• Archives of Pharmacal Research
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• 제20권6호
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• pp.637-642
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• 1997

Degradation of a compound with a hydroxyl group during the course of its diffusion across the skin was investigated. Based on the experimental findings of ashortened retention time of a degradant peak from post-diffusion samples and from the ability to evaporate radioactivity from such samples, it seems that during diffusion the parent compound degrades into a more hydrophilic product which is then oxidized. A tritium label at the carbon with a hydroxyl group was released as a tritiated water. When the post-diffusion samples were left open to the air allowing evaporation of water, there was a corresponding decrease in radioactivity of such samples. There was a linear relationship between the time left open and the fraction of radioactivity lost. When such samples were fractionated by HPLC, and then had their radioactivities measured by scintillation counting, two peaks wre identified. The first peak, which may be attributable to tritiated water, was eluted at the same retention time as the solvent front. The second peak eluted at the retention time of the parent compound. When the evaporation/loss of radioactivity experiment was repeated using a $^{14}C$-labeled compound there was no significant loss of radioactivity, indicating that the earlier loss with $^{3}H$-labeled compound was related to the formation and loas sof tritiated water.

• 실천공학교육논문지
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• 제9권1호
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• pp.41-48
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• 2017

본 논문에서는 기초 디지털 논리 회로 실습 교육 과정을 설계하기 위해, 디지털 출력을 갖는 아두이노 프로그래밍을 통한 디지털 논리회로 제어 방법을 제안하였다. 디지털 논리회로와 아두이노 프로그래밍 실습은 국내 교육과정의 고등학교 및 대학교의 공학 계열 학과에서 필수 교육과정으로 지정하고 있다. 하지만 실제 실습에는 디지털 논리회로와 아두이노 프로그래밍이 결합된 예제가 부족하고, 디지털 논리회로를 설계하고 오실로스코프 보다 저가의 비용으로 실험할 수 있는 교육 과정이 부족하다. 이에 본 논문에서는 이 문제를 해결하는 디지털 출력 명령을 통한 아두이노 프로그래밍을 통해, 디지털 논리회로를 제어하고 실습해보는 한 학기 기간의 기초 디지털 논리 회로 실습 교육 과정을 제안하였다.

• Journal of Animal Science and Technology
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• 제56권5호
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• pp.20.1-20.5
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• 2014

An experiment was conducted to evaluate the effect of form and particle size of feed supplemented with L-threonine on growth performance, carcass characteristic and blood biochemical parameters of broiler chickens. The experimental design was a $2{\times}2{\times}2$ factorial arrangement of treatments evaluating two feed forms (pellet or mash), two feed particle sizes (fine or course), and two inclusion rates of dietary L-threonine (with or without) which adopted from 7 to 42 days of age. In this experiment, 360 a day old chicks in two sexes were assigned in each treatment and each experimental unit was included 15 chicks. Feed consumption and weight gain were measured weekly. At 35 days of age, blood samples were taken to analysis blood biochemical parameters. At the end of the experimental period, two birds were slaughtered in each treatment and carcass analysis was carried out. The results showed that the effect of feed form on body weight gain and feed intake in whole of experimental period was significant (P < 0.05). Broilers fed pelleted diets had more weight gain than the mash group. Growth performance parameters were not affected by feed particle size and dietary L-threonine supplementation in whole of experimental period (P > 0.05). The results of carcass analysis showed that liver and gizzard relative weights were influenced by feed form (P < 0.05). However, pancreas and liver relative weights were affected by feed particle size and dietary L-threonine supplementation, respectively (P < 0.05). Triglyceride and VLDL levels were affected by feed form and dietary L-threonine supplementation (P < 0.05). The effect of feed particle size on blood biochemical parameters was not significant (P > 0.05). In conclusion, the experimental results indicated that feed form increased feed consumption and weight gain in whole of experimental period (1 to 42 days of age) while feed particle size and dietary L-threonine had no effect on broiler performance.

• 과학교육연구지
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• 제41권1호
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• pp.80-97
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• 2017

본 연구의 목적은 초등학교 과학의 생물과 환경 단원에서 백워드 디자인의 적용 효과를 알아보는 데 있다. 백워드 디자인은 학습의 결과를 먼저 명료화한 후, 이것을 토대로 수업 방법과 교수 요목을 결정하는 것이다. 이 방법은 교육 내용-평가-학습 활동 사이의 일관성을 유지할 수 있고 학생들의 진정한 이해를 도울 수 있는 장점이 있다. 본 연구 대상은 초등학교 6학년 78명이며, 이 모델 적용에 따른 효과를 알아보기 위해 학생들이 수행한 프로젝트 자료, 과학 학습 정서 검사, 학업 성취도 검사 자료가 수집되었다. 수집된 자료는 SPSS 23 통계 패키지로 t-test와 ANCOVA 검증이 이루어졌다. 연구의 결론은 다음과 같다. 첫째, 백워드 디자인을 적용한 실험 집단에서 학생들이 2가지 프로젝트를 수행한 결과물을 분석한 결과 과학의 내용에 대해서는 비교적 정확하게 이해하고 있었으나 창의적인 산출물을 만들어내지는 못함을 알 수 있었다. 둘째, 백워드 디자인에 따라 수업을 하여도 과학 학습정서 부문의 성취가 유의미하게 향상되지는 않음을 알 수 있었다. 셋째, 백워드 디자인에 의해 학생들의 학업 성취도는 유의미한 향상을 보였다.

• 한국간호교육학회지
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• 제14권2호
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• pp.273-281
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• 2008

Purpose: This study was performed to investigate the effects of aromatherapy on headache, stress and immune response of students with tension-type headache. Method: This study employed a two-group pre-post test study design. Data was collected from 44 subjects. Twenty-two subjects were assigned to the experimental group and received aromatherapy massage every other day for 3 weeks, but the other 22 subjects were in the control group and did not receive any intervention. Experiment had been conducted from Apr. 9 through Aug. 25, 2001 and intensity of headache, stress response (serum cortisol, life stress) and immune response(T-cell and natural killer cell ratio) were measured in the course of aromatherapy for both experimental group and control group. Data were analyzed by using $X^2$-test, t-test, Paired t-test and repeated measures ANOVA. Result: Headache scores, serum cortisol levels and life stress scores were significantly decreased in the experimental group after treatment compared to the control group. Conclusion: These findings is suggested that the aromatherapy could be an effective nursing intervention in relaxing and relieving the pain caused by tension-type headache for students.

• 대한치과보철학회지
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• 제9권1호
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• pp.29-34
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• 1969

Occlusal force is a critical factor affecting the condition and structure of the periodontium. When the occlusal forces exceed the physiologic adaptive capacity of the tissues, tissue damage ensues. Such damage is referred to as trauma from occlusion. Excessive pressure causes compression, degeneration and realignment of the periodontal ligament fibers so that they are paralleled perpendicular to the tooth and bone. By inducing excessive occlusal forces with a high amalgam filling on rat's molar, the author observed histologic alterations of the periodontal ligament fibers by means of Hematoxylin-eosin, Van Gieson and Aldenyde fuchsin stainings. The results of the study were observed as follows: 1) The excessive occlusal forces altered arrangement of the collagenous fibers. 2) The arrangement of the oblique fibers showed appreciable differences between the control group and the group subjected to 10 days experimental trauma from occlusion. 3) The realignment of the transseptal fibers was not found. 4) The arrangement of the oblique fibers after 15 days of trauma from occusion was similar to that of 10 days experimental group. 5) The oxytalan fibers were more abundant at the cementum rather than at the alveolar bone. 6) The excessive occlusal forces produced funnel-shaped widening of the oxytalan fibers, which followed wavy course. 7) The oxytalan fibers appeared to be distributed mainly around the middle third of the root rather than that of the apical third of the root during the experimental trauma from occlusion.

• 대한간호학회지
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• 제36권3호
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• pp.484-492
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• 2006

Purpose: The purpose of this study was to investigate the effects of a rehabilitation nursing program(RNP) for persons with disabilities. Method: a quasi-experimental pretest and post test study was used to examine the changes of patient's muscle strength, flexibility, self efficacy and health related quality of life at the completion of an 8-week education and physical exercise with a Thera-Band and Exercise Ball course. The subjects consisted of 40 adults who were disabled. Twenty-two experimental and 18 control subjects completed pre and post-test measures. Outcome variables were flexibility, hand grip, elbow flexor and extensor, knee flexor and extensor, self efficacy and quality of life. Independent t-test and ANCOVA were used to examine group differences by using SPSS 12.0 Result: Mean comparisons of the change scores revealed that the experimental group increased significantly in knee extremity flexor(p=0.035), extensor(p=0.039), flexibility(p=0.008), self efficacy(p=0.000), and quality of life(p=0.000). No significant group differences were found in each patient's hand grip, elbow flexor and extensor. Conclusion: RNP can improve lower extremity flexibility, muscle strength, self efficacy and health related quality of life in people with disabilities. The intervention to tailor exercise and education to the unique needs of the disability was suggested for further study.

• Preventive Nutrition and Food Science
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• 제20권1호
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• pp.60-66
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• 2015

The aim of this study was to determine the heat-penetration characteristics using stationary and rotary retorts to manufacture Kimchi soup. Both heat-penetration tests and computer simulation based on mathematical modeling were performed. The sterility was measured at five different positions in the pouch. The results revealed only a small deviation of $F_0$ among the different positions, and the rate of heat transfer was increased by rotation of the retort. The thermal processing of retort-pouched Kimchi soup was analyzed mathematically using a finite-element model, and optimum models for predicting the time course of the temperature and $F_0$ were developed. The mathematical models could accurately predict the actual heat penetration of retort-pouched Kimchi soup. The average deviation of the temperature between the experimental and mathematical predicted model was 2.46% ($R^2=0.975$). The changes in nodal temperature and $F_0$ caused by microbial inactivation in the finite-element model predicted using the NISA program were very similar to that of the experimental data of for the retorted Kimchi soup during sterilization with rotary retorts. The correlation coefficient between the simulation using the NISA program and the experimental data was very high, at 99%.

• 한국간호교육학회지
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• 제16권1호
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• pp.121-128
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• 2010

Purpose: Bystander CPR has demonstrated improved survival of out-of-hospital cardiac arrest. The purpose of this study was to evaluate the effects of CPR education in the rural community. Method: One hundred eighty-nine rural laypersons (105 in the experimental group and 84 in the control group) participated in this study. In the experimental group, questionnaires were completed after participating in a small group BLS (Basic Life Support) course. In the control group questionnaires were collected from two rural health service centers. Data were analysed using $X^2$test, independent t-test and paired t-test. Result: There were significant differences in barriers to performing CPR, attitude and intention toward CPR and necessity recognition between the two groups. Conclusion: The proportion of positive attitudes toward CPR and willingness to perform CPR was higher in the experimental group than the control group. CPR education increased anxiety of being sued because of a bad outcome. For future CPR education for laypersons, the reluctance of bystanders to perform CPR should be reconsidered and CPR education should be extended to the rural community.

• 대한수학교육학회지:학교수학
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• 제2권2호
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• pp.475-487
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• 2000

As a result of carrying out t-test against the learning activity that used the learning materials designed by level, significant disparity was found. Thus, it was found that hte effect of this learning activity became more visible with lapse of time. But the major cause by which there appeared small significant disparity as a result of testing is that the units of experiment were limited and that the period of using the learning materials was not long. In an analysis on the results of interest test, the experimental class also appeared to show the average score that was higher than that of the comparative class by 0.10 after converting a decimal point. The outcome of attitude test was that the experimental class showed a higher average score by 0.11, as a result of converting a decimal point, than that of the comparative class. So, a large number of students showed an improved reaction. But, there seemed some problems of the learning materials or the method of progressing the activity in changing under achievement students or students who avoided studying math. When the effect of the level-based learning activity was investigated, more than 80% of the experimental class’s students showed a positive reaction. Thus, it could be judged that students, who felt some burden at studying math, might be served more largely, not by teacher’s uniform instruction, but by an individual learning using the level-based learning materials that enabled them to do a systematic self-learning for themselves.