• Title/Summary/Keyword: Eye irritation study

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The status of care for Soft Contact Lens and periodic examination (연성 콘택트렌즈의 관리 및 정기검사 실태)

  • Shin, Jang Cheol
    • Journal of Korean Ophthalmic Optics Society
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    • v.5 no.2
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    • pp.107-113
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    • 2000
  • This study has analyzed soft contact lens care-after-sale and periodic examinations at optical shops and eye clinics. And I wish to make that use of educational data for the soft contact lens lesson of the department of ocular optics. This questionnaire studied the status of care for soft contact lens and periodic examination, of students who wears soft contact lens. The results are as follows: First, 7.5% of students questioned wore soft contact lens. More women than men wore soft contact lens. The soft contact lens wearers purchased lens mainly at optical shops. 78.5% of them wore daily wear lens. Because of cosmetic advantages of soft contact lens. 47.9% of them wore soft contact lens. 72.5% of them wore soft contact lens less than 12 hours per a day. 32.0% of them has worn soft contact lens more than 6 months less than 1 year. 51.1% of them experienced irritation. 39.7% of them have exchanged soft contact lens between 6 and 9 months. Secondly, when purchasing lenses. 60% of soft contact lens wearers were given instructions of general care, such as duration of wearing lens, how to remove protein, how to store, and how to sterilize at both of eye clinics and optical shops. But the proportion of instructions, such as side effects and periodic examination which were given to soft contact lens wearers, is lower both at eye clinics and optical shops. Especially at optical shops, the proportion of instruction for periodic examination, is lower than at eye clinics(p<0.05). Thirdly, The proportion of operations of periodic examinations after use of soft contact lens both at eye clinics and optical shops, is low. The soft contact lens wearers have had more periodic examinations at eye clinics than at optical shops. But the rate of non-periodic examination at optical shop is 87.9%. And for periodic examinations, general care was done at optical shops. On the other hand, eye examinations, general care, and treatments were done more at eye clinics. Fourthly, 60.3% of the soft contact lens wearers understood the necessity of the periodic examinations, but actually, only 6.4% of them were given the schedule for the periodic examinations, and 2.5% of them were given at an optical shop(p<0.01).

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EYE IRRITATION TEST OF LENS WASHING AGENTS CLlWELLTM ON NEW ZEALAND WHITE RABBITS (렌즈 보존액 CLlWELLTM에 대한 안점막자극성시험)

  • Jang, Woo-Yeong;Lee, Jeong-Yeong
    • Journal of Korean Ophthalmic Optics Society
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    • v.12 no.2
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    • pp.67-78
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    • 2007
  • The eye irritant test of lens washing agent, CLIWELL$^{TM}$ was conducted using Draize methods according to KFDA Guidelines. In addition, to test the potential toxicity of test articles, the ratio of inflammatory cells and non-inflammatory epitheloid cells was also observed using smear cytology methods against ocular discharge. At sacrifice, the histopathological changes on Cornea, Iris, Retina and Sclera were also observed in all animals. Slight irritancy of cornea and conjunctiva was observed at 1, 2 and 3 days after dropping in non-washing group. The MIOI of these points are detected as 4.50, 1.67 and 0.67, respectively. In washing group, slight irritancy of cornea and conjunctiva were observed at 1 and 2 days after dropping with MIOI as 0.67, respectively. Therefore, CLIWELL$^{TM}$ was considered as non-irritating materials because the MIOI is detected below 5.00 throughout the whole experimental periods in both washing and non-washing groups and the IAOI was also detected as 4.50. Except for significant increase of the inflammatory cell ratios in ocular discharge at 1 day after dropping of non-washing group compared to that non-treated intact eyes, no meaningful changes on smear cytology of ocular discharges are observed in this study. In addition, no abnormal histopathological changes on the cornea, iris, retina and sclera were also detected in CLIWELL$^{TM}$ dropping group compared to that of non-treated intact eyes.

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Exposure Assessment on Sub-Populations of the Local Community following a Hydrofluoric Acid Accident (불산 누출사고에 따른 지역사회 구성원들의 노출평가)

  • Kim, Sunshin;Woo, Kuck-Hyeun;Yoon, Seong-Yong;Lim, Hyun-Sul;Kim, Geun-Bae;Yu, Seung-Do;Cho, Yong-Sung;Lee, Seokyong;Lee, Hyunsu;Yang, Wonho
    • Journal of Environmental Health Sciences
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    • v.41 no.1
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    • pp.1-10
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    • 2015
  • Objectives: The purpose of this study was to propose an indirect exposure assessment method using a questionnaire survey at a time when direct exposure assessment would be impossible after a chemical accident. Methods: About two weeks after an accident, a questionnaire survey was performed with 1,264 persons from the local community. Variables related to exposure were extracted from the survey contents, weighted and then graded for comparison with subjective symptoms in order to evaluate the extent of exposure. Survey items suitable for reflecting the previous exposure level during the accident were extracted, weighted and divided into quartile ranges. Subjective symptoms showed an increasing tendency with higher exposure level when compared with final exposure level (p<0.01). Results: For the relationship between the final exposure grade and subjective symptoms, as the exposure grade was increasing the rates complaining of symptom also showed an increasing tendency. However, when adjusted for demographic characteristics, there was a tendency for the eye irritation symptom to appear higher in women, and respiratory organ irritation appeared higher in smokers. Conclusions: When the problem of recall bias is considered, this study may not have completely unraveled exposure and the characteristics of the participants can affect subjective symptoms. Nevertheless, the exposure rating method of using a questionnaire showed a significant relationship with symptom level. It can be deemed that assessment of past exposure may be successfully evaluated by questionnaire in cases such as chemical accidents.

Instrumental Assessments of Sub-clinical Skin Reactions induced by Cosmetic Ingredients (화장품 원료에 의해 유도되는 미세 피부반응에 대한 기기적 평가 연구)

  • An, Sang-Mi;Lee, Mi-Young;Baek, Ji-Hwoon;Ham, Hye-In;Boo, Yong-Chool;Koh, Jae-Sook
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.38 no.1
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    • pp.43-50
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    • 2012
  • The safety of cosmetics or cosmetic ingredients on human skin is generally evaluated by visual assessment but some early subtle skin changes may not be noticed by the naked eyes. Thus, the present study was conducted to detect skin reactions induced by mildly irritating cosmetic ingredients by using a laser Doppler perfusion imager (LDPI) method that measures blood flow, a $Vapometer^{(R)}$ that measure strans epidermal water loss (TEWL), and a spectrophotometer that measures the skin color as the erythema values ($a^*$). Visual assessment showed that all tested oils and humectants except propylene glycol belong to the low skin irritation ranges (grades 0+ to 2.9+) while all tested surfactants and propylene glycol belong to the moderate-to strong-skin irritation ranges (grades 3+ to 5+). Among three instrumental methods, TEWL assessment appeared to be more sensitive than spectrophotometric or LDPI method and suitable for the detection of subtle skin response invisible to the naked eye (grades 0+ to 2.9+). Skin reactions of grade 3+ to 5+ could be detected by all three instrumental methods. In conclusion, the current study suggested that the sub-clinical skin reactions due to mild irritants contained in cosmetics can be best assessed by TEWL measurements.

Synthesis of Saccharide Nonionic Biosurfactants from Coconut Oil and Characterization of Their Interfacial Properties (코코넛 오일로부터 유래된 당계 비이온 계면활성제 합성 및 계면 특성 연구)

  • Jo, SeonHui;Lee, YeJin;Park, KiHo;Lim, JongChoo
    • Applied Chemistry for Engineering
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    • v.30 no.4
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    • pp.435-444
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    • 2019
  • In this study, two types of nonionic saccharide biosurfactants, GP-6 and GP-7, were prepared from coconut oil and the structure of resulting products was investigated by FT-IR, $^1H-NMR$ and $^{13}C-NMR$ spectrophotometer. The interfacial properties of GP-6 and GP-7 were found to be excellent from interfacial property measurements such as critical micelle concentration, static and dynamic surface tensions, interfacial tension, emulsification power, wetting property and foam stability. Detergency test evaluated by using a Terg-o-tometer showed moderately good detergency compared to that of conventional surfactants used in detergent formulations. Biodegradability, acute oral toxicity, acute dermal irritation and acute eye irritation tests revealed that both surfactants possess excellent mildness and superior environmental compatibility indicating the potential applicability to detergent products formulations. In particular, GP-6 can be considered as a strong candidate in detergent formulations since it is more surface active, mild and readily biodegradable than GP-7.

Monitoring of the Fugitive and Suspended Dust Dispersion at the Reclaimed Land and Neighboring Farms : Monitoring in Gunsan (간척지 인근 농경지에서의 비산 및 부유먼지 확산 모니터링(I) : 군산 모니터링)

  • Hwang, H.S.;Lee, I.B.;Shim, M.H.;Hong, S.W.;Seo, I.H.;Ryu, J.I.;Lee, S.K.
    • Journal of The Korean Society of Agricultural Engineers
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    • v.50 no.4
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    • pp.39-50
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    • 2008
  • A study on fugitive dust dispersion was conducted at Saemanguem reclaimed area located at the west coastal area of Jeon-buk Province Total reclaimed area is 40,100ha developed by building a 33km long sea dike through Gunsan, Gimje, and Buan. (Land: 28,300ha, Fresh Water Lake: 11,800ha) After this area was completely reclaimed in 2006, there has been high possibility of dust generation and dispersion to the neighboring area. The dust generated at the reclaimed land was composed mainly of minerals with high salinity, and it could make harmful effect on crop production as well on to human's health such as eye irritation and respiratory disease. Especially, when those aerosol particles are reached on the leaves of farm crops, the photosynthesis and respiration of the plants can be under restraint resulting in the decrease of agricultural productivity of the nearby farm areas. Furthermore, highly concentrated salty particles can directly damage the leaf cells. In this study, field experiment has been conducted to regularly measure the locally suspended dust particles and analyze how they were dispersed to the neighboring areas. The collected dust particles were analyzed to examine theirs sizes, concentrations, and components. The SPSS statistical program was also used to separate the dust concentration generated by the reclaimed land from the total dust concentration measured at the measuring locations.

Total Phenol Value in Urine for the Phenol Resin Workers (석탄산 수지 작업자의 뇨중 석탄산총량과 증상)

  • Ahn, Kyu-Dong;Kim, Doo-Hie
    • Journal of Preventive Medicine and Public Health
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    • v.19 no.2 s.20
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    • pp.224-232
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    • 1986
  • This study was conducted to evaluate health consequences of phenol resin workers for 6 weeks from February 21, to March 28, 1986. The subject population was 26 in a factory with phenol resin and control group was 30 non-exposed workers who were working in the other factory. The biological parameters chosen for this study were phenol concentration in working room-air, total phenol level in urine and BUN of phenol resin workers. The phenol concentration in working room-air and total phenol in urine were significantly correlated (r=0.791, p<0.01). The frequency of symptom and sign in phenol resin workers were higher than control group. The frequent symptom and sign were coughing, weight loss, poor appetite, headache, dyspnea, eye irritation and tinnitus, in order. Total phenol in urine was not reversed to normal range in spite of interruption of exposure for 4 days. The BUN value in blood and total phenol in urine were not correlated.

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A case of distichiasis treatment using electroepilation in a dog (개에서 전기제모술을 이용한 첩모중생의 치료 1례)

  • Myeong-Gon, Kang;Dong-Hyun, Han;Sei-Myoung, Han;Eun-Gyeom, Jung;Gyeong-Min, Kim;Shin-Ho, Lee;Yoon-Joo, Shin;Ju-Bin, Kang;Dong-Bin, Lee;Phil-Ok, Koh;Jae-Hyeon, Cho;Chung-Kil, Won;Chung-Hui, Kim
    • Korean Journal of Veterinary Service
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    • v.45 no.4
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    • pp.325-330
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    • 2022
  • Distichiasis is one of the diseases commonly encountered in companion animals, and these abnormal eyelashes cause corneal ulcers, continuous eye irritation, eye pain, glare, epiphora, foreign body sensation and can cause corneal opacity and vision loss in severe cases. In this study, an eyelash epilation needle for animals was developed and applied to a real case, and the results were observed. In a case of corneal ulcer caused by distichiasis of a 2-year-old Shih Tzu, a high-frequency surgical instrument for animals was converted into an electric epilation needle to attempt a procedure to destroy the eyelash hair follicles on the upper eyelid. A epilation needle was developed to have a diameter of 0.1 mm and a length of 4 mm at the end of the handle of DOCTANZ 400, an electrosurgical instrument for animals only. In the procedure, 2~3 mm of an epilation needle was inserted into the hair follicle, and 1 watt of electric power was applied to the hair follicle for about 5 sec. to carry out electrolysis until white bubbles were generated around the meibomian glands thereby destroying the hair follicle. As a result, no eyelashes grew any longer in the treated area indicating that the treatment was successful. It is hoped that the method developed in this study will be applied so that it will be widely used as a treatment method for distichiasis in companion animals that can be frequently seen hereafter.

Analyzing the Possibility of the Building Integrated Photovoltaic with DSC by the Case Studies (사례연구를 통한 DSC에 의한 BIPV 가능성 분석 연구)

  • Lee, Eung-Jik
    • The Journal of Sustainable Design and Educational Environment Research
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    • v.16 no.2
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    • pp.54-63
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    • 2017
  • The various colors and transparency of DSC and operability unrelated with directions greatly expand the use of BIPV, as a multi-functional composite of module. Therefore the possibility of DSC BIPV is examined by the case study and the analysis and then its applicability is examined. Most of the DSC BIPVs, which are found through a total of six case studies and analyzes in Korea and abroad, are mainly implemented with window glass and shading devices. This is related to the DSC transparency property. Improvements are due to the irritation of the eye due to the color of the red module. Therefore, it is important to take into account the color of the BIPV window depending on the use of the building and the room. Meanwhile, some colors of application model may stimulate eyes and such colors should be considered by use of buildings and rooms in the application of BIPV window. DSC BIPV has prospective diffusibility with the development of flexible module for the application of building surface.

Indoor and Outdoor Concentrations of Air Pollutants in Beauty Shops at kwangju Area

  • Son Bu-Soon;Song Mi-Ra;Yang Won-Ho;Park Jong-An
    • Journal of Environmental Science International
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    • v.15 no.2
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    • pp.101-106
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    • 2006
  • The work of hairdressers includes washing, coloring, bleaching, permanent waving, conditioning, and cutting hair. Hairdressers are subjected to a number of physical and toxicological hazards. The toxicological hazards are those resulting from exposure to a wide range of chemicals that are usually classified active processes. In this study, twenty beauty shops were selected to assess the exposure to indoor air pollutants such as VOCs and particulate matter $(PM_{10})$ during one month from September 1 to September 30, 2003. Indoor air quality of beauty shops might be worse by vehicle emissions because the beauty shops were generally located near roadways. Personal exposures to VOCs and $PM_{10}$ were related to indoor concentrations of beauty shops. According to the questionnaire, hairdressers complained of sore throat, eye irritation, and nervousness as physical symptoms. The measured mean concentrations of respiratory particulates were $30.5ng/m^3$ in indoor, $30.5ng/m^3$ in outdoor and $44.0ng/m^3$ on personal levels. The personal concentration was found higher than indoor and outdoor concentrations. The heavy metals mean concentrations were shown as indoor (Na>Zn>Cr), outdoor (Cr>Zn>Pb), and personal (Na>Cr>Zn) levels. Conclusively, customers as well as workers in the beauty shops might be highly exposed to air pollutants from indoor and outdoor sources. Therefore, proper management should be taken to improve the indoor air quality in beauty shops.