• Journal of Preventive Medicine and Public Health
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• v.24 no.3 s.35
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• pp.287-304
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• 1991

Tolerance to several toxic effects of cadmium, including lethality has been shown following pretreatment with cadmium and zinc. This study was designed to determine if tolerance also develops to Cd-induced hepatotoxicityandrenaltoxicity. Three groups of rats (A, B, C), each consisting of 16 rats, were studied and each group was divided into four subgroups (1, 2, 3, 4), 4 rats for each subgroup. Rats were subcutaneously pretreated with saline (A), $CdCl_2$ (0.5 mg/kg, B), and $ZnCl_2$ (13.0 mg/kg, C) during time periods of $1{\sim}6$ weeks. At the end of the period, rats were challenged with $CdCl_2$ (3.0, 6.0 and 9.0 mg/kg, ip). After giving the challenge dose, cadmium and metallothionein (MT) concentrations were determined and also observed the histologic change in liver and kidney. The concentration of cadmium in liver and kidney increased dose-dependently to the challenge dosage. These da indicate the kidney is a major target organ of chronic cadmium poisoning, and suggest that cadmium induced hepatic injury, via release of Cd-MT, may play an important role in the nephrotoxicity observed in response to long-term exposure to cadmium. In addition, histologic examination of group $A_2,\;A_3\;and\;A_4$ revealed moderate to severe cadmium toxicity, evidenced by infiltration of inflammatory cells, cell swelling, pyknosis, enlarged sinusoids and necrosis in liver, and tubule cell necrosis and degeneration in kidney. However, MT concentrations in liver and kidney were increased by the pretreatment of $CdCl_2$ and $ZnCl_2$, and their morphological findings were not significantly changed, comparing with control group. Higher MT concentration in liver and kidney observed in the pretreated groups constitutes a plausible explanation of the protective effects of pretreatment against the cadmium toxicity after challenge dosing.

• The Korean Journal of Nuclear Medicine Technology
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• v.17 no.1
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• pp.3-6
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• 2013

Purpose: The treatment of thyroid cancer patients was continuously increased. According to the increment of thyroid cancer patients, the establishment of iodine therapy site was also increased in each hospital. This treatment involves the administration of radioactive iodine, which will be given in the form of a capsule. Therefore, protections and managements for radioactive source pollution and radiation exposure should be necessary for radiation safety. Among the many problems, the problem of disposing the radioactive wastes was occurred. In this study, The date for self-disposal for radioactive wastes, which were contaminated in clothes, bedclothes and trash, were calculated. Materials and Methods: The number of iodine therapy ward was 15 in Korea Institute of Radiological Medical and Sciences. Recently, 8 therapy wards were operated for iodine therapy patients and others were on standby for emergency treatment ward of any radiation accidents. Radioactive wastes, which were occurred in therapy ward, were clothes, bedclothes, bath cover for patients washing water and food and drink which was leftover by patients. Each sample was hold into the marinelli beaker (clothes, bedclothes, bath covers) and 90 ml beaker (food, drink, and washing water). The activities of collected samples were measured by HpGe MCA device (Multi Channel Analysis, CANBERRA, USA) Results: The storage period for the each kind of radioactive wastes was calculated by equation of storage periods based on the measurement outcomes. The average storage period was 60 days for the case of clothes, and the maximum storage period was 93 days for patient bottoms. The average storage period and the maximum storage period for the trash were 69 days and 97 days, respectively. The leftover foods and drinks had short storage period (the average storage period was 25 days and maximum storage period was 39 days), compared with other wastes. Conclusion: The proper storage period for disposing the radioactive waste (clothes, bedclothes and bath cover) was 100 days by the regulation on self-disposal of radioactive waste. In addition, the storage period for disposing the liquid radioactive waste was 120 days. The current regulation for radioactive waste self-disposing was not suitable for the circumstances of each radioactive therapy facility. Therefore, it was necessary to reduce the leftover food and drinks by adequate table setting for patients, and improve the process and regulation for disposing the short-half life radioactive wastes.

• Journal of dental hygiene science
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• v.17 no.4
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• pp.358-367
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• 2017

The purpose of this study was to evaluate the influence of water infiltration and flexural strength changes in dental porcelain with glazing treatment. The block specimens were prepared as experimental materials, using feldspar type commercial dental porcelain; then, these were fired at $940^{\circ}C$ for 1 minute. The fired specimens were polished with a dimension of $40{\times}5.5{\times}5mm$. The specimens were distributed to two experimental groups: with and without glazing treatment specimens (n=5), and they were immersed in a solution of pH 7 for 3, 7, and 20 days at $40^{\circ}C$ after fabrication. To evaluate the flexural strength changes with water infiltration treatment in specimens with and without glazing, the 3-point flexural test was performed, using a universal testing machine until failure occurred. Starting powder and fired specimens consisted of amorphous and leucite crystalline phase. The Vickers hardness of fired specimens was more than 1.6 times higher than that of the enamel of natural teeth. According to porosimeter results, the specimens without glazing treatment exhibited a porosity of about 14.7%, whereas the glazed specimens exhibited the lowest porosity at about 1.1%. The average flexural strength of glazed specimens was higher than the flexural strength of specimens without glazing treatment (p<0.05). The flexural strength of all specimens with and without glazing treatment deteriorated with accelerated aging in the solution. In addition, significant differences between these two treatment groups were observed in all of the specimens treated at various water infiltration periods (p<0.05). The exposure of internal pores and micro-cracks in the surface due to polishing of the fired specimens influenced mechanical behaviors. Especially, the flexural strength in specimens without glazing treatment has shown significant degradation with the infiltration of water. Therefore, this study suggests that glazing processes can improve mechanical properties of dental porcelain.

• Journal of Korean Society for Atmospheric Environment
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• v.33 no.1
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• pp.31-44
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• 2017

The aim of this study is to evaluate the accuracy and variability of the oak pollen concentrations over the Seoul metropolitan region (SMR) simulated by the Community Multiscale Air Quality (CMAQ)-based pollen dispersion model, which is the CMAQ-pollen model integrated with the improved oak pollen emission model(PEM-oak). The PEM-oak model developed is based on hourly emission flux parameterization that includes the effects of plant-specific release, meteorological adjustment, and diurnal variations of oak pollen concentrations. A 33 day-run for oak pollen simulation was conducted by the CMAQ-pollen model with a 3 km spatial resolution for the SMR during the 2014 spring pollen season. Modeled concentrations were evaluated against the hourly measurements at three Burkard sampling sites. Temporal variations of oak concentrations were largely well represented by the model, but the quantitative difference between simulations and measurements was found to be significant in some periods. The model results also showed that large variations in oak pollen concentrations existed in time and space and high concentrations in the SMR were closely associated with the regional transport under strong wind condition. This study showed the effective application of the CMAQ-pollen modeling system to simulate oak pollen concentration in the SMR. Our results could be helpful in providing information on allergenic pollen exposure. Further efforts are needed to further understand the oak pollen release characteristics such as interannual variation of the oak pollen productivity and its spatio-temporal flowering timing.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.3 no.4
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• pp.271-275
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• 1998

Controversial observations on the effect of pre-attached bacteria on the attachment of diatoms to artificial surfaces immersed in seawater have been made. Furthermore, it is not known whether or not pre-attached bacteria on artificial surfaces influence attachment of diatoms in natural seawater. In this study, we used various surfaces to which marine bacteria were pre-attached for different incubation periods. In the first experiment, glass slides were initially attached by marine natural bacteria with different exposure time (0-133 hr) and then immersed into seawater for a certain time period. The attachment of diatoms was not affected by the abundance of pre-attached bacteria (p > 0.05). The maximum abundance of attached diatoms was found on control surfaces, and the minimum abundance on surfaces where attached bacterial abundance was highest. In the second experiment, glass slides and acryl slides, either attached by marine natural bacteria for 6 days or coated by agar, were immersed in seawater. Untreated slides were also employed. On the surfaces of acryl slides with the most abundant attached bacteria ($5.4{\pm}0.02{\times}10^5\;cells\;cm^{-2}$), abundances of attached diatoms were less than those on untreated slides. On the surfaces of glass slides with bacterial abundance of $2.5{\pm}1.0{\times}10^5\;cells\;cm^{-2}$, however, abundances of attached diatoms were not different from those of untreated slides. On the agar-coated slides, the immigration rate and immigration coefficient were on average > 2 folds compared to other surfaces, indicating high rates of diatom attachment on mucilage simulated surfaces. Therefore, it seems that pre-attachment of bacteria is not prerequisite for the attachment of diatoms on artificial surfaces.

• Journal of Embryo Transfer
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• v.16 no.1
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• pp.35-40
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• 2001

Artificial insemination (AI) with frozen or cooled semen is widely used in commercial fields of cattle and pig. Little is known about characteristics of canine sperm after freezing or cooling. For both practical and commercial goal, the canine semen treated with cooling and freezing should be carried out to exam the fundamentals, including sperm motility, survivability and fertilizing capacity. The aim of this study, thus, was to identify the effects of extended exposure to 4$0^{\circ}C$ on canine semen by motility, survivability, acrosomal changes following different duration. Fifteen ejaculates collected by digital manipulation twice per week from 3 dogs (Shih-Tzu) were divided to 16 aliquots after adding Tris-egg yolk (TE) buffer formulated by our laboratory, and cooled from 37 to 4$^{\circ}C$, by ramp rate of 0.6$^{\circ}C$/min. Each sample was evaluated by their motility, survivability and the acrosomal status at 0h (control), 2h, 12h and 1 d~10 d, respectively. The motility of spermatozoa was graded to 6 levels using the modified method of Seager. The survivability of sperm was assessed using an epifluorescence microscope after Fert/Light (Mole-cular Probes Inc.) staining. To estimate the proportion of the spermatozoa of intact acrosome, 200 spermatozoa were assessed in randomly selected fields, using epifluorescence microscope after FITC/PSA (Sigma) staining. At 2 h after cooling, the motility of most spermatozoa were assessed to be grade 0 and 1. At 12 h, high number of sperm were in grade 0 to 1, however, it was significantly (P<0.05) lower than that of 2 h. From 1 d to 4 d, ~50% of sperm was assessed to grade 0 to 1. On day 7, a little sperm were in grade 0 to 1. No sperm showed motility on day 10. Sperm motility was rapidly reduced by the percent of 10% of grade 0 to 1. From 2 h to 6 h, the number of live sperm was 90% and the sperm chilled for 10 days lived>50%. Acrosomal intact of spermatozoa exposed to 4$^{\circ}C$ for 2 h was 51%, supposed the sperm of control was 100%. Our results suggest that 1) this is easy to transfer and preservation for short periods 2) AI can be used by semen chilled for 6-Day.

• Horticultural Science & Technology
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• v.28 no.5
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• pp.902-911
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• 2010

Oriental melon ($Cucumis$ $melo$ var. $makuwa$) is a popular and high-value market fruit cultivated in Korea. Consumers are becoming increasingly interested in oriental melon as a healthy diet over the past few years. However, the melons have relatively high quality loss because the fruit are mainly produced for a limited period of time in the summer season. Lack of the proper postharvest treatments and high temperature exposure at harvest or during distribution are the most critical environmental factors limiting postharvest life of fruit. This review focuses on the overview of current research studies for postharvest treatment and functional packaging technology of oriental melon in Korea. Major physiological problems of the harvest fruit include the ripening process in quality changes of the produce such as loss of weight, firmness, flavor, and decay during the storage periods. Low temperature at 7 to $10^{\circ}C$ with high relative humidity of 90 to 95% is the suitable environmental condition used to maintain the quality of fresh oriental melon. Controlled atmosphere (CA) storage or modified atmosphere (MA) packaging can be used as supplemental treatments to extend postharvest-life. For oriental melon, an optimum CA is currently recommended to be 2-3% oxygen and 5-10% carbon dioxide atmosphere. Precooling, pretreatments of ethylene action and functional packaging system can be applied to oriental melon after harvest in order to extend storage life. Major active packaging technologies are concerned with a selectively gas permeable film related to respiration of produce and the packaging applications of ethylene removal, antimicrobial, and antifogging substances to keep the effective freshness of fruit.

• Applied Chemistry for Engineering
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• v.27 no.5
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• pp.495-501
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• 2016

Mineral oil has been widely used as an insulating oil for electrical transformers for a long time, but the necessity of employing new insulation oil such as vegetable oil has been increased due to urgent needs for the biodegradability when it leaks and also for the thermal stability at a higher operation temperature. Although specific periods are required between the production and consumption, there are still short of the data to prove the insulation oils' storage stability depending upon various circumstances and their resources. Thus, this paper demonstrates the insulation oils' oxidation characteristics of both mineral and vegetable oils when each was exposed to different environments for 12 weeks. From this test, some properties including total acid number, water content and dielectric breakdown were changed under specific conditions and resources. Vegetable oils showed higher hydrophilicity and water saturation than those of mineral oils due to their molecular compositions. Under sunlight exposure condition, all insulation oils oxidized and changed their properties when exposing to the direct light, regardless of the resource used.

• Korean Journal of Optics and Photonics
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• v.25 no.1
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• pp.38-43
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• 2014

An external cavity laser supporting two wavelengths is demonstrated by incorporating polymer waveguide Bragg reflectors and a superluminescent light-emitting diode. An oversized rib waveguide structure and Bragg gratings are designed by using the effective-index and transmission-matrix methods. Bragg gratings with different periods are inscribed on a polymer waveguide through double-exposure laser interferometry. In order to tune the cavity loss affected by the reflectivity of Bragg gratings, a Bragg reflectors with varying length is incorporated. Two-wavelength-mode lasing is achieved for the device consisting of 2-mm long, 537-nm period gratings and 2.2-mm long, 540-nm period gratings; the lasing wavelengths are 1554 nm and 1564 nm, with an output power close to 0 dBm, a 20-dB bandwidth of 0.2 nm, and a side-mode suppression ratio of 45 dB.

• Restorative Dentistry and Endodontics
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• v.12 no.1
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• pp.119-129
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• 1986

The purpose of this study was to evaluate the marginal leakage of glass ionomer cement with different cavosurface margins. 192 class V cavities were prepared on freshly extracted non-carious teeth and glass ionomer cement were inserted according to the manufacturer's instructions. Cavity preparations for this investigation were performed in four groups. The experimental specimens were made by packing the glass ionomer cement (Fuji Ionomer Type II G-C Co. Japan) into the prepared 192 cavities of four groups with different modes: Group I. - The 48 cavities with $90^{\circ}$ butt-joint cavosurface preparation and restored with glass ionomer cement. Group II. - The 48 cavities with butt-joint preparation modified by $135^{\circ}$ beveling the cavosurface in the dentin and restored with glass ionomer cement. Group III. - The 48 cavities with butt-joint preparation modified by cutting a chamfer in the dentin and restored with glass ionomer cement. Group IV. - The same 48 cavities as group I, and overfilled with glass ionomer cement beyond the cavosurface angle. And four groups above described divided into three subgroups by means of conditioning the cavity walls: Control group. - Glass ionomer cement filled in the prepared 64 cavities after being cleaned with a stream of tap water. Phosphoric acid treatment group. - Glass ionomer cement filled in the prepared 64 cavities after being conditioned with a 50% phosphoric acid. Citric acid treatment group. - Glass ionomer cement filled in the prepared 64 cavities after being conditioned with a 50% citric acid. All 192 specimens were immersed in the 2.0% basic fuchsin solution and subjected to thermal stress at one-minute intervals ($4{\pm}2^{\circ}C$ to $60{\pm}2^{\circ}C$) for 70 minutes before exposure to the dye. The specimens were sectioned ecclesiologically through the center of the restorations for different periods of immersion time, 24 hours, 7 days, 14 days 30 days. The sections were examined under a stereoscopic microscope. The results were as follows: 1. The degree of marginal leakage in group II and III was greater than that in group I and IV. 2. The degree of marginal leakage in phosphoric acid treatment group was similar with that in control group. 3. The degree of marginal leakage in citric acid treatment group was less than that in control group. 4. In all groups, the degree of marginal leakage in phosphoric acid treatment group was greater than that in citric acid treatment group. 5. There is no statistical difference of the degree of marginal leakage according to the immersion time in the dye solution.