• 한국응용과학기술학회지
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• 제40권3호
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• pp.385-391
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• 2023

본 연구는 혈중 비타민 E 농도와 대사증후군의 관련성을 살펴보고 비타민 E의 신체에 미치는 영향을 살펴보고자 한다. 분석 자료는 질병관리본부에서 시행한 국민건강영양조사 제7기 3차 (2018년도) 자료를 사용하였으며 본 연구에서는 만 19세 이상 성인은 대상으로 혈중 비타민 E의 농도를 검사한 대상자 중 남자 944명, 여자 1,080명을 최종 분석하였다. 자료 분석은 일반적 특성에 따른 혈중 비타민 E 농도 차이는 Chi-square와 t- test로, 혈청 비타민 E 농도와 대사증후군 하부요인들 간의 관계는 Pearson 상관관계로, 혈중 비타민 E 농도와 관련된 대사증후군 지표는 로지스틱 회귀분석을 하였다. 대사증후군의 하부요인과 혈중 비타민 E의 회귀분석 결과 HDL-cholesterol이 정상군이 과잉군에 비해 높았으며(OR:1.042, CI:1.028-1.056), 중성지방도 정상군에 비해 유의미하게 높았다(OR:1.010, CI:1.009-1.012)(p<0.01). 따라서 본 연구를 통하여 환자의 연령에 맞는 영양 및 건강프로그램을 개발할 것을 제안한다.

• Nuclear Engineering and Technology
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• 제56권1호
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• pp.207-215
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• 2024

This study focuses on measuring the levels of naturally occurring radioactivity in the soil of Swabi, Khyber Pakhtunkhwa, Pakistan, as well as the associated health hazard. Thirty (30) soil samples were collected from various locations and analyzed for ²²⁶Ra, ²³²Th, and ⁴⁰K radioactivity levels using a High Purity Germanium detector (HPGe) gamma-ray spectrometer with a photo-peak efficiency of approximately 52.3%. The average values obtained for these radionuclides are 35.6 ± 5.7 Bqkg^-1, 47 ± 12.5 Bqkg^-1, and 877 ± 153 Bqkg^-1, respectively. The level of ²³²Th is slightly higher and ⁴⁰K is 2.2 times higher than the internationally recommended limit of 30 Bqkg^-1 and 400 Bqkg^-1, respectively. Various parameters were calculated based on the results obtained, including Radium Equivalent (Ra_eq), External Hazard (H_ex), Absorbed Dose Rate (D), Annual Gonadal Equivalent Dose (AGDE), Annual Effective Dose Rate, and Excess Lifetime Cancer Risk (ELCR), which are 170.3 ± 24 Bqkg^-1, 0.46 ± 0.06 Bqkg^-1, 81.4 ± 2.04 nGy h^-1, 582 ± 78.08 µSvy^-1, 99.8 ± 13.5 µSv Gy^-1, and 0.349 ± 0.04, respectively. These values are below the limits recommended by the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) in 2002. This study highlights the potential radiation threats associated with natural radioactivity levels in the soil of Swabi and provides valuable information for public health and safety.

• Nutrition Research and Practice
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• 제9권4호
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• pp.404-410
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• 2015

BACKGROUND/OBJECTIVES: Although the association of body mass index (BMI) with metabolic syndrome (MetS) is well documented, there is little knowledge on the independent and joint associations of BMI and physical activity with MetS risk based on a continuous scoring system. This study was designed to explore the effect of physical activity on interactions between excess body weight and continuous metabolic syndrome (cMetS) in a nationwide survey of Iranian children and adolescents. SUBJECTS/METHODS: Data on 5,625 school students between 10 and 18 years of age were analyzed. BMI percentiles, screen time activity (STA), leisure time physical activity (LTPA) levels, and components of cMetS risk score were extracted. Standardized residuals (z-scores) were calculated for MetS components. Linear regression models were used to study the interactions between different combinations of cMetS, LTPA, and BMI percentiles. RESULTS: Overall, 984 (17.5%) subjects were underweight, whereas 501 (8.9%) and 451 (8%) participants were overweight and obese, respectively. All standardized values for cMetS components, except fasting blood glucose level, were directly correlated with BMI percentiles in all models (P-trend < 0.001); these associations were independent of STA and LTPA levels. Linear associations were also observed among LTPA and standardized residuals for blood pressure, high-density lipoprotein, and waist circumference (P-trend < 0.01). CONCLUSIONS: Our findings suggest that BMI percentiles are associated with cMetS risk score independent of LTPA and STA levels.

• 보건교육건강증진학회지
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• 제20권1호
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• pp.159-172
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• 2003

Purpose : The purpose of this study was to investigated the dietary habits of students in order to identify risk groups according to their Body Mass Index (BMI), and to compare the eating behavior of students in the normal range (19${\le}$24) and those in risk groups (BMI${\le}$19, 24${\le}$27, BMI>27). Method : 1176 elementary school students, 850 middle school students and 672 high school students in Wonju City, were the participants The instrument for this study was a structured questionnaire that included demographic data as well as dietary habits, and the eating behavior instrument developed by Stunkard & Messick(1985) and revised by Kim & Kim (1997). Result : 1) As students moved up ingrade level their dietary habits became more irregular and the degree that students chewed food was reduced 2) As students moved up in grade level, a greater number of the student did not eat breakfast. The reasons given were that there were not enough time before classes started(40.4%) and a lack of appetite in the morning(10.6%) in high school students. 3) As for supper, from 67.8 to 81.9% of subjects reported having regular supper. However the rest of the subjects did not eat supper because of anorexia and fear of weight gain. 4) The results identified risk groups according to their BMI showed that for elementary school students, 55.9% were in the low weight group, 5.5% in the overweight group, and 0.9% in the obese group. For middle and high school students, 40.6% and 35.5% respectively were in the low weight group, 7.4% and 6.3% in the overweight group, and 4.1% and 2.5% the obese group. 5) Comparisons of the eating behavior of students in the normal weight group with that of those in the three risk groups showed that there significant differences in 'hunger' and cognitive restraint of eating' in elementary school students, and significant differences in 'cognitive restraint of eating' in middle and high school students. Conclusion : The results of this study show that management of diet in school health should be addressed from both the aspect of lack of nutrition and that of excess nutrition. In other words, good diet is as important for students in the low weight group as it is for those in the overweight and obese groups. The establishment of good dietary habits and eating behavior in students, by nurses and dieticians should be done by providing repeated diet education and involvement in diet counseling.

• 환경영향평가
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• 제28권2호
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• pp.152-168
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• 2019

비소는 암 등의 질병 치료 및 생활용품 등의 원료로 사용되는 등 산업 활동 전반에 걸쳐 다양한 용도로 사용되어 온 원소이다. 그러나 토양 매립 폐기물 처리, 금속 제조 및 화석 연료의 사용 등으로 인해 환경 생태계를 오염시킬 수 있다. 특히 비소는 토양 및 미생물에 의한 자연적 요인과 산업활동과 같은 인위적 요인으로 발생 할 수 있어 환경매체 중에 광범위하게 존재하기 때문에 다른 원소에 비해 인체에 노출될 가능성이 크다. 따라서 본 연구는 기존의 단순농도 평가 및 단일 매체 중심의 오염원 관리의 단점을 극복하기 위해 다경로(흡입, 경구, 접촉 등)/다매체(대기, 수질, 토양 등) 거동 특성을 반영하여 인체 위해성 평가를 수행하였다. 결과적으로 노출경로별 비소가 인체에 가장 많이 노출되는 경로는 경구에 의한 기여도로 57~96 %를 차지했다. 상대적으로 다른 연령군에 비해 영유아에서 높은 노출량을 보였다. 이는 성인에 비해 체중이 적고 체표면적이 커서 유해물질에 더 많이 노출 될 수 있기 때문이다. 기존 연구에서 보고된 바와 같이, 비소는 경구 경로 중 먹는물의 기여도가 대부분의 연령층에서 주요 노출 경로를 보였다. 최종적으로 노출량 평가 결과에 근거하여 발암위해도 및 비발암위해도를 산정하였다. 산정결과 CTE 및 RME에 대한 발암위해도는 2.3E-05~6.7E-05의 범위로 모든 연령 군의 전체 시나리오에서 발암확률 1.0E-04을 초과하지 않았으므로, 발암위해를 무시할만한 수준으로 판단된다. 반면 RME에 대한 발암위해도는 6.4E-05~1.8E-04의 범위로써 영유아 및 미취학아동 군에서 1.3E-04~1.8E-04의 범위로 초과발암확률 1.0E-04을 초과하였다. CTE 및 RME에 대한 비발암위해도 결과는 위해지수가 각각 5.4E-02~1.9E-01, 1.5E-01~6.8E-01의 범위로 모든 연령 군의 전체 시나리오에서 위해지수 1을 초과하지 않았으므로, 비발암 위해성은 낮은 것으로 판단된다.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2011년도 정기총회 및 추계학술대회 논문집
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• pp.881-895
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• 2011

Seoul Metro railway facilities' inspection and maintenance tasks cause failure analysis, but if there is trouble the diverse cause investigation and the systematic analysis and management among broken facilities, related facilities and components fell short and the conditions are different. And, excess and insufficiency, under inspection and maintenance, is being raised regardless of the introduction year and the operating environment including the number of use by applying the same facilities in the uniform inspection cycle. In this study, we will analysis systematically facility system information, failures, operational status, performance, fault and maintenance information resulting from the maintenance management of railway facilities and derive the relationship between associated equipment and its components. In addition, optimizing the inspection and the maintenance cycles of railway facilities, we will improve the reliability of operation. Considering the probability of risk, it is possible to predict the occurrence of accidents or faults and to minimize the frequency of breakdown by pre-inspection maintenance. Finally, This paper is to introduce the content of constructing the Seoul Metro RCM-based failure analysis system for railway facilities to support the optimal continuance of operation status of equipments and the securement of the safe operation of vehicles.

• 한국건강관리협회지
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• 제2권3호
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• pp.73-96
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• 2004

Along with a development of medical technology, a variety of tests, such as laboratory tests, x-ray and endoscopies are being used in health screening tests. As the tests determine the quality of health screening, test items and methods should be carefully selected. This study was to get hold of the test items of major health screening programs in Korea Most of the health screening programmes focused upon detection of risk factors and diagnosis of life - style related diseases (diabetes, hypertension, cardiovascular diseases, hypercholesterolemia, overweight, drinking, smoking, cerebrovascular diseases, osteoporosis) ,cancers (stomach, cervix, lung, breast, liver, colon, prostate, ovary, pancreas, thyroid, esophagus) , infectious diseases (hepatitis, tuberculosis, sexually-transmitted diseases, parasites) , chronic obstructive respiratory diseases, chronic renal diseases (bacteriuria hematuria, proteinuria) , anemia, glaucoma, hearing loss, Alzheimer disease, stress, early psychiatric diseases. The health screening tests were basic physical examination, basic laboratory tests (CBC, urinalysis, liver function tests, lipid tests, glucose, HbAlc, uric acid, electrolytes, serological tests (HBsAg, HBs-Ab, HCV-Ab, HIV-Ab, VDRL) EKG, x-ray (chest PA, CT) , endoscopy (gastroscopy, colonoscopy) , sonography(abdomen, thyroid, pelvis, breast) ,cytology (cervix) , bone density, tumor markets (NMP22, alpha-FP, CEA, CA-19-9, CA12S, PSA) and eye tests. Advanced technologies, like CT, PET, MRI, MRT/Angio, molecular testings) were widely used in hospital health screening programmes .In summary, a variety of tests were utilized in health screening in Korea. Those tests were utilized by stages or according to sex and age in most of health screening programmes, however a few program used tests to excess disregarding health screening subjects.

• Journal of Microbiology and Biotechnology
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• 제10권4호
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• pp.441-448
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• 2000

The production and cation flux-mediated activation of the P-type ATPase in Helicobacter pylori was investigated. Using the polymerase chain reaction (PCR), the proton pump genotype of H. pylori was found to be positive for both F-type and P-type ATPases. Yet, their production in terms of enzyme specific activity varied substantially depending on H. pylori strains, ranging over 3-fold. Its main constituent appeared to be the P-type ATPase pool, in contrast to other common bacterial compositions. Interestingly, the F-type ATPase was observed only when intact H. pyloricells were exposed to pH 4.5 or above (37$^{\circ}C$ for 1 h). In contrast, significant amounts of the P-type ATPase still remained after 1 h of cell treatment even at pH below 4.5. By enriching the acidic medium with RPMI(pH 3.0), the P-type ATPase was stabilized, accompained by inactivation of the F-type ATPase. Using H. pylori membrane vesicles, it was found that ammionia-mediated cation flux increased the rate of ATP hydrolysis by the P-type ATPase. Accordingly, these data strongly suggest that the P-type ATPase is involved or functions as an effective regulator for the cation flux across the H. pylori membrane, thereby reducing the risk of excess proton influx.

• Structural Monitoring and Maintenance
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• 제7권1호
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• pp.1-12
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• 2020

Railway tracks are the direct supporting structures of the trains, which are vulnerable to produce large deformation under the temperature stress or subgrade settlement. The health status of track is critical, and the track should be routinely monitored to improve safety, lower the risk of excess deformation and provide reliable maintenance strategy. In this paper, the distributed optical fiber sensor was proposed to monitor the continuous deformation of the track. In order to validate the feasibility of the monitoring method, two deformation monitoring tests on one steel rail model in laboratory and on one real railway tack in outdoor were conducted respectively. In the model test, the working conditions of simply supported beam and continuous beam in the rail model under several concentrated loads were set to simulate different stress conditions of the real rail, respectively. In order to evaluate the monitoring accuracy, one distributed optical fiber sensor and one fiber Bragg grating (FBG) sensor were installed on the lower surface of the rail model, the strain measured by FBG sensor and the strain calculated from FEA were taken as measurement references. The model test results show that the strain measured by distributed optical fiber sensor has a good agreement with those measured by FBG sensor and FEA. In the outdoor test, the real track suffered from displacement and temperature loads. The distributed optical fiber sensor installed on the rail can monitor the corresponding strain and temperature with a good accuracy.

• 한국압력기기공학회 논문집
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• 제16권1호
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• pp.22-29
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• 2020

In nuclear power plants, there is a risk of thermal fatigue in equipment and piping affecting system soundness because the temperature change of the system accompanies in every operation and shutdown. Therefore, in order to prevent the excess of the fatigue limit during the lifetime of plants, the fatigue limit of each piping material is determined in the designing stage. However, there are many cases where equipment or piping is locally subjected to thermal fatigue that is not considered in the design, resulting in damage to the equipment and piping, and failure during operation. Currently, local thermal fatigue generation mechanisms that are not taken into account in the design stage are gradually being identified. In this paper, the effects of the fluid temperature fluctuations on the piping soundness due to the mixing of hot and cold water, one of the local thermal fatigue generating mechanisms, were evaluated.