• Proceedings of the Korean Geotechical Society Conference
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• 2002.03a
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• pp.63-70
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• 2002

In tunnel construction, the information on the rock quality and the location of fault or fracture are crucial for economical design of support pattern and for safe construction of the tunnel. The grade of rock is commonly estimated through the observation with the naked eye of recovered cores in drilling or from physical parameters obtained by their laboratory test. Since drilling cost is quite expensive and terrains of planned sites for tunnel construction are rough in many cases, however, only limited information could be provided by core drilling Electrical resistivity and EM surveys may be a clue to get over this difficulty. Thus we have investigated electrical resistivity and EM field data providing regional Information of the rock Quality and delineating fault and fracture over a rough terrain. In this paper, we present some case histories using electrical resistivity and EM survey for the site investigation of tunnel construction. Through electrical resistivity and EM survey, the range and depth of coal seam was clearly estimated, cavities were detected in limestone area, and weak zones such as joint, fault and fracture have been delineated.

• Journal of the Korean Society of Safety
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• v.28 no.3
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• pp.118-122
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• 2013

For safe evacuation in the fire disaster, the evacuees must find the exit and evacuate quickly. Especially, if the evacuees don't know the location of the exit, they have to depend on the evacuation guidance system. Because the more smoke spread, the less visibility is decreasing, it is difficult to find the way to the exit by the naked eye. For theses reasons, the evacuation guidance system is highly important. However, the evacuation guidance system without change of direction has the risk that introduce to the dangerous area. In the evacuation safety assessment scenario by the evacuation simulation has the same problem. Because the evacuee in the simulation evacuate by the shortest route to the exit, the simulation result is same like the evacuation without the evacuation guidance system. In this study, it was used with MAS (Multi Agent System)-based simulation program including the evacuation guidance system to implement the change of evacuation by fire. Using this method, confidence of evacuation safety assessment can be increase.

• Proceedings of the KSRS Conference
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• 2002.10a
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• pp.423-427
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• 2002

Contrary to the traditional text-based information, 4S(GIS,GNSS,SIIS,ITS) information can contribute to the citizen's welfare in upcoming era. Recently, GSIS(Geo-Spatial Information System) has been applied and stressed out in various fields. As analyzed the data from GSIS arena, the position information of objects and targets is crucial and critical. Therefore, several methods of getting and knowing position are proposed and developed. From this perspective, Position collection and processing are the heart of 4S technology. We develop 4S-Van that enables real-time acquisition of position and attribute information and accurate image data in remote site. In this study, the configuration of 4S-Van equipped with GPS, INS, CCD and eye-safe laser scanner is shown and the merits of DGPS/INS integration approach for geo-referencing is briefly discussed. The algorithm of DGPS/INS integration fur determination of six parameters of motion is eccential in the 4S-Van to avoid or simplify the complicated computation such as photogrammetric triangulation. 4S-Van has the application of Laser-Mobile Mapping System for three-dimensional data acquisition that merges the texture information from CCD camera. The technique is also applied in the fields of virtual reality, car navigation, computer games, planning and management, city transportation, mobile communication, etc.

• Journal of the Korean Applied Science and Technology
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• v.35 no.4
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• pp.1407-1412
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• 2018

This study suggests that ozonated olive oil can kill a wide variety of microorganisms while being less toxic but in the case of administration or abdominal administration, the human body is harmless. In Korea, there is no animal stability test yet. In this study, ozonated olive oil was used to test the stability of the animal through the eye. Specific experiments were performed to evaluate animal Ocular irritation safe test of ozonized oil (high concentration) in rabbits. and Observation of the treatment point on the test substance, ozonated olive oil showed no Ocular irritation in both the non-washing group and the washing group.

• Journal of Cerebrovascular and Endovascular Neurosurgery
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• v.20 no.4
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• pp.241-247
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• 2018

Treatment of paraclinoid aneurysms weather by surgery, or endovascular embolization has a risk of visual loss due to optic neuropathy, or diplopia due to cranial nerve palsies. Visual complications occur immediately after the clipping, whereas they can occur variable time after endovascular coiling. Recently, endovascular coiling for paraclinoid aneurysm is regarded as a safe and feasible treatment. But it still has risks of acute thromboembolic complication, or cranial nerve palsies. A 45-year-old woman was referred from local hospital to our hospital due to ruptured large ICA dorsal wall aneurysm. A total of 12 coils (195 cm) were used for obliteration of aneurysm. Postoperative diffusion weighted image showed no abnormal signal intensity lesion and magnetic resonance angiography demonstrated no sign of vasospasm, or vessel narrowing. But, she complained visual problem 23 days after coil embolization. Ophthalmologist confirmed the left optic disc atrophy on fundoscopy. Although steroid was started, but monocular blindness did not recover completely. The endovascular embolization of paraclinoid aneurysm, especially projecting superiorly with large irregular shape, has the risk of progressive visual loss because of the proximity to optic nerve.

• Natural Product Sciences
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• v.27 no.4
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• pp.300-306
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• 2021

Chronic ultraviolet (UV) radiation causes photoaging, which represents skin damage, disrupts skin barrier function, and promotes wrinkle formation. We investigated that the polysaccharide extract of an edible basidiomycetous white jelly mushroom, Tremella fuciformis, (TF-Glucan^®) exhibited statistically photoprotective activity by inhibiting matrix metalloproteases (MMPs) and increasing collagen synthesis, and an anti-inflammatory activity by inhibiting nitric oxide and pro-inflammatory cytokines at the concentrations of less than 1000 ㎍/ml, which is not cytotoxic (p < 0.05). Additionally, TF-Glucan^® increased the expression of involucrin and filaggrin to prevent the disruption of UVB-induced barrier function (p < 0.05). TF-Glucan^® was assessed as a safe material by the human primary skin irritation (1, 3, 5%), human repeated insult patch test (no sensitization at 5%), 3T3 NRU phototoxicity assay (no phototoxicity, PIF < 2, MPE < 0.1), eye irritation test test by BCOP (no category, IVIS ≤ 3) and local lymph node assay (negative at 10, 25, 50%) for identifying potential skin sensitizing. These results suggest that TF-Glucan^® may be useful as an anti-photoaging ingredient for developing cosmeceuticals.

• Journal of Sensor Science and Technology
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• v.33 no.2
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• pp.93-97
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• 2024

With the development of promising future mobility and urban air mobility (UAM) technologies, the demand for LIDAR sensors has increased. The SWIR photodetector is a sensor that detects lasers for the 3D mapping of lidar sensor and is the most important technology of LIDAR sensor. An SWIR photodetector based on QDs in an eye-safe wavelength band of over 1400 nm has been reported. QDs-based SWIR photodetectors can be synthesized and processed through a solution process and have the advantages of low cost and simple processing. However, the organic ligands of QDs have insulating properties that limit their ability to improve the sensitivity and stability of photodetectors. Therefore, the technology to replace organic ligands with inorganic ligands must be developed. In this study, the organic ligand of the synthesized PbS QDs was replaced with a MAPI inorganic ligand, and an SWIR photodetector was fabricated. The analysis of the characteristics of the manufactured photodetector confirmed that the photodetector based on MAPI-capped PbS QDs exhibited up to 26.5% higher responsivity than that based on organic ligand PbS QDs.

• Toxicological Research
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• v.21 no.1
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• pp.15-21
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• 2005

There is now a growing concern about the possible toxicity of heavy metals in cosmetics. Heavy metals can be used as cosmetic ingredients or may be present as low level impurities in some of the raw materials. Chromium derivatives are used as pigments in cosmetics. Chromium is essential and toxic trace elements. Chromium may cause skin allergy. However, the regulations related to cosmetic products give no limit values for Chromium. Hexavalent chromium is significantly more toxic than trivalent chromium. Hexavalent chromium may present a carcinogenic risk at high concentrations. Therefore, it is important to consider oxidation state of chromium when analyze chromium. The purpose of this study is to determine the concentrations of water-soluble trivalent and hexavalent chromium in samples of makeup products, and to assess the safety of cosmetics on the basis of animal sensitization tests using guinea pig. The present study of chromium in 48 makeup products of 12 manufacturers provides a basis for assessing safety of makeup products. Water-soluble hexavalent chromium was not detected in any product. Water-soluble trivalent chromium was detected in only 9 eye shadows out of 48 makeup products, and could not be quantified 3 out of 9 eye shadows. The highest level of water-soluble trivalent chromium was about 10 mg/kg in spite of 90,000 mg/kg of total chromium. The results of animal sensitization tests show that 200 mg/kg of trivalent chromium and 5 mg/kg of hexavalent chromium have no harmful effect. No cross-reaction among these metals was found. Accordingly, the concentrations of water-soluble chromium in makeup products seemed to be safe. The overall results indicate that chromium in cosmetics probably have no significant toxicological effects. However, It is necessary to set guidelines on the maximum permissible concentration of water-soluble chromium in cosmetics.

• International Journal of Highway Engineering
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• v.8 no.4 s.30
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• pp.1-11
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• 2006

Currently, road mobility improved from the National Road Improvement. Nevertheless delineation system is facility that enhanced driver's safety, that was set up often inconsistent or nonexistent over the road exit ramp So it judged functional investigation will be necessary. This study suggested setting type of the delineation system. That was based on a field study and reviews the legal standard of it and considering driver's cognition behavior. For the study, make a 3D-simulation and so could objectively a comparative test. Comparison variable between delineation setting type is selected conspicuity and visibility. Cased that illustrated characteristics of driver's visual cognition behavior. The experiment was used Eye Marker Recorder for measure the gaze frequency more quantitatively and objectively. And used the ANOVA analysis for significance testing between delineation setting type. A significant percent of the conspicuity analyzed types(Safe mark, Obstacle Sign, Warning Light, and Tubular Maker) in road exit ramp for recognize. And gaze frequency that measure of effectiveness of visibility are measured. On the analysis result, the visibility was significance difference between delineation setting type and visibility of types was best.

• The Korean Journal of Pain
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• v.10 no.1
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• pp.16-20
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• 1997

Background : Hemifacial spasm commonly occurs on muscles about the eye, but may also involve or spread to the entire side of the face. There are many treatment for facial spasm, such as neuro-vascular decompression, local injection of Botulium toxin, facial nerve block at stylomastoid foramen, facial nerve block with O'Brien method. The present study was aimed to investigate the effects of facial nerve block with O'Brien method. Methods : Forty five patients with hemifacial spasm were treated by facial nerve block with O'Brien method from January 1996 to February 1997 We reviewed the charts, retrospectively. Results : Sex ratio was 1:1.7(17 male : 28 female patients). Most patients were 40~60 years old. Most patients well tolerated facial nerve block. Three patients failed to respond to the facial nerve block. We repeated the procedure within one week. Among the 45 patients who received nerve block, 35 received repeated block; 7 patients received second repeat block, 2 patients received third repeat block. After successful nerve block, all patients were free of spasm for 1 to 6 months. Average spasm-free period was 3.5 months. Conclusion : Although the spasm-free period was short, these results suggest facial nerve block with O'Brien method is a safe and comfortable method for treatment of facial spasm.