• Title/Summary/Keyword: External irradiation

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Rectal Injuries after Radiotherapy for Carcinoma of the Uterine Cervix (자궁경암(子宮頸癌) 방사선치료(放射線治療)에 의한 직장손상(直腸損傷))

  • Kim, Jung Jin
    • Radiation Oncology Journal
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    • v.1 no.1
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    • pp.103-109
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    • 1983
  • 47 out of 56 cases of intact uterine cervix cancer treated by radiation at the Hanyang University Hospital were followed 18 months or more after treatment. (7 patients died before 18 months, 2 cases lost to follow-up). Age distribution reveal 5 cases in 30's, 18 cases in 40's, 17 cases in 50's, 7 cases in 60's. Histologically, all cases were squamous cell type except one case of adenocarcinoma. 1. 45 cases were treated by combined external Co-60 irradiation and intracavitary irradiation by Cs-137 small sources. 1 case was treated by external irradiation only, and 1 case by intracavitary only. 2. Rectal injuries were observed in 13 cased (27.6%), 4 cases in Grade 1, 8 cased in Grade 2 and 1 cases in Grade 3 which needed surgical management. 3. Average intervals of rectal injury following treatment was 9.2 months varying from 5 to 15 months. 4. Relation between rectal injury and point A dose reveal 6 cases between 7000-7999 rad and 6 cases between 8000-8999 rad and 1 case above 9000 rad. Even though there is no direct relation between point A dose and rectal injury, it is expected that rectal injury increases as point A dose increase. 5. In the normal condition, rectal injury can't be attributed to one major cause. Radiation dose, small source distribution, general condition of patients, local anatomy of the individual patient, history of PID and previous surgery, all play complex roles.

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Prenatal Deaths and External Malformations Caused by X-Irradiation during the Preimplantation Period of ddy Mice (임신 ddy Mice에서 착상전기 방사선 조사에 따른 산전 사망 및 외부 기형 발현)

  • Ro, Hee-Jeong;Choi, Ihl-Bhong;Gu, Yeun-Wh
    • Radiation Oncology Journal
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    • v.16 no.3
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    • pp.233-243
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    • 1998
  • Purpose : To evaluate the effects of X-irradiation on prenatal deaths, i.e., preimplantation deaths, embryonic deaths and fetal deaths, and on external malformations in precompacted preimplantation ddy mice Materials and Methods : Pregnant mice (n=85) obtained by limiting the mating time to from 6 to 9 A.M., were segregated into 11 groups. The first five groups (n=26) were irradiated with X-ray doses of 0.1 0.5, 0.75, 1.5, and 3 Gy, respectively, at 24 h post conception (p.c.) of the preimplantation Period. The second five (n=27) groups were irradiated at the same X-ray doses, respectively, but at 48 h p.c. of the preimplantation period. The last group (n=32) was the control group. The uterine contents were examined on the 18th day of gestation for prenatal deaths and external malformations. Results : 1) A statistically significant increase in preimplantation deaths with increasing dose was observed in the experimental groups irradiated at 24 h p.c. and in the groups irradiated at 48 h p.c., as compared to the control group. The threshold dose was close to 0.05 Gy and 0.075 Gy for the irradiations at 24 h p.c. and 48 h p.c. respectively. 2) A statistically significant increase in embryonic deaths with increasing dose was observed in all irradiation groups, except the group irradiated with a dose of 0.1 Gy at 48 h p.c.. 3) No fetal deaths were found in any experimental group. 4) In the experimental groups irradiated at 24 h p.c. anomalies increased with statistical significance, as compared with the control group : 2 exencephalies, 2 open eyelids, 3 anophthalmias, 2 cleft Palates, 2 gastroschisis, 1 abdominal wall defect. 1 leg defect, and 2 short tail anomalies: the threshold dose for external malformations was close to 0.2 Gy at 24 h p.c.. In the groups irradiated at 48 h p.c., 1 open eyelid and 2 short tail anomalies were observed, but there was no statistical significance in those malformations. Conclusion : The results of this study reveal that X-irradiation of precompacted preimplantation ddy mice causes not only preimplantation deaths and embryonic deaths but also external malformations. In addition, external malformations were observed in our experiments at diagnostic doses, including 0.1 and 0.5 Gy. For this reason, we recommend that irradiation should be avoided during the preimplantation period by applying Rugh's 10-day rule.

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Evaluation of Endcap Welding Test for a Nuclear Fuel Rod having External and Internal Tube Structure (내외부 이중튜브구조를 갖는 핵연료봉의 봉단마개 용접시험 평가)

  • Kim, Soo-Sung;Kim, Jong-Hun;Kim, Hyung-Kyu
    • Proceedings of the KSME Conference
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    • 2008.11a
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    • pp.1377-1380
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    • 2008
  • An irradiation test of a nuclear fuel rod having external and internal tube structure was planned for a performance. To establish fabrication process satisfying the requirements of irradiation test, micro-TIG welding system for fuel rods was developed, and preliminary welding experiments for optimizing process conditions of fuel rod was performed. Fuel rods with 15.9mm diameter and 0.57mm wall thickness of cladding tubes and end caps have been used and optimum conditions of endcap welding have been selected. In this experiment, the qualification test was performed by tensile tests, helium leak inspections, and metallography examinations to qualify the endcap welding procedure. The soundness of the welds quality of a dual cooled fuel rods has been confirmed by mechanical tests and microstructural examinations.

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Effects of Cobalt-60 γ Irradiation on the Growth of Rabbits (Cobalt-60 gamma 선(線) 조사(照射)가 가토(家兎)의 성장(成長)에 미치는 영향(影響))

  • Sung, Jai Ki
    • Korean Journal of Veterinary Research
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    • v.12 no.1
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    • pp.1-5
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    • 1972
  • In oder to investigate the effects of cobalt-60 gamma ray irradiation on the body gains of rabbits aging approximately 50-day-old rabbits were subjected to single whole-body gamma irradiation externally. The results obtained were as follows: 1. There were significant differences of the body gains between control and treated groups except the 100 rads gamma-rays exposure group. 2. There were no differences in body gains between male and female rabbits. 3. Generally, the relation between gamma irradiated doses and the growth rates of rabbits were inversly proportional. 4. The $LD_{50}$ of the rabbits was 600 rads in case of single external whole-body gamma irradiation.

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P-V Characteristics According to the Irradiation (일사량에 따른 전압-전력 특성)

  • Park, Chul-Woong;Shin, Hyun-Mahn;Cho, Jae-Chul;Choi, Yong-Sung;Lee, Kyung-Sup
    • Proceedings of the KIEE Conference
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    • 2009.07a
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    • pp.2154_2155
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    • 2009
  • Development of renewable energy is promoted to achieve sustainability. So researchers are seeking and developing a new, clean, safe and renewable energy. However, solar energy is an extreme intermittent and inconstant energy source. In order to improve the photovoltaic system efficiency and utilize the solar energy more fully, and the DC power vary with the irradiation, it is necessary to study the characteristics of P-V according to the external factors. This paper presents the analysis of characteristics of P-V according to the irradiation. The results show that the DC power of the photovoltaic system are increased along with the increasing values of irradiation.

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I-V Characteristics According to the Irradiation (일사량에 따른 전압-전류 특성)

  • Hwang, Jun-Won;Jeong, Jong-Chul;Kim, Seok-Gon;Choi, Yong-Sung;Lee, Kyung-Sup
    • Proceedings of the KIEE Conference
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    • 2009.07a
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    • pp.2103_2104
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    • 2009
  • Solar, as an ideal renewable energy, has inexhaustible, clean and safe characteristics. However, solar energy is an extreme intermittent and inconstant energy source. In order to improve the photovoltaic system efficiency and utilize the solar energy more fully, and the DC current vary with the irradiation, it is necessary to study the characteristics of photovoltaic I-V according to the external factors. This paper presents the analysis of characteristics of photovoltaic I-V according to the irradiation. The results show that the DC current of the photovoltaic system are increased along with the increasing values of irradiation.

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The Role of Postoperative External Irradiation for the Incompletely Resected Meningiomas (불완전절제된 수막종에서 수술 후 방사선치료의 역할)

  • Kim Tae-Hyun;Yang Dae-Sik;Kim Chul-Young;Choi Myung-Sun
    • Radiation Oncology Journal
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    • v.18 no.2
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    • pp.85-91
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    • 2000
  • Purpose : The aim of this study is to look for the possible efficacy of postoperative external irradiation for incompletely resected meningiomas. Methods and Materials : From August 198: to January 1997, forty-four patients with intracranial meningioma were treated by postoperative external irradiation. Of the 44 meningiomas, 18 transitional, 13 meningotheliomatous, 6 hemangiopericytic, 4 atypical, 2 fibroblastic and 1 malignant meningioma were identified. We classified all patients into two groups by the histology. The benign group was consisted of the meningotheliomatous, transitional and fibroblastic types. The malignant group was consisted of the atypical, hemangiopericytic and malignat types. In the means of surgery, 37 patients were resected incompletely and 7 patients were managed by biopsy only. After surgery, all patients were received postoperative external irradiation. Radiotherapy was deliverd using Co-60 or 4 MV photon beam to a total dose of 50 to 65 Gy (mean dose 57.4 Gy) with a 1.8 to 2 Gy per fraction. The median follow-up was 48 months (range : 21 $\~$ 101 months). Multivariate analysis of the Influence by age, sex, location, histology and radiation dose on local control has been done using Cox's proportional hazard model. Results : 5-year local control rate was 93.8$\%$ for the benign histology and 51.8$\%$ for the malignant histology (p=0.0110) and overall local control rate at 5 years was 87.4$\%$. The analysis of the prognostic factors, such as age, sex, location, and radiation dose were not significant except for the histology. Conclusion : Adjuvant postoperative external irradiation appears to be significantly improved local control in the patients with incompletely resected meningiomas.

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Dose Distribution of Rectum and Bladder in Intracavitary Irradiation (자궁경부암 강내 방사선 조사장치에 의한 직장 및 방광의 피폭선량 평가)

  • Chu S. S.;Oh W. Y.;Suh C. O.;Kim G. E.
    • Radiation Oncology Journal
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    • v.2 no.2
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    • pp.261-270
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    • 1984
  • The intrauterine irradiation is essential to achieve adequate tumor dose to central tumor mass of uterine malignancy in radiotherapy. The complications of pelvic organ are known to be directly related to radiation dose and physical parameters. The simulation radiation and medical records of 203 patients who were treated with intrauterine irradiation from Feb. 1983 to Oct. 1983, were critically analized. The physical parameters to include distances between lateral walls of vaginal fornices, longitudinal and lateral angles of tandem applicator to the body axis, the distance from the external os of uterine cervix to the central axis of ovoids were measured for low dose rate irradiation system and high dose rate remote control afterloading system. The radiation doses and dose distributions within cervical area including interesting points and bladder, rectum, according to sources arrangement and location of applicator, were estimated with personal computer. Followings were summary of study results ; 1. In distances between lateral walls of vaginal fornices, the low dose rate system showed as $4\~7cm$ width and high dose rate system showed as $5\~6cm$. 2. In horizontal angulation of tandem to body axis, the low dose rate system revealed mid position$64.6\%$, left deviation $19.2\%$and right deviation $16.2\%$. 3. In longitudinal angulation of tandem to body axis, the mid position was $11.8\%$ and anterior angulation $88.2\%$ in low dose rate system but in high dose rate system, anterior angulation was $98.5\%$. 4. Down ward displacement of ovoids below external os was only $3\%$ in low dose rate system and $66.7\%$ in high dose rate system. 5. In radiation source arrangement, the most activities of tandem and ovoid were 35 by 30 in low dose rate system but 50 by 40 in high dose rate system. 6. In low and high dose rate system, the total doses an4 TDF were 50, 70 Gy and 141, 123, including 40 Gy external irradiation. 7. The doses and TDF in interesting points Co, B, were 93, 47 Gy and 230, 73 in high dose rate system but in low doss rate system, 123, 52 Gy and 262, 75 respectively. 8. Doses and TDF in bladder and rectum were 70, 68 Gy and 124, 120 in low dose rate system, but in high dose rate system, 58, 64 Gy 98, 110 respectively, and then grades of injuries in bladder and rectum were 25, $30\%$ and 18, $23\%$ respectively.

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Olfactory Neuroepithelioma (후각신경상피세포종)

  • Moon S.R.;Lee H.S.;Shin H.S.;Kim G.E.;Suh C.O.;Loh J.K.;Choi E.C.;Kim K.M.;Hong W.P.
    • Korean Journal of Head & Neck Oncology
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    • v.6 no.1
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    • pp.34-39
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    • 1990
  • This is a retrospective analysis of 8 patients with olfactory neuroepithelioma treated by external radiation during 1981-1988. Their age ranged from 13 to 65 years. All of them were male patients. At the time of diagnosis, six patients were classified as Kadish stage C, two were stage B, and none of them were stage A. Six of eight patients treated by external irradiation, only one patient had complete surgical resection followed by postoperative irradiation. Another one patient received one course of induction chemotherapy followed by radical irradiation. Three patients developed local recurrences and five patients had distant metastasis. One patient with stage B disease who had complete surgical resection followed by postoperative irradiation was alived without evidence of disease. Seven of eight patients died of tumor, with a duration of survival ranging from 3 to 106 months.

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