• Title/Summary/Keyword: Euporia longana

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5-(Hydroxymethyl)-2-furfuraldehyde, Anticonvulsant Furan from the Arils of Euphoria longana L.

  • Kim, Dong-Hyun;Kim, Dae-Won;Choi, Soo-Young;Park, Chang-Ho;Baek, Nam-In
    • Journal of Applied Biological Chemistry
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    • v.48 no.1
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    • pp.32-34
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    • 2005
  • Arils of Euporia longana L. was extracted with 80% aqueous MeOH and partitioned successively with EtOAc, n-BuOH and $H_2O$. From the n-BuOH fraction, furan compound was isolated through silica gel column chromatography. The results of physico-chemical data including NMR, MS and IR revealed the compound to be 5-(hydroxymethyl)-2-furfuraldehyde. This compound stimulated GDH I activity by $19.2{\pm}0.6$, $41.2{\pm}0.9$, $68.4{\pm}1.1$, $80.3{\pm}0.9$ and $85.9{\pm}1.6%$ at in vitro concentrations of 0.005, 0.008, 0.02 and 0.03 %, respectively.