• 대한물리치료과학회지
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• 제8권2호
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• pp.977-987
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• 2001

The purpose of this study was to examine the effects of sensory integration therapy (SIT) on sensory' motor development and adaptive behavior of cerebral palsy children. The design of this study was quasi experiments with a non-equivalent pre- and post-test control design. Subjects of the study were arbitrarily chosen based on predetermined selection criteria among the cerebral palsy children who were treated as out-patients at two rehabilitation hospitals one in Seoul, and the other in Kyunggi-do. The study was conducted between early April and late July in 2000. Fifteen children were in the experimental group and eleven in the control group. The allocation was done based on ease of experimental treatment. A five-step SIT program was devised from a combination of SIT programs suggested by Ayres(1985) and Finks(1989), and an author-designed SIT program for cerebral palsy children. The experimental group was subjected to 20 to 30 minutes of SIT per session. two sessions a week for ten -week period. The effects of SIT were measured with respect to 9 sub-areas that can be administered to cerebral palsy children out of a total of 17 sub-areas in the Southern California Sensory Integration Test (SCSIT) developed by Ayres (1980). In addition. the scale developed by Russell (1993) for Gross Motor Function Measure (GMFM). and Perception Motor Development Test developed by 中司利一 et al.(1987) were also applied. Adaptive behavior was analyzed using guidelines in two unpublished documents - School-Age Checklist for Occupational Therapy by the Wakefield Occupational Therapy Associates, and the OTA-Watertown Clinical Assessment by the Watertown Occupational Therapy Associates-, and an author-developed Adaptive Behavior Checklist. Collected data were statistically analyzed by SPSS PC for chi square test, Mann-Whitney test, Wilcoxon signed rank test, and paired t-test. The results were as follows: 1. In sensory development, the experimental group exhibited a score increase compared to the control group, but the difference was not statistically significant, Although the experimental group showed improvements in all. 9 sub-areas compared to the control group, only right-left discrimination exhibited statistically significant change. 2. In gross motor development, the experimental group showed improvements in score compared to the control group, but it was not statistically significant. In fine motor development, the experimental group exhibited statistically significant improvements compared to the control group. In sub-area analysis, figure synthesis showed positive change. 3. In adaptive behavior development, post-experimental adaptive behavior scores were higher compared to pre-experimental scores with statistical significance. Furthermore, sub-areas emotional behavior, perception behavior, gross-fine motor function, oral-respiration function, motor behavior, motor planning, and adaptive response exhibited higher scores after SIT. In conclusion SIT was found to be partially effective in sensory and fine motor development, effective in all adaptive behavior areas, and not effective in gross motor development. Thus, this study has shown that SIT is an effective intervention for sensory development, fine motor development, and adaptive behavior for cerebral palsy children. But, for the effectiveness of SIT on gross motor development, further studies employing longer-time experiments are recommended.

• 근관절건강학회지
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• 제6권2호
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• pp.197-210
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• 1999

Muscle stiffness, pain and discomfort in dally activities are cardinal symtoms on arthritis. To reduce these symtoms, a nonequivalent one-group pre & posttest experiment was carried out at a rural community health post area in Chonbuk province during eight weeks (from 25th of January to 20th of March, 1999). The subjects were sixteen rural old women(65-89yrs) with osteoarthritis. And to reduce the level of pain, discomfort in daily living and to increase that of life satisfaction, 30 minutes of flexibility exercise followed by $15{\sim}20\;minutes$ of local heat therapy were done three times a week. Pain scale from Arthritis Impact Measurement Scales developed by Meenan(1980) for pain, Jette's Daily Activity Discomfort Scales revised by Lee(1988) for discomfort and Life Satisfaction Scales developed by Youn(1982) for life satisfaction were used as research instruments. The data were collected by face-to-face interviews with Investigator and the experiments were done under demonstration and supervision of investigator in community health post. The data were analyzed in percentage and Wilcoxon sign rank sum test by SPSS/PC+ program. The result could be summarized as follows ; 1. The scores of experiment group who were applied hot bag followed by flexibility exercise were tended to be significant lower in the level of pain statistically(Z=4.949, P=0.0001). 2. The scores of experiment group who was applied hot bag followed by flexibility exercise were tended to be significant lower in the level of discomfort in daily living statistically(Z=2.7226, P=0.0279). 3. The scores of experiment group who was applied hot bag followed by flexibility exercise were tended to be higher in the level of life satisfaction, but there was no significant statistical difference(Z=-1.2087, P=0.2171). In conclusion, flexibility exercise with local heat therapy could be identified as an effective therapy to reduce pain and discomfort in daily living of the rural elderly with osteoarthritis. And as a community health practitioner, the investigator concluded that this exercise with local heat therapy could be developed as a health promotion program for the rural aged people.

• 대한공업교육학회지
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• 제44권2호
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• pp.1-27
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• 2019

최근 실내건축 분야의 실무 현장이나 대학의 실내건축 교육은 3차원 스케치 소프트웨어를 활용한 공간계획능력을 필수적으로 요구하고 있지만, 현재 특성화 고등학교에서의 교육은 수작업성 실기수업과 2D CAD 중심으로 구성되어 산업계의 변화에 적절하게 대응하지 못하고 있으며, 학생들의 공간계획 능력을 향상시킬 수 있는 3차원 스케치 소프트웨어 기반 수업 프로그램이 매우 부족한 실정이다. 따라서 이 연구의 목적은 특성화 고등학교 NCS 기반 실내디자인 과목의 '주거공간 계획하기' 단원에서 3차원 스케치 소프트웨어를 활용한 수업 프로그램을 개발하고, 특성화고 수업에 적용하여 학생들의 학업성취도에 미치는 효과를 알아보는 데 있다. 이 연구에서 개발한 3차원 스케치 소프트웨어 기반 수업 프로그램은 PDIE 모형 절차에 따라 준비, 개발, 실행, 평가의 4단계를 거쳐 개발되었으며, 실험설계 모형은 이질집단 사후검사설계를 사용하였다. 실험 처치는 건설 분야 특성화 고등학교 학생들을 대상으로 실시하였고, 총 9차시의 실내디자인 교과 수업에 적용하였다. 실험 처치 후에는 인지적, 정의적, 심동적 영역에 대한 학업성취도 검사를 실시하였으며, 독립표본 t-검정을 통해 개발된 수업 프로그램에 대한 효과를 분석하였다. 이 연구에서 개발된 3차원 스케치 프로그램을 활용한 수업 프로그램은 인지적, 정의적, 심동적 영역 모두에서 기존의 수작업성 실기 수업보다 학생들의 학업성취도를 향상시키는데 효과적인 것으로 나타났다.

• 대한물리의학회지
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• 제8권4호
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• pp.505-512
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• 2013

PURPOSE: The purpose of this study applied computerized cognitive therapy and proprioception exercise to stroke patients and analyzed improvement in their changes in Electrocephalogram(EEG). METHODS: The subjects were 30 patients who were diagnosed with stroke and they were randomly selected to a proprioceptive training group(n=15), a cognitive training group(n=15). The experiment was performed for three times per week for 6 weeks and EEG was measured before and after the experiment. RESULT: Before and after the experiment in each group of experiments, the ${\alpha}$-and ${\beta}$-wave study showed significant changes but, there was no significant difference in the change between groups before and after the experiment. CONCLUSION: From the above results, the cognitive training and the proprioception training have a positive impact in stroke patients EEG changes, but it is difficult to suggest a better therapeutic interventions. However, as compared with that the cognitive training that directly involved in the cognitive and brain activation, the proprioception training have changes on brain activation. Therefore, of Clinical therapeutic interventions, the proprioception training can be presented effectively to the changes in brain activation in stroke patients.

• 대한산업공학회지
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• 제26권1호
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• pp.73-80
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• 2000

To determine the exact direction and location of the human joint in motion is crucial in developing a more accurate human model and producing a more fitting artificial joint. There have been several reports on the biomechanical analysis of the joint to determine the anatomy and movement of joints. However, all the previous researches were made in vitro study, that is, they investigated the passive movement of the joint from cadavers and the suggested location of the joint axis was difficult to make practical applications due to the lack of the direction of joint axis. Also, in many biomechanical models, each joint axis is assumed to lie horizontally or vertically to the adjacent links. Such an assumption causes inherent inaccuracy. In this study, the direction and location of the transverse elbow axis was obtained with respect to the global coordinate system whose origin is on the lateral epicondyle of the humerus. The suggested result based on the global coordinate system lying on the external landmark will be helpful to understand the information of the axis and to make an application. From the experiments conducted for five subjects, the direction and location of the elbow transverse joint was determined for each subject by the helical axis method. A statistical validation was also performed to confirm the result. Finally, the result was applied to develop a simple elbow model which is a part of the kinematic arm model. The simple elbow movement model was developed to validate the significance of the result and the kinematic arm model was able to describe the geometry of any complex linkage system. As a result, the errors incurred from the proposed model were significantly reduced when compared to the ones from the previous approach.

• Journal of the Korean Data and Information Science Society
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• 제25권6호
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• pp.1181-1193
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• 2014

현재 식품의약품안전처에서는 2008년 7월부터 $2{\times}2$ 교차설계법으로 수행된 제제간의 생물학적 동등성 입증이 실패했을 때 1회에 한하여 추가시험을 허용하고 있다. 하지만 최근 생체이용률의 변동계수가 30% 이상인 고변동성 제제가 많이 등장하면서 $2{\times}2$ 교차설계법에 의한 생물학적 동등성 시험수행에 지나치게 많은 피험자가 소요되면서 그 대안으로 $2{\times}4$ 혹은 $2{\times}3$ 교차설계법을 활용해야 하는 필요성이 증대되고 있다. 본 연구에서는 $2{\times}4$ 혹은 $2{\times}3$ 교차설계법에 기반한 제제의 생물학적 동등성 평가의 추가시험에 대한 통계적 절차를 제안하고 논의하고자 한다.

• Biomolecules & Therapeutics
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• 제27권4호
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• pp.349-356
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• 2019

Behavioral analysis in mice provided important contributions in helping understand and treat numerous neurobehavioral and neuropsychiatric disorders. The behavioral performance of animals and humans is widely different among individuals but the neurobehavioral mechanism of the innate difference is seldom investigated. Many neurologic conditions share comorbid symptoms that may have common pathophysiology and therapeutic strategy. The forced swim test (FST) has been commonly used to evaluate the "antidepressant" properties of drugs yet the individual difference analysis of this test was left scantly investigated along with the possible connection among other behavioral domains. This study conducted an FST-screening in outbred CD-1 male mice and segregated them into three groups: high performers (HP) or the active swimmers, middle performers (MP), and low performers (LP) or floaters. After which, a series of behavioral experiments were performed to measure their behavioral responses in the open field, elevated plus maze, Y maze, three-chamber social assay, novel object recognition, delay discounting task, and cliff avoidance reaction. The behavioral tests battery revealed that the three groups displayed seemingly correlated differences in locomotor activity and novel object recognition but not in other behaviors. This study suggests that the HP group in FST has higher locomotor activity and novelty-seeking tendencies compared to the other groups. These results may have important implications in creating behavior database in animal models that could be used for predicting interconnections of various behavioral domains, which eventually helps to understand the neurobiological mechanism controlling the behaviors in individual subjects.

• 대한물리의학회지
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• 제17권2호
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• pp.75-82
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• 2022

PURPOSE: This study examined the correlation between the pulmonary function and respiratory muscle strengthening training on an unstable support surface and a stable support surface in stroke patients. METHODS: The study subjects were 22 stroke patients undergoing central nervous system developmental rehabilitation treatment. After excluding six dropouts, eight people in the experimental group and eight people in the control groups were classified by random sampling. Both groups performed central nervous system developmental rehabilitation therapy and were provided a 10-minute break. The experimental group was provided with an unstable support surface using Togu, and the control group was trained to strengthen the respiratory muscle in a stable support surface. Respiratory muscle strengthening training was conducted three times per week for 20 minutes. Before and after each group of experiments, a nonparametric test Wilcoxon signed rank test, and a Mann Whitney U-test analysis were used to analyze the variations between the two groups. All statistical significance levels (α) were set at 0.05. RESULTS: Both groups showed increases in the pulmonary function but showed significant differences only in the experimental group. There was a significant difference in the peak expiratory flow between the two groups. CONCLUSION: Central nervous system development rehabilitation treatment for patients with an impaired nervous system and respiratory muscle strengthening training on unstable support surfaces are effective in improving the pulmonary function of stroke patients. Therefore, they are expected to be applied to physical therapy programs to help various functional activities.

• 한국컴퓨터정보학회논문지
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• 제16권3호
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• pp.109-119
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• 2011

가상현실 시스템에서 높은 현실감과 직관적인 시각정보의 제공이 커다란 장점임에도 불구하고, 가상공간에서의 공간제시에 있어서 거리감각이 정확하게 전달되지 않는 문제점이 있다. 특히나 건축분야와 같은 공간을 취급하는 분야에서의 공간제시에 있어서의 왜곡문제는 시급히 해결해야할 필요성이 있다. 본 논문에서는 가상현실공간에서 거리감각을 고찰함에 있어서 거리감각을 조사하는 하나의 요소로서, 피실험자에 의한 이동거리추정판단에 관한 실험을 행하였다. 가상현실공간에서의 제시정보의 부족이 거리감각의 차이를 가져온다는 가정하에 몰입형 가상현실시스템에서 다양한 영상의 투영조건하에서 이동거리추정판단을 실험적으로 조사함으로써, 가상공간을 형성하는 시스템이 제공하는 정적, 동적 영상이미지의 특성에 의한 거리감각의 변화를 규명하고자 한다. 구체적인 실험방법으로는 실재 건축물의 복도를 모델링하여, 복도의 실재공간과 모델링된 가상공간을 피실험자에게 영상으로 제시하면서 이동거리추정판단의 심리실험을 수행하였다. 실험에 이용한 모델과 같은 실재의 복도에서도 이동거리추정판단의 실험을 동시에 수행함으로써, 실재환경과 가상현실환경과의 거리감각의 차이를 비교분석하고, 그 결과 실재환경과 비교하여 몰입형 가상현실시스템에서의 거리감각이 단축이 되는 경향이 나타남을 설명한다. 나아가, 몰입형 가상현실 시스템에 있어서 거리감각이 과소평가되는 경향이 나타나는 요인을 고찰하여, 영상의 해상도를 거리감각을 형성하는 중요한 요소로 판단하고 정적, 동적 이미지의 해상도의 변화에 따른 거리감각을 규명한다.

• 대한한방부인과학회지
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• 제26권2호
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• pp.138-150
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• 2013

Objectives: To observe randomized controlled trials(RCTs) related to investigating the effects of acupoint treatments on nausea and vomiting in pregnancy to establish the basis of korean medical treatments, and suggest the problems of future clinical research. Methods: After searching for national and international papers published after 2000 and restricting the parameters to 'clinical trial', 'controlled clinical trial', 'randomized controlled trial', then comparing the subjects, methods, research tools, and results to understand the effects and re-comparing the conflicting results to assume the cause. Results: Of the 9 research papers that applied acupressure, four of them used control and experimental groups, and three(75%) research papers indicated significant reduction in vomiting and nausea, and of the seven research papers that utilized the experimental and placebo groups, five(71.4%) reported significant reducing effects. Of the four research papers the used acupuncture treatments, four research papers using control and placebo groups, two showed improvements in symptoms but did not have significant results compared to sham acupuncture groups, and two showed significant reduction of symptoms compared to the control groups. The one research paper that used electrical stimulation showed significant results in the reduction of vomiting and nausea compared to the control group. Conclusions: Acupressure and electrical stimulation showed efficacy reducing the symptoms. Acupuncture treatments did not indicate efficacy some experiments. Therefore it is thought that future acupuncture treatments should use methods that resemble actual clinical medicine to establish efficacy to produce significant results.