• 운동영양학회지
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• 제23권1호
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• pp.13-20
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• 2019

[Purpose] The OPG/RANK/RANKL signaling is a new family of bone metabolism biomarkers belonging to the immune system. However, the bone metabolism response to long-term exercise in the RANKL/RANK/OPG signaling is less evident. The purpose of this study was to examine these biomarkers in healthy college females after 12-weeks combined exercise intervention. [Methods] Participants (N=22, 22.4±1.3yrs) were randomly divided in two different group: 12 in the control group and 10 in the exercise group performing combined exercise program that interventions was conducted 3 times per week for 12 weeks. The outcome measures included serum concentrations of RANKL, OPG and bone metabolic cytokines such as TNF-α and IL-6, and mRNA expressions of same variables from PBMC. VO_2max and bone mineral density (BMD) were measured at before and after exercise intervention. [Results] There were no significant differences in the serum RANKL, OPG concentrations and all RANKL/RANK/OPG signaling mRNA expression on interaction effect between group and time (NS). Also no significant differences were found in the serum TNF-α and IL-6 concentrations and mRNA expression (NS). The IL-6 mRNA expression only showed significant difference in the main effect of groups (p<.05). There were also no significant differences in the VO_2max and BMD on interaction effect between group and time (NS). [Conclusion] These results suggested that there were no effects on bone mineral density and RANKL/RANK/OPG signaling without the effect of 8-weeks combined exercise on cardiovascular endurance fitness.

• 운동영양학회지
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• 제16권2호
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• pp.93-100
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• 2012

Alzheimer's disease (AD) is the most common cause of dementia in adults. Microtubule associated protein tau is abnormally phosphorylated in AD and aggregates as paired helical filaments (PHFs) in neurofibrillary tangles (NFTs). NFTs are the most common intraneuronal inclusion in the brains of patients with AD and have been implicated in mediating neuronal cell death and cognitive deficit. Aberrant phosphorylation of tau is an early pathological event in AD, but the underlying mechanisms are unclear. MAP kinases are a family of Serine/Threonine (Ser/Thr) kinases that involved hyper - phosphorylation of tau in AD. The purpose of this study was to investigate the effect of treadmill exercise on phosphorylation of tau level and activation of MAPKs including JNK, ERK, p38-MAPK. To address this, Tg mouse model of AD, Tg-NSE/hTau 23, which expresses human tau 23 in the brain, was chosen. Animals were subjected to treadmill exercise for 12 weeks from 24 months of age. Treadmill exercise in Tg group improved cognitive function compared with Tg-SED group in watermaze test. In addition, treadmill exercised Tg mice significantly reduced the activation of JNK54/46, p38-MAPK and tau (Ser404, Ser202, Thr231), and increased activation of ERK44/42 in cerebral cortex. These results suggest that treadmill exercise may provide a therapeutic potential to alleviate the tau pathology like AD.

• 한국전문물리치료학회지
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• 제18권3호
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• pp.38-48
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• 2011

The aim of the study was to identify which fall-prevention program offered in community settings in Korea is the most effective in strengthening muscles. Muscle weakness is one of the major risk factors causing falls among the elderly. Randomized controlled trials and clinical controlled trials published between 1996 and February 2011 were included in this study. Seventeen of the 69 identified studies met the study's criteria and were included in this meta-analysis. The overall effect size of the program was .822 (95% confidence interval= .717~.927). The general strengthening exercise (1.608), dance sports training (1.538), Thera-band exercise for lower extremities (1.517), Seniorobic exercise (1.146), gait training (.959), balance training (.909), gradual resistive exercise (.888), and multifactorial fall prevention (.842) programs all show positive effects on muscle strengthening. Subgroup analyses found that more relative effects are seen in programs offered to the more elderly. In this study, the effect of increasing muscle strength on the prevention of falls can only be indirectly suggested; there are few available studies that report the frequency or history of falls in Korea. Further studies are needed to examine the direct effect of fall prevention exercise programs among the elderly.

• 한국지역사회생활과학회지
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• 제19권2호
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• pp.191-199
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• 2008

The purpose of this study was to obtain an understanding of the effect of regular exercise on obesity indices, the psychosocial wellbeing index, dietary factors and exercise regularity among 146 healthy mothers and 146 their daughters. "Mother" subjects were divided into two groups classified as regular exercise group(REG) and none exercise group(NEG). The exercise regularity of REG's daughters(30.8%) and of NEG's daughters (2.0%) was significantly different(p<0.001). The Obesity Indices(Body Mass Index (BMI), Waist Hip Ratio(WHR) and Percentage of Ideal Body Weight(PIBW)) of NEG's daughters were significantly higher than those of REG's daughters(p<0.001). But the psychosocial wellbeing index was not significantly different between REG's daughters and NEG's daughters. Intake of total energy, protein, fat, Ca, niacin and Fe were significantly different(p<0.001) between REG's daughters and NEG's daughters. Especially, vitamin C intake of REG's daughters was significantly higher than that of NEG's daughters(p<0.001). The exercise regularity of mothers was mainly related with Obesity Indices and nutrient intake in their daughters. Therefore, it might be necessary to maintain exercise regularity to prevent obesity and diet related problems in mothers and their daughters.

• 대한간호학회지
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• 제39권4호
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• pp.584-593
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• 2009

Purpose: The purpose of this study was to investigate the effect of stretching, muscle strengthening, and walking exercise on the cardiopulmonary function and health-related quality of life in hemodialysis patients. Methods: Twenty-one patients in the intervention and the control group participated in the exercise respectively on maintenance hemodialysis at four university hospitals. The exercise was composed of 20 to 60 min per session, 3 sessions a week for 12 weeks. The effect of exercise was assessed by cardiopulmonary function (peak oxygen uptake, peak ventilation, peak respiration rate, maximal heart rate, and exercise duration) using a cycle ergometer. Grip strength was measured by dynamometer, and flexibility was measured by sit and reach measuring instrument. Health-related quality of life was measured using Medical Outcomes Study Short Form-36. Results: Peak oxygen uptake, peak ventilation, peak respiration rate, exercise duration, grip strength, flexibility, and physical component scale were significantly improved in the intervention group after 12 week's exercise compared to the control group. Conclusion: These findings indicate the exercise can improve cardiopulmonary function, grip strength, flexibility, and physical component scale of health-related quality of life in hemodialysis patients.

• 대한물리의학회지
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• 제8권4호
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• pp.479-487
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• 2013

PURPOSE: The purpose of this research was comparing and analyzing the exercise effect for the public who was not suffering back pain exercise in improving the waist flexibility, the waist muscular strength and the waist sense of equilibrium after grafted in William & McKenzie exercise with swiss ball. METHODS: 16 people who were not in progress of the chronic low-back pain were recruited. They were grouped into 8 for each experiment(GSBE=Group which play swiss ball exercise, GWME=Group which William & McKenzie exercise). RESULTS: The following result was obtained through measurement of three items in both pre and post examination. CONCLUSION: Comparing the average result of flexibility improvements of each group after 12-week exercise program, the result showed that GSBE was more effective than GWME with increase of muscular strength. Comparing the average result of muscular strength of each group after 12-week exercise program, the result showed that GSBE was more effective than GWME with increase of flexibility improvements. Comparing the average result of sense equilibrium of each group after 12-week exercise program, the result showed that GSBE was more effective than GWME with increase of sense equilibrium.

• 대한물리의학회지
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• 제5권4호
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• pp.667-674
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• 2010

Purpose : The purpose of this study was to investigate the effect of motion-based game exercise program and stretching exercise program on static and dynamic standing balance in elderly women. Methods : Subjects participated in the exercise program was 40 eldery women took part in this study. The average age of the elderly was 70.60 years. All subjects could walk without an assistive device. All subjects were participated in this study during 4 weeks(3 days per week, 30min/day). All participants were assessed on berg balance scale(BBS), functional reach test(FRT), timed up&go test(TUG). Results : The data were analyzed using paired t-test. After 4 weeks exercise training, the result of this study were as follows: The BBS of the elderly was significant difference between test-retest(p<0.05). The TUG of the elderly were significant difference between test-retest(p<0.05). The Motion-Based game from FRT of the was more significant difference than stretching exercise program(p<0.05). we also found significant differences for both groups FRT scores, and changes in mean BBS, TUG scores, but BBS, TUG were not significant. Conclusion : We findings suggest that elderly women person could improve their standing balance through Motion-Based game exercise program, and stretching exercise program.

• 지역사회간호학회지
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• 제18권1호
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• pp.56-68
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• 2007

Purpose: The present study analyzed the contents of exercise programs for the elderly in Korean and foreign articles. Method: This study analyzed 27 Korean and 20 foreign exercise-related articles selected from Web DBs using keywords 'exercise', 'exercise program' and 'exercise effect'. The collected data were analyzed using SPSS 11.5 through descriptive statistics, $x^2$ test and Fisher's exact test. Results: In the description of population, random sampling and informed consents, foreign articles were higher than Korean articles. In research design, foreign articles randomized controlled trials (RCTs) higher than Korean articles. The contents of exercise programs in the Korean and foreign articles were aerobic, walking and stretching. On the effects of exercise programs in the Korean articles, walking showed the highest frequency in the physical strength as well as muscle strength, balance and flexibility. In the foreign articles, walking and stretching showed high frequency in physical strength. Conclusion: Contents significant in exercise programs for the elderly were walking and stretching. In addition, regular exercise had a positive effect on muscle strength, flexibility and balance in the elderly.

• 한국응용과학기술학회지
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• 제37권5호
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• pp.1314-1322
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• 2020

Sports drinks help optimize and improve performance by delaying and eliminating the buildup of fatigue-causing substances in the body during exercise. Saengmaeg-san is a nature-friendly traditional beverage that has no side effects on the human body and can quench thirst. However, studies on the relationship between exercise ability and Saengmaeg-san are insufficient. The purpose of this study was to prescribe Saengmaeg-san during the summer training period of 4 weeks and to analyze the effect on body composition and exercise performance. Seventeen male participants were divided into 3 groups (Saengmaeg-san acid intake group [n=9], placebo group [n=8]), and body composition (height, weight, muscle mass, fat mass, BMI) and conducted exercise performance (total exercise time and HRmax). In our study, Saengmaeg-san intake had a positive effect on exercise performance, such as decreased body fat percentage, increased exercise time, and decreased HRmax. Therefore, Saengmaeg-san showed the potential as a sports drink. In the future, additional studies on fatigue-related substances, immune function-markers, and blood lipids are needed in order to clearly explain the change in exercise performance due to consumption of Saengmaeg-san.

• 대한물리치료과학회지
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• 제17권3_4호
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• pp.23-28
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• 2010

Purpose: Hyperglycemia is associated with an risk of cardiovascular disease, mortality, diabetes mellitus and musculoskeletal disorders. The purpose of this study was to analyse the effect of two different treadmill exercise on blood levels of glucose in SD rats. Methods: The experimental groups were divided into 2 groups. The exercise was performed in the treadmill for 20minutes with 15m/min(group I, n=20) and 25m/min(group II, n=20) Blood samples were collected before exercise, 6day and 12days after treadmill exercise. Results: A significant difference was only at 12days on independent samples t-test for both groups. There were statistically significant difference between pre and 6days, 6days and 12days, pre and 12days on tests of pairwise comparisons for each groups. Both group were showed linear effects following treadmill exercise in 12days. Conclusion: These results suggest that a trend toward decrease in the levels of glucose, following treadmill exercise, were revealed in both group. Aerobic exercise related to a positive effect in control of glucose level.