• 동의신경정신과학회지
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• 제22권3호
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• pp.101-113
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• 2011

Objectives : Trend of R&D of herbal medicine for dementia treatment was examined based on the quantitative information analysis for establishing the national strategy of research on dementia treatment with oriental medicine. Methods : Definition was made to clarify the technology for development of herbal medicine for dementia treatment. Based on the initial keyword provided by experts in the field, queries were compounded to conduct search in the search engines of WoS and DWPI. The raw data (papers or patents) extracted from the initial search were examined by expert-review before objects of analysis were determined. Then, the accumulated data was analyzed in terms of year, country and organization, which led to examination of the trend of R&D. And the research performance evaluation for dementia treatment technologies was also made in terms of country, organization and researcher based on the forward citation analysis. The international cooperation intensity was examined on the basis of analysis of network by researcher before analysis results were put together to select lead researchers. Results : According to the quantitative information analysis of 1,330 articles that were selected as analysis objects, the number of papers on natural products research for dementia treatment has increased by around 4.6 times in recent five years. This indicates that the intensive studies have been underway recently. It was found to be the US that had the highest level in research filed of herbal medicine for dementia treatment and the highest capacity of international cooperation for that purpose. On the contrary, Korea had the share of papers at 5.1%, the number of countries in cooperation research at 8, and the article quality index at 0.40, showing that the qualitative level was insufficient, compared to the quantitative outcome. In particular, Korea was found to have no intensity of international cooperation among researchers. In case of patent, the results of information analysis of 305 patents selected as analysis objects demonstrated that China had the highest share while Korea had the very low frequency of patent application quantitatively. Conclusions : In this study, the research to develop herbal medicine for dementia treatment has recently drawn much attention that has spread around the globe. Therefore, these results suggest establishing the strategy to develop technology for dementia treatment with oriental medicine in the future based on quantitative information analysis.

• 한국수학사학회지
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• 제25권3호
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• pp.119-140
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• 2012

본 연구는 교육과정 평가원이 제시한 수학과 교과 내용학 평가 영역 및 평가 내용 요소에 따라 2009학년도부터 2012학년도까지, 중등교사 임용시험에서 출제된 수학과 교과 내용학의 문항을 분석한 것이다. 연구의 목적을 달성하기 위해 4년간 출제된 수학과 교과내용학의 105 문항을 수집하여, 9개 과목 간, 평가 영역 및 평가 내용 요소에 따라 출제된 비율을 분석하였고, 그 결과를 토대로 사범대학 수학교육과 교육과정의 운영이나 평가영역의 재조정에 대한 시사점을 도출하였다. 연구 결과 수학과 내용학의 9과목 간 출제비중에 있어서 현저한 차이가 있으며, 과목별 평가 영역 간에도 출제 비중에 있어서 큰차이가 있는 것으로 나타났다. 평가 내용 요소의 분석에 있어서도 262개 중에서 153개가 4년동안 교사 임용시험에 출제되지 않은 것으로 나타났다. 이러한 분석 결과에 근거하여 수학과 내용학의 출제 과목간의 비중이나 평가 영역 및 평가 내용 요소의 재 조정에 대한 필요성을 논의하였다.

• 디지털융복합연구
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• 제20권5호
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• pp.221-226
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• 2022

본 연구의 목적은 비대면 소비문화에 초점을 맞추어 라이브커머스 이용자의 차별화된 동기를 탐색하고자 하며 라이브커머스 이용동기와 태도와의 영향 관계에서 인게이지먼트의 매개효과를 검증하는 것이다. 연구방법은 라이브커머스 이용자를 대상으로 온라인 설문조사를 진행하였으며 245부의 유효표본을 분석에 활용하였다. 자료분석은 탐색적 요인분석, 신뢰도분석, 다중회귀분석, 매개회귀분석을 실시하였다. 분석결과, 라이브커머스 이용동기는 상호작용의 쾌락성, 직접 검수의 대체 가능성, 커뮤니티의 필요성, 트렌드 추구성 등 4개 요인으로 도출되었다. 이용동기는 인게이지먼트에 유의한 영향을 미치는 것으로 나타났으며 인게이지먼트는 태도에 유의한 영향을 미치는 것으로 나타났다. 마지막으로 인게이지먼트는 라이브커머스 이용동기와 태도와의 관계에서 부분매개효과가 있는 것으로 나타났다. 연구결과는 향후 비대면소비문화에 대한 이해와 라이브커머스 산업의 효율적인 전략 수립을 위한 시사점을 제공할 것이다.

• 한국의류학회지
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• 제35권4호
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• pp.488-500
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• 2011

This study analyzes medical clothing trends and provides future directions for research. Based on 38 patents in Korea and 221 patents in the USA, the contents of patents were analyzed by year, subject, clothing type, and specific content. The results are as follows. The number of patent applications in Korea and the USA was found to be increasing. The distribution by subject was in the order of patient clothing, medical personnel clothing, and materials for medical clothing. Clothing of various types such as upper garment, bottoms, pajamas, gowns, and jump-suits were observed in patient clothing comparatively. However, gowns occupied a higher portion in medical personnel clothing. Patents in the USA related to patient clothing included patient clothing that provided examination convenience, monitoring patient clothing, patient clothing revising appearance, and patient clothing that assisted in movement. Korean patents related to patient clothing include functional patient clothing, patient clothing providing examination convenience, clothing for Alzheimer patients, and monitoring patient clothing. Many of the patents related to medical personnel clothing were about surgery gowns and mainly concerned with developments related to devices that allows putting on gowns while maintaining a sterile state and functionality to prevent liquid permeation. Regarding materials for medical clothing, there were many applications on breathability and liquid impermeable materials.

• Journal of Preventive Medicine and Public Health
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• 제46권6호
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• pp.353-359
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• 2013

Objectives: We examined the trends in prevalence, awareness, treatment, and control of hypertension in Korea as a basis for improving hypertension control programs. Methods: 12 598 participants of the Korean National Health and Nutrition Examination Survey were included in this study. Weighted linear regression to test time trends from 2007 to 2011 was performed. Results: The prevalence of hypertension was 20.7% in 2007, 29.4% in 2009, and 26.2% in 2011. Awareness of hypertension was 64.8% in 2007 and 61.1% in 2011. Awareness in those aged 65 and over was greater than in younger groups (age 19 to 44 and 45 to 64; p<0.001). The treatment rates were 58.4% in 2007 and 56.8% in 2011. The treatment rate was greater for those 65 and over than for younger age groups (p<0.001). The percentage of controlled hypertension was 37.6% in 2011. The percentage of controlled hypertension in those 65 and over was higher than in younger age groups (p<0.001). The treatment-control rates were 65.9% in 2007 and 67.7% in 2011. The prevalence of hypertension was higher in the males (p<0.001), while the awareness (p<0.001), treatment (p<0.001), and control (p<0.001) rates were higher in the females. Conclusions: The prevalence of hypertension was increasing and the hypertension awareness, treatment, and control rates were low in younger age groups and males.

• Journal of Korean Medical Science
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• 제33권50호
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• pp.320.1-320.8
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• 2018

Background: Muscle mass and muscle function are related to depressed mood in studies of adults. Like adults, Korean students are highly likely to suffer from decreased muscle mass due to social conditions. In this study, we evaluated the muscle mass status of Korean adolescents and assess the effect of muscle on depressive mood. Methods: A total of 1,233 adolescent boys and girls participants from the Korea National Health and Nutrition Examination Survey were enrolled in our study. Participants underwent dual-energy X-ray absorptiometry for assessment of appendicular muscle mass and completed questionnaires regarding depressed mood, stress, suicidal ideations, and attempts. Results: There was no difference in depressive mood according to muscle mass among boys (P = 0.634); girls with decreased muscle mass had a greater tendency for depressed mood compared to girls with optimal muscle mass (P = 0.023). After adjusting for age, waist circumference-to-height ratio, smoking status, alcohol consumption, frequency of physical activity, self-reported obesity, weight-loss efforts, and monthly household income, girls with low muscle mass (LMM) were 2.60 times more at risk of developing depression than girls with normal muscle mass (95% confidence interval [CI], 1.05-6.49; P = 0.040). This trend was similar for girls with LMM with obesity (95% CI, 1.00-11.97; P = 0.049). Conclusion: Adolescent girls who have insufficient muscle mass are more likely to report depressed mood than girls who have ideal muscle mass. Interventions for maintaining proper muscle mass are required.

• 한국임상약학회지
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• 제33권4호
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• pp.290-304
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• 2023

Background: Innovative Alzheimer's disease drugs received approval in the United States in 2021 and 2023. This study aims to assess the safety and efficacy of these novel treatments, elucidate their mechanisms of action, and compare their impact on cognitive function improvement with approved drugs. Methods: We conducted a comprehensive search of pivotal clinical studies related to Alzheimer's disease treatments in PubMed/Medline, Embase, and the Cochrane Library databases from January 1st, 2020 to December 31st, 2022. Meta-analysis was performed using RevMan 5.4 software. Results: A total of 14 studies were included in this systematic review. When compared to the placebo, the new drugs did not exhibit a statistically significant effect on MMSE (Mini-Mental State Examination) (mean difference= -0.04, 95% confidence intervals [CIs]: -0.31, 0.23, N=3662, I²=0%). However, they demonstrated a significant impact on ADAS-cog (Alzheimer's Disease Assessment Scale-Cognitive Subscale) (standardized mean difference= -0.15, 95% CIs: -0.2, -0.1, N=6710, I²=17%). When compared to the approved drugs, the new drugs showed a statistically significantly lower effect on MMSE (test for subgroup difference Chi²=23.13, N = 5870, p<0.00001) but showed only a trend of decreased efficacy on ADAS-cog (Chi²=1.16, N = 8670, p=0.28). Conclusion: New drugs yielded diverse clinical endpoint results compared to the placebo, and in comparison to existing approved drugs, they exhibited lower efficacy in improving cognitive function. The safety profile of these new drugs, as reported in clinical trials, was generally well-tolerated.

• 대한치과교정학회지
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• 제48권4호
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• pp.216-223
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• 2018

Objective: This study is performed to investigate the trend of health care (HC) utilization among cleft lip and/or palate (CL/P) during 2007-2016 by using data from the Korean National Health Insurance Service (KNHIS). Methods: The KNHIS data were reorganized to count a specific patient only once for a specific year. Cleft type (cleft lip [CL], cleft palate [CP], and cleft lip and palate [CLP]), sex, and age at HC utilization were investigated. The study period was divided into the first half (2007-2011) and the last half (2012-2016). The utilization number and rate per 1,000 population were calculated for the total population and for new-born patients. Independent t-test and one-way analysis of variance were used for statistical analyses. Results: The total CL/P population (n = 48,707) comprised 19.2% CLP, 35.5% CL, and 45.3% CP (CLP < CL < CP; p < 0.001). Their HC utilization rate increased from 0.066 in 2007 to 0.118 in 2016. The new-born patient population (n = 7,617) comprised 18.6% CLP, 30.4% CL, and 51.0% CP (CLP < CL < CP; p < 0.001). Their HC utilization rate increased from 1.12 in 2007 to 1.74 in 2016. An examination of the utilization number and rate among new-born patients revealed CP exhibited a female-dominant pattern (all p < 0.01), while CL and CLP exhibited a male-dominant pattern (all p < 0.01). However, utilization number showed no difference by sex and cleft type between 2007-2011 and 2012-2016. Conclusions: These results might serve as a guideline for HC utilization among patients with CL/P.

• 한국실내디자인학회논문집
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• 제15권5호
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• pp.193-201
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• 2006

In according as the social action of women is active, the average life span is longer than male, not only woman's social position is higher, but also the construction of the more professional woman special hospital Is increased. In occasion to the recent woman special hospital, give medical treatment about pediatrics and the breast surgery as well, and the sphere is increasing as compose the variety network, from the health medical center to check the woman's physical to the postpartum care center. The trend of the lobby is arranged the more service area as the concept of the woman hospital is changed, the sphere is increasing. Accordingly, this study research and analyze the service zone and design elements on the focus the lobby of the internal woman special hospital, have an intention of guideline about the interior design of the after woman hospital. As the subject of study, selected the hospital that lobby serves to show the identity of total space, and the woman special hospital that is introduced to the relation journal with architecture or interior design, is opened after 2000 years, below the 100 bed. As the study method, understand the composition of lobby space through floor analysis, examination by the visit, analyzed the arrangement constituent, the design trend. The direction of lobby space mentioned in the study result is that secure the publicness, guarantee the privacy zone, and is important that the adequate arrangement of commercial space contribute to client's mental stability, desire that inflected as the more positive communication place.

• Nutrition Research and Practice
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• 제9권6호
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• pp.658-666
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• 2015

BACKGROUND/OBJECTIVES: The current study examined trends in adherence to dietary recommendations and compared the levels of adherence between diagnosed and undiagnosed subjects with type 2 diabetes mellitus (T2DM) in Korea over the past 14 years. SUBJECTS/METHODS: Data were collected from the 1998-2012 Korea National Health and Nutrition Examination Surveys (KNHANES). Diagnosed diabetes was defined as giving a positive response to questions about awareness of the disease, a physician's diagnosis of diabetes, or medical treatment for diabetes, whereas undiagnosed diabetes was defined as having a fasting glucose level ${\geq}126mg/dl$. Assessment of adherence level was based on 6 components of dietary guidelines, considering meal patterns and intake levels of calories, carbohydrates, vegetable/seaweed, sodium, and alcohol. The participants received 1 point if they met the criteria for each of the 6 components, and the total possible score ranged from 0 to 6 points. Multivariate generalized linear regression was performed, taking into account the complex survey design. RESULTS: Among all diabetic patients aged 30 years or older, the proportion of diagnosed diabetes increased dramatically, from 40.9% in 1998 to 75.9% in 2012 (P for trend < 0.001). The overall adherence levels to dietary recommendations were low and did not significantly differ between diagnosed and undiagnosed subjects with T2DM for all survey years. Several improvements were observed, including increased adherence to maintaining sufficient vegetable/seaweed consumption (increased from 0.12 to 0.16 points) and limiting sodium intake (increased from 0.12-0.13 points to 0.19-0.24 points; P for trend < 0.001), while adherence to maintaining moderate alcohol consumption decreased. CONCLUSIONS: Analysis of data collected by the KNHANES indicates that Korean T2DM patients have poor adherence to dietary recommendations and maintenance of a healthy lifestyle, regardless of disease awareness. This finding suggests that development of practical, evidence-based guidelines is necessary and that provision and expansion of educational programs for T2DM patients is critical after diagnosis.