• Korean Journal of Occupational Health Nursing
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• v.32 no.2
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• pp.68-78
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• 2023

Purpose: This study aimed to determine the moderating effect of self-esteem on the perception of death and the meaning of life among hospital nurses. Methods: The participants were 167 nurses working in two tertiary general hospitals located in city B. Data were collected from September 8 to 21, 2022. SPSS/WIN 29.0 was used for analysis along with t-test, ANOVA, Pearson correlation coefficients, and hierarchical multiple regression. Results: The study showed that the meaning of life was significantly correlated with the perception of death (r=.34, p<.001) and self-esteem (r=.31, p<.001). Self-esteem significantly moderated the relationship between the perception of death and the meaning of life (F=16.00, p<.001). Conclusion: Self-esteem may moderate the relationship between the two factors. This means that nurses with higher self-esteem have a greater tendency for their perception of death to positively impact their meaning of life. Therefore, for hospital nurses to discover the meaning of life, it is necessary to develop and apply a self-esteem enhancement program specialized for each clinical career.

• Journal of The Korean Society of Integrative Medicine
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• v.8 no.4
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• pp.253-263
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• 2020

Purpose : The purpose of this study was conducted to compare the fear of falling, self-efficacy and fall prevention behavior according to the fall experience of the elderly. Methods : The subjects of this study were 162 elderly in B metropolitan city. The data collection period was from September 10th to November 30th of 2018. The collected data was processed using SPSS 21.0 and was analyzed using descriptive statistics, t-test, ANOVA, Scheffe's test. Results : The mean scores for fear of falling according to the fall experience and no fall experience of the elderly were 2.28±0.63 and 1.84±0.64 respectively and the results showed that fear of falling (t=4.26, p<.001) and self-efficacy of falling (t=3.88, p<.001) were significantly different between the two groups, but the mean scores for fall prevention behavior according to the fall experience and no fall experience of the elderly were 1.63±0.20 and 1.67±0.17 respectively and there was no significantly different in fall prevention behavior (t=-1.16, p=.25). Fear of falling according to the fall experience was significantly different by age (F=3.25, p<.05) and physical activity related to daily life (F=13.22, p<.001). Self-efficacy according to the fall experience was significantly different by age (F=3.03, p<.05), income per month (F=3.74, p<.05) and physical activity related to daily life (F=11.99, p<.001). But fall prevention behavior was no significantly different of general characteristics. Fear of falling according to the no fall experience was significantly different by age (F=3.37, p<.05), marriage status (F=3.37, p<.05), education level (F=5.15, p<.01), income per month (F=3.58, p<.05) and physical activity related to daily life (F=15.71, p<.001). Self-efficacy according to the no fall experience was significantly different by sex (t=2.32, p<.05), age (F=5.20, p<.01), marriage status (F=5.04, p<.01), education level (F=6.55, p<.001), income per month (F=5.99, p<.001) and physical activity related to daily life (F=18.86, p<.001). Fall prevention behavior was significantly different by marriage status (F=3.51, p<.05). Conclusion : The results of this study suggest the following : it is necessary to develop a program that can lower the fear of falling in the elderly and to increase the self-efficacy of falling, and to develop an education program that can improve the elderly's practice of fall prevention behavior regardless of the fall experience and to verify its effectiveness.

• 종축개량
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• v.20 no.1
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• pp.93-102
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• 1998

3원교잡종의 지육지방축척과 육질에 대한 종료종모돈(두록종:D, 버크셔종:B, 매산돈:M)의 영향을 보기 위해, 랜드레이스종과 대요크셔종의 F1(LW) 종빈돈에 D, B 또는 M종의 3품종의 종모돈을 교배시켜 얻은 3원교 잡종(LWD, LWB, LWM)에 대해서 지육의 지방 축적량, 로스육의 물리적 특성과 화학적 조성 또는 근육섬유의 특성, 근육과 피하지방의 지방산 조성을 비교 검토했다. 시험돈은 3원교잡종 각각에 대해서 거세돈 수컷과 암컷을 각각 6두씩, 합계 36두를 공시했다. 단사(單飼), 무제한 급여 하에서 체중이 30kg에서 105kg가 될 때까지 사육했다. 도살한 돼지의 지육우반환(枝肉右半丸)의 제5-6, 8-9, 11-12, 13-14 흉추(胸椎) 간, 제16흉추-제1요추(腰推) 또는 최후요추-제1선추(仙推)간의 횡단면지방의 면적비율은 어떠한 부분에도 LMW이 LWD, LWB보다 통계적으로 유의가 많았다. 로스육의 물리적 특성치인 Tenderness는 $LWM961.3Kgw/cm^2)$ of $LWD(84.13KgW/cm^2)$와 $LWD(87.22KgW/cm^2)$보다 유의적으로 부드럽고, Pliability는 역으로 LWM이 LWD, LWB보다 유의 있게 낮았다. 또 로스육의 근육내 지방함량은 $LWM(3.23\%)$이 $LWD(2.32\%)$과 $LWB(2.35\%)$보다 유의성 있게 많았고, 가열 손실율(加熱損失率)은 LWM이 LWD, LWB보다 유의성 있게 높았다. 근섬유경(筋纖維經)은 LWD가 LWB, LWM보다 큰 경향으로 인정되어 지고, 근속(筋束)의 횡단면적은 LWD가 LWB 또는 LWM보다 유의 있게 조밀했다. LWM은 근육 내 지방산인 오레인산이 LWD, LWB보다 훨씬 높았고, 불포화 지방산의 비율이 높았다. 이상의 결과 종료종모돈이 3원교잡종의 육질에 영향을 미친다는 것이 명확하게 되었다.

• Journal of the Korean Chemical Society
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• v.37 no.5
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• pp.473-476
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• 1993

Dipropargyldiphenylmetane, $C_{19}H_{16}, crystallizes in a monoclinic space group $C2/_c$$ with a = 11304(3), b = 20.799(5), c = 6.622(2)${\AA}$, ${\beta} = 112.8(3)^{\circ}$, Z = 4, V = 1435.3${\AA}^3,\;F(000)\;=\;520,\;D_c\;=\;1.14g{\cdot}cm^{-3}$ and ${\mu}\;=\;0.32\;cm^{-1}$. The structure was solved by direct methods and all non-H atoms were identified in the E-map. The final refinement gave R = 0.055 from 1328 unique observed reflections with I $\geq$ -1.0 $\sigma(I).$ The molecule belongs to the point group $C_2$ of Symmetry by possessing the 2-fold axis which coincides witeh the crystallographic symmetry axis in the unit cell. The linear propargyl moiety is nearly $perpendicular(94.2)^{\circ}$ to the molecular plane of the benzene ring. The internal angle of methane carbon atoms in $108.1(1)^{\circ}$, bonding to the benzene and the propargyl moiety with the bond lengths of 1.530(2) and $1.560(2)\AA$, respectively. The shortest contant between the molecules is $3.538(2)\AA$ between C(9) and C(9) (-x, y, -1/2-z).

• Journal of Life Science
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• v.28 no.7
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• pp.802-810
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• 2018

Aging is accompanied by changes in the body, such as graying hair, wrinkles, and black spots composed of lipid peroxides and proteins. Melanin is a polymer substance produced by an oxidation polymerization reaction from tyrosine, and it determines the color of hair and skin. It has been reported that melanin is synthesized by melanocyte, and its excessive production by reactive oxygen species is associated with aging. The purpose of this study was to determine the direct effects of Musa paradisiaca peel ethanolic extract (MPEE) on antioxidative activity and melanin synthesis. It was observed that the antioxidant activity of MPEE was similar to that of vitamin C, a positive control, in both DPPH radical scavenging assay and reducing power assay. In order to examine cytotoxicity prior to cell experimentation, 3-(4,5-dimethythiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was performed for B16F1 cells. MPEE was not cytotoxic at $32{\mu}g/ml$ or less. In addition, MPEE increased melanin synthesis in live cells in addition to tyrosinase activity and melanin synthesis in dihydroxyphenylalanine (DOPA)-oxidation assay in vitro. Moreover, MPEE increased melanin synthesis in cells aged by pretreatment with $H_2O_2$. The expression levels of tyrosinase-related protein (TRP)-1, TRP-2, and superoxide dismutase (SOD)-2 by western blot analysis were increased in the presence of MPEE. These results suggest that MPEE could promote the melanin synthesis as an antioxidative substance.

• Microbiology and Biotechnology Letters
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• v.48 no.4
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• pp.556-563
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• 2020

The purpose of this study was to verify the antioxidant and whitening effects of fermented Ambrosia trifida L. extract (ATFE) and to verify its usefulness as a cosmetic material. The antioxidant effects were measured by assessing the electron-donating capacity and 2,2-azino-bis(3-ethyl-benthiazoline-6-sulfonic acid) (ABTS) radical scavenging ability of these extracts. ATFE was shown to have an electron-donation capacity of 68.4% at a concentration of 1000 ㎍/ml. While its ABTS+ radical scavenging ability was shown to be 58.7% at the same concentration. The ATFE tyrosinase inhibitory effect, which is related to skin-whitening, was shown to be 32.35% at a concentration of 1000 ㎍/ml and a cell viability assay using melanoma cells showed a 14.8% reduction in cell viability at a concentration of 100 ㎍/ml. Surviving cells were then used in western blot analyses to evaluate the protein inhibitory effects of ATFE at 25, 50, 100 ㎍/ml where β-actin was used as a positive control. The whitening effects of these extracts were also evaluated by western blot and show that the expression of microphthalmia-associated transcription factors, Tyrosinase-related proteins (TRP)-1, TRP-2 and Tyrosinase were all inhibited, 51.14%, 55.4%, 38.6%, 83.77% respectively, at 100 ㎍/ml ATFE. The efficacy of the whitening effects was verified and the suitability of ATFE as a cosmetic material was assured.

• Journal of Life Science
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• v.32 no.3
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• pp.222-231
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• 2022

This study aimed to confirm the possibility of being used as a cosmetic material material through the verification of the whitening and anti-inflammatory activities of an ethyl acetate fraction from Glechoma hederacea var. longituba (GHEA). The observed electron donating and ABTS⁺ radical scavenging abilities of GHEA were 89.6% and 88.7%, respectively, at 1,000 ㎍/ml concentration, with a tyrosinase inhibitory effect of 22.3% at the same concentration. For cell viability, a rate of 80% or more was observed in all concentrations that treated GHEA on melanoma and macrophage cells. Protein and mRNA expression inhibition was measured by Western blot and RT-PCR for 25, 50, and 100 ㎍/ ml concentrations, and it was confirmed that expression decreases in a concentration-dependent manner as GHEA concentration increases. The inhibition of the whitening-related factors MITF and TRP-2 were superior following GHEA treatment than those of the control group treated with kojic acid of 100 ㎍/ml concentration. For tyrosinase, the lowest mRNA expression rate was 29.1% at 100 ㎍/ml which confirmed excellent inhibition. In analyzing the effects of pro-inflammatory cytokines IL-1β, IL-6, and TNF-α on protein and mRNA expression, IL-6 and TNF-α showed high protein and mRNA inhibition compared to a vitamin C control group. Based on these experimental results, GHEA could be applied as a natural cosmetic material.

• Journal of Convergence for Information Technology
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• v.12 no.3
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• pp.244-251
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• 2022

This study attempted to investigate the applicability of Geranium maculatum extract as a cosmeceutical ingredient. For this, DPPH, ABTS and FRAP assays were performed to assess radical scavenging activities. To evaluate antioxidant substances, in addition, polyphenol and flavonoid concentrations were measured. Furthermore, cytotoxicity, whitening and anti-inflammatory tests were conducted, using B16F10 and RAW 264.7 cells, and the results found the followings: In the DPPH and ABTS assays, 265.8 mg ascorbic acid/g and 168.5 mg ascorbic acid/g of antioxidant capacities were found respectively. According to the FRAP assay, 1 mg Geranium maculatum extract was same with ascorbic acid 229±9 ㎍ in terms of reducing power. In polyphenol and flavonoid concentrations, 32.989±1.610 mg/g and 11.098±0.261 mg/g were observed each. The above results show that cells survived in the test concentrations more than 80 percent, confirming the low toxicity of Geranium maculatum extract. According to whitening testing, melanin synthesis was reduced depending on concentration, and at the same time, 40.62±2.07% of melanin production inhibition was found at 100 ㎍/mL. In anti-inflammatory testing, inflammation was reduced depending on concentration, and 27.86±2.82% of inhibition of inflammation was detected simultaneously, confirming the applicability of Geranium maculatum extract as a cosmeceutical ingredient.

• Journal of Korean Society of Environmental Engineers
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• v.34 no.8
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• pp.574-582
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• 2012

This study presents the concentrations of the polycyclic aromatic hydrocarbons (PAHs) listed as priority pollutants by United States Environmental Protection Agency (US EPA), in 98 sludges from 54 industrial wastewater treatment facilities of South Korea. The mean concentrations of ${\Sigma}_{16}PAHs$ were ranged from 32.5 ${\mu}g/kg-dw$ to 1189.3 ${\mu}g/kg-dw$ by industries, and the highest content was found in the petrochemical industry, followed by chemical, clothing manufacturing and dying, pulp and papermaking, secondary wastewater treatment, and food/beverage producing industries. Comparisons to the EU and Danish standards of ${\Sigma}_{16}PAHs$ in sewage sludge for land application showed only two samples (one from petrochemical, and the other from chemical industry) exceeded the limits. ANOVA test with PAH concentrations as variables revealed no statistically significant influences by industrial types and sampling time (i.e., seasonal variations). Pearson correlations between individual PAHs showed strong relationships (r>0.7) among 4-ring PAHs. Concentrations of acenaphthylene, anthracene, fluoranthene, benzo(a)anthracene, benzo(f)fluoranthene, benzo(k)fluoranthene, benzo(a)pyrene presented strong correlations to ${\Sigma}_{16}PAHs$. Principal component analysis discriminated entire samples into three groups by two principal components (PC1 and PC2) with 70% of data variations, in which industrial types were not of importance, but a dominance of certain PAHs. Samples in group-I, which is high PC1 and low PC2, were characterized by a dominance of 2-ring PAHs, and in group-II, PC1 and PC2 showed a linear relation, was dominant 4-ring PAHs. Group-III with low PC1 and high PC2 includes 17 samples showing a noticeably high contribution of 3-ring PAHs to ${\Sigma}_{16}PAHs$. This study provides concentrations of PAHs in industrial sludges collected from a wide variety of sources (six industrial types) and two seasons of sampling events, and the comparison of ${\Sigma}_{16}PAHs$ with other studies are also discussed.

• Korean Journal of Food Science and Technology
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• v.53 no.4
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• pp.408-415
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• 2021

This study was conducted to evaluate various beneficial functions of soaked and germinated Robusta coffee beans. Vietnam Robusta coffee beans were soaked in purified water or Salicornia extract for 12 h. The total polyphenol content of non-germinated coffee (NGC), Salicornia extract-germinated coffee (SGC), and water-germinated coffee (WGC) was found to be 16.71-20.17%. First, NGC, SGC, and WGC at concentrations of 25-100 ㎍/mL showed significant anti-oxidant effects on DPPH radical scavenging and xanthine oxidase activity. NGC, SGC, and WGC also inhibited tyrosinase activity and melanin formation in α-MSH-induced B16F10 cells. In addition, the anti-obesity property of germinated coffees was tested by the Oil Red O staining method. NGC, SGC, and WGC inhibited adipogenesis in 3T3-L1 cells without cytotoxicity. Taken together, germinated Robusta coffees with enhanced flavor showed beneficial multifunctional effects, such as anti-oxidant, anti-melanogenesis, and anti-adipogenesis effects.