Background: We investigated changes in the International Normalized Ratio (INR) and its measurement interval in patients with thromboembolic events who were treated by low intensity anticoagulation therapy after isolated mechanical aortic valve replacement. Materials and Methods: Seventy-seven patients who underwent surgery from June 1990 to September 2006 were enrolled in the study and observed until August 2008. The patients were followed up at 4~8 week intervals and their warfarin (Coumadin)$^{(R)}$ dosage was adjusted aiming for a target range of INR 1.5~2.5. The rate of thromboembolic events was obtained. Changes in the mean INR and INR measurement interval were comparatively analyzed between the normal group (event free group, N=52) who had no anticoagulation-related complications and the thromboembolic group (N=10). Hospital records were reviewed retrospectively. Results: The observation period was 666.75 patient-years. Thromboembolic events occurred in 10 patients. The linearized occurrence rate of thromboembolism was 1.50%/patient-years. Actuarial thromboembolism-free rates were $97.10{\pm}2.02%$ at 5 years, $84.30{\pm}5.22%$ at 10 years, and $67.44{\pm}12.14%$ at 15 years. The percentages of INR within the target range and mean INR were not statistically significantly different for the normal and thromboembolic groups. However, the mean INR during the segmented period just before the events showed a significantly lower level in the thromboembolic group (during a 4 month period: normal group, $1.86{\pm}0.14$ vs. thromboembolic group, $1.50{\pm}0.28$, p<0.001). The mean intervals of INR measurement during the whole observation period showed no significant differences between groups, but in the segmented period just before the events, the interval was significantly longer in thromboembolic group (during a 6 month period: normal group, $49.04{\pm}9.47$ days vs. thromboembolic group, $65.89{\pm}44.88$ days, p<0.01). Conclusion: To prevent the occurrence of thromboembolic events in patients who receive isolated aortic valve replacement and low intensity anticoagulation therapy, we suggest that it would be safe to maintain an INR level above 1.8 and to measure the INR at least every 7~8 weeks.
This study was conducted to find out the soil $CO_2$ emission characteristic due to rain fall pattern and intensity changes. Using Automatic Opening and Closing Chambers (AOCCs), we have measured annual soil respiration changes in Pinus koraiensis plantation at Seoul National University experimental forest in Mt. Taehwa. In addition, we have monitored heterotrophic respiration at trenching sites ($4{\times}6m$). Based on the one year data of soil respiration and heterotrophic respiration, we observed that 24% of soil respiration was derived from root respiration. During the rainy season (end of July to September), soil respiration at trenching site and trenching with rainfall interception site were measure during portable soil respiration analyzer (GMP343, Vaisala, Helsinki, Finland). Surprisingly, even after days of continuous heavy rain, soil water content did not exceed 20%. Based on this observation, we suggest that the maximum water holding capacity is about 20%, and relatively lower soil water contents during the dry season affect the vital degree of trees and soil microbe. As for soil respiration under different rain intensity, it was increased about 14.4% under 10 mm precipitation. But the high-intensity rain condition, such as more than 10 mm precipitation, caused the decrease of soil respiration up to 25.5%. Taken together, this study suggests that the pattern of soil respiration can be regulated by not only soil temperature but also due to the rain fall intensity.
Journal of Korean Society of Environmental Engineers
/
v.27
no.7
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pp.777-784
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2005
The first flush phenomenon is defined as the initial period of road runoff during which the concentration of pollutants was significantly high. Road runoff contains significant loads of micro-particles, heavy metals and organic constituents. There were two major objectives of this study. The first objective was to characterize the road runoff. The second objective was to measure and evaluate particle sire distribution of the road runoff, Stormwater runoff was monitored on two sites of four lane road areas along with traffic volume. A total six storm events were monitored to characterize the road runoff. The quantity of road runoff and quality constituents, including chemical oxygen demand ($COD_{Cr}$), suspended solids(SS), total Kjeldahl nitrogen (TKN), ortho-phosphorus ($PO_4-P$), total phosphorus(TP), heavy metals and particle size distribution were analyzed. The results indicate that the concentration of SS, $COD_{Cr}$, TKN and TP ranges were $45{\sim}2,396\;mg/L$, $40{\sim}931\;mg/L$, $0.1{\sim}19.6\;mg/L$, and $0.2{\sim}25.1\;mg/L$, respectively. The results of the regression analysis between SS and the others constituents shows that $COD_{Cr}$, TP, Cu, Pb were highly correlated. And the results showed that the mean range of particle size and uniformity coefficient for road runoff were $6.7{\sim}23.4{\mu}$ and $6.4{\sim}10.2$, respectively.
Skahill, Brian E.;Choi, Woo-Hee;Kim, Min-Hwan;Kim, Sung-Kyun;Johnson, Lynn E.
Journal of Korea Water Resources Association
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v.36
no.2
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pp.285-300
/
2003
An event-based, kinematic, infiltration-excess, and distributed rainfall-runoff model using weather radar and Geographic Information System(GIS) was developed to acknowledge and account lot the spatial variability and uncertainty of several parameters relevant to storm surface runoff and surface flow The developed model is compatible with raster GIS and spatially and temporally varied rainfall data. To calibrate the model, Monte Carlo simulation and a likelihood measure are utilized; allowing for a range of possible system responses from the calibrated model. Using rain gauge adjusted radar-rainfall estimates, the developed model was applied and evaluated to a limited number of historical events for the Ralston Creek and Goldsmith Gulch basins within the Denver Urban Drainage and Flood Control District (UDFCD) that contain mixed land use classifications. While based on a limited number of Monte Carlo simulations and considered flood events, Nash and Sutcliffe efficiency score ranges of -0.19∼0.95 / -0.75∼0.81 were obtained from the calibrated models for the Ralston Creek and Goldsmith Gulch basins, based on a comparison of observed and simulated hydrographs. For the Ralston Creek and Goldsmith Gulch basins, Nash and Sutcliffe efficiency scores of 0.88/0.10, 0.14/0.71, and 0.99/0.95 for runoff volume, peak discharge, and time to peak, respectively, were obtained from the model.
Hong, Sungjin;Lee, Chanwook;Park, Jiseung;Yoo, Do Guen
Journal of Korea Water Resources Association
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v.53
no.11
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pp.1015-1024
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2020
Recently, water pollution accidents have continued to occur in pipelines such as red water Incheon and Seoul. In order to recognize this water quality problem, it is necessary to install a water quality sensor in an appropriate location and measure it in advance to detect or block the water supply to the water faucet of the shelter. However, there are limitations, such as maintenance costs, to installing multiple water meters in all pipelines. Therefore, this study proposed a methodology for determining and prioritizing the installation location of flow-based water quality sensor for the recognition of water quality problems in pipelines. We applied the proposed procedure to the pipe break scenario. The results of the determination of the location of the water quality sensor were presented by applying it to the pipe network that actually operates the emergency pipe in Korea. The result of the decision showed that in the event of abnormal situation caused by the destruction of individual pipes, the flow rate of the pipes around the aqueduct and the tank may change rapidly, resulting in water quality accidents caused by turbidity. In the future, it is expected that the water quality monitoring point selection method, such as establishing an external pipe operation plan for pipe cleaning, will utilize the procedure for determining the location of the water quality sensor according to the velocity.
Using survey data of selected 1,349 individuals nationwide in Korea, we measure the influencing factors for the acceptance of nuclear power and estimates the probability of acceptance under several scenarios with different percentages of monetary compensation. Results of panel probit demonstrate that nuclear risk aversion tendency was found to be higher in case of female, younger age, past experience of extreme event such as an earthquake. However, the residents' residency nearby the nuclear power plant was not related to the risk-aversion tendency. In addition, we found that the nuclear acceptance is improved when the monetary compensation rate is increased. Although the policy demand intended to reduce GHG emissions in South Korea, the expansion of nuclear power is not be easy due to the occurrence of recent strong earthquakes because the risk attitude of an individual is influenced by subjective assessments formed through direct and indirect experiences of natural disasters such as an earthquake. Our results suggest that the opposition to construction of nuclear power plant is expected to be further intensified especially when combined with the experiences of threatening earthquakes. As a result, the debate and policy conflicts of nuclear power plants will consistently continue and large social costs are apparent for the acceptance of nuclear power plant.
PET images used in medical diagnoses are created using positron emitting radionuclides. The radiation used for imaging is generated at 0.511 MeV by p-annihilation. The CSDA range is the distance the particle radiation flew physically, and it is different from the range shown in PET images. This study proposes a novel method that uses radiological criteria to measure this range. The experiment was conducted by applying the MCNP6 simulation to positron emitting nuclides 18F, 11C, 13N, and 15O. Radiological criteria were based on the location of the p-annihilation event, which is also the image signal. Results showed the radiological range of positrons to be 2.3, 3.9, 5.0, and 7.9 mm for 18F, 11C, 13N, and 15O, respectively. The higher the positron energy, the larger its difference from the CSDA range. Positron emitting nuclide is being developed and studied as a nuclide for dosimetry or radiotherapy. Further research needs to be conducted into various positron ranges.
Kim, Ki Hyun;Seo, Kangmin;Cho, Hyun-Woo;Jeon, Jung-Hwan;Kim, Chan Ho;Jung, Jiyeon;Chun, Ju Lan
Journal of Animal Science and Technology
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v.63
no.6
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pp.1355-1361
/
2021
Digestibility of pet food can affect the health of dog, especially of aged animals. To maintain the health of dogs in an overall good status it is necessary to provide nutritionally balanced food. For example, the digestibility of dogs was known to be decreased along aging. In addition, losing teethes is an often event in aged dogs that could induce a problem to eat a large size dry pet food. Nonetheless, few detailed information is available on the most suited feeding for aged dogs. As part of the nutritional study of food for aged dogs, in this study, we tested whether food type impacts on digestibility on adult versus senior dogs. The methodology to measure the digestibility of nutrients was chosen the index method using chromium oxide. Dogs were fed the same commercial dry or wet diets, which were supplemented with 0.5% chromium oxide. The wet food was prepared by adding twice volume of water in the dry food prior to incubated overnight (14-16 hours) at room temperature. After five days, their feces were collected up to a total weight of > 200 g which was the amount to analyze undigested nutrients in feces as 3 repeats. In the apparent total tract digestibility analysis of the experimental breed, no difference in the digestibility of crude protein, crude fat, crude fiber, ash, and energy was observed regarding the moisture content of the food. Noteworthy, the digestibility of nitrogen free extract was significantly increased in senior dogs fed dry dog food compared with adult dogs fed the same diet, whereas no difference was observed between senior and adult dogs fed wet food. The small breed dogs showed similar results to the experimental breed dogs. However, the digestibility of crude fat was additionally affected by age and food type unlike the experimental breed dogs. This finding suggests that the food moisture content affects the digestibility of nutrients in dogs with aging. Hence, it may be helpful to determine the nutrient contents in foods for senior dogs depending on the food type.
Journal of the Korea Academia-Industrial cooperation Society
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v.20
no.9
/
pp.451-458
/
2019
Reliability in the course of weapons system development and operation is a key measure of the ability of a system to perform the required functions under specified conditions over a specified period of time, and the mission confidence for the assessment of mission fulfillment is an important indicator of victory or defeat in a battle. Mission reliability indicates the probability that a given task will succeed or fail in an event or environmental situation over a given period of time. The existing mission reliability was calculated after creating a confidence blow map with only physical connections based on the mission. However, as modern weapons systems evolve and advance, the related equipment structure becomes increasingly complex, making it impossible to express mission relevance when mission classification is required based on functional or physical connections. In this study, the mission reliability was calculated for a gun control system, which is part of a ship's combat system, by expressing the association between the physical and functional structures using the design structure matrix technique and the interface matrix technique. We expect the study results to be used as verification data for mission reliability.
The average annual rainfall in Busan to increase, and in case of Oncheon-Chen in Busan, frequent flooding occurred frequently. The middle and lower reaches of the Oncheon-Chen are relatively flat and urban areas are developed. Therefore, due to the frequent flooding of rivers and the large flood damage, a method of effectively eliminating the flow rate of Oncheon-Chen in the event of heavy rain is needed. In this study, underground waterway was established in the east of Hoedong-Reservoir as a measure to reduce floods in hot springs and simulated with EPA-SWMM. The information needed to construct the basin was utilized by GIS. In middle part of the Suyeong-Gang, there is a Hoedong-Reservoir and a dam is installed and has better conditions than the Nakdong-Gang. It also analyzed the effect of the Oncheon-Chen flow through the underground waterway on the Suyeong-Gang when it was transferred to the Hoedong-Reservoir. It was analyzed that the flood reduction rate at the flood risk points set up in this study was reduced by 24.64% on average when the underground waterway was installed, and the inflow of the water into the Suyeong-Gang increased by 1% on average when the flow rate was excluded by the Suyeong-Gang.
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