• Title/Summary/Keyword: Exposure Diversity

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Impulse Control Disorders associated with Pramipexole/Ropinirole Use in Non-Parkinson's Disease: A Scoping Review (파킨슨 병 이외의 적응증을 가진 환자의 Pramipexole 혹은 Ropinirole 사용과 관련된 충동 조절 장애: 주제 범위 문헌 고찰)

  • Jeong, Tae hyun;Suh, Seoung Min;Song, Hyun Jin;Jeon, Nakyung
    • Korean Journal of Clinical Pharmacy
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    • v.30 no.4
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    • pp.250-258
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    • 2020
  • Background: Dopamine receptor agonists (DRAs) have been associated with impulse control disorders (ICDs) in Parkinson's disease (PD) in preliminary studies. Whether the association holds true when DRAs are used to treat non-PD, such as restless legs syndrome, prolactinoma, and several mood disorders is uncertain. Objective: The present study aimed to understand the research gaps related to the risk of ICDs associated with pramipexole or ropinirole (PRX/ROP) use as a treatment for specific underlying diseases, excluding Parkinson's disorders. Methods: We conducted a scoping review, systematically searching databases to identify literature on the types, prevalence, and factors associated with ICD in non-PD patients receiving PRX/ROP. All relevant information that helped understand the epidemiology of ICDs among non-PD patients taking PRX/ROP were extracted and analyzed. We also evaluated the potential associations between PRX/ROP and ICDs, utilizing the Naranjo scale or statistical analysis, depending on the type of literature. Results: We included 24 articles (19 case reports or case series and 5 population-based studies) in this scoping review. Evaluating the 19 case reports or case series using Naranjo scores led to the discovery of a possible link between PRX/ROP exposure and ICDs. However, important information to assess causality is frequently missing. Moreover, the population-based studies lack diversity in the study populations and enough study samples to draw conclusive results. Conclusion: Our scoping review suggests that the currently available literature requires more details in future case reports and for well-powered studies in various disease conditions where PRX/ROP is frequently used.

Examining conducting Hanbok fashion shows in the metaverse (한복 패션쇼의 메타버스 구현을 위한 탐색적 연구)

  • Eunju Park;Young-Ju Rhee
    • The Research Journal of the Costume Culture
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    • v.31 no.2
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    • pp.173-192
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    • 2023
  • This study conducted in-depth interviews with experts to implement Hanbok shows on metaverse, which can contribute to the succession and development of Hanbok design and to establish a platform that fits the reality of the Hanbok industry and consumers. In-depth interviews were conducted to collect opinions from experts, and the derived contents were divided and analyzed using an affinity diagram. Experts were positive about the use of the metaverse platform of the Hanbok show in terms of impact, accessibility, exposure, virtual fitting, issuance of NFTs, and promotion of Hanbok brands. As a result of verifying the validity of the four components of metaverse, experts highly evaluated the possibility of using Hanbok shows in the order of virtual reality, augmented reality, mirror world, and lifelogging. Visuality, influence, marketing efficiency in virtual reality, immersion in augmented reality, fantasy and artistic elements, expression, diversity, and abundant experiences were expected. The platform's requirements emphasized realistic implementation equipment and technology, collaboration between Hanbok designers and producers, in addition to government support. Results of this study showed that appropriate target was analyzed to be in the 10-30s, and the appropriate price range was found to be able to sell at a discount of 40-80% compared to offline. This study provides useful implications for the service development of metaverse content, which will also be actively used in the Hanbok field, and can be used as basic data for reviving the Korean Hanbok industry and strengthening international competitiveness.

The Impact of Global Content Experiences through OTT on Global Orientation and Global Brand Attitude (OTT를 통한 글로벌 콘텐츠 경험이 글로벌 지향성 및 글로벌 브랜드 태도에 미치는 영향)

  • Kisuk Hong;ByoungJo Kim
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.6
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    • pp.1031-1038
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    • 2023
  • In recent years, the rapid proliferation of domestic and global Over-The-Top (OTT) platforms, in conjunction with the global pandemic, has substantially enhanced the accessibility of global contents. This trend is expected to continue to strengthen. This study examines the extent to which domestic consumers experience global contents through OTT platforms and its impact on individual consumers' global identity and the formation of global brand attitudes. We conducted an empirical analysis based on a survey of university students, who constitute the main consumer group for global contents through OTT platforms. The results show that as exposure to global content s and diversity of those experiences through OTT increase, respondents exhibit higher levels of global consumer orientation and global identity. This, in turn, has a positive influence on the formation of global brand attitudes.

Metal Corrosion Mechanism by Sulfate-reducing and Iron-oxidizing Bacteria in Saline System and its Optimal Inactivation (염수계 철산화균 및 황환원균에 의한 금속 부식 및 최적 제어 방안)

  • Sung, Eun-Hae;Han, Ji-Sun;Kim, Chang-Gyun
    • Journal of Korean Society of Environmental Engineers
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    • v.30 no.8
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    • pp.798-807
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    • 2008
  • Due to economic impairment derived from metal corrosion of pumping station installed around coastal area, it was needed for related cause-effect to be investigated for understanding practical corrosion behavior and providing proper control. This research was thus carried out to determine whether the microbe can influence on metal corrosion along with its control in the laboratory. For this study, groundwater was sampled from the underground pump station(i.e. I Gas Station) where corrosion was observed. Microbial diversity on the samples were then obtained by 16S rDNA methods. From this, microbial populations showing corrosion behaviors against metals were reported as Leptothrix sp.(Iron oxidizing) and Desulfovibrio sp.(Sulfur reducing) Iron oxidizing bacteria were dominantly participating in the corrosion of iron, while sulfate reducing bacteria were more preferably producing precipitate of iron. In case of galvanized steel and stainless steel, iron oxidizing bacteria not only enhanced the corrosion, but also generated its scale of precipitate. Sulfate reducing bacteria had zinc steel corroded greater extent than that of iron oxidizing bacteria. In the inactivation test, chlorine or UV exposure could efficiently control bacterial growth. However as the inactivation intensity being increased beyond a threshold level, corrosion rate was unlikely escalated due to augmented chemical effect. It is decided that microbial corrosion could be differently taken place depending upon type of microbes or materials, although they were highly correlated. It could be efficiently retarded by given disinfection practices.

Effects of wave action and grazers on frond perforation of the green alga, Ulva australis

  • Choi, Han Gil;Kim, Bo Yeon;Park, Seo Kyoung;Heo, Jin Suk;Kim, Changsong;Kim, Young Sik;Nam, Ki Wan
    • ALGAE
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    • v.30 no.1
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    • pp.59-66
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    • 2015
  • The growth and hole formation of Ulva australis were examined at seven coastal areas of Korea between July and August, 2013. Animal species and weight growing on the Ulva fronds were estimated at Haseom, Pohang, and Woedo. The effects of wave exposure on the morphological features and residential animals of Ulva fronds were investigated at wave-exposed and sheltered sites of Seongsan on October 19, 2013. U. australis had different frond areas ($82-665cm^2$), hole areas ($2.5-6.3cm^2$), and hole numbers (9.8-41.3 holes) at the seven sites. Within $0.1m^2$ of Ulva frond, hole areas ranged from 0.37 to $5.94cm^2$, and between 4.9 and 36.2 holes were observed. Fourteen residential animal species were observed at the three evaluated sites, 75.0 (Haseom) to 408.7 individuals $100g^{-1}$ Ulva (Pohang) per site. The dominant residential species at each site differed with Amphithoe sp. at Haseom, Monodonta spp. at Pohang, and Pagurus sp. at Woedo. The growth (frond area, wet weight) and hole number of Ulva fronds, and the number of residential animals were significantly greater in samples collected from the sheltered shore than the wave-exposed shore of Seongsan. The present results showed U. australis grew well at sheltered shores and had more holes on the fronds due to abundance of residential animals. The dominant residential animals (crabs, gammaridea, and snails) were similar in the Ulva populations of sheltered and wave-exposed shores, but greater species diversity was observed at the exposed shore (18 species ver. 11 species). In conclusion, U. australis is a keystone species providing habitat to various invertebrates and frond holes are positively correlated to the number of residential animals.

Evaluating and Improving Urban Resilience to Climate Change in Local Government: Focused on Suwon (기초지자체 기후변화 대응을 위한 도시회복력 평가 및 증진방안: 수원시를 대상으로)

  • Kim, Eunyoung;Jung, Kyungmin;Song, Wonkyong
    • Journal of Environmental Impact Assessment
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    • v.27 no.4
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    • pp.335-344
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    • 2018
  • As the damage caused by the abnormal climate due to climate change is increasing, the interest in resilience is increasing as a countermeasure to this. In this study, the resilience of Suwon city was examined and the plan to improve the resilience were derived against climate impacts such as drought, heatwave, and heavy rain. Urban resilience is divided into social resilience (e.g. vulnerable groups, access to health services, and training of human resources), economic resilience (e.g. housing stability, employment stability, income equality, and economic diversity), urban infrastructure resilience (e.g.residential vulnerability, capacity to accommodate victims, and sewage systems), and ecological resilience (e.g. protection resources, sustainability, and risk exposure). The study evaluated the urban resilience according to the selected indicators in local level. In this study, the planning elements to increase the resilience in the urban dimension were derived and suggested the applicability. To be a resilient city, the concept and value of resilience should be included in urban policy and planning. It is critical to monitor and evaluate the process made by the actions in order to continuously adjust the plans.

Studies on the Effect of Environmental Pollution on the Structure of Plant Community (환경오염(環境汚染)이 식물군집(食物群集)에 미치는 영향(影響)에 관(關)한 연구(硏究))

  • Kim, Tae-Wook;Lee, Kyong-Jae;Park, In-Hyeop;Kim, Joon-Seon
    • Korean Journal of Environmental Agriculture
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    • v.2 no.1
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    • pp.35-44
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    • 1983
  • In order to elucidate the change of plant community of natural forests caused by air pollution in the area of Mt. Dosjil of Ulsan city, 25 study subplots, 5 subplots from each 5 plots were set up. These plots lay along gradients of chronic exposure to airborne sulfur dioxide ($SO_2$), fluorides(F) and possibly other pollutants. Total nitrogen, organic matter, available $P_2O_5$, and CEC were generally depressed near industrial sourecs of air pollutants. The author found a total 7 species near sources of air pollutants and 13 species at the utmost plot from air pollutants. Number of individuals, species diversity, evenness, similarity index and biomass were generally depressed near the industrial source of air pollutants. Tolerant plants to air pollution is Cyperus amuricus, Calamagrostis arundinacea, Bidens bipinnata, Cocculus trilobus, Digtaria sanguinalis, Persicaria hydropiper, Pinus thunbergii, Ambrosia artemisiifolia var. elatior, Rhododendron schlippenbachii and Robinia pseudoacacia. It contains 4.41ton/ha of aboveground biomass of Robinia pseudoacacia in damaged forest by air pollution and 39.47ton/ha of it in the non-attacked forest. The annual net production is 0.67ton/ha. yr in damaged forest and $7.73ton/ha{\cdot}yr$ in the non-attacked forest.

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Effect of Environmental Variables on the Inter- and Subtidal Macrobenthic Communities in the Iwon Dike Area (이원방조제 주변의 조간대 및 조하대 대형저서동물의 군집과 환경요인과의 관계)

  • LEE Jae-Hac;YU Ok Hwan;LEE Hyung-Gon;PARK Ja-Yang
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.37 no.4
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    • pp.295-306
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    • 2004
  • Spatial patterns in the macrobenthic community structure in the inter- and subtidal zones in front of the Iwon Dike and environmental variables were examined in August 2001, In total, 156 macrobenthic species(123 intertidal species and 90 subtidal species) were recorded during this study, predominately polychaetes $(40{\%})$, bivalves $(22{\%})$, and crustaceans $(22{\%})$. Polychaetes made up less than $40{\%}$ of the intertidal communitr, but more than $50{\%}$ of the subtidal community. The mean density during this study was $1,456ind./m^{2}.$ Multivariate analysis (multidimensional scaling) revealed significant differences in community structure among four regions: near the Iwon dike (B1), the high and middle intertidal zone (B2), low intertidal zone (Al), and subtidal zone (A2). The number of species, total density, and diversity (H') varied significantly among the four regions. The distribution of macrobenthic community was affected by environmental variables, such as ${\%}$ silt/clay content, total sulfide, lose of ignition, and chemical oxygen demand. These environmental variables were negatively correlated with the dominant species (Nephtys polybranchia, Umbonium thomasi, and Scoloplos armiger) in the intertidal area, but positively correlated with the dominant species (Lumbrineris cruzensis, Notomastus latericeus, and Moerella sp.) in the subtidal area. Environmental variables $({\%}\;silt/clay content and total sulfide)$ were positively correlated with the dominant species (Heteromastus filiformis) in region Bl, but negatively correlated with the dominant species (Umbonium thomasi and Scoloplos koreanus) in region B2. Amphipods Urothoe spp. and Monoculodes koreanus were the dominant species in region Al. Umbonium thomasi, the dominant species in region B2, was not found in regions Bl or Al. We suggest that the inter-specific competition for territory and exposure to seawater may be important factors controlling the macrobenthic community structure in the inter- and subtidal zones in front of the Iwon Dike.

Glucocorticoid Regulation of Gene Expression in Hippocampal CA3 and Dentate Gyrus (글루코코티코이드 호르몬에 의한 뇌해마의 CA와 Dentate Gyrus 부분의 유전자 발현 변화)

  • Kim, Dong-Sub;Ahn, Soon-Cheol;Kim, Young-Jin;Park, Byoung-Keun;Ahn, Yong-Tae;Kim, Ji-Youn;Kyoji, Morita;Her, Song
    • Journal of Life Science
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    • v.17 no.3 s.83
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    • pp.305-311
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    • 2007
  • Glucocorticoids (GCs) alter metabolism, synaptogenesis, apoptosis, neurogenesis, and dendritic morphology in the hippocampus. To better understand how glucocorticoids regulate these aspects of hippocampal biology, we studied gene expression patterns in the CA3 (Hippocampal pyramidal cell field CA3) and dentate gyrus (DG). Litter-matched Lewis inbred rats treated for 20 days with either 9.5 mg per day sustained-release corticosterone or placebo pellets were compared with high-density oligonucleotide microarray analysis (Rat Neurobiology U34 Arrays, Affymetrix). In placebo-treated rats, 32 genes were expressed at greater levels in CA3 than DG, whereas 3 genes were expressed at great levels in DC than CA3. Regional differences were also apparent in corticosterone-induced changes in the hippocampal transcriptome. Six genes in CA3 and 41 genes in DC were differentially regulated by corticosterone. As per the glucocorticoid effects on gene transcription in the brain, forty three of these genes were upregulated, and 4 genes were downregulated. Genes differentially expressed in hippocampus included those for 13 neurotransmitter proteins, 5 ion channel related proteins, 4 transcription factors, 3 neurotrophic factors, 1 cytokine, 1 apoptosis related protein, and 5 genes involved in synaptogenesis. Interestingly, GCs can have suppressive effects on brain BDNF mRNA transcription, one of the neurotrophic factors. These results indicate the diversity of targets affected by chronic exposure to corticosterone and highlight important regional differences in hippocampal neurobiology.

Macrobenthic community on the soft-bottom around the Youngjong Island, Korea (영종도 주변해역의 저서동물 군집)

  • LIM Hyun-Sig;LEE Jae-Hac;CHOI Jin-Woo;Je Jong-Geel
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.28 no.5
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    • pp.635-648
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    • 1995
  • Macrobenthic fauna were collected seasonally using the van Veen Grab $(0,1/m^2)$ to investigate the benthic faunal assemblages on the soft-bottoms around the Youngjong Island during October 1991 to July 1992. A total of 266 species was identified. Of these polychaetes comprised 111 species $(41.7\%)$; crustaceans $75(28.2\%)$ molluscs, $59 (22.2\%)$ and others including echinoderms, $27(7.9\%)$. Mean density and biomass were estimated to be 498 $ind./m^2$ and 54.8$g./m^2$, respectively. Polychaetes were the most dominant faunal group in terms of abundance $(332\;ind./m^2)$ and number of species as well, whereas echinoderms were predominant in biomass $(332\;g./m^2)$. The dominant species were Mediomastus sp., Heteromastus sp., Nipponomysella oblongata, and Nephts polyranchia; the abundance of these species showed seasonal variations. The study area was divided into three regions by cluster analysis based on the similarity of species composition. The first region consisted of intertidal flat (G-I); the second, shallow subtital region of muddy sand (G-II); the third, channel region of mud sediments (G-III). The intertidal flat showed the highest density, and the channel was the lowest density, but the Highest in species diversity. Distribution of macrobenthic faunal assemblages of the study area seemed to be controlled by sedimentary facies and duration of tidal exposure.

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