• Computers and Concrete
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• 제25권3호
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• pp.205-214
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• 2020

Cytoskeleton components in living cell bear large compressive force and are responsible in maintaining the cell shape. Actually these filaments are surrounded by viscoelastic media within the cell. This surrounding, viscoelastic media affects the buckling behavior of these filaments when external force is applied on these filaments by exerting continuous pressure in opposite directions to the incipient buckling of the filaments. In this article a mechanical model is applied to account the effects of this media on the buckling behavior of intermediate filaments network of cytoskeleton. The model immeasurably associates; filament's bending rigidity, adjacent system elasticity, and cytosol viscosity with buckling wavelength, buckling growth rate and buckling amplitude of the filaments.

• 한국마이크로전자및패키징학회:학술대회논문집
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• 한국마이크로전자및패키징학회 2002년도 추계기술심포지움논문집
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• pp.91-95
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• 2002

본 연구에서는 LTCC(Low temperature co-firing ceramic) 기술을 기반으로 한 적층 공정을 이용하여 최근 시장 수요가 증가하고 있는 2.4 GHz ISM(Industral science and medical) 대역의 대역통과 필터를 제작하였다. 또한 제안된 설계방식은 2.0$\times$l.2$\times$0.8㎣ 사이즈의 초소형 필터의 구현이 가능케 하였다. λ/4 공진기의 한쪽에 부하 캐패시터를 적절히 형성시켜 공진기의 길이를 짧게 하는 효과와 더불어 공진기의 Q값과 저지대역 감쇄특성을 향상시킬 수 있었다. 제안된 필터는 결합 스트립 공진기의 커플링 계수와 외부단자 Q값을 요구 사양에 맞게 최적화하여 이를 3차원 구조로 설계되었다. 제작된 대역통과 필터는 시뮬레이션을 통한 설계값과 매우 유사한 경향성을 보여주었다.

• 한국미생물·생명공학회지
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• 제46권1호
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• pp.29-39
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• 2018

Vibrio vulnificus needs various responsive mechanisms to survive and transmit successfully in alternative niches of human and marine environments, and to ensure the acquisition of steady energy supply to facilitate such unique life style. The bacterium had genetic constitution very different from that of Escherichia coli regarding metabolism of glycogen, a major energy reserve. V. vulnificus accumulated more glycogen than other bacteria and at various levels according to culture medium and carbon source supplied in excess. Glycogen was accumulated to the highest level in Luria-Bertani (3.08 mg/mg protein) and heart infusion (4.30 mg/mg protein) complex media supplemented with 1% (w/v) maltodextrin at 3 h into the stationary phase. Regarding effect of carbon source, more glycogen was accumulated when maltodextrin (2.34 mg/mg protein) was added than when glucose or maltose (0.78.1-14 mg/mg protein) was added as an excessive carbon source to M9 minimal medium, suggesting that maltodextrin metabolism might affect glycogen metabolism very closely. These results were supported by the analysis using the malP (encoding a maltodextrin phosphorylase) and malQ (encoding a 4-${\alpha}$-glucanotransferase) mutants, which accumulated much less glycogen than wild type when either glucose or maltodextrin was supplied as an excessive carbon source, but at different levels (3.1-80.3% of wild type glycogen). Therefore, multiple pathways for glycogen metabolism were likely to function in V. vulnificus and that responding to maltodextrin might be more efficient in synthesizing glycogen. All of the glycogen samples from 3 V. vulnificus strains under various conditions showed a narrow side chain length distribution with short chains (G4-G6) as major ones. Not only the comparatively large accumulation volume but also the structure of glycogen in V. vulnificus, compared to other bacteria, may explain durability of the bacterium in external environment.

• 한국해양공학회지
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• 제35권4호
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• pp.266-272
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• 2021

Mooring systems are among the most important elements employed to control the motion of floating offshore structures on the sea. Considering the use of polymer material, a new method is proposed to address the creep characteristics rather than the method of using a tension load cell for measuring the tension of the mooring line. This study uses a synthetic mooring rope made from a polymer material, which usually consists of three parts: center, eye, and splice, and which makes a joint for two successive ropes. We integrate the optical sensor into the synthetic mooring ropes to measure the rope tension. The different structure of the mooring line in the longitudinal direction can be used to measure the loads with the entire mooring configuration in series, which can be defined as SMART (Smart Mooring and Riser Truncation) mooring. To determine the characteristics of the basic SMART mooring, a SMART mooring with a diameter of 3 mm made of three different polymer materials is observed to change the wavelength that responds as the length changes. By performing the longitudinal tension experiment using three different SMART moorings, it was confirmed that there were linear wavelength changes in the response characteristics of the 3-mm-diameter SMART moorings. A 54-mm-diameter SMART mooring is produced to measure the response of longitudinal tension on the center, eye, and splice of the mooring, and a longitudinal tension of 100 t in step-by-step applied for the Maintained Test and Fatigue Cycle Test is conducted. By performing a longitudinal tension experiment, wavelength changes were detected in the center, eye, and splice position of the SMART moorings. The results obtained from each part of the installed sensors indicated a different strain measurement depending on the position of the SMART moorings. The variation of the strain measurement with the position was more than twice the result of the difference measurement, while the applied external load increased step-by-step. It appears that there is a correlation with an externally generated longitudinal tensional force depending on the cross-sectional area of each part of the SMART mooring.

• 품질경영학회지
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• 제18권2호
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• pp.9-17
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• 1990

This paper deals with a FOQ( ; fixed-order quantity) model for spare-part inventory control. In a spare-part inventory problem, stock depletion arises not from external market demand but from internal demand resulting from failures of parts in use. The problem differs from the classical inventory problem in that the demand for a failed part never arises more during stockout period, since the unit remains inoperative when stockout occurs until the failed part is replaced by new one. In the problem under consideration, n identical units are operating simultaneously and failed one is replaced immediately by new one if on-hand spares remain. In order to replenish spares, an order with quantity Q is placed whenever the number of on-hand spares falls to levels. The average annual cost of operating the spare-part inventory system is derived under the assumption that both lifetime of a part and replenishment lead-time distributions are exponential.

• 한국소음진동공학회논문집
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• 제20권8호
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• pp.710-716
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• 2010

This note represents a new disturbance observer to reduce effects of external disturbances. In case of conventional disturbance observers, additional stabilizing filters, so-called Q-filter, should be used because the conventional ones don't guarantee stability. But, the proposed one doesn't need the stabilizing filter, which is a fundamentally different research result from previous methods. Experimental verifications show this approach is realizable and valid to enhance precise positioning.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 1999년도 춘계종합학술대회
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• pp.307-312
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• 1999

결합형 유한요소-경계요소 기법을 사용하여 압전체 유연형 쏘나 변환기를 시뮬레이션하였다. 쏘나 변환기의 역학적 구동을 3차원적으로 모델링하였고 전기적 외부 부하 조건을 가지고 분석하였다. 정상 상태 변위 모드와 방향 패턴과 같은 결과들을 보여준다. 본 논문의 술통 형태의 압전 재질 쏘나 변환기는 유연형 변위를 발생시키며, 다른 형태의 쏘나 변환기와 달리 고출력, 낮은 Q-factor, 향상된 전방위성을 가지도록 해준다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 1998년도 추계학술대회 논문집
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• pp.179-182
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• 1998

The structural changes of molecules on the water surface were measured by displacement currents and $\pi$-A isotherm. By using a theoretical equations we calculated charges($\Delta$Q) and dipole moment( $m_{z}$) of saturated fatty acids( $C_{12}$, $C_{14}$, $C_{16}$). The dynamic behavior of saturated fatty acid monolayers at the air/water interface was investigated using a displacement current-measuring technique coupled with the so called Langmuir film technique and also the dipole moment of the acids was determined.as determined.d.

• 통합자연과학논문집
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• 제10권4호
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• pp.202-208
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• 2017

Xanthine Oxidase is an enzyme, which oxidizes hypoxanthine to xanthine, and xanthine to uric acid. It is widely distributed throughout various organs including the liver, gut, lungs, kidney, heart, brain and plasma. It is involved in gout pathogenesis. Hence, in the present study, Hologram based Quantitative Structure Activity Relationship Study was performed on a series of Xanthine Oxidase antagonist named 2-(indol-5-yl) thiazole derivatives. The best HQSAR model was obtained using Atoms, Bonds, Connection, Hydrogen, Chirality and Donor Acceptor as fragment distinction parameter using hologram length 71 and 4 components with fragment size of minimum 2 and maximum 5. Significant cross-validated correlation coefficient ($q^2$= 0.563) and non cross-validated correlation coefficients ($r^2$= 0.967) were obtained. The model was then used to evaluate the six external test compounds and its $r^2{_{pred}}$ was found to be 0.798. Contribution map show that presence of propyl ring in indole thiazole makes big contributions for improving the biological activities of the compounds. We hope that our HQSAR model and analysis will be helpful for future design of xanthine oxidase antagonists.

• 통합자연과학논문집
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• 제10권4호
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• pp.209-215
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• 2017

CXC chemokine receptor 2 (CXCR2) is a prominent chemokine receptor on neutrophils. CXCR2 antagonist may reduce the neutrophil chemotaxis and alter the inflammatory response because the neutrophilic inflammation in the lung diseases is found to be largely regulated through CXCR2 receptor. Hence, in the present study, Topomer based Comparative Molecular Field Analysis (Topomer CoMFA) was performed on a series of CXCR2 antagonist named pyrimidine-5-carbonitrile-6-alkyl derivatives. The best Topomer COMFA model was obtained with significant cross-validated correlation coefficient ($q^2$ = 0.487) and non cross-validated correlation coefficients ($r^2$ = 0.980). The model was evaluated with six external test compounds and its $r^2{_{pred}}$ was found to be 0.616. The steric and electrostatic contribution map show that presence of bulkier and electropositive group around cyclopropyl ring may contribute more for improving the biological activities of these compounds. The generated Topomer CoMFA model could be helpful for future design of novel and structurally related CXCR2 antagonists.