• Title/Summary/Keyword: Experimental variable

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Sex as an important biological variable in biomedical research

  • Lee, Suk Kyeong
    • BMB Reports
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    • v.51 no.4
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    • pp.167-173
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    • 2018
  • Experimental results obtained from research using only one sex are sometimes extrapolated to both sexes without thorough justification. However, this might cause enormous economic loss and unintended fatalities. Between years 1997 and 2000, the US Food and Drug Administration suspended ten prescription drugs producing severe adverse effects on the market. Eight of the ten drugs caused greater health risks in women. Serious male biases in basic, preclinical, and clinical research were the main reason for the problem. This mini-review will describe why and how funding organizations such as the European Commission, the Canadian Institutes of Health Research, and the US National Institutes of Health have tried to influence researchers to integrate sex/gender not only in clinical research, but also in basic and preclinical research. Editorial policies of prominent journals for sex-specific reporting will also be introduced, and some considerations in integrating sex as a biological variable will be pointed out. To produce precise and reproducible results applicable for both men and women, sex should be considered as an important biological variable from basic and preclinical research.

Modeling and Dynamic Characteristics Analysis of a Continuously Variable Damper with Electro-Hydraulic Pressure Control Valve (반능동현가장치용 전자제어식 연속가변댐퍼의 모델링 및 동특성 해석)

  • Do, Hong-Mun;Hong, Gyeong-Tae;Hong, Geum-Sik
    • Journal of Institute of Control, Robotics and Systems
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    • v.8 no.2
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    • pp.158-166
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    • 2002
  • A mathematical model and dynamic characteristics ova continuously variable damper for semi-active suspen- sion systems are investigated. After analyzing the geometry of a typical continuously variable damper, mathematical models fur individual components including piston, orifices, spring, and valves are first derived and then the flow equations for extension and compression strokes are investigated. To verify the developed mathematical model, the dynamic response of the model are simulated using MATLAB/SIMULINK and are compared with experimental results. The proposed model can be used not only for mechanical components design but also for control system design.

AC Plasma Power Supply with Variable Voltage and Variable Frequency (가변전압 가변주파수(VVVF) 교류 플라즈마 전원장치)

  • Shin Wan-Ho;Yun Kee-Pok;Jeoung Hwan-Myoung;Choi Jae-Ho
    • Proceedings of the KIEE Conference
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    • summer
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    • pp.1205-1207
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    • 2004
  • AC plasma power supply is used to control a ozone generator and a air pollution gas. AC plasma power supply is composed of power semiconductor switch devices and control board adapted SHE(Selected Harmonic Elimination) PWM method. AC plasma power supply with sinusoidal VVVF(variable voltage and variable frequency) is realized. Its output voltage range is from 0 [V] to 20[kV] and output frequency range is from 8[kHz] to 20[kHz]. Using proposed system, AC high voltage and high frequency discharge is tested in the DBD(dieletric barrier discharge) reactor, and the space distribution of a its non-thermal plasma is observed. In spite of the increasement of voltage and frequency, the proposed system have a stable operation characteristics. It is verified by the experimental results.

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A BANDWIDTH VARIABLE DIGITAL GENERATOR FOR RADAR ALTIMETER

  • Lin, Ying;Liu, Heguang;Liu, Zhiqlang;Xu, Ke;Zhang, Xuabgjyb
    • Proceedings of the KSRS Conference
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    • 2002.10a
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    • pp.484-489
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    • 2002
  • This paper concerns the design and implementation of a Bandwidth Variable Digital Chirp Generator (DCG) for the radar altimeter. A double SRAM parallel structure is used to breakthrough the upper DCG bandwidth limited by the highest clock frequency of the digital chips. An experimental system working in the waveform storage method has been implemented. We show that the bandwidth changed according to the radar altimeter's requirement and the design released the stringent speed requirement of the chips fur making a variable wide bandwidth DCG.

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An experimental study for the filling balance of the family mold (Family 금형의 충전 밸런스를 위한 실험적 연구)

  • Cha B. S.;Rhee B. O.;Park H. P.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2005.09a
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    • pp.132-140
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    • 2005
  • It is well known that the family-mold has an advantage to reduce the cost for production and mold. However, defects are frequently occurred by over packing the smaller volume cavity during molding, especially whorl the family-mold has a volumetric difference between two cavities. In this study, we confirmed the cavity-filling imbalance by the temperature and the pressure sensors, and developed a variable-runner system for the cavity-filling balance. We carried out experiments fur balancing the cavity filling in the family-mold with the variable-runner system, and confirmed a balanced cavity-filing through analyzing the temperature and pressure change in each cavity as the cross-sectional area of the runner changed. We also examined the influence of the injection-speed to the balancing-capability of the variable-runner system in the experiment.

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The Control of Superheat and Capacity for a Variable Speed Refrigeration System Based on PI Control Logic

  • Hua, Li;Jeong, Seok-Kwon
    • International Journal of Air-Conditioning and Refrigeration
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    • v.15 no.2
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    • pp.54-60
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    • 2007
  • In this paper, we suggest the high efficient control method based on general PI control law for a variable speed refrigeration system. In the variable speed refrigeration system, the capacity and the superheat are mainly controlled by an inverter and an electronic expansion valve, respectively, for saving energy and improving coefficient of performance. Thus, we proposed a decoupling model to eliminate the interfering loop between the capacity and superheat at first. Next, we designed PI controller to control the capacity and superheat independently and simultaneously. Finally, the control performance was investigated through some experiments. The experimental results showed that the proposed PI controller based on the decoupling model can obtain good control performance under the various control references and thermal load.

An Experimental Study on Variable-Speed Control of an Ground-Water Circulation Pump for a Ground Source Multi-Heat Pump System (주거용 건물 지열원 멀티 히트펌프시스템의 지열순환펌프 가변유량제어에 관한 실증연구)

  • Song, Suwon
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.25 no.8
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    • pp.443-449
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    • 2013
  • The purpose of this study is to propose an enhanced variable-speed control method of ground-water circulation pumps using inlet and outlet ground-water temperature difference and analyze its effect for the ground source multi-heat pump system installed in a single-family house. As a result, it has shown to significantly reduce the electricity use of ground-water circulation pump and improve overall system Coefficient of Performance (COP) due to the proposed variable-speed control under partial load conditions after oversized and inefficient single-speed pump retrofit.

Experimental Study on the Lateral Pressure Resistance of Free-form Concrete Panel (FCP) Side Form (FCP(Free-form Concrete Panel) 측면 거푸집의 측압 저항능력 실험)

  • Youn, Jong-Young;Yun, Ji-Yeong;Lee, Chang-Woo;Lee, Donghoon
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2021.05a
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    • pp.8-9
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    • 2021
  • FCP requires different curvatures and shapes according to the method of division, and it is necessary to manufacture a formwork accordingly. FCP production equipment consists of CNC equipment and side shape control equipment. This can be implemented in various shapes of upper, lower, and side surfaces. In the side shape control equipment, it is implemented as a variable side formwork. Among the required performance of the variable side formwork, there is stiffness against side pressure, which needs to be verified. Therefore, in this study, the FCP fabrication experiment is conducted with the developed variable side formwork. By analyzing the error in the shape of the fabricated FCP, the lateral pressure resistance capability of the side form is measured and verified.

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The Problems Which Appeared in 13 Year Old Pupils' Performing Experiment of Textbook: Pupils' Suggested Aims, Their Identifying Relevant Variables, and the Relations between the Suggested Aims and the Drawn Conclusions (중학생의 교과서 실험 수행에서 나타난 문제점:실험 목표와 관련 변인 인식 및 인식한 목표와 도출된 결론의 관련성)

  • Kim, Jae-Woo;Oh, Won-Kun
    • Journal of The Korean Association For Science Education
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    • v.18 no.1
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    • pp.35-42
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    • 1998
  • To investigate 13 year old pupils' suggested aims, recognition of relevant variable, and the relationship between the suggested aim and the conclusion which is drawn by pupils, we classified experiments in textdbook into three cases: (1) Case involving dependent variable and independent variable in the title of experiment, (2) Case involving dependent variable only, where pupils can know independent variable from the content of textbook, (3) Case involving dependent variable only, where pupils hardly can know independent variable from the content of textbook. In respect of the aims which pupils suggested, the suggested aims were reduced to the title of experiment in case(1). However, the suggested aims were divided into several forms which is not relevant to the content of experiment in case (2), (3). This shows that pupils are affected by the title of experiment according to how the variable is involved in the title of experiment. This is supported by the fact that when the variable is described in the title, the suggested aim is reduced to the title of experiment. On the other hand, there was a relationship between the suggested aim and the drawn conclusion in case (1). But there was few relationships in case (2) and (3). Surprisingly, the drawn conclusion in case(1) was not consistent with the expected one because of the inappropriate experimental setting. We need to be more careful in experimental setting, pupils' cognitive ability, and openness of experiment to help pupils perform experiment successfully.

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Effects of loading history on seismic performance of SRC T-shaped column, Part I: Loading along web

  • Wang, J.;Liu, Z.Q.;Xue, J.Y.;Hu, C.M.
    • Structural Engineering and Mechanics
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    • v.68 no.2
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    • pp.193-201
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    • 2018
  • This paper describes an experimental study on the seismic performance of steel reinforced concrete (SRC) T-shaped columns. The lateral loads were applied along the web of the column with different loading histories, such as monotonic loading, mixed loading of variable amplitude cyclic loading and monotonic loading, constant amplitude cyclic loading and variable amplitude cyclic loading. The failure modes, load-displacement curves, characteristic loads and displacements, ductility, strength and stiffness degradations and energy dissipation capacity of the column were analyzed. The effects of loading history on the seismic performance were focused on. The test results show that the specimens behaved differently in the aspects of the failure mode subject to different loading history, although all the failure modes can be summarized as flexural failure. The hysteretic loops of specimens are plump, and minimum values of the failure drift angles and ductility coefficients are 1/24 and 4.64, respectively, which reflect good seismic performance of SRC T-shaped column. With the increasing numbers of loading cycles, the column reveals lower bearing capacity and ductility. The strength and stiffness of the column with variable amplitude cyclic loading degrades more rapidly than that with constant amplitude cyclic loading, and the total cumulative dissipated energy of the former is less.