilience in children between family resilience (r=.356, p<.01). Conclusions: In this study we proposed the implement programs for the increase of the resilience in children with chronic illness. In order to give a positive effect on the resilience in children, implement for the increase of the family resilience is also proposed.

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Analysis on the Correlation Between Vegetation Structure and Environment Factors of the Geumosanseong-inside in Geumosan Provincial Park, in Korea (금오산도립공원의 금오산성 식생구조와 환경요인의 상관관계 분석)

  • Kim, Hyoun-Sook;Park, Gwan-Soo;Lee, Sang-Myong;Lee, Joong-Ku
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.23 no.2
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    • pp.49-67
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    • 2020
  • This study was conducted to compare and analyze forest vegetation distributed in Geumosanseong-inside in Geumosan Provincial Park from 2017.10 to 2019.6. The vegetation structure was classified by the phytosociological method and TWINSPAN and the correlation between the community structure and the environmental factors was analyzed using DCCA ordination analydsis. The vegetation structures are Quercus mongolica, Fraxinus mandshurica, Q. acutissima, Larix leptolepis, Prunus padus and Morus alba community by the phytosociological method and 16 communities under TWINSPAN. The importance value of Q. mongolica(64.5) was the highest, and followed by F. mandshurica, L. leptolepis, Acer pseudosieboldianum, M. alba, P. padus, Q. acutissima, Sorbus alnifolia, P. serrulata var. pubescens, F. sieboldiana, Rhododendron schlippenbachii and Castanea crenata which is consistent with species having the dominance status by analysis of the vegetation structure. As the results of DBH analysis for taxon with high importance values, Q. mongolica and M. alba represented normal distribution, and thus, the dominance status of these species is likely to continue. L. leptolepis will maintain the dominance status due to high density of large individuals as compared with species above medium size. However, it will decrease because of high mortality after increase in age class. F. mandshurica and P. padus continue to show dominance status due to high density of young individuals as compared with species above medium size. Q. acutissima have high density of individuals above intermediate size and low density of young individuals, and thus, will maintain the dominance status. A. pseudosieboldianum, F. sieboldiana and R.schlippenbachii which are arborescent will present continuously high dominance status because of high density of young individuals. Soil analysis shows that whereas pH, Ca2+ and Mg2+ in the research area were lower than the average values of overall forest soil and O.M, T-N, C.E.C and P2O5 were higher. We expected that these results were due to agricultures until 50 years ago in Geumosanseong-inside. As a result of DCCA ordination analysis using eleven environmental factors and communities classified by the phytosociological method analysis showed that Q. mongolica was distributed in the environment with higher elevation and O.M and steep slope, and lower P2O5, Mg2+ and Ca2+. In contrast to F. mandshurica, Q. acutissima was distributed in higher K+ and lower pH. L. leptolepsis was distributed in various environment.

A Study on Changes of Serum $fT_3\;and\;rT_3$ Concentration in Nonthyroidal Critical Illness (비갑상선 중증 질환에서 혈청 $fT_3$$rT_3$의 변화에 관한 연구)

  • Lee, Jong-Wha;Kim, Ju-Ock;Yu, Cheol-Jae;Moon, Youn-Sung;Shin, Young-Tae;Ro, Heung-Kyu
    • The Korean Journal of Nuclear Medicine
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    • v.19 no.1
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    • pp.103-111
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    • 1985
  • Recently changes in thyroid physiology during acute and chronic medical illness were demonstrated. The serum $fT_3,\;rT_3,\;T_4,\;T_3,\;fT_4$, and TSH concentration were measured by radioimmunoassay method in 49 patients with critical illness and 10 normal subjects to assess the change of thyroid function in critical illness. The results were as follows; 1) The mean serum $fT_3$ concentration was $6.68{\pm}1.05pmol/ml$ in normal subjects while in patients with critical illness the serum $fT_3$ concentration was significantly lowered to $1.55{\pm}1.15pmol/ml$(p<0.001). 2) The mean serum $rT_3$ concentration was $0.22{\pm}0.44ng/ml$ in normal subjects and $0.42{\pm}0.37ng/ml$ in patient with critical illness. There was increment in critically ill patients as compared to normal subjects but no statistically significant difference(p>0.05). 3) The mean serum $T_3$ concentration was $1.24{\pm}0.25ng/ml$ in normal subjects and $0.56{\pm}0.56ng/ml$ in patients with criticial illness and there was significant difference in each other(p<0.005). 4) The mean serum $T_4,\;fT_4$, and TSH concentrations were $7.80{\pm}1.02{\mu}g/dl,\;1.26{\pm}0.39ng/dl,\;1.87{\pm}0.45{\mu}U/ml$ in normal subjects respectively and $6.02{\pm}3.06{\mu}g/dl,\;1.46{\pm}0.80ng/dl,\;1.74{\pm}0.79{\mu}U/ml$ in patients with critical illness and there was no significant difference between critically ill patients and normal subjects. 5) The ratio of mean serum concentration of $fT_3$ and $rT_3(fT_3/rT_3)$, $30.42{\pm}5.58$ in normal subjects was significantly higher(p<0.005) than the coresponding patients with critical illness. 6) The mean serum $fT_3$ concentration in expired cases(n=12) during admission was significant difference between expired and survived cases(p<0.005). The mean serum $rT_3$ centration was $0.67{\pm}0.58ng/ml$ in expired cases and $0.34{\pm}0.22ng/ml$ in survived cases with significant difference(p<0.005). Half of the cases who showed less than $3{\mu}g/dl$ of serum $T_4$ level were expired.

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Evaluation of remineralization and acid resistance effect in fluoride varnish by Micro-computed tomography (미세전산화단층촬영술을 이용한 불소바니쉬의 재광화 및 내산성 평가)

  • Oh, Han-Na;Jeong, Seong-Soog;Lee, Hye-Jin;Youn, Hye-Jeong;Jung, Eun-Ju;Ha, Myung-Ok
    • Journal of Korean society of Dental Hygiene
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    • v.10 no.5
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    • pp.947-953
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    • 2010
  • Objectives : The purpose of this investigation was to evaluate the remineralization and acid resistance in fluoride varnish by Micro-computed tomography (micro CT). Methods : Specimens of bovine teeth enamel were embedded in resin, polished and randomly divided into 3 groups (a control group, a NaF solution group, a fluoride varnish group). Each group has 3 specimens that was standardized according to Vickers hardness number (VHN). Specimens were immersed in demineralization solution for 72 hours. The control group had no treatment, the NaF solution group was treated by a 5% NaF solution for 4 minutes, and the fluoride varnish group was treated by a fluoride varnish for one hour. All specimens were subjected to a chemical pH cycling method for 14 days. After a chemical pH cycling method, the density were measured using micro CT. Then, specimens were immersed in each demineralization solution for 72 hours. After demineralization processed, the density were measured using micro CT. Results : 1. The density was significantly higher in the fluoride varnish and 5% NaF solution group than that of the control group after 14 days cycling (p<0.05). And the density value of the fluoride varnish group was higher than that of the 5% NaF solution, with no significant difference. 2. The differences of density after acid resistance treatment were statistically significant among 3 groups(p<0.05). Conclusions : It is suggested that fluoride varnish showed the remineralizing effect and acid resistance effect on the enamel, and micro CT could be used to evaluate the change of enamel lesion.

The Influencing Factors on the Degree of Nurse's Suffering Experience Caring for Terminal Cancer Patient (말기 암 환자를 간호하는 간호사의 고통경험 정도에 영향을 미치는 특성요인)

  • Jo, Kae-Hwa;Kim, Yeong Kyeong
    • Korean Journal of Adult Nursing
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    • v.16 no.3
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    • pp.378-387
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    • 2004
  • Purpose: The study was undertaken to examine the degree of nurse's suffering experience and to identify the influencing factors on nurses' suffering experience in Korea. Method: Data were collected using a questionnaire for 271 nurses working at 5 general hospitals in Daegu and Kyung-book province from Sep. 1, to Sep. 30, 2003. The questionnaire consists of 54 items, general characteristics(10) and nurse's suffering experience(44). All surveys were sorted and studied by frequency analysis, mean score, standard deviation, range, independent t-test, one way ANOVA, Pearson's correlation coefficient and Multiple regression. Result: The findings of this survey indicate 1) The degree of suffering experienced by nurses caring for terminal cancer patients was 2.96; 2) Demographic variables affecting the degree of nurses' suffering experience were age(F=5.62, p=.000), marital status(F=20.53, p=.000), religion(F=5.44, p=.020), career of clinical experience(F=6.96, p=.000), and feelings of end-life care(F=3.11, p=.016); 3) There were slight correlation between the subitem of nurse's suffering experience and general characteristics of subjects. For 'expanding self consciousness', age, career duration, and position; for 'forming empathy with family', age and career duration ; for 'spiritual sublimation', age, and career duration were affected variables. 4) As a result of the multiple regression analysis for predictable variables affecting nurses' suffering, it was found that 'career of clinical experience' was most significant(F=23.100, p=.000). The explanatory power of this regression formula was 17.6%. Conclusion: This study can provide the basic data useful towards improvement of nursing services for terminal cancer patients and the health of the nurse.

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The Relationship among Patients Sick-role Behavior Compliance, Health Belief and Health Locus of Control in Patients with Diabetes Mellitus Visiting Public Health Center (보건소 내소 당뇨병 환자의 건강신념, 건강 통제위성격과 환자역할행위 이행과의 관계)

  • Kong, Kyung-Ja;Tae, Young-Sook;Sahn, Sue-Kyung
    • Journal of Home Health Care Nursing
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    • v.9 no.2
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    • pp.103-113
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    • 2002
  • Purpose: This study was conducted to explore the relationship among health belief. health locus of control and patients sick-role behavior compliance of diabetic mellitus patients visiting public health center. Method: The subjects of this study were 193 of the diabetic patients who were visiting 4 Public Health Center in B city. The instrument used for measuring health belief was Park's(1985). for health locus of control was Wallston. et al's(1978) and for sick-role behavior compliance was Park's(1984). The data were collected with structured questionnaires; total 58 items contained about health belief. health locus of control and sick-role behavior compliance from 1st to 31st July. 2001. The data was analyzed by the SPSS/PC programs using t-test. Pearson's correlation coefficient. ANOVA and Scheffe-test. Result: The average score of the health belief was $57.99\pm9.45$ health locus of control was $66.83\pm9.48$ and sick-role behavior compliance was $42.81\pm7.00$. Statistically significant factors influencing the health belief among social demographic characteristics were family number(F=3.818. p=0.024), monthly income(F=5.153, p=0.002), time of diagnosis(F=3.937. p=0.002) and difficult to control disease(F=5.803. p=0.000). The significant factors influencing the health locus of control were marital status(F=4.669. p=0.010). Also significant factors influencing the sick-role behavior compliance were monthly incomes(F=5.245, p=0.000). the time of diagnosis(F=4.424. p=0.001) and admission to hospital with diabetes(F=9.031. p=0.000). There was negative mild correlation comparatively between health belief and sickrole behavior compliance(r=-0.142, p<0.05) but no correlation in sensitiveness/severity, barrier, benefit(p<0.05). There was no correlation between internal. external. chance health locus of control and sick-role behavior compliance (P>0.05). Conclusion: There was a negative weak relationship between health locus of control and patient's sick role behavior compliance. Therefore further study to investigate the relating factor of the sick role behavior compliance among above of middle aged diabetes mellitus patients is necessary.

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Electrical properties and ATP-sensitive K+ channel density of the rat substantia nigra pars compacta neurons (랫드 흑질 신경세포의 전기적 특성과 ATP-sensitive K+채널의 전류밀도)

  • Han, Seong-kyu;Park, Jin-bong;Ryu, Pan-dong
    • Korean Journal of Veterinary Research
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    • v.40 no.2
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    • pp.275-282
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    • 2000
  • Substantia nigra is known to highly express glibenclamide binding site, a protein associated to ATP-sensitive $K^{+}$ ($K_{ATP}$) channel in the brain. However, the functional expression of $K_{ATP}$ channels in the area is not yet known. In this work, we attempted to estimate the functional expression of $K_{ATP}$ channels in neurons of the substantia nigra pars compacta (SNC) in young rats using slice patch clamp technique. Membrane properties and whole cell currents attributable to $K_{ATP}$ channel were examined by the current and voltage clamp method, respectively. In SNC, two sub-populations of neurons were identified. Type I (rhythmic) neurons had low frequency rebound action potentials ($4.5{\pm}0.25Hz$, n=75) with rhythmic pattern. Type II (phasic) neurons were characterized by faster firing ($22.7{\pm}3.16Hz$, n=12). Both time constants and membrane capacitance in rhythmic neurons ($34.0{\pm}1.27$ ms, $270.0{\pm}11.83$ pF) and phasic neurons ($23.7{\pm}4.16$ ms, $184{\pm}35.2$ pF) were also significantly different. The current density of $K_{ATP}$ channels was $6.1{\pm}1.47$ pA/pF (2.44~15.43 pA/pF, n=8) at rhythmic neurons of young rats. Our data show that in SNC there are two types of neurons with different electrical properties and the density of $K_{ATP}$, channel of rhythmic neuron is about 600 channels per neuron.

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Evaluation of Certain Plant Extracts and Antagonists Against Fusarium solani and Alternaria tenuissima, the Incitants of Root Rot and Die-Back Diseases of Mulberry

  • Seetha, Ramulu J.;Raja, Gopal Reddy C.;Ramanjaneyulu, R.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.20 no.1
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    • pp.1-5
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    • 2010
  • The studies have been conducted to control the soil borne fungal pathogens viz, Fusarium solani (Mart) Sacc. and Alternaria tenuissima the incitants of root rot and die-back diseases on mulberry stem cuttings planted in the mulberry nurseries and also in established mulberry gardens ten plant extracts with 10% concentration except Lantana camara (undiluted) were tested through poisoned food technique and four biofungicides were also screened by dual culture method under in vitro conditions. Plant extract of Prosopis juliflora showed the maximum inhibition on the mycelial growth (81.2% over A. tenuissima and 80.0% over F. solani) and followed by L. camara (66.7% over A. tenuissima and 68.9% over F. solani). Among the antagonists Pseudomonas fluorescens and Trichoderma viride showed maximum inhibition on the mycelial growth of both pathogenic fungi. The promising plant extracts (P. juliflora and L. camara) and antagonists (P. fluorescens and T. viride) were tested against both the pathogenic fungi under in vivo conditions along with the existing popular chemical Mancozeb. All the tested plant products and bio-fungicides showed inhibitory effect on both fungi. But the maximum survival percentage of mulberry cuttings was recorded in the treatment with T. viride (95% against F. solani and 90% against A. tenuisssima) followed by P. fluorescens (90% against both fungi) and T. harzianum (80% against F. solani and 85% against A. tenuisssima). Incase of the treatments with plant extracts and chemical fungicide the P. juliflora (60% against F. solani and 55% against A. tenuisssima) showed higher survival percentage and followed by L. camara (55% against F. solani and 50% against A. tenuisssima) and Mancozeb (55% against both fungi). In case of control only 10% of survival was recorded in F. solani inoculated cuttings and 15% survival in A. tenuissima inoculated cuttings.

Dysmenorrhea and Menstrual Attitudes in Adult Women (성인여성의 월경곤란증과 월경에 대한 태도)

  • Lee, Eun-Hee;Kim, Jeung-Im;Kim, Hye-Won;Lee, Hye-Kyung;Lee, Sook-Hee;Kang, Nam-Mi;Hur, Myung-Haeng;Park, Young-Sook
    • Women's Health Nursing
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    • v.9 no.2
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    • pp.105-112
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    • 2003
  • The survey was conducted to look out the characteristics of menstruation and it's management, menstrual attitudes and degree of dysmenorrhea in the adult women. The subjects were 601 women, aged 20 year old and over, selected by convenient sampling. The results were as follows; 1. The mean age of the subjects was 29.1 years, the subjects were consisted of 346 unmarried and 304 delivery experienced person. 2. The characteristics of menstruation were as follows ; irregular 167 person(27.8%), painful 451 person(75%), mean score of pain was 5.9 point and first day was most severe(45.1%). On the while, they have used the method to manage the pain such as "endure 50.8%", "to have a medicine 31.5%". 3. Menstrual attitudes were as follows; attitudes was negative such as it was meaningful as a woman (78.9%), only for birth a baby (51.6%), and menstruation was acceptable (42.9%), hope to get away(28.8%). 4. The degree of dysmenorrhea was a significant difference by age(F=4.0, P<0.01). Especially, in the subcategory, it was significant except for water retension. That is, lower concent ration(F=2.60, p<0.05), negative affect(F=3.09, p<0.05), behavior change(F=6.41, p<0.050), pain(F=3.89, p<0.01), autonomic nerve response(F=2.80, p<0.05). We can conclude there were many women to have negative attitudes to menstruation and first day was most severe dysmenorrhea and it was different by age. From this results, we may suggest as follows; 1. We suggest the program for women to have a positive attitudes will be developed. 2. We can suggest that we need to develop the active and effective method to control dysmenorrhea in the first day during menstruation.

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