• 한국정보통신학회논문지
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• 제26권7호
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• pp.981-988
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• 2022

정보통신기술(ICT)를 적용한 스마트팩토리로 불리는 지능형 생산 공장은 각종 센서를 통해 공정 데이터를 실시간으로 수집하고 있다. 이렇게 수집된 데이터를 효과적으로 활용하는 연구가 많이 진행되고 있는데, 본 논문에서는 생산 공정에서 발생되는 음향 신호를 기반으로 공구 상태를 진단하는 기법을 제안한다. 첫 번째로 결함이 있는 공구를 감지할 뿐만 아니라 공회전 및 공정 운용에 따른 다양한 공구 상태를 제시한다. 두 번째로 푸리에 분석을 이용하여 사운드의 전력스펙트럼을 영상으로 표현하고, 데이터에 숨겨진 건강한 패턴을 드러내고, 강조하기 위해 일부 변형을 적용한다. 마지막으로 이렇게 획득한 대비 강화된 PSD 영상은 CNN을 이용해 상태별로 진단한다. 그 결과 제안한 음향 PSD 영상 + CNN 방법은 데이터의 차별화된 특징이 잘 반영되어 공구 상태에 따른 높은 진단 결과를 보여준다.

• 정보보호학회논문지
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• 제32권5호
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• pp.817-826
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• 2022

AI 기술이 여러 분야에 성공적으로 도입되는 추세이며, 서비스로 환경에 배포된 모델들은 지적 재산권과 데이터를 보호하기 위해 모델의 정보를 노출시키지 않는 블랙 박스 상태로 배포된다. 블랙 박스 환경에서 공격자들은 모델 출력을 이용해 학습에 쓰인 데이터나 파라미터를 훔치려고 한다. 본 논문은 딥러닝 모델을 대상으로 모델 종류에 대한 정보를 추론하는 공격이 없다는 점에서 착안하여, 모델의 구성 레이어 정보를 직접 알아내기 위해 모델의 종류를 추론하는 공격 방법을 제안한다. MNIST 데이터셋으로 학습된 ResNet, VGGNet, AlexNet과 간단한 컨볼루션 신경망 모델까지 네 가지 모델의 그레이 박스 및 블랙 박스 환경에서의 출력값을 이용해 모델의 종류가 추론될 수 있다는 것을 보였다. 또한 본 논문이 제안하는 방식인 대소 관계 피쳐를 딥러닝 모델에 함께 학습시킨 경우 블랙 박스 환경에서 약 83%의 정확도로 모델의 종류를 추론했으며, 그 결과를 통해 공격자에게 확률 벡터가 아닌 제한된 정보만 제공되는 상황에서도 모델 종류가 추론될 수 있음을 보였다.

• 한일민족문제연구
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• 제35호
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• pp.107-144
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• 2018

This paper summarizes the genealogy of post-war Zainichi magazines in Japan until 1959 and examines their meaning in the context of magazine history in Japan. The purpose of this paper is to prepare the framework to view characteristics of Zainichi magazines in Japan after the war until the present from a continuous and comprehensive perspective. Zainichi, who were left behind in Japan after the war began to project diverse aspects of their lives onto magazines. Despite the poor publishing environment, censorship of GHQ, shortage of writers and financial limitations, the Zainichi society did not give up the public sphere of magazines. The confusion in this time period acted as an element to expose limitations of Zainichi magazines in Japan. Most of magazines published in 1940s and 50s had to focus on political propaganda within the political frame, and many of such magazines were only published for a short term. In other words, it is ambiguous to define the majority of them as 'magazines' and a considerable number of them cannot even confirm the existence, making it difficult to examine the whole picture of magazines from this period. However, recently excavated materials indicate that most of Zainichi magazines in Japan attempted to reflect the reality of the Zainichi society in various ways, though they were confined in the political frame. The process in which language of magazines was changed from Korean language to Japanese and then again to Korean language suggests that Zainichi magazines in Japan tried to consistently express their existence in 'ethnicity,' 'homeland' and beyond, mediated by 'politics' and 'culture.' Moreover, the experience of seeking for the possibility of Zainichi culture in Japan from the flow of cultural movements in Japan during 1950s is an experience of seeking for a popular 'expression' that overcomes the political conflict of homeland. This reveals the diversity the Zainichi society to occur afterwards. A more precise study on individual magazines published during this period would be necessary in the future.

• 한국수정란이식학회:학술대회논문집
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• 한국수정란이식학회 2002년도 국제심포지엄
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• pp.83-83
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• 2002

The purpose of this study was to investigate the warming temperature and exposed time on the post-thaw survival rate and viability of bovine blastocyst cryopreserved by GMP vitrification. Groups of three bovine IVP blastocysts were sequentially placed into vitrification solution before being loaded into the GMP straws and immersed into LN$_2$within 20 to 25 sec. The warming rate was increased 2 times of warming temperature for improvement of post-thaw survival rates. The frozen embryos were warmed either at 35 or 70$^{\circ}C$ for 1 or 2 sec and then diluted in sucrose solution. Post-thaw blastocysts were serially washed in 0.25 and 0.15 M sucrose in holding medium (HM: TCM199 supplemented with 10% FCS) and TCM-199 for each 5 min, respectively, and then cultured in TCM199 for 24 h. The rate of re-expanded blastocyst was significantly different fer 35 and 70$^{\circ}C$ warming temporature (76.4 vs. 89.3%; P<0.05). The rate of re-expanded blastocyst at 70$^{\circ}C$ for 1 sec was significantly higher than that for 2 sec (91.1 vs. 70.9%; P<0.05). The number of nuclei counted were significantly different among control, 35 and 70$^{\circ}C$ (121${\pm}$8.5 vs. 104${\pm}$11.7 vs. 114${\pm}$10.3; P<0.05). These results indicated that the increasing of warming rate can provide high survival rates of bovine IVP blastocysts. Especially, the best viability of post-thaw blastocyst could be thaw at 70$^{\circ}C$ for 1 sec. The warming temperature and exposed time far warming was considered to be limiting factors to the viability of bovine IVP embryos. he purpose of this study was to investigate the warming temperature and expose.

• 한국임상수의학회지
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• 제39권6호
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• pp.319-325
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• 2022

Two-port laparoscopic ovariectomy (Lap-OVE) has been performed in small dogs, using 3-mm and 5-mm portal sites, and is associated with reduced surgical stress and postoperative pain. However, extension of the incision is often needed to extract the ovaries. In this study, we aimed to minimize invasiveness by using smaller-sized cannulas as well as a novel technique for ovary extraction. Lap-OVE was performed on six, healthy female dogs (range, 3 to 7.2 kg) using two 3-mm midline portals. The middle finger of a size M nitrile glove was cut at its base and sterilized preoperatively. The ovary was suspended at the body wall using a 1-0 blue nylon needle, and the ovarian pedicle and ligaments were transected using a 3-mm bipolar forceps. To facilitate the glove passing through the 3.9-mm port, it was turned inside out to expose the smooth inner surface, before being inserted into the abdominal cavity with an applicator. Both ovaries were placed inside, and the mouth of the glove was exteriorized through the port with a laparoscopic grasping forceps. The ovaries were morcellated inside the glove, using Adison-Brown tissue forceps and iris scissors, which enabled safe extraction without incision enlargement. Median incision lengths were 4.3 mm (3.5-mm cranial cannula) and 4.8 mm (3.9-mm caudal cannula). An advantage of this procedure was that there was no need for skin sutures. In conclusion, using our novel technique, sutureless Lap-OVE was possible in small dogs using two 3-mm portal sites without additional incision.

• 농업생명과학연구
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• 제50권5호
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• pp.239-249
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• 2016

농산물 직거래는 생산자와 소비자를 직접 연결하면서 중간유통비용을 절감하고 이를 통해 생산자와 소비자 모두에게 만족을 줄 수 있는 대안적인 유통경로이다. 이러한 역할때문에 최근 온라인 농산물 직거래에 대한 관심이 다시 높아지고 있다. 하지만 농산물 직거래는 중간유통단계를 생략하는 것이기 때문에 생산자가 그 역할을 대신하여야 하기에 다양한 장애요인을 가지고 있다. 본 연구에서는 직거래를 추진하고 있는 농업인을 대상으로 직거래 장애요인을 파악하고, 직거래 활성화를 위하여 농촌진흥청에서 수행하고 있는 e-비즈니스 교육을 어떤 방향으로 이끌어가야 할지에 대하여 방향을 제시하였다. 그 결과, 교육 프로그램 보완, 개인역량 강화, 협업화, 농업인들이 희망하는 교육 확대 등이 필요한 것으로 나타났다.

• 한국산업보건학회지
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• 제33권2호
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• pp.206-214
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• 2023

Objectives: To determine the effect of the various type and number of shift work on sociopsychological stress in the university hospital nurses in Seoul, South Korea. Methods: Data was collected through a self-administered questionnaire that included general characteristics, the type and number of shift work in the past 4 weeks and the an sociopsychological stress based on PWI-SF. Logistic regression analysis was conducted to analyze the effect of shift work by types on sociopsychological stress of university hospital nurses using SAS 9.4 and it adjusted general characteristics by the additional models. Results: When the number of night shift work 3 or 4 compared to 0, sociopsychological stress was significantly high(OR=2.16, 95% CI=1.29-3.65). When 5 or more, it was higher(OR=2.39, 95% CI=1.55-3.72). Two continuous night shift work compared to 0 increased sociopsychological stress(OR=2.37, 95% CI=1.49-3.81) and 3 or more even more(OR=2.70, 95% CI=1.72-4.27). If the shift work type changes 14 or 15 times compare to below 11, sociopsychological stress is increased and even higher when 15 or more times but it's not significant after adjusting for covariates. Conclusions: It suggests that workplace with nurse expose to shift work should be on lookout for more than three night shift work, more than two continuous night shift work and more than 14 shift work change which can lead to burnout, absenteeism, depression and decreased productivity.

• 분석과학
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• 제36권1호
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• pp.32-43
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• 2023

This study reports for the first time about a stability indicating RP-HPLC method for qualitative and quantitative determination of acalabrutinib in bulk and dosage form and in presence its impurities 1, 2 and 3. The chromatographic separation was carried on Zorbax XDB-C18 (250×4.6 mm; 5 µ id) as stationary phase, Phosphate buffer pH 6.4 and methanol 80:20 (v/v) as mobile phase at a flow rate of 1.0 mL/min, UV detection was carried at wavelength of 238 nm and the analysis was completed with a run time of 15 min. In these conditions the retention time of acalabrutinib and its impurities 1, 2 and 3 was observed to be 3.50, 4.83, 8.40 and 9.93 min respectively. The method was validated for system suitability, range of analysis, precision, specificity, stability and robustness. Spiked recovery at 50 %, 100 % and 150 % was carried for both standard and impurities and the acceptable % recovery of 98-102 was observed for acalabrutinib and both impurities studied and the % RSD in each spiked level was found to be less than 2. Stability tests were done through exposure of the analyte solution to five different stress conditions i.e expose to 1N hydrochloric acid, 1 N sodium hydroxide, 3 % peroxide, 80 ℃ temperature and UV radiation at 254 nm. In all the degradation condition, standard drug acalabrutinib was detected along with both the impurities studied and the degradation products were successfully separated. In the formulation analysis there is no other chromatographic detection of other impurities and formulation excipients. Hence the developed method was found to be suitable for the quantification of acalabrutinib and can separate and analyse impurities 1 and 2.

• Journal of Veterinary Science
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• 제24권4호
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• pp.53.1-53.12
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• 2023

Background: Mammalian orthoreovirus type 3 (MRV3), which is responsible for gastroenteritis in many mammalian species including pigs, has been isolated from piglets with severe diarrhea. However, the use of pig-derived cells as an infection model for swine-MRV3 has rarely been studied. Objectives: This study aims to establish porcine intestinal organoids (PIOs) and examine their susceptibility as an in vitro model for intestinal MRV3 infection. Methods: PIOs were isolated and established from the jejunum of a miniature pig. Established PIOs were characterized using polymerase chain reaction (PCR) and immunofluorescence assays (IFAs) to confirm the expression of small intestine-specific genes and proteins, such as Lgr5, LYZI, Mucin-2, ChgA, and Villin. The monolayered PIOs and three-dimensional (3D) PIOs, obtained through their distribution to expose the apical surface, were infected with MRV3 for 2 h, washed with Dulbecco's phosphate-buffered saline, and observed. Viral infection was confirmed using PCR and IFA. We performed quantitative real-time reverse transcription-PCR to assess changes in viral copy numbers and gene expressions linked to intestinal epithelial genes and antiviral activity. Results: The established PIOs have molecular characteristics of intestinal organoids. Infected PIOs showed delayed proliferation with disruption of structures. In addition, infection with MRV3 altered the gene expression linked to intestinal epithelial cells and antiviral activity, and these effects were observed in both 2D and 3D models. Furthermore, viral copy numbers in the supernatant of both models increased in a time-dependent manner. Conclusions: We suggest that PIOs can be an in vitro model to study the infection mechanism of MRV3 in detail, facilitating pharmaceutical development.

• 영어영문학
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• 제58권6호
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• pp.1119-1142
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• 2012

This article examines how Cuban-American writer Cristina García interweaves all possible experiences of Cubans through Dreaming in Cuban in terms of Bakhtin's concepts of heteroglosssia, hybridization, and the chronotope. In so doing, it reaffirms the applicability of these concepts as tools for interpreting speech genres while reevaluating and reexamining the novel in terms of Bakhtinian narratology. García identifies a sociopolitical cacophony in both America and Cuba from an open-minded perspective, striving to maintain a balance between them despite undesirable experiences with her patriotic mother and individuals in the Miami community where she worked as a journalist. In practice, she projects sociopolitical ideas onto her heroines' depictions, representing their consciousnesses in a process of interaction with others. In particular, García allows her three generations of heroines, Celia del Pino, her daughters Lourdes and Felicia, and her granddaughter Pilar Puente to live as staunchly political figures. In this way, García creates a unique novelistic situation by opposing or juxtaposing all aspects of her heroines and pitting them in a dynamic interaction with their environments. As they repeatedly tease, contradict, refute, and do battle with each other, her heroines expose various problems with the sociopolitical ideologies in both the Cuban and American contexts. García succeeds in her attempt by introducing Bakhtin's model of the "becoming" hero and depicting her heroines in dynamic interaction without her own interference. In particular, the devouring inner monologues of Pilar and her Cuban aunt Felicia are presented as the products of their extraordinarily developed self-consciousnesses, through which García attempts a multilateral approach of showing, rather than telling, her heroines' interactive inner worlds as well as introducing sociopolitical contexts. Generic factors such as epistles, diary entries, and ads copy are hybridized into Celia's and Lourdes' stories, serving the heroines' interactive contexts while filling in the many narrative gaps that result from the approach to Cuban and American history. The Bakhtinian perspective permits the interpretation that this generic hybridization enables García to cover narrative gaps resulting from the expansion of chronotopes.