• Journal of Yeungnam Medical Science
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• v.34 no.2
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• pp.275-278
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• 2017

Small cell lung carcinoma (SCLC) is a cancer that shows aggressive behavior, early spread to distant sites, and frequent association with distinct paraneoplastic syndromes. Spontaneous remission of cancer, particularly of SCLC, is a rare biological event. Cases involving spontaneous regression of SCLC were reported, and were associated with paraneoplastic syndromes of the nervous system. This article reports on a 78-year-old man with SCLC in remission, with neurological symptoms. The patient visited the hospital because of generalized weakness, and imaging studies revealed a mass in the lower lobe of the left lung, pathological evaluation showed SCLC. The patient refused oncologic treatment and was treated only with conservative care. In follow-up study the diameter of the mass had decreased from initial 32 mm, 9 months after admission to 20 mm, 17 months after admission to 13 mm. The patient kept complaining of generalized weakness, dizziness, and paresthesia of limbs. We assumed that, in this case, the spontaneous remission of lung cancer was related to the immunologic response directed against the tumor, which is believed to be an important factor in the pathogenesis of paraneoplastic neurologic syndromes.

• Human Ecology Research
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• v.51 no.5
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• pp.551-561
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• 2013

The aim of this study was to develop and apply a list of meals and standard recipes using barley for diabetic patients. The degree of interest and requirements of diabetic patients were investigated for the development of meals. The ingredients of the meals were selected through the diabetic literature and previous research. While developing a list of meals, dietetic therapies for diabetic patients were considered. After developing 15 kinds of meals and modifying them through sensory evaluation, a standard recipe was completed. In the standard recipe, the menu name, the ingredients, quantity, and recipe were stated and the nutritional components were indicated. Photographs of the meals were included. The calorie prescription for the diabetic patients was aimed at elderly women, that is, those 65 years old or above, based on research showing this to be the average age of diabetics. The prescribed calories were 1,500 kcal based on the food exchange list. Weekly lists of meals including the developed dishes were made for diabetic patients. The list were modified after consultation with a clinical nutritionist. When completed, one meal item was selected for each day and cooked. A photograph was taken and presented diabetic patients. This article presents the standardized recipes of the developed list of meals and applies them to modifying the diabetic diet, with an aim to be of service to diabetic patients attempting to meet their dietetic therapy goals. We also provide basic data on institutional food services for diabetic patients and nutrition education.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.14 no.4
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• pp.1624-1647
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• 2020

Vehicular network is one of the most important subjects for researchers in recent years. Anycast routing protocols have many applications in vehicular ad hoc networks. The aim of an anycast protocol is sending packets to at least one of the receivers among candidate receivers. Studies done on anycast protocols over vehicular networks, however, have capability of implementation on some applications; they are partial, and application specific. No need to say that the lack of a comprehensive study, having a strong analytical background, is felt. Mathematical modeling in vehicular networks is difficult because the topology of these networks is dynamic. In this paper, it has been demonstrated that vehicular networks can be modeled based on time-expanded networks. The focus of this article is on geographical anycast. Three different scenarios were proposed including sending geographic anycast packet to exactly-one-destination, to at-least-one-destination, and to K-anycast destination, which can cover important applications of geographical anycast routing protocols. As the proposed model is of MILP type, a decentralized heuristic algorithm was presented. The evaluation process of this study includes the production of numerical results by Branch and Bound algorithm in general algebraic modeling system (GAMS) software and simulation of the proposed protocol in OMNET++ simulator. The comprehension of the result of proposed protocol and model shows that the applicability of this proposed protocol and its reactive conformity with the presented models based on presented metrics.

• Korean Journal of Oriental Medicine
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• v.13 no.2 s.20
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• pp.121-125
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• 2007

Background and Purpose : The purpose of this study was done to investigate what kinds of statistical techniques have been used to analyze data from oriental medicine research Methods : 135 original articles which used statistical techniques in their data analysis were selected from the articles published in The Journal of Korea Institute of Oriental Medicine(JKIOM) between 1995 to 2007. Results : Among 135 articles, 59 articles used descriptive statistics while 76 articles used inferential statistics for data analysis. For that 76 articles, two-sample t-test(33 articles), analysis of variance(29 articles), regression(9 articles), chi-square test(5 articles), nonparametic test(4 articles), Fisher's exact test(3 articles), and other test(9 articles) were chosen to analyze the data. SAS and SPSS statistical softwares(82.50%) were mostly used to analyze the data. Nonparametic tests were used to 4 articles(6.97%) of 67 articles and parametic tests were used to 63 articles(93.03%) of 67 articles. Among 29 articles used analysis of variance, duncan(8 articles), dunnet(4 articles), bonferroni(4 articles), turkey(3 articles), scheff(1 article) were used to do multiple comparison. 9 articles did not carry out the multiple comparison. Conclusions : It was found that the frequencies of statistical package used and statistical analysis used were not much by now. High level statistical analyses were not used most for oriental medicine research.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.44 no.4
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• pp.12-22
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• 2021

This article suggests the machine learning model, i.e., classifier, for predicting the production quality of free-machining 303-series stainless steel(STS303) small rolling wire rods according to the operating condition of the manufacturing process. For the development of the classifier, manufacturing data for 37 operating variables were collected from the manufacturing execution system(MES) of Company S, and the 12 types of derived variables were generated based on literature review and interviews with field experts. This research was performed with data preprocessing, exploratory data analysis, feature selection, machine learning modeling, and the evaluation of alternative models. In the preprocessing stage, missing values and outliers are removed, and oversampling using SMOTE(Synthetic oversampling technique) to resolve data imbalance. Features are selected by variable importance of LASSO(Least absolute shrinkage and selection operator) regression, extreme gradient boosting(XGBoost), and random forest models. Finally, logistic regression, support vector machine(SVM), random forest, and XGBoost are developed as a classifier to predict the adequate or defective products with new operating conditions. The optimal hyper-parameters for each model are investigated by the grid search and random search methods based on k-fold cross-validation. As a result of the experiment, XGBoost showed relatively high predictive performance compared to other models with an accuracy of 0.9929, specificity of 0.9372, F₁-score of 0.9963, and logarithmic loss of 0.0209. The classifier developed in this study is expected to improve productivity by enabling effective management of the manufacturing process for the STS303 small rolling wire rods.

• Journal of Trauma and Injury
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• v.22 no.2
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• pp.248-253
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• 2009

Purpose: Hemodynamically unstable pelvic fractures represent therapeutic challenges for the trauma team. The authors of this article have studied the clinical profiles of the angiographic intervention population at the emergency department during four years (2005~2009) to develop clinical guidelines for preventing deaths due to multiple trauma and for predicting the prognosis during initial evaluation. Methods: We performed a retrospective review of 34 patients who had undergone angiographic interventions at the emergency department and compared the differences in clinical variables between survivors and non-survivors. Results: Representative values were compared between survivors and non-survivors : RTS (revised trauma score) 7.006 (6.376~7.841) vs. 6.128 (4.298~6.494), PRC (packed red cell) units 5.5 (2.0~11.0) vs. 15 (8.0~18.5), and lactate (mmol/L) 3.0 (1.0~7.0) vs. 8.5 (3.5~10.5). RTS (p<0.01) and PRC units before angiographic interventions (p=0.01) and lactate (p=0.02) had correlations to the final outcomes. Conclusion: The availability of an angiographic suite and persistent hypotension after adequate fluid resuscitation for pelvic trauma are good indications of angiographic intervention for pelvic hemorrhage.

• Bulletin of the Korean Chemical Society
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• v.26 no.5
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• pp.740-746
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• 2005

In this article, we report the tandem mass spectrometry investigations for the electron capture efficiencies of the protons belonging to the different locations (generations) in a poly(propylene imine) dendrimer with three layers of a repeat unit (named as the third generation dendrimer). The employed tandem mass spectrometry methods include SORI-CAD (sustained off-resonance irradiation collisional activation dissociation) and ECD(electron capture dissociation) mass spectrometry. We obtained SORI-CAD spectra for the dendrimer ions in the different charge states, ranging from 2+ to 4+. The analysis of fragmentation sites provides the information as to where the protons are distributed among various generations of the dendrimer. Based upon this, a new strategy to study the electron capture efficiencies of the protons is utilized to examine a new type of triplycharged ions by SORI-CAD, i.e., the 3+ ions generated from the charge reduction of the native 4+ ions by ECD: (M+4H)$^{4+}\;+\;e^-\;{\rightarrow}$ (M+4H)$^{3+\bullet}$ ${\rightarrow}\;({H^{\bullet}}_{ejected}$) + (M+3H)$^{3+}\;\rightarrow$ CAD. Interestingly, comparison of these four SORICAD spectra indicates that the proton distribution in the charge-reduced 3+ ions is very close to that in the native 4+ ions. It further suggests that in this synthetic polymer ($\sim$1.7 kDa) with an artificial architecture, the electron capture efficiencies of the protons are actually insensitive to where they are located in the molecule. This is somewhat contradictory to common expectations that the protons in the inner generations may not be well exposed to the incoming electron irradiation as much as the outer ones are, thus may be less efficient for electron capture. This finding may carry some implications for the case of medium sized peptide ions with similar masses, which are known to show no obvious site-specific fragmentations in ECD MS.

• Korean Journal of Food Science and Technology
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• v.44 no.2
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• pp.168-172
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• 2012

This article presents an evaluation of the effects of coating conditions on the enteric coating quality of soft gelatin capsules containing Omega-3 fatty acids. Three conditions were controlled: concentration of hydroxypropyl methylcellulose phthalate (6, 8, and 10 wt% in solution), temperature of the inlet air (32, 35, and $38^{\circ}C$), and the coating solution feed rate (7.5, 11.25, and 15.0 g/min). The transparency of the enteric coated soft gelatin capsules was evaluated by measuring the degree of whiteness of the surface using a spectrophotometer. Results showed that the most important parameter in the enteric coating process was the coating solution feed rate. As the coating solution feed rate decreased and inlet air temperature increased, the degree of whiteness of coating surfaces decreased. We also evaluated the disintegration properties of the enteric coated capsules in accordance with the Korea Health Functional Food Code.

• Journal of the Korean housing association
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• v.26 no.6
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• pp.35-42
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• 2015

The Brazilian Federal Housing Program "Minha Casa Minha Vida" -PMCMV (My House My Life) is part of a large housing policy to eradicate the housing deficit, estimated at around five million homes in the country. The Ministry for Cities created a network of independent research organizations to evaluate the program, and the PMCMV has attracted many studies. Despite the inherent worth of these individual studies, there is a need for a holistic evaluation. A Systematic Literature Review (SLR) is seen as an important contribution to focus research efforts on the problems identified, to avoid the repetition of studies and to provide novel insights. This article carried out a SLR to map and quantify the types of research and represent a graphic panorama of published studies. Gap spotting was part of the study. In the five-year period from 2010-2014, the SLR identified 1489 bibliographic items. The panorama is categorised according to types of publications, and the analysis of items shows that most studies are concentrated on housing policies, financial questions, urban impacts and Brazilian social development. The results of this SLR raise some new research questions and show opportunities to reduce errors in the housing projects themselves.

• Smart Structures and Systems
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• v.26 no.3
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• pp.391-401
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• 2020

The present article reports the feasibility of the electrical energy generation from ambient low-frequency vibration using a piezoelectric material mounted on a bimorph cantilever beam actuator. A corresponding higher-order analytical model is developed using MATLAB in conjunction with finite element method under low-frequency with both damped and undamped conditions. An alternate model is also developed to check the material and dimensional viability of both piezoelectric materials (mainly focussed to PVDF and PZT) and the base material. Also, Genetic Algorithm is implemented to find the optimum dimensions which can produce the higher values of voltage at low-frequency frequencies (≤ 100 Hz). The delamination constraints are employed to avoid inter-laminar stresses and to increase the fracture toughness. The delamination has been done using a Teflon sheet sandwiched in between base plates and the piezo material is stuck to the base plate using adhesives. The analytical model is tested for both homogenous and isotropic material characteristics of the base material and extended to investigate the effect of the different geometrical parameters (base plate dimensions, piezo layer dimensions and placement, delamination thickness and placement, excitation frequency) on the model responses of the bimorph cantilever beam. It has been observed that when the base material characteristics are homogenous, the efficiency of the model remains higher when compared to the condition when it is of isotropic material. The necessary convergence behaviour of the current numerical model has been established and checked for the accuracy by comparing with available published results. Finally, using the results obtained from the model, a prototype is fabricated for the experimental validation via a suitable circuit considering Glass fibre and Aluminium as the bimorph material.