• Journal of Genetic Medicine
• /
• 제14권1호
• /
• pp.8-17
• /
• 2017

Purpose: Pulse wave velocity (PWV) is an indicator of arterial stiffness, and is considered a marker of vascular damage. However, a genome-wide association study analyzing single nucleotide polymorphisms (SNPs) associated with brachial-ankle PWV (baPWV) has not been conducted in healthy populations. We performed this study to identify SNPs associated with baPWV in healthy populations in Korea. Materials and Methods: Genomic SNPs data for 2,407 individuals from three sites were analyzed as part of the Korean Genomic Epidemiologic Study. Without replication samples, we performed multivariable analysis as a post hoc analysis to verify the findings in site adjusted analysis. Healthy subjects aged between 40 and 70 years without self-reported history or diagnosis of hypertension, diabetes, hyperlipidemia, heart disease, cerebrovascular disease and cancer were included. We excluded subjects with a creatinine level >1.4 mg/dL (men) and 1.2 mg/dL (women). Results: In the site-adjusted association analysis, significant associations (P<$5{\times}10^{-8}$) with baPWV were detected for only 5 SNPs with low minor allele frequency. In multivariable analysis adjusted by age, sex, height, body mass index, mean arterial pressure, site, smoking, alcohol, and exercise, 11 SNPs were found to be associated (P<$5{\times}10^{-8}$) with baPWV. The 5 SNPs (P<$5{\times}10^{-8}$) linked to three genes (OPCML, PRR35 and RAB40C) were common between site-adjusted analysis and multivariable analysis. However, meta-analysis of the result from three sites for the 11 SNPs showed no significant associations. Conclusion: Using the recent standard for genome-wide association study, we did not find any evidence of significant association signals with baPWV.

• 한국산학기술학회논문지
• /
• 제18권4호
• /
• pp.267-274
• /
• 2017

본 연구는 장기 요양이 환자의 체질량지수(Body Mass Index, BMI )와 지질대사(Lipid metabolism)에 미치는 영향을 확인하기 위한 비실험적, 후향적 조사연구이다. 연구 대상자는 경기도내 2개 요양병원에 3개월 이상 입원한 만 40- 65세 미만의 환자 120명을 대상으로 하였다. 연구 방법은 입원시와 입원 3개월 경과 후의 BMI와 총콜레스테롤 (Total cholesterol), 중성지방 (Tryglycerides, TG), 고밀도지단백 콜레스테롤 (High Density Lipoprotein, HDL) 저밀도지단백 콜레스테롤 (Low Density Lipoprotein, LDL) 수치를 비교 분석하고, 시간 경과에 따른 변화를 추적관찰하였다. 대상자의 일반적 특성은 기술통계, 빈도분석을 하였다. 또한 일반적 특성이 BMI 미치는 영향은 로지스틱 회귀분석을 실시하였다. 입원시과 입원 3개월 후의 BMI와 혈중지질농도의 변화는 paired t-test를 이용하여 분석하였다. 연구 결과, 혈중지질농도의 변화가 입원 3개월 후에 중성지방 (Triglycerides)이 유의하게 증가하였다(p<.05). 이는 급성기 치료 후 요양 및 재활을 위하여 장기 입원하는 환자는 잠재적으로 이상지질 혈증의 위험성이 높다는 것을 고려하고 이상지질혈증 예방 및 개선을 위한 운동, 식이교육을 포함한 건강교육이 필요하다는 것을 의미한다.

• Nutritional Sciences
• /
• 제5권1호
• /
• pp.34-39
• /
• 2002

The objective of tole study was to compare nutritional knowledge, attitudes and food practices of competitive athletes, recreational athletes and non-participants. All students enrolled at the University of Nebraska in an Introductory Nutrition course in which sports nutrition was stressed, were asked to participate in the study. The course was typical of many introductory nutrition courses ; about two thirds of the students were from the Department of Health, Physical Education and Recreation, and most of the students were encouraged to take this course by their advisers. The students were divided into three groups : 20 competitive athletes (mostly runners, swimmers, basketball players and football players for the University), 14 recreational athletes (who were involved in a planned exercise program at least 2 hours per week), and 19 non-participants. At the beginning of the semester, students completed a food frequency questionnaire, and a 24-hour food record based on the Food Guide Pyramid. A nutrition knowledge and attitude questionnaire was formulated specifically for this study, covering normal nutrition and sports nutrition. The results showed that consumption of foods from all Food Guide Pyramid food groups except the fats/oils/sweets group was not significantly different among the three student groups. Regarding the fats/oils/sweets group, competitive athletes consumed significantly more numbers of servings than recreational athletes, while the recreational athletes consumed significantly more than non-participants (p<0.01). The total mean scores from the nutrition attitude and knowledge questionnaire were not significantly different among the three student groups. However, combined athletes (competitive athletes and recreational athletes) obtained significantly higher scores on some of the nutrition attitude questions (p<0.05). The results of the study indicate that athletes, significantly lower scores on some of the nutrition knowledge questions (p<0.05). The results of the study indicate that athletes, whether competitive or some of the nutrition knowledge questions (p<0.05). The results of the study indicate that athletes, whether competitive or recreational, had a very positive attitude regarding the effects of nutrition on their sports performance and health: however, these athletes did not appear to apply scientific principles of sports nutrition to their diet. In conclusion, advising athletes to simply increase or decrease their intakes of certain foods is too simplistic an approach for maintenance of good health and for better sporting performance. Athletes and non-athletes need continuous nutrition education to help with improving their competitive edge and food choices.

• Journal of Nutrition and Health
• /
• 제41권4호
• /
• pp.307-316
• /
• 2008

The purpose of the study was to investigate nutritional status of chronic obstructive pulmonary disease (COPD) patients and to find out the differences according to the stages of disease. From March to October, 2006, 41 stable male patients of mild to severe COPD patients were recruited from Seoul National University hospital. The patients' of body weight and fat free mass were assessed by bioelectrical impedance analysis. The nutritional status of the patients was also assessed by 3-day recall, index of nutritional quality (INQ), dietary diversity score (DDS), dietary variety score (DVS), food group index pattern and dietary quality index (DQI). The total of 41 patients were classified into three groups, stage I, stage II and stage III groups according to the classification of Global Initiative for Chronic Obstructive Lung Disease (GOLD) standard. The mean age of the patients in each stage were 67.2-66.9 years showing no significant difference. The ratio of $FEV_1$/FVC were $57.5{\pm}7.3$, $46.9{\pm}7.6$ and $38.2{\pm}6.8%$, respectively showing significant differences according to the stages of disease. The fat free mass of the stage II ($48.2{\pm}4.7kg$) and III ($47.3{\pm}4.5kg$) was significantly lower than that of stage I ($53.1{\pm}6.9kg$) patients. There were significant correlation of fat free mass with $FEV_{1}$, and BMI (body mass index) with $FEV_{1}$/FVC ratio (p < 0.05). COPD patients showed the diet-related clinical symptoms of anorexia, dyspnea, dyspepsia, and chewing difficulty. Daily intakes of calorie, K, vitamin $B_2$ and folate of the patients were very low ($83.8{\pm}20.7%$, $58.9{\pm}14.4%$, $70.7{\pm}19.6%$ and $74.4{\pm}10.2%$, respectively) however, they did not significantly different according to the stages of disease. Daily intake of calcium was significantly lower in the stage III patients (p < 0.05). The mean scores of dietary variety score was significantly lower in the stage III patients (p < 0.001). Dietary quality index of the patients were not different among the stages of disease and the scores indicated poor quality of diet. As a summary, we found that body fat free mass, regularity of exercise, frequency of having snacks and dietary variety score were significantly associated with the severity of chronic obstructive pulmonary disease.

• 여성건강간호학회지
• /
• 제4권3호
• /
• pp.309-321
• /
• 1998

The purpose of this study was to analyze the contents related to health in the three major monthly women's magazine that was printed from March, 1997 to February, 1998. The unit of analysis was the section of health, living life, and reaing child. The total number of related story of health was 317. The analysis was done according to the target, health management, topics and the informer by using frequency and number. The findings are as follows : 1. The contents were categorized by target people. The number of items for women was 113(35.6%), child(17.4%), family(15.5), husband(4.7%) and others(26.8%). Others were the contents that are impossible to classify. 2. The number of items of contents by health management was the related to health maintenance and promotion 120(47.8%), health care when they were deviated from health 26(10.3%), and those of both attributes 105(41.8%). 3. The number of items of contents by topics was the related to the occurrence, prevention and treatment of various kinds of disease 41(12..9%), diet 37(11.7%), academic information 11.3%, women's disease 10.4%, the effect of foods 6.0%, child's growth & development and child care 5.75, various kinds of therapy for health care 5.7%, sexual life 5.4% and exercise 4.7%. 4. The number of items of contents by informer was medical doctor 215(49%), lay person's case report or report of a struggle against a disease 12.3%, relevant organization of a related story(eg. family therapy research institute, physical therapist's or teacher's) 11.2%, and the contents of existing books or lecture 8.9%. Among those contents, only the one case from nurse or Korean nurses association as informer was founded, which is related to "skinship child care." In conclusion, this finding showed that women's magazine took a role as a important resource providing informations of health to women. it provides a challenge to the health professionals to have concerns on women's needs, and the content, source, and accuracy of the health related information and take part in the process producing information through such as screening and examining so as to give accurate information to women. Then women's magazine can take a role as a major resource for maintaining and promoting women's health. Finally, nurses's, who are professional health care providers, important and active role as informers toward the lay persons, especially for the women who are non-professional care givers at the family unit should be stressed. More active and continual monitoring and analyzing the contents related health in the mass media including magazine and Internet network in detail, and participating in establishing the system of adequate and precise information for women and lay persons from the nursing profession are required absolutely.

• 한방안이비인후피부과학회지
• /
• 제15권2호
• /
• pp.252-260
• /
• 2002

Introduction Urticaria is widely spread disease. About 15-20 $\%$ of population has experienced at least once in a life time. The etiology of urticaria is uncertain till now, and the affcting factors are various chemical material, physical factors, alcohol, fever, exercise, and hormone, etc. The symptoms of urticaria are small or large wheal-erythema reaction and itching or tingling sense. Cause there is no probe to detect the urticaria clearly, the treatment of urticaria is symptomatic. And mostly urticaria can be chronic and very hard to treat it fundamentally. Nowadays, many trials to treat the urticaria in oriental medical way show good curability. In this paper I'd like to report the treatment rate and degree of urticaria patients mostly using anti-histamine medication. Subjects From the outpatients who visited Korean Hospital of Kyunghee Kangnam during 2000-4 and 2002-1, the 36 chronic urticaria patients, at least more than 4 weeks from onset and 2weeks of treatment period, were chosen. Methods I evaluated the results of treatment with the following scale. Very Good: The all symptoms are clearly disappeared or one third of symptoms remain and sometimes eruption is appeared. Good: Half of the symptoms are improved but most of symptoms remain. No Change: No change appears before and after treatment. Worse: The degree and duration of eruption get worse than pre-treatment state. Results For Acupuncture treatment, I chose the several Acu points like Hapgok(합곡), Taichung(대충), Gokji(곡지), Yanggok(양곡), Yanggea(양계), and lmeup(족임읍), and usually lasted it 15 minutes. With the acupuncture treatment and herb medicine, 2-3 times a week, the patients whose treatment period was 2 to 4 weeks were 17(47.2$\%$), 4 to 8 weeks were 11(30.5$\%$), 8 to 12 weeks were 3(8.3$\%$), 12 to 16 weeks were 3(8.3$\%$), longer than 16 weeks were 2(5.5$\%$) Collecting the statistics of the frequency of prescripted herb medicine, Hyangsosan(향소산) was prescripted 21 times(58.3$\%$), Hyangsapyungwisan(향사평위산) was 15 times(41.6$\%$), Hwapisan(화피산) was 9 times(25$\%$), Yangwitang(양위탕) was 6 times(16.6$\%$), Bojungikkitang(보중익기탕가미) was 4 times(11.1$\%$), Yongdamsagantang (용담사간탕가미) was 4 times(11.1$\%$). The result of the treatments, evaluating with mentioned rate scale, was 11 cases(30.5$\%$) were Very Good degree, 19 cases(52.7$\%$) were Good , 6 cases(16.6$\%$) were No Change. No cases were Worse degree. Conclusion According to this research, we could say that chronic urticaria can be treated with Oriental medical methods. But more precise probes in both Oriental and Western medicine to diagnose the chronic urticaria should be established and we need to make standards for testing and diagnosing the chronic urticaria.

• 한국노년학
• /
• 제32권4호
• /
• pp.1137-1146
• /
• 2012

본 연구는 노인의 우울 유무에 따라 임파워먼트와 양생의 차이를 파악하는데 목적을 두고 있다. 연구방법은 S시와 Y시 소재 지역사회 복지관 프로그램 참여노인을 대상으로 설문지를 이용하여 실시하였다. 연구결과로 첫째, 대상자의 37.7%가 우울집단에 속하였고, 둘째, 우울의 유무에 따라 임파워먼트와 양생에서 차이가 나타났다. 셋째, 우울 유무에 따라 양생의 하위범주 중 도덕수양, 마음조양, 음식양생, 활동과 휴식, 운동양생, 수면양생에서 차이가 있었다. 넷째, 노인은 우울할수록 임파워먼트와 양생이 떨어졌으며, 임파워먼트가 높을수록 양생이 높았다. 따라서 노인의 임파워먼트 및 양생을 위한 프로그램 개발 시 노인의 우울이 고려되어야 함을 시사하고, 특히 양생은 신체적, 정서적 건강관리와 관련된 하위범주에서 차이가 나므로 우울한 노인일수록 신체적, 정서적 건강관리를 주의 깊게 확인해야 할 필요성이 있다. 마지막으로 양생은 노인의 임파워먼트와 관련이 있으므로 양생을 위해서 임파워먼트를 높여 주는 전략이 우선적으로 필요하다.

• 대한지역사회영양학회지
• /
• 제24권1호
• /
• pp.47-59
• /
• 2019

Objectives: Young athletes require adequate nutrition to maintain their athletic performance, growth and health. This study examined the status and needs of nutrition management and meal services for student athletes among the athlete's parents. Methods: The subjects were parents of elementary, middle, and high school athletes (n=323) from 18 schools participating mainly in the Sports Food Truck. The questionnaire included general characteristics, status and needs on nutrition management and meal service for student athletes, and satisfaction with the Food Truck. The survey was done during 2018. The data were analyzed according to the school groups using a ${\chi}^2-test$ or ANOVA. Results: Approximately 45% of subjects had difficulty in the nutrition management of athletes, and 87.1% had not received nutrition education. Approximately 74% wanted nutrition education held for athletes, and mainly wanted topics on nutrition management for health and eating for athletic performance. The preferred methods were lectures and cooking activity. The responses on the necessity of nutrition education for athletes, desired education topics, and desired times for education differed significantly according to the school groups (p<0.05). Most subjects also wanted nutrition information mainly through SNS. In the athlete's meal, breakfast and snacks were highlighted as the meal to supplement. Approximately 90.3% responded that providing a meal service is necessary. The subjects preferred snacks before/after exercise and dinner if a meal service was provided. They preferred Korean food, followed by snacks, and a dish meal. As the meal type, the subjects wanted the Food Truck and packed meal. The responses on necessity of a meal service (p<0.05), preferred food (p<0.001), and meal type (p<0.001) in the meal service differed significantly according to the school groups. Approximately 43% were satisfied with the Food Truck and 50.8% responded as average. They made suggestions for the Food Truck in terms of foods, operations and frequency. Conclusions: Based on the study results, nutrition education and meal service may support nutrition for student athletes considering the needs of the parents according to the school groups.

• 한국신경인지재활치료학회지
• /
• 제10권2호
• /
• pp.1-7
• /
• 2018

목적: 본 연구는 정상 발달아동과 자폐스펙트럼으로 진단받은 아동에게 목표관리 훈련을 실시하여 그 효과를 비교하였다. 방법: 연구대상자는 정상 발달아동 4명과 자폐스펙트럼으로 진단 받은 아동 4명을 대상으로 실시하였으며, 모든 대상자에게 동일한 목표관리 훈련을 제공하였다. 아동 및 보호자가 원하는 목표활동을 선정하여 3가지 활동에 모두 목표 관리훈련을 실시하였다. 중재기간은 총 10회로 주 2회씩 5주 동안 진행되었으며, 두 그룹의 총 8명의 대상자에게 연구자가 1:1로 각 대상자에게 40분씩 목표 관리 훈련을 실시하였다. 통계방법으로는 기술통계와 빈도분석을 사용하였으며, 두 그룹의 차이를 비교하기 위해 비모수 통계분석인 Mann-Whitney 검정을 실시하였다. 통계학적 유의수준은 0.05로 설정하였다. 결과: 목표관리 훈련은 두 그룹에서 COPM의 수행도에서는 통계학적으로 유의하게 차이가 없었다(p>.05). 목표 관리훈련은 운동기능을 평가하는 BOT-2의 총점에서 자페스펙트럼 장애 그룹과 정상아동 그룹 간에 통계적으로 유의한 차이가 있었다(p<.05). 또한 시지각 기능을 평가하는 DTVP에서도 양측 활동을 하는 눈손협응 하위검사에서 자폐스펙트럼 아동과 정상아동 그룹간에 통계적으로 유의한 차이가 있었다(p<.05). 결론: 본 연구는 정상아동과 비교하여 자페스펙트럼 아동에게 목표관리 훈련을 적용가능성을 확인하였으며, 그 효과성도 확인하였다.

• 농촌의학ㆍ지역보건
• /
• 제45권4호
• /
• pp.208-220
• /
• 2020

본 연구는 해양경찰공무원의 외상 후 성장에 영향을 미치는 요인을 규명하고자 하였다. 연구대상은 2019년 6월 17일부터 7월 31일까지 해양경찰교육원에서 기본 교육 및 전문교육을 받은 해양경찰관 293명을 대상으로 시행되었다. 자료는 SPSS version 21.0 프로그램을 이용하여 빈도와 백분율, 평균과 표준편차, t-검정과 분산분석, 피어슨의 상관분석과 다중회귀분석으로 분석하였다. 연구결과 해양경찰공무원의 외상 후 성장은 평균 39.72±16.56점이었고, 회복탄력성 평균 84.46±9.85점, 사회적지지 평균 86.16±16.21점, 집단문화 9.50±2.26점, 합리문화 10.79±1.94점, 발전문화 9.61±1.95점, 위계문화 10.96±2.00점이었다. 외상 후 성장에 영향을 미치는 요인을 살펴보면 결혼여부(β=0.194, p=0.002), 흡연여부(β=0.152, p=0.010), 규칙적인 운동여부(β=-0.185, p<0.001), 총 근무기간(β=-0.154, p=0.033), 회복탄력성(β=0.310, p<0.001), 사회적지지(β=0.250, p<0.001), 집단문화(β=0.158, p=0.004)가 외상 후 성장에 영향을 미치는 요인으로 확인되었고, 이들 변수의 설명력은 56.5%이었다. 본 연구 결과로 해양경찰공무원의 외상 후 성장은 개인적인 특성 뿐 아니라 가족과 동료들의 지지, 근무 환경 및 문화에 의해 영향을 받았다. 향후 스트레스의 완화를 위한 조직 차원의 관리가 적극적으로 시행되어야 하며, 가족 및 동료와의 유대감을 강화하고 친근한 분위기가 형성될 수 있는 근무환경 및 문화의 변화가 이루어지면 외상 후 성장을 높일 수 있을 것으로 사료 된다.