• Title/Summary/Keyword: External Validation

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Development of Image Segmentation Model for Sarcopenia Diagnosis and Its External Validation (근감소증 진단을 위한 영상분할 모델 개발 및 외부검증)

  • Lee, Chung-sub;Lim, Dong-Wook;Kim, Ji-Eon;Noh, Si-Hyeong;Yu, Yeong-Ju;Kim, Tae-Hoon;Jeong, Chang-Won
    • Proceedings of the Korea Information Processing Society Conference
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    • 2022.05a
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    • pp.535-538
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    • 2022
  • 근감소증은 영양부족, 운동량 감소 그리고 노화 등으로 정상적인 근육의 양과 근력 및 근 기능이 감소하는 질환을 말한다. 근감소증은 보편적으로 유럽 근감소증 실무그룹분석(EWGSOP)에서 정의한 측정 방법을 따른다. 본 논문에서는 근감소증 진단을 위한 영상 분할 모델을 개발하고 외부검증하는 방법에 대해서 제안한다. 우리는 CT 영상에서 L3 영역을 선별하여 자동으로 근육, 피하지방, 내장지방을 분할할 수 있는 인공지능 모델을 U-Net을 사용하여 개발하였다. 또한 모델의 성능을 평가하기 위해서 분할영역의 IOU(Intersection over Union)를 계산하여 내부검증을 진행하였으며, 타 병원의 데이터를 이용하여 같은 방법으로 외부검증을 진행한 결과를 보인다. 검증 결과를 토대로 문제점과 해결방안에 대해서 고찰하고 보완하고자 했다.

Thermal-hydraulic 0D/3D coupling in OpenFOAM: Validation and application in nuclear installations

  • Santiago F. Corzo ;Dario M. Godino ;Alirio J. Sarache Pina;Norberto M. Nigro ;Damian E. Ramajo
    • Nuclear Engineering and Technology
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    • v.55 no.5
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    • pp.1911-1923
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    • 2023
  • The nuclear safety assessment involving large transient simulations is forcing the community to develop methods for coupling thermal-hydraulics and neutronic codes and three-dimensional (3D) Computational Fluid Dynamics (CFD) codes. In this paper a set of dynamic boundary conditions are implemented in OpenFOAM in order to apply zero-dimensional (0D) approaches coupling with 3D thermal-hydraulic simulation in a single framework. This boundary conditions are applied to model pipelines, tanks, pumps, and heat exchangers. On a first stage, four tests are perform in order to assess the implementations. The results are compared with experimental data, full 3D CFD, and system code simulations, finding a general good agreement. The semi-implicit implementation nature of these boundary conditions has shown robustness and accuracy for large time steps. Finally, an application case, consisting of a simplified open pool with a cooling external circuit is solved to remark the capability of the tool to simulate thermal hydraulic systems commonly found in nuclear installations.

Integration of BIM and Simulation for optimizing productivity and construction Safety

  • Evangelos Palinginis;Ioannis Brilakis
    • International conference on construction engineering and project management
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    • 2013.01a
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    • pp.21-27
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    • 2013
  • Construction safety is a predominant hindrance in in-situ workflow and considered an unresolved issue. Current methods used for safety optimization and prediction, with limited exceptions, are paper-based, thus error prone, as well as time and cost ineffective. In an attempt to exploit the potential of BIM for safety, the objective of the proposed methodology is to automatically predict hazardous on-site conditions related to the route that the dozers follow during the different phases of the project. For that purpose, safety routes used by construction equipment from an origin to multiple destinations are computed using video cameras and their cycle times are calculated. The cycle times and factors; including weather and light conditions, are considered to be independent and identically distributed random variables (iid); and simulated using the Arena software. The simulation clock is set to 100 to observe the minor changes occurring due to external parameters. The validation of this technology explores the capabilities of BIM combined with simulation for enhancing productivity and improving safety conditions a-priori. Preliminary results of 262 measurements indicate that the proposed methodology has the potential to predict with 87% the location of exclusion zones. Also, the cycle time is estimated with an accuracy of 89%.

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A Study on the Development of a MOOC Design Model

  • LEE, Gayoung;KEUM, Sunyoung;KIM, Myungsun;CHOI, Yoomi;RHA, Ilju
    • Educational Technology International
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    • v.17 no.1
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    • pp.1-37
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    • 2016
  • The purpose of this study was to develop a MOOC design model that would improve the current practice of MOOC development in Korea by specifying easy-to-use course development procedures and guiding strategies. Following Richey and Klein (2007)'s conceptual model development procedure, the first step was to perform critical review of relevant literature and observe typical MOOC development processes. As a result, the initial model was developed. The second step was to conduct the expert review with five educational technology and MOOC researchers to secure the internal validity of the model. Based on the experts' suggestions, the model was revised and once again reviewed by the same experts. This process resulted in the development of the 2nd version of model. The third step was to carry out external validation research in order to test the effectiveness, efficiency, and usability of the model. A basic model may be confirmed or corrected based on examination of its results. Consequently, the model was elaborated as the final model. In the final model, 6 procedural phases and 9 specific steps were included. The six procedural phases are: Analysis (1st Iteration), Design, Development (Course Development), Implementation, Evaluation, and Analysis (2nd Iteration), a slight variation of ADDIE model. The specific steps include: 1) Goal Setting, 2) Environment Analysis, 3) Content Design, 4) Style Design, 5) Course Development, 6) Implementation Plan, 7) Course Implementation, 8) Summative Evaluation, and 9) Need Reflection. The study concluded with suggestions for further research and application of the MOOC design model.

A Study on the Development and the Verification Experiment of ECDA Equipment (외면부식직접평가 장비 개발 및 실증 시험에 관한 연구)

  • Ryou, Young-Don;Lee, Jin-Han;Jung, Sung-Won;Park, Kyeong-Wan
    • Journal of the Korean Institute of Gas
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    • v.20 no.5
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    • pp.72-81
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    • 2016
  • When the coatings of buried steel pipelines are damaged, corrosion could be occurred on the surface of the damaged areas. Moreover the pinhole occurred by corrosion of pipelines may cause accidents due to gas leakage. To prevent these accidents, foreign countries including UK and USA have carried out coating defect detection on the buried gas pipelines by using a DCVG or a ACVG and have conducted direct assessment of pipelines through digging the ground, and if necessary, have repaired the pipelines. That is called ECDA i.e External Corrosion Direct Assessment which is regulated by NACE standards(SP 0502) and etc. In Korea, the ECDA provisions were included in KGS FS551 in 2014 when the regulations of Safety Validation in Detail for the medium-pressure piping were introduced. We have developed the equipment which can be used to detect external corrosion of the buried gas pipelines. We have also constructed pipeline test bed for empirical test of the developed equipment. In addition, we have carried out the verification experiments of the developed equipment on the test bed to demonstrate the performance of the equipment. The experiments were conducted by comparison tests of the developed equipment and other equipments which have been introduced and used in Korea. As the result, we have found the developed equipment is easier to use and has far superior performance compared to other equipment being used in Korea.

A Development and Validation of Cosmetic Container Based on L-Ascorbic Acid Oxidation Property (L-Ascorbic Acid의 산화특성에 따른 화장품 용기 개발 및 유효성 분석)

  • Yoon, Sungwook
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.39 no.2
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    • pp.149-158
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    • 2013
  • L-ascorbic acid, the representative antioxidants, has a great effect on skin whitening, collagen synthesis, and anti-aging, but has low oxidative stability during storage. Therefore, in this study, thermal and oxidation properties of L-ascorbic acid under various storage conditions (powder, aqueous phase, changes of temperature, UV-irradiation, and inflow of external air etc.) were investigated. And the storage stability of ingredient was validated in the double-spaced pouch by analysing oxidation properties under each storage conditions (powder phase and blended with essence). In oder to analyze the thermal properties, TGA, DSC, and FT-IR analysis were carried out and UV-visible spectrophotometer & redox titration were used in parallel for oxidation property analyses. From the result of experiment, L-ascorbic acid was oxidized fast when it contained lots of metallic ion, hydroxy ion in aqueous solution under high temperature, UV-irradiation & inflow external air, whereas it was not oxidized for a long time when it was stored as pure powder although it has same condition as heating up, UV-irradiation & inflow external air. Based on this result, retention period of cosmetics which is using L-ascorbic acid, less stable material in oxidation can be innovatively increased when using double-spaced pouch that is designed and produced for separating storage of active ingredients.

The Construct Validation of the OSPG-2 for Screening of the Gifted in Korean Traditional and Western Music (음악(국악) 영재성 선별을 위한 부모관찰정보지(OSPG)의 구인타당화)

  • Won, Young-Sil
    • Journal of Gifted/Talented Education
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    • v.22 no.1
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    • pp.61-85
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    • 2012
  • The OSPG(Observation Scale for Parents of the Gifted in Korean Traditional and Western Music) is one of the tools for screening of the Gifted in Korean traditional and Western music. So the validity and reliability of the OSPG has an influence on securing validity of the whole identification process. The purpose of this study is to examine the validity and reliability of the OSPG-2 that input screening processing, and to suggest systematization of identification processing for the Gifted in Korean traditional and Western Music. For the achievement of this purpose, this study administered the OSPG-2 to 261 gifted students aged between 13 and 16 in the middle or high school for the arts. To validate the OSPG-2, I analyzed items of the OSPG-2, and conducted the exploratory and confirmative factor analysis. I also examined the internal consistency. As a result of the exploratory factor analysis, I collected 40 items of the OSPG-2 finally. Furthermore, I could identify psychological construct of the Gifted in Korean traditional and Western Music. The consequence of confirmative factor analysis, the model provided good fit to observed data. As a result of reliability analysis, the internal consistency of the internal characteristic verified Cronbach's ${\alpha}$=.939, and the internal consistency of the external environmental characteristic verified Cronbach's ${\alpha}$=.887. This result of validity study reflects the fact that the OSPG-2 is a valid scale and is able to input to gifted educational field instantly.

External cross-validation of bioelectrical impedance analysis for the assessment of body composition in Korean adults

  • Kim, Hyeoi-Jin;Kim, Chul-Hyun;Kim, Dong-Won;Park, Mi-Ra;Park, Hye-Soon;Min, Sun-Seek;Han, Seung-Ho;Yee, Jae-Yong;Chung, So-Chung;Kim, Chan
    • Nutrition Research and Practice
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    • v.5 no.3
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    • pp.246-252
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    • 2011
  • Bioelectrical impedance analysis (BIA) models must be validated against a reference method in a representative population sample before they can be accepted as accurate and applicable. The purpose of this study was to compare the eight-electrode BIA method with DEXA as a reference method in the assessment of body composition in Korean adults and to investigate the predictive accuracy and applicability of the eight-electrode BIA model. A total of 174 apparently healthy adults participated. The study was designed as a cross-sectional study. FM, %fat, and FFM were estimated by an eight-electrode BIA model and were measured by DEXA. Correlations between BIA_%fat and DEXA_%fat were 0.956 for men and 0.960 for women with a total error of 2.1%fat in men and 2.3%fat in women. The mean difference between BIA_%fat and DEXA_%fat was small but significant (P < 0.05), which resulted in an overestimation of $1.2{\pm}2.2$%fat (95% CI: -3.2-6.2%fat) in men and an underestimation of $-2.0{\pm}2.4$%fat (95% CI: -2.3-7.1%fat) in women. In the Bland-Altman analysis, the %fat of 86.3% of men was accurately estimated and the %fat of 66.0% of women was accurately estimated to within 3.5%fat. The BIA had good agreement for prediction of %fat in Korean adults. However, the eight-electrode BIA had small, but systemic, errors of %fat in the predictive accuracy for individual estimation. The total errors led to an overestimation of %fat in lean men and an underestimation of %fat in obese women.

Potential Applicability of Local Resection With Prophylactic Left Gastric Artery Basin Dissection for Early-Stage Gastric Cancer in the Upper Third of the Stomach

  • Akashi, Yoshimasa;Ogawa, Koichi;Hisakura, Katsuji;Enomoto, Tsuyoshi;Ohara, Yusuke;Owada, Yohei;Hashimoto, Shinji;Takahashi, Kazuhiro;Shimomura, Osamu;Doi, Manami;Miyazaki, Yoshihiro;Furuya, Kinji;Moue, Shoko;Oda, Tatsuya
    • Journal of Gastric Cancer
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    • v.22 no.3
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    • pp.184-196
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    • 2022
  • Purpose: Total or proximal gastrectomy of the upper-third early gastric cancer (u-EGC) often causes severe post-gastrectomy syndrome, suggesting that these procedures are extremely invasive for patients without pathologically positive lymph node (LN) metastasis. This study aimed to evaluate the clinical applicability of a stomach function-preserving surgery, local resection (LR), with prophylactic left gastric artery (LGA)-basin dissection (LGA-BD). Materials and Methods: The data of patients with u-EGC (pathologically diagnosed as T1) were retrospectively analyzed. Total gastrectomy was performed in 30 patients, proximal gastrectomy in 45, and subtotal gastrectomy in 6; the LN status was evaluated assuming that the patients had already underwent LR + LGA-BD. This procedure was considered feasible in patients without LN metastases or in patients with cancer in the LGA basin. The reproducibility of the results was also evaluated using an external validation dataset. Results: Of the 82 eligible patients, 79 (96.3%) were cured after undergoing LR + LGA-BD, 74 (90.2%) were pathologically negative for LN metastases, and 5 (6.1%) had LN metastases, but these findings were only observed in the LGA basin. Similarly, of the 406 eligible tumors in the validation dataset, 396 (97.5%) were potentially curative. Tumors in the lesser curvature, post-endoscopic resection status, and small tumors (<20 mm) were considered to be stronger indicators of LR + LGA-BD as all subpopulation cases met our feasibility criteria. Conclusions: More than 95% of the patients with u-EGC might be eligible for LR + LGA-BD. This function-preserving procedure may contribute to the development of u-EGC without pathological LN metastases, especially for tumors located at the lesser curvature.

Deep Learning-Enabled Detection of Pneumoperitoneum in Supine and Erect Abdominal Radiography: Modeling Using Transfer Learning and Semi-Supervised Learning

  • Sangjoon Park;Jong Chul Ye;Eun Sun Lee;Gyeongme Cho;Jin Woo Yoon;Joo Hyeok Choi;Ijin Joo;Yoon Jin Lee
    • Korean Journal of Radiology
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    • v.24 no.6
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    • pp.541-552
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    • 2023
  • Objective: Detection of pneumoperitoneum using abdominal radiography, particularly in the supine position, is often challenging. This study aimed to develop and externally validate a deep learning model for the detection of pneumoperitoneum using supine and erect abdominal radiography. Materials and Methods: A model that can utilize "pneumoperitoneum" and "non-pneumoperitoneum" classes was developed through knowledge distillation. To train the proposed model with limited training data and weak labels, it was trained using a recently proposed semi-supervised learning method called distillation for self-supervised and self-train learning (DISTL), which leverages the Vision Transformer. The proposed model was first pre-trained with chest radiographs to utilize common knowledge between modalities, fine-tuned, and self-trained on labeled and unlabeled abdominal radiographs. The proposed model was trained using data from supine and erect abdominal radiographs. In total, 191212 chest radiographs (CheXpert data) were used for pre-training, and 5518 labeled and 16671 unlabeled abdominal radiographs were used for fine-tuning and self-supervised learning, respectively. The proposed model was internally validated on 389 abdominal radiographs and externally validated on 475 and 798 abdominal radiographs from the two institutions. We evaluated the performance in diagnosing pneumoperitoneum using the area under the receiver operating characteristic curve (AUC) and compared it with that of radiologists. Results: In the internal validation, the proposed model had an AUC, sensitivity, and specificity of 0.881, 85.4%, and 73.3% and 0.968, 91.1, and 95.0 for supine and erect positions, respectively. In the external validation at the two institutions, the AUCs were 0.835 and 0.852 for the supine position and 0.909 and 0.944 for the erect position. In the reader study, the readers' performances improved with the assistance of the proposed model. Conclusion: The proposed model trained with the DISTL method can accurately detect pneumoperitoneum on abdominal radiography in both the supine and erect positions.