• 산업융합연구
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• 제20권7호
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• pp.31-36
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• 2022

경쟁우위 확보를 위해 인적자원을 효율적이고 효과적으로 활용하는 인사관리가 필요하다는 인식이 빠르게 확산하고 있다. 팬데믹으로 인해 노동시장과 근로환경이 빠르게 변화하는 상황에서 기업현장에서는 데이터와 같은 근거에 기반한 인사관리에 대한 관심이 확산하고 있다. 이에 본 연구에서는 기업현장에서 인사관리 직무를 수행하고 있는 전문가의 인식에 초점을 두고 데이터 기반 인사관리 실행과 활용 전도에 관해 확인하고자 한다. 연구대상은 경기도 판교에 소재한 IT 서비스 개발/제공 전문기업 3개사 인사기획/관리 직무전문가 3명으로 선정하였으며, 데이터 기반 인사관리 실행현황, 측정/분석 도구와 활용도 수준 파악 등에 집중하였다. 연구방법으로는 근거이론 기반의 개방코딩, 축코딩, 선택코딩 절차를 활용하였다. 심층면담을 통한 연구결과, 기업의 인사관리 측정지표는 사람, 생산성, 문화의 세 영역으로 나누어지며, 활용도가 높은 지표를 영역별로 구분할 수 있었다. 본 연구를 통해 연구대상 기업이 어떠한 측정도구와 메커니즘을 통해 인사관리 기능을 실행하고 있으며, 인사관리 실행 효과성과 효율성을 측정, 분석, 활용에 관한 기업현장의 인식을 확인할 수 있었다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권7호
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• pp.4195-4198
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• 2013

Background and Objective: Though researched for years, the prognostic role of hypoxia-inducible factor 1 alpha (HIF-$1{\alpha}$) in gastric cancer is still controversial. We thus undertook a systematic review to assess the relationship. Method: A systematically literature search of Pubmed, Embase, Web of Science, China Biological Medicine Disc and Cochrane Library was undertaken in February 2013, and the reference lists of articles were retrieved. Results: 12 trials (1,555 participants) were included to assess the association between HIF-$1{\alpha}$ expression and survival. Summary hazard ratios (HRs) were calculated. HIF-$1{\alpha}$ expression was significantly correlated with poor overall survival of gastric cancer patients (HR=1.34, 95%CI: 1.13-1.58; P=0.0009), but not with poor disease free survival of gastric cancer patients (HR=1.67, 95%CI: 0.99-2.82; P=0.06). Conclusion: HIF-$1{\alpha}$ was associated with poor OS, but not DFS, especially for Asian patients. But studies evaluating relationships of HIF-$1{\alpha}$ with OS and DFS in non-Asian gastric cancer patients appear needed.

• 천문학회보
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• 제46권1호
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• pp.27.3-27.3
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• 2021

Supernova (SN) cosmology is based on the assumption that the width-luminosity relation (WLR) in the type Ia SN luminosity standardization would not vary with progenitor age. Unlike this expectation, recent age datings of stellar populations in host galaxies have shown significant correlations between progenitor age and Hubble residual (HR). It was not clear, however, how this correlation arises from the SN luminosity standardization process, and how this would impact the cosmological result. Here we show that this correlation originates from a strong progenitor age dependence of the WLR and color-luminosity relation (CLR), in the sense that SNe from younger progenitors are fainter each at given light-curve parameters x1 and c. This is reminiscent of Baade's discovery of two Cepheid period-luminosity relations, and, as such, causes a serious systematic bias with redshift in SN cosmology. We illustrate that the differences between the high-z and low-z SNe in the WLR and CLR, and in HR after the standardization, are fully comparable to those between the correspondingly young and old SNe at intermediate redshift, indicating that the observed dimming of SNe with redshift is most likely an artifact of over-correction in the luminosity standardization. When this systematic bias with redshift is properly taken into account, there is no evidence left for an accelerating universe, and the SN data now support a decelerating cosmic expansion. Since the SN cosmology has long been considered as the most direct evidence for an accelerating universe with dark energy, this finding poses a serious question to one of the cornerstones of the concordance model.

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1105-1109
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• 2012

Breast cancer is the second most common cancer in women in India and the disease burden is increasing annually. The lack of awareness initiatives, structured screening, and affordable treatment facilities continue to result in poor survival. We present a breast cancer survival scenario, in urban population in India, where standardised care is distributed equitably and free of charge through an employees' healthcare scheme. We studied 99 patients who were treated at our hospital during the period 2005 to 2010 and our follow-up rates were 95.95%. Patients received evidence-based standardised care in line with the tertiary cancer centre in Mumbai. One-, three- and five-year survival rates were calculated using Kaplan-Meier method. Socio-demographic, reproductive and tumor factors, relevant to survival, were analysed. Mortality hazard ratios (HR) were calculated using Cox proportional hazard method. Survival in this series was compared to that in registries across India and discrepancies were discussed. Patients mean age was 56 years, mean tumor size was 3.2 cms, 85% of the tumors belonged to T1 and T2 stages, and 45% of the patients belonged to the composite stages I and IIA. Overall 5-year survival was 74.9%. Patients who presented with large-sized tumors (HR 3.06; 95% CI 0.4-9.0), higher composite stage (HR 1.91; 0.55-6.58) and undergone mastectomy (HR 2.94; 0.63-13.62) had a higher risk of mortality than women who had higher levels of education (HR 0.25; 0.05-1.16), although none of these results reached the significant statistical level. We observed 25% better survival compared to other Indian populations. Our results are comparable to those from the European Union and North America, owing to early presentation, equitable access to standardised free healthcare and complete follow-up ensured under the scheme. This emphasises that equitable and affordable delivery of standardised healthcare can translate into early presentation and better survival in India.

• 천문학회보
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• 제38권2호
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• pp.56.1-56.1
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• 2013

Supernovae type Ia (SNe Ia) cosmology is providing the only direct evidence for the presence of dark energy. This result is based on the assumption that the look-back time evolution of SNe Ia luminosity, after light-curve shape correction, would be negligible. However, the most recent compilation of SNe Ia data shows systematic difference in the Hubble residual (HR) between the E and Sd/Irr galaxies, indicating that the light-curve fitters used by the SNe Ia community cannot quite correct for a large portion of the population age effect. In order to investigate this possibility more directly, we have obtained low-resolution spectra for 30 nearby early-type host galaxies. This data set is used to estimate the luminosity-weighted mean ages and metallicities of host galaxies by employing the population synthesis models. We found an interesting trend between the host galaxy age and HR, in the sense that younger galaxies have positive residuals (i.e., light-curve corrected SNe Ia luminosity is fainter). This result is rather independent of the choice of the population synthesis models employed. Taken at face value, this age (evolution) effect can mimic a large fraction of the HR used in the discovery of the dark energy. This result is significant at 1.4 - 3 sigma levels, depending on the light curve fitters adopted, and further observations and analyses are certainly required to confirm the trend reported here.

• Journal of Microbiology and Biotechnology
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• 제23권9호
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• pp.1287-1292
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• 2013

Extracellular biogenic synthesis of silver nanoparticles with various shapes using the rice bacterial blight bacterium Xanthomonas oryzae pv. oryzae BXO8 is reported. The synthesized silver nanoparticles were characterized by UV-Vis spectroscopy, powder X-ray diffractometry (XRD), scanning electron microscopy, energy dispersive X-ray spectrometry, and high-resolution transmission electron microscopy (HR-TEM). Based on the evidence of HR-TEM, the synthesized particles were found to be spherical, with anisotropic structures such as triangles and rods, with an average size of 14.86 nm. The crystalline nature of silver nanoparticles was evident from the bright circular spots in the SAED pattern, clear lattice fringes in the high-resolution TEM images, and peaks in the XRD pattern. The FTIR spectrum showed that biomolecules containing amide and carboxylate groups are involved in the reduction and stabilization of the silver nanoparticles. Using such a biological method for the synthesis of silver nanoparticles is a simple, viable, cost-effective, and environmentally friendly process, which can be used in antimicrobial therapy.

• 대한간호학회지
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• 제50권6호
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• pp.740-756
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• 2020

Purpose: The purpose of this study was to evaluate the effect on blood pressure (BP) and heart rate (HR) according to aerobic exercise characteristics in adults with hypertension using a systematic review and meta-analysis. Methods: The related researches were selected from PubMed, EMBASE, Cochrane library, CINAHL, PsycINFO, SPORTDiscus and 5 domestic databases up to September 4, 2019. To estimate the effect size, random effect models were used to derive weighted mean differences (WMD) and their 95% confidence intervals (CI) of aerobic exercise on BP and HR. Results: A total of 37 RCTs with 1,813 samples were included. Aerobic exercise was found to significantly reduce systolic BP (WMD, - 8.29 mmHg; 95% CI, - 10.12 to - 6.46), diastolic BP (WMD, - 5.19 mmHg; 95% CI, - 6.24 to - 4.14) and HR (WMD, - 4.22 beats/min; 95% CI, - 5.36 to -3.09). In detail, systolic BP and diastolic BP were significantly decreased in all groups of exercise types, frequency and duration. Systolic BP and diastolic BP were significantly decreased in the moderate and vigorous-intensity group. Exercise characteristics with the most dramatical change in systolic BP were water-based training, moderate-intensity, 3 times a week and 8 to 11 weeks of duration. In diastolic BP, the greatest effect size was over 24 weeks of exercise. Conclusion: Moderate aerobic exercise, especially water-based exercise can be an important part of lifestyle modification for hypertensive patients. Also, it can be recommended in a variety of clinical settings for lowering BP and HR. However, there is insufficient evidence that low-intensity exercise is effective in lowering BP.

• 임상간호연구
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• 제23권1호
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• pp.83-90
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• 2017

Purpose: This study was to develop evidence-based clinical practice guideline in order to prevent contrastinduced nephropathy (CIN) for patients undergoing percutaneous coronary intervention (PCI). Methods: The guideline was developed based on the "Scottish Intercollegiate Guidelines Network (SIGN)". The first draft of guideline was developed through 5 stages and evaluated by 10 experts.(1) Clinical questions were ensured in PICO format.(2) Two researchers conducted a systematic search through electronic database, identifying 170 studies. We selected 27 full text articles including 16 randomized clinical trials, 7 systematic reviews, and 4 guidelines. Quality of each studies were evaluated by the Cochran's Risk of Bias, AMSTAR, K-AGREEII. Among the studies, 11 studies were excluded.(3) The strength of recommendations were classified and quality of recommendations were ranked.(4) Guideline draft was finalized.(5) Content-validation was conducted by an expert group. All contents were ranked above 0.8 in CVI. Results: Evidence-based clinical practice guideline to prevent CIN was dveloped.(1) The guideline for preventing CIN recommends using 0.9% saline.(2) Standardized rate of fluid therapy is 1 to 1.5ml/kg/hr.(3) Execute hydration for 6~12hrs before PCI and after PCI. Conclusion: This study suggests evidence-based clinical practice guideline for preventing CIN which can be more efficiently used in clinical practice.

• 셀메드
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• 제8권3호
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• pp.15.1-15.5
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• 2018

Helminthiasis is one of the most common worm diseases which causes a range of adverse health problems in humans. Ayurveda is one of the most prominent and ancient systems of traditional medicines in India. Most Ayurvedic drugs used against intestinal helminths have been developed by traditional wisdom and therefore lack a proper validation through controlled studies. The aim of the present study was to scientifically validate the in vitro efficacy of three common Indian Ayurvedic anthelmintic drugs, viz. Krimimudgar Ras, Kriminol and Vidangasava in relation to the synthetic broad-spectrum anthelmintic drugs, praziquantel and albendazole. The in vitro testing of Ayurvedic anthelmintics was done against an intestinal cestode, Raillietina sp. and a nematode, Syphacia obvelata, employing 10 mg/ml, 30 mg/ml and 50 mg/ml concentrations of each medicine. The anthelmintic efficacy was judged on the basis of paralysis and mortality time of worms after exposing to these Ayurvedic drugs. Of the three tested Ayurvedic medicines, Krimimudgar ras (KR) showed the most prominent efficacy, against both the cestode and nematode parasites. At 50 mg/ml concentration, KR caused mortality of cestodes in $7.53{\pm}0.15hr$, and of nematodes in $7.61{\pm}0.19hr$. Vidangasava was found to be comparatively less effective against the tested helminth parasites. The results of this study indicate that Ayurvedic formulations do possess significant anthelmintic effects, however, an evidence-based research is required to validate all currently used Ayurvedic anthelmintics, using proper controlled studies.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3465-3470
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• 2014

Background: Previous studies have generated conflicting evidence regarding associations between family history and survival after gastric cancer surgery. In this study, we investigated this question using a meta-analysis. Materials and Methods: To identify relevant studies, PubMed and Embase databases were searched up to June 2013. Two reviewers independently assessed search results and data extraction of included studies. Hazard ratios (HRs) and 95% confidence intervals (CIs) for overall survival (OS) were calculated based on fixed- or random-effects models. Homogeneity of effects across studies was assessed using $x^2$ test statistics and quantified by $I^2$. Results: A total of five studies were selected according to the inclusion criteria. The total number of patients included was 2,030, which ranged from 145 to 598 per study. There was no significant difference in OS by family history of cancer (HR=0.83, 95%CIs=0.50-1.38), but subgroup analysis of patients with a first-degree family history of cancer (HR=0.74, 95%CIs=0.60-0.93) and gastric cancer family history (HR=0.56, 95%CIs=0.41-0.76) tended to show better OS in these patients. Conclusions: This meta-analysis suggests that a first-degree family history of cancer or gastric cancer family history is associated with better survival of gastric cancer patients after surgery, after a systematic review of five previous studies. These results can be applied by clinicians when counselling patients regarding their risk of death from gastric cancer. Further study is needed to investigate the underlying mechanism between family history and survival in gastric cancer patients.