• Clinical and Experimental Reproductive Medicine
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• v.32 no.4
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• pp.337-346
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• 2005

Objective: The oligosaccharide moieties of glycoproteins and proteoglycans have a vital function in blastocyst differentiation. Concanavalin (ConA), a lectin, is known to bind on the preimplantation embryos, especially on blastocyst. In this study, we investigated whether ConA can modulate the trophoblast development and about the regulating mediator. Also, we investigated whether expansion is enough for hatching procession of the mouse blastocyst. Method: Embryos were collected at 72 h post hCG injection and chemicals were treated after 24 h (96 hr post hCG injection). ConA or calcium ionophore A23187 were exposed to blastocyst and than analysis the developmental process for 48 hr. Intracellular free-$Ca^{2+}$ concentration in trophectoderm was measured with confocal laser microscope after exposing to ConA or calcium ionophore A23187. ConA-pretreated blastocyst exposed to the calcium ionophore A23187 and then analyzed the developmental process. Otherwise ouabain was treated to the blastocyst to block the $Na^+/K^+$-ATPase activity. Results: In contrast to the control blastocyst, the ConA-exposed blastocysts developed beyond the expansion stage with significantly high rate (90.4%) at 12 h post administration. ConA induced an increase the intracellular $Ca^{2+}$ concentration in trophectoderm. Calcium ionophore A23187 also stimulated expansion of blastocyst. Most of the control blastocysts developed to the hatching stage at 144 h post hCG injection. However, strongly 65% of the ConA-exposed embryos were arrested at expanded stage at same time point. The developmental progression rates to hatching stage of both ConA- and calcium ionophore A23187-expose blastocysts were significantly lower than that of the control. However ConA-pretreated embryos developed to the hatching stage like control embryos. Ouabain showed a tendency to delayed the progress to expansion stage but did not inhibit the development to the hatching stage. Conclusion: ConA-mediated expansion is the result of the increase of intracellular free-calcium in blastocyst stage embryo. It is suspected that expansion of the blasocyst is a essential indirect factor in hatching and the calcium may triggering the cellular mechanisms for the both expansion and hatching progression.

• Journal of Welding and Joining
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• v.29 no.1
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• pp.115-122
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• 2011

This study is to propose an in-process monitoring system for micro resistance spot welding processes using minute accelerometer. A minute accelerometer is mounted on the upper moving electrode tip holder. With its high sensitivity and frequency response characteristics, accelerometer output signal has been successfully recorded and integrated twice to reflect electrode expansion during micro spot welding processes. The analysis of electrode expansion pattern was attempted to find its correlation with spot weld quality. Major previous findings1-6) regarding spot weld quality assessment with the electrode expansion signal in large scale resistance spot welding processes were proved to be true in this in-process monitoring system.

• Journal of Advanced Marine Engineering and Technology
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• v.38 no.7
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• pp.828-833
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• 2014

In this paper, the performance characteristics for newly developed ejector refrigeration system, which is that the part of saturated vapor from liquid-vapor separator after ejector expansion process is entrained in ejector, and the saturated liquid flows in the evaporator and compressed with the rest of vapor in separator, is studied. The reasons of the performance improvement of refrigeration system are that the refrigeration capacity is increased due to quality reduction after iso-entropic expansion process by ejector and the compression work is reduced because of the relatively high pressure of vapor refrigerant before compression process. The comparison results of the ejector system entraining expansion gases with the present residential freezer show that the COP increases to 27.8% maximum in case of the pressure drop to 65% of high pressure of freezer, and to 40.1% for 75% pressure drop of refrigerant R401A. The COP improvement rate with 20%~60% pressure lift in diffuser of ejector is only 2.6%~3%.

• Health Policy and Management
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• v.24 no.3
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• pp.205-218
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• 2014

Background: Most studies on the national health insurance benefit expansion policy have focused on policy tools or decision-making process. Hence there was not enough understanding on how policies are actually implemented within the specific policy context in Korea which has a national mandatory health insurance system with a dominant proportion of private providers. The main objectives of this study is to understand the implementation process of the benefit coverage expansion policy. Unlike other implementation studies, we tried to examine both the process of implementation and decision making and how they interact with each other. Methods: Interviews were conducted with the ex-members of the Health Insurance Policy Review Committee. Medical doctors who implement the policy at the 'street-level' were also interviewed. To figure out major variables and the degree of their influences, the data were analyzed with Winter's Policy Implementation Model which integrates the decision making and implementation phases. Results: As predicted by the Winter model, problems in the decision making phase, such as conflicts among the members of committee, lack of applicable causal theories application of highly symbolic activities, and limited attention of citizen to the issue are key variables that cause the 'implementation failure.' In the implementation phase, hospitals' own financial interests and practitioners' dependence on the hospitals' guidance were barriers to meeting the policy goals of providing a better coverage for patients. Patients, the target group, tend to prefer physicians who prescribe more treatment and medicine. To note, 'fixers' who can link and fill the gap between the decision-makers and implementers were not present. Conclusion: For achieving the policy goal of providing a better and more coverage to patients, the critical roles of medical providers as street-level implementers should be noted. Also decision making process of benefit package expansion policy should incorporate its influence on the implementation phase.

• Transactions of Materials Processing
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• v.18 no.7
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• pp.565-571
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• 2009

This paper is concerned with the analysis on the surface stress profiles of perfectly plastic material in backward extrusion process. Due to heavy surface expansion appeared usually in the backward extrusion process, the tribological conditions along the interface between the material and the punch land are very severe. In the present study, the analyses have focused to reveal the surface conditions at the contact boundary for various punch shapes in terms of surface expansion, contact pressure, and relative movement between punch and workpiece which consists of sliding velocity and distance, respectively. Punch geometries adopted in the analysis include concave, hemispherical, pointed and ICFG recommended shapes. Extensive simulation has been conducted by applying the rigid-plastic finite element method to the backward extrusion process under different punch geometries. The simulation results are summarized in terms of surface expansion, contact pressure, sliding velocity and sliding distance at different reduction in height, deformation patterns, and load-stroke relationship, respectively.

• Proceedings of the Korea Association of Information Systems Conference
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• 2001.12a
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• pp.438-450
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• 2001

This study is to classify the typology of e-business model based on the practical strategic model for successful e-business implementation. For that purpose, we review the conceptual framework of e-business and collected the data from 127 companies implementing e-business. The study is conducted in three phases as follows. First, six factors consisted of 22 items are derived through factor analysis. Second, Cluster analysis is employed to group the firms into different strategic patterns. A five-cluster solution is found to maximize the distances between cluster means across the six factor patterns. The models are named as 'ascendancy and convergence', 'expansion and moderate price', 'expansion and improvement of quality', 'ascendancy and process', and 'improvement of quality' respectively. Third, ANOVA is used to examine the impact on the performance differences attributable to the models. The results of the study are; (1) the 'ascendancy and process', 'expansion and improvement of quality' and 'expansion and moderate price' models were associated with significantly higher performance levels than the 'improvement of quality' model, and (2) the hybrid strategies are needed to implement e-business successfully based on the 'ascendancy and process' model.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2020.06a
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• pp.151-152
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• 2020

Recently, concrete expansion anchors which are a type of post-installed mechanical anchors are widely used in reinforcement concrete structures. In order to be used in the reinforced concrete structures designed in accordance with ACI 318-19 or ACI 349-13, the structural performance tests of the concrete expansion anchors should be conducted in accordance with ACI 355.2. The effectiveness factor(k) of concrete expansion anchors should be determined through the reference tests and used for the design of anchorage to concrete according to ACI 318-19 or ACI 349-13. In this study, we will look into the method for determining the effectiveness factor(k) of concrete expansion anchors and anchorage design process of concrete expansion anchors by using the effectiveness factor(k) in accordance with ACI 349-19.

• Transactions of Materials Processing
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• v.19 no.6
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• pp.337-343
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• 2010

Current need of weight reduction in automotive part increases the application for high strength steel (HSS). The various types of high strength steels have been used to produce chassis part, control arms and trailing arms for weight reduction and increasing of fatigue durability such as dual phase steel (DP) and ferrite bainite steel (FB). But, DP and FB steels have proven to show inferiority in durability as well as press formability. Edge cracking occurred often in flange forming and hole expansion processes is the major failure encountered. This paper discussed the behavior of edge stretchability of high strength steel of DP and FB steels. Experimental works have been conducted to study the effect of punch clearance and burr direction on hole expansion ratio (HER). Also finite element simulation (FEM) has been preformed to clarify the mechanism of flange crack and support the experimental results on HER of DP and FB steels. It was simulated the whole process of blanking process following by hole expansion process and ductile fracture criterion named the modified Cockcroft-Latham model which was used to capture the fracture initiation. From the hole expansion tests and FEM simulation studies it was concluded that ferrite bainite steel showed better stretch-flangeability than dual phase steel. It was attributed to the lower work hardening rate of ferrite bainite steel than dual phase steel at the sheared edge.

• Health Policy and Management
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• v.25 no.2
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• pp.129-139
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• 2015

Background: Policy network theory was proved to be an appropriate analytic tool for the current social welfare policy making process. This study aimed to analyze policy making process related to the nurse expansion and policy output while focusing on the interactions and activities among various policy actors. Methods: In this study, we used reports related to the need for expansion of nursing personnel journals, dissertations, newspaper articles, for hearings and debate policies for securing nurse data, and interviews. We examined three components of policy network, that is, policy actors, interactions, linkage of interest. Results: For that to expand the nurse before the 2000s in expanding the supply of medical supplies have been conducted without much disagreement among policy actors under the government's initiative. However, there was lacked a close relationship between the expanding supply of nurses and inaccurate analysis of supply and demand. As the policy is applied between the various policy actors' needs and claims, conflict was intensified and many policy options had been developed. Government only took a role as a coordinator among policy actors in the 2000's. Also, it was difficult to find sufficient and clear evidence that policy-making process based on fair judgment. Conclusion: Therefore, it is urgently required to determine the policy through a social consensus to address the appropriate policy means and the process by correct analysis of the policy issues.

• Ceramist
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• v.22 no.4
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• pp.429-451
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• 2019

Quartz glass is a key material for making semiconductor process components because of its purity, low thermal expansion, high UV transmittance and relatively low cost. Domestic quartz glass has a market worth about 500 billion won in 2018, and the market power of Japanese materials is very high. Quartz glass for semiconductor process can be divided into general process and exposure. For general process, molten quartz glass is mainly used, but synthetic quartz glass with higher purity is preferred. Synthetic quartz glass is used as the photomask for the exposure process. Recently, as semiconductors started the sub-nm process, the transition from the transmission type using ArF ultraviolet (194 nm) to the reflection type using EUV ultraviolet (13.5 nm) began. Therefore, the characteristics required for the synthetic quartz glass substrates used so far are also rapidly changing. This article summarizes the current technical trends of quartz glass and recent technical issues. Lastly, the present situation and development possibility of quartz glass technology in Korea were diagnosed.