• 한국산업정보학회논문지
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• 제13권5호
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• pp.22-28
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• 2008

본 논문에서는 전자정부 시스템의 대 국민 사용성과 효율성을 증진시키기 위한 의미기반 문서 분류 방법(CoWDC)을 제시한다. 기존 의미기반 문서분류 방법에서 많은 양의 키워드들의 계층적 컨셉들을 이용하는 것을 지양하고 사용자들이 사용하는 키워드들 간의 관계를 중심으로 문서를 분류한다. 즉, 문서의 컨텍스트(context)에 근거하여 깊고 정확한 의미를 키워드 간 관계를 분석하여 적은 양의 정보로 효율적인 문서분류를 하게 된다. 이를 위해 제안한 CoWDC(Concept Wright Document Classification) 시스템은 기존의 시소러스/온톨로지의 의존도를 줄이고 키워드 관계, 관계의 경중 고려, 상하위 개념으로 변환 등을 통한 실험과 평가가 이루어졌다. 전자정부 시스템의 구조 및 특징 분석을 통해 CoWDC 실험 결과는 대국민 서비스 향상을 위해 매우 필요함을 인지하고 이를 접목하기 위한 기술적, 정책적 제언을 제시하였다. CoWDC를 통해 의미기반 검색기술의 우수함을 입증하였고 이는 전자정부 시스템의 지식베이스 구축, 운영체제의 운용, 시소러스의 구성 등의 과정에서 체계적으로 통합 운영되어야 한다.

• Biomolecules & Therapeutics
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• 제22권3호
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• pp.176-183
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• 2014

Cognitive impairment is a result of dementia of diverse causes, such as cholinergic dysfunction and Alzheimer's disease (AD). Houttuynia cordata Thunb. (Saururaceae) has long been used as a traditional herbal medicine. It has biological activities including protective effects against amyloid beta ($A{\beta}$) toxicity, via regulation of calcium homeostasis, in rat hippocampal cells. To extend previous reports, we investigated the effects of water extracts of H. cordata herb (HCW) on tauopathies, also involving calcium influx. We then confirmed the effects of HCW in improving memory impairment and neuronal damage in mice with Ab-induced neurotoxicity. We also investigated the effects of HCW against scopolamine-induced cholinergic dysfunction in mice. In primary neuronal cells, HCW inhibited the phosphorylation of tau by regulating p25/p35 expression in $A{\beta}$-induced neurotoxicity. In mice with $A{\beta}$-induced neurotoxicity, HCW improved cognitive impairment, as assessed with behavioral tasks, such as novel object recognition, Y-maze, and passive avoidance tasks. HCW also inhibited the degeneration of neurons in the CA3 region of the hippocampus in Ab-induced neurotoxicity. Moreover, HCW, which had an $IC_{50}$ value of $79.7{\mu}g/ml$ for acetylcholinesterase inhibition, ameliorated scopolamine-induced cognitive impairment significantly in Y-maze and passive avoidance tasks. These results indicate that HCW improved cognitive impairment, due to cholinergic dysfunction, with inhibitory effects against tauopathies and cholinergic antagonists, suggesting that HCW may be an interesting candidate to investigate for the treatment of AD.

• 한국가정과학회지
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• 제5권1호
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• pp.1-13
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• 2002

The purpose of this study was to verify the effectiveness of the parent education program through play to improve the relationships between mothers and children. The subject of this study consisted of 30 mothers with 4-7 aged child attending S-day-care center located in Ik-San. In order to examine the effectiveness of the parent education program through play, two groups were divided into 15 participants each. The experimental group participated in the parent education program for total 8 sessions(2 sessions per week over the 4 weeks) while the control group didn't. The instrument were 'Maternal Affection & Control Resources Scale developed by Cho, Bok Hee(1991) and 'Teacher-Child relationship Scale' by Pinata & Steinberg. Teacher-Child relationship Scale was modified to be appropriate for use with this program. Parental acceptance level was measured by modified Parental Acceptance Scale (P.P.A.S.) by porter(1954). The data were analyzed by SPSSWIN program. The statistical methods for data analysis were frequency, t-test. paired t-test. The main results of this study were as follows : First, the mothers who participated in the parent education program through play showed improvement in affectionate attitudes than before. Second, the mothers who participated in the parent education program through play have been improved in familiarity and have been decreased in conflict of relationships of mother-child than those who did not participated in. Third, the mothers who participated in parent education program through play improve the recognition on respect to children's emotion, emotional expression right, uniqueness of children's temperament and needs to children's independency and autonomy.

• 디지털융복합연구
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• 제14권11호
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• pp.507-512
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• 2016

급변하는 현재에 미디어로 인해 변해가는 상황들에 대해 증강현실과 관련된 영상커뮤니케이션의 개념과 특징, 매체에 관하여 이론적 고찰을 시도한다. 증강현실은 무에서 유를 창조하는 것이 아니라 표현이 새로워지는 것이며, 이는 즉 인터페이스의 차이로 인한 커뮤니케이션의 구조를 변화 시키는 것이다. 이를 현재 직면하고 있는 뉴미디어 시대에 있어서 나타나는 새로운 커뮤니케이션 상황을 과거에 대한 연구로부터 현재의 이론적인 모방과 절충을 잘 접목시킨 철학자이자 미디어 이론가인 벤야민 (W.Benjamin), 마샬 맥루한 (M.McLuhan), 노르베르트 볼츠 (Norbert Bolz)와 장 보드리야르 (Jean Baudrillard) 이론으로 현재의 문화적 맥락 안에서 증강현실에 대해 고찰해 보는 것에 의의가 있다.

• 복식문화연구
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• 제17권4호
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• pp.561-574
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• 2009

Black has been the most important color of all since the ancient times when the recognition of black roused, as well as during most of the eras; and can especially be said as the main color which controlled the chronicles of fashion. The purpose of the study was to broaden the application of black color image make-up by inquiring into make-up design elemental characteristics of lines and textures, after classifying magazine illustrations and advertisement make-up images using black. The photos which made effective use of black among fashion illustrations, magazine advertisements after 2001 were classified in to each type, and make-up expression method and characteristics according to design element of each image type was analyzed. The conclusion of such study was the following. 'Erotic image' showed contrast effect between eye make-up and lip color by using pale tone or red color. 'Mannish image' emphasized form and texture of eyebrow by restraining the colors of eyelids with natural brown tone eye make-up; 'Modern image' expressed vague eyebrow to bring the sensation of the direction of eye shadow on eyelids and eye line as well as slant line to relief. 'Kitsch image' showed free and light imagery by creating unique hair style with various colors; expressing lips mostly with colors similar to skin tone or by restraining colors on lips. 'Decadence image' showed messy and foul sensation with unstandardized eye make-up and matt skin of shimmer, glossy and pale tone, also with black colored lips; 'Retro image' expressed reinterpretation of images from 1920${\sim}$1960 to contemporary styles.

• 생명과학회지
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• 제19권11호
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• pp.1666-1671
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• 2009

배추과에 있어서 SLG (S locus glycoprotein)와 SRK (S locus receptor kinase) 유전자는 자가불화합성의 인식반응에 관여한다. 또한 수화작용에 중요한 aquaporin (MOD) 유전자 역시 자가불화합성 작용에 요구된다. 본 실험은 양배추 자가화 합성(SC) 계통으로부터 SC-SLG, SC-SRK, 및 SC-MOD 유전자들을 동정하고 이들 유전자의 물리적 구조를 분석하였다. 그 결과 이들 유전자들은 기존에 보고된 유전자들과 높은 상동성을 보였고 RT-PCR에 의한 발현 해석에 있어서 정상적인 발현을 나타내었다. 이들 결과들로 부터, 자가화합 양배추 계통은 주두측 자가불화합성 유전자에 이상이 있는 것이 아니라 화분측 자가불화합성 유전자의 이상 그리고/또는 S-locus에 연쇄 되어 있지 않지만 자가불화합성에 관여하는 유전자의 변이에 의해 자가불화합성이 타파되었다고 생각된다.

• 한국환경교육학회지:환경교육
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• 제12권1호
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• pp.40-63
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• 1999

As the environmental problems are recognized as daily problems in our lives, not as issues of those who are engaged in specific professional fields, the interest in environmental education is increasing gradually. The environmental education is the one that studies the environment and its problems and seeks the solutions for them. This paper deals with how the Korean subject will include environmental education. The environmental problems are already dealt with in the Korean textbooks according to the 6th curriculum for the Korean subject. A noticeable fact is that those textbooks connect the skills for language skills with environmental education. That is, the textbooks try to improve 4 language skills (speaking, listening, reading, and writing) with the Korean data related to environment, which can be the most practical means. This tendency will be also reflected in the 7th curriculum for the Korean subject, and the means will be taken by which environmental education will be able to be implemented more effectively through a variety of learning activities. In case of speaking and listening, learning activities such as speaking of, listening to, or discussing the contents concerning environmental problems can be recommended. In case of reading and literature, learning activities such as reading articles or works concerning environmental problems. Through these learning activities the Korean education will be able to achieve the goal in the fields of knowledge, information, and autonomy or attitudes which are the goals of environmental education. If the contents of the Korean curriculum are described in detail, it can be known that the Korean subject have someting to do with knowledge, skills, and recognition more deeply. In the methods In obtain information and knowledge, it will be desirable to recognize knowledge and information indirectly through various reading data rather than to recognize knowledge and information directly. Or it will be desirable to increase the sensitivity about environmental problems through literary works. For this environmental education in the above, we need to utilize discussion or presentation-oriented leaching and learning in the Korean education. Also we need to approach environmental problems by using various teaching media. We need to emphasize the education in the affective domain, especially through expression of emotions. guidance of reactions, internalization, personification, and so on.

• 한국약용작물학회지
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• 제28권2호
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• pp.85-94
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• 2020

Background: Alzheimer's disease (AD) is caused by various factors, such as cholinergic dysfunction, regulation of neurotrophic factor expression, and accumulation of amyloid-beta. We investigated whether or not a combination of Carthamus tinctorius L. seed and Taraxacum coreanum (CT) has a protective effect on scopolamine-induced memory impairment in a mouse model. Methods and Results: Mice were orally pretreated with CT (50, 100 and 200 mg/kg/day) for 14 days, and scopolamine (1 mg/kg/day) was injected intraperitoneally before subjecting them to behavior tests. CT-administered mice showed better novel object recognition and working memory ability than scopolamine-treated control mice. In T-maze and Morris water maze tests, CT (100 and 200 mg/kg/day) significantly increased space perceptive ability and occupancy to the target quadrant, respectively. In addition, 100 and 200 mg/kg/day of CT attenuated cholinergic dysfunction through inhibition of butyryl cholinesterase in brain tissue. Furthermore, CT-administered mice showed higher cyclic adenosine monophosphate-response element-binding protein (CREB) levels and lower amyloid precursor protein (APP) levels compared to scopolamine-treated control mice. Conclusions: CT improved scopolamine-induced memory impairment through inhibition of cholinergic dysfunction, up-regulation of CREB, and down-regulation of APP. Therefore, CT could be a useful therapeutic agent for AD with protective effects on cognitive impairment.

• 한국지능시스템학회논문지
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• 제19권2호
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• pp.191-196
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• 2009

본 논문에서는 BPSO(Binary Particle Swarm Optimization)방법과 상호정보량을 이용한 속성선택기법을 제안한다. 제안된 방법은 상호정보량을 이용한 후보속성부분집합을 선택하는 단계와 BPSO를 이용한 최적의 속성부분집합을 선택하는 단계로 구성되어 있다. 후보속성부분집합 선택 단계에서는 독립적으로 속성들의 상호정보량을 평가하여 순위별로 설정된 수 만큼 후보속성들을 선택한다. 최적속성부분집합 선택 단계에서는 BPSO를 이용하여 후보속성부분집합에서 최적의 속성부분집합을 탐색한다. BPSO의 목적함수는 분류기의 정확도와 선택된 속성 수를 포함하는 다중목적함수(Multi-Object Function)을 이용하였다. 제안된 기법의 성능을 평가하기 위하여 유전자 데이터를 사용하였으며, 실험결과 기존의 방법들에 비해 우수한 성능을 보임을 알 수 있었다.

• 한국실내디자인학회논문집
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• 제17권2호
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• pp.130-139
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• 2008

We have attached importance to the values of spirit and immateriality. As the age of modernism of rationality ended, human being began to emphasize spiritual and immaterial while accepting multiplicity and diversification in the whole areas of society and culture. Hence interests have increased in another side of human spirit that was oppressed by rational, analytic, reasonable and scientific thinking, which has expanded the inner world of human being to the world of the unconscious. According to these paradigm changes, steady efforts to improve our lives better both materially and spiritually have been made in the areas of art and design. Therefore, the current study aims to examine the meaning of object expressed in space from the viewpoint of the unconscious, focusing on works of designer Philippe Starck after 2000 in which unique, preferential and liking characteristics are expressed well. Philippe Starck is a designer who connects design with our daily lives and formalizes it with creative ideas. Also the study theoretically explored the theory of the unconscious, a concept of Freudianism, based on 'Meaning of Dreams' of Freud, and explained the expressional characteristics and meaning of unconscious desire through his works by putting object in Philippe Starck's space. It aims to grope for the meaning of object as another possibility that can function as a spatial ruling element by analyzing object through expanding the extent of correlation and interpretation between human containing spiritual things and object which is the recognition subject in space of the present time, not a mere concept as substance like in the past, and expression of Starck's unconscious desire based on unconscious theory.