• Clinical and Experimental Pediatrics
• /
• 제53권7호
• /
• pp.759-765
• /
• 2010

Purpose: This study evaluated the clinical manifestations of and risk factors for pituitary insufficiency in children and adolescents with Rathke's cleft cysts. Methods: Forty-four patients with Rathke's cleft cysts younger than 19 years who visited Seoul National University Children's Hospital between January 1995 and September 2009 were enrolled. Rathke's cleft cysts were confirmed histologically through an operation in 15 patients and by brain magnetic resonance imaging (MRI) in 29 patients. The clinical, hormonal, and imaging features were reviewed retrospectively. Results: The clinical presentation of symptomatic patients was as follows: headache (65%), endocrinopathy (61%), and visual disturbance (19%). Endocrinopathy included central precocious puberty (18%), diabetes insipidus (14%), general weakness (11%), and decreased growth velocity (7%). After surgery, hyperprolactinemia resolved in all patients, but growth hormone insufficiency, hypothyroidism, and diabetes insipidus did not improve. Pituitary insufficiency except gonadotropin abnormality correlated significantly with severe headache, visual disturbance, general weakness, and cystic size. Suprasellar extension of cysts and high signals in the T2-weighted image on brain MRI were related to hypothyroidism, hypocortisolism, and diabetes insipidus. Multivariable linear regression analysis showed that only general weakness was a risk factor for pituitary insufficiency ($R^2$=0.549). Conclusion: General weakness is a risk factor for pituitary insufficiency in patients with Rathke's cleft cysts. When a patient with a Rathke's cleft cyst complains of general weakness, the clinician should evaluate pituitary function and consider surgical treatment.

• 융합신호처리학회논문지
• /
• 제16권2호
• /
• pp.35-39
• /
• 2015

Auditory and visual stimuli presented in the peripheral visual field were perceived as spatially coincident when the auditory stimulus was presented five to seven degrees outwards from the direction of the visual stimulus. Furthermore, judgments of the perceived distance between auditory and visual stimuli presented in the periphery did not increase when an auditory stimulus was presented in the peripheral side of the visual stimulus. As to the origin of this phenomenon, there would seem to be two possibilities. One is that the participants could not perceptually distinguish the distance on the peripheral side because of the limitation of accuracy perception. The other is that the participants could distinguish the distances, but could not evaluate them because of the insufficient experimental setup of auditory stimuli. In order to confirm which of these two alternative explanations is valid, we conducted an experiment similar to that of our previous study using a sufficient number of loudspeakers for the presentation of auditory stimuli. Results revealed that judgments of perceived distance increased on the peripheral side. This indicates that we can perceive discrimination between audio and visual stimuli on the peripheral side.

• 한국인터넷방송통신학회논문지
• /
• 제9권1호
• /
• pp.53-59
• /
• 2009

다시점 비디오는 데이터 양이 매우 많아서 이를 효과적으로 저장하고 전송하기 위해서는 새로운 압축 부호화의 기술 개발이 필수적이다. 계층적 깊이 영상은 다시점 비디오를 효과적으로 부호화할 수 있는 방법으로 여러 시점의 컬러와 깊이 영상을 합성하여 하나의 데이터 구조로 만든 것이다. 본 논문에서는 실제 거리비교, 오버랩 문제해결, 보간법을 이용한 효율적인 계층적 깊이 영상 표현을 통해서 다시점 영상에 대한 압축 효율을 향상시키는 방법을 제안 하였다. 실험 결과를 통해서 압축 성능 향상을 얻을 수 있었다.

• 유통과학연구
• /
• 제16권12호
• /
• pp.13-21
• /
• 2018

Purpose - Because it is not possible to assess the quality of service products before experiencing them, one feature of a service product is quality uncertainty; hence consumers may react sensitively to pricing. It is necessary to investigate how different pricing strategies affect consumer purchase intention depending on the level of service quality uncertainty. Research design, data, and methodology - The authors have investigated the potential impact of the level of service quality uncertainty, price discount rate and presentation method on consumer purchase intention. A play was selected as an experimental stimulus, and Vietnamese consumers were surveyed to verify the hypotheses. Results - When uncertainty regarding service quality is low, consumer purchase intention is higher when the price discount rate is high or when the price is low. When uncertainty regarding service quality is high, if the normal price, discount rate, and discounted price are presented simultaneously, consumer purchase intention is higher when the price discount rate is low, but when only the discounted price is presented, purchase intention is higher when the price discount rate is high. Conclusions - The results of this study can provide valuable practical implications for pricing for service products with quality uncertainty.

• Clinical and Experimental Pediatrics
• /
• 제53권5호
• /
• pp.657-660
• /
• 2010

Tuberculosis is primarily a pulmonary disease, but extra-pulmonary manifestations are not uncommon, especially in children and adolescents. Ten percent of extra pulmonary tuberculosis localizes to the bones and joints, and 56% of such cases affect the spine. We treated a childhood case of spinal tuberculosis misdiagnosed as muscular dystrophy in a patient without specific constitutional symptoms. We report this case because the patient had an unusual presentation of spinal tuberculosis.

• Clinical and Experimental Pediatrics
• /
• 제53권11호
• /
• pp.931-935
• /
• 2010

Juvenile idiopathic arthritis (JIA) is comprised of a heterogeneous group of several disease subtypes that are characterized by the onset of arthritis before the age of 16 years and has symptoms lasting at least 6 weeks. The previous classification of JIA included seven different categories, whereas its current classification was compiled by the International League of the Association for Rheumatology, and replaced the previous terms of "juvenile chronic arthritis" and "juvenile rheumatoid arthritis," which were used in Europe or North America, respectively, with the single nomenclature of JIA. As mentioned above, JIA is defined as arthritis of unknown etiology that manifests itself before the age of 16 years and persists for at least 6 weeks, while excluding other known conditions. The clinical symptoms of JIA can be quite variable. Several symptoms that are characteristic of arthritis are not necessarily diagnostic of JIA and may have multiple etiologies that can be differentiated with careful examination of patient history. The disease may develop over days or sometimes weeks, thereby making the diagnosis difficult at the time of presentation. To make a clinical diagnosis of JIA, the first step is to exclude arthritis with known etiologies. Of note, late treatment due to excessive delay of diagnosis can cause severe damage to joints and other organs and impair skeletal maturation. Therefore, early detection of JIA is critical to ensure prompt treatment and to prevent long-term complications including the likelihood of disability in childhood.

• Journal of Electrical Engineering and Technology
• /
• 제2권4호
• /
• pp.478-484
• /
• 2007

This paper deals with the high efficient vector control for the reduction of copper losses of the doubly fed motor. Firstly, the feedback linearization control based on Lyapunov approach is employed to design the underlying controller achieving the double fluxes orientation. The fluxes# controllers are designed independently of the speed. The speed controller is designed using the Lyapunov method especially employed to the unknown load torques. The global asymptotic stability of the overall system is theoretically proven. Secondly, a new Torque Copper Losses Factor is proposed to deal with the problem of the machine copper losses. Its main function is to optimize the torque in keeping the machine saturation at an acceptable level. This leads to a reduction in machine currents and therefore their accompanied copper losses guaranteeing improved machine efficiency. The simulation and experimental results in comparative presentation confirm largely the effectiveness of the proposed DFIM control with a very interesting energy saving contribution.

• 대한지구과학교육학회지
• /
• 제4권1호
• /
• pp.74-82
• /
• 2011

The purpose of this study is to examine the effect of the science gifted children's creativity and scientific attitude development by e-PBL based scientific writing program. This program is composed of 4 instructions (13 hours), and its learning contents are made up to guide reading the related science books and understanding the contents through mind map to find out a solution by themselves, also, making an independent problem into group issue and setting up the plan for solution through small group cooperative learning, finally, performing activities like writing, presentation, evaluation and discussion according to the plan for solution. To examine the effect of creativity and scientific attitude by the program, 40 students of elementary science gifted children group in the Busan national university of education were selected for an experimental group. The review result is that, Firstly, the program affected positively creativity improvement of elementary science gifted children, Secondly, the program affects positively scientific attitude improvement of them as well. In conclusion, the program affects positively their creativity and scientific attitude.

• Clinical and Experimental Pediatrics
• /
• 제45권6호
• /
• pp.804-808
• /
• 2002

저자들은 폐형성부전과 다발성 선천성 기형을 가지고 있는 생존 출생아에서 말초혈액의 염색체 검사 및 FISH로 확인된 trisomy 22 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• Clinical and Experimental Pediatrics
• /
• 제54권2호
• /
• pp.86-89
• /
• 2011

Traumatic ventricular septal defect (VSD) resulting from blunt chest injury is a very rare event. The mechanisms of traumatic VSD have been of little concern to dateuntil now, but two dominant theories have been described. In one, the rupture occurs due to acute compression of the heart; in the other, it is due to myocardial infarction of the septum. The clinical symptoms and timing of presentation are variable, so appropriate diagnosis can be difficult or delayed. Closure of traumatic VSD has been based on a combination of heart failure symptoms, hemodynamics, and defect size. Here, we present a case of a 4-year-old boy who presented with a traumatic VSD following a car accident. He showed normal cardiac structure at the time of injury, but after 8 days, his repeated echocardiography revealed a VSD. He was successfully treated by surgical closure of the VSD, and has been doing well up to the present. This report suggests that the clinician should pay great close attention to the patients injured by blunt chest trauma, keeping in mind the possibility of cardiac injury.