• 제목/요약/키워드: Euphorbia

검색결과 128건 처리시간 0.027초

HaCaT 각질형성세포에서 홍조류인 단박(Ceramium boydenii)의 STAT1 활성 억제를 통한 MDC/CCL22 생성 억제 효과 (Ceramium boydenii, a Red Alga, Inhibits MDC/CCL22 Production Via Suppression of STAT1 Activation in HaCaT Keratinocyte)

  • 강나진;강경진;한상철;현은아;구동환;고영상;고미희;현진원;강희경;유은숙
    • 생약학회지
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    • 제44권2호
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    • pp.154-160
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    • 2013
  • Ceramium boydenii belongs to euphorbia humitusa of red algae, and is distributed along the coast of Jeju island. This study was conducted to examine the anti-inflammatory effect and action mechanism of C. boydenii in the human keratinocyte cell line HaCaT. The 80% EtOH extract of C. boydenii inhibits the production of MDC (macrophage derived chemokine), an inflammatory chemokine, induced by IFN-${\gamma}$ and TNF-${\alpha}$ in a concentration dependent manner. It also suppressed the phosphorylation and nuclear translocation of STAT1, a key transcription factor in IFN-${\gamma}$ and TNF-${\alpha}$ signaling pathway, at the effective concentrations. These results suggest that C. boydenii demonstrates the anti-inflammatory activity via the suppression of STAT1 activation and has the significant value as an anti-inflammatory source.

Characterization of a Strain of Malva Vein Clearing Virus in Alcea rosea via Deep Sequencing

  • Wang, Defu;Cui, Liyan;Pei, Yanni;Ma, Zhennan;Shen, Shaofei;Long, Dandan;Li, Lingyu;Niu, Yanbing
    • The Plant Pathology Journal
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    • 제36권5호
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    • pp.468-475
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    • 2020
  • Malva vein clearing virus (MVCV) is a member of the Potyvirus species, and has a negative impact on the aesthetic development of Alcea rosea. It was first reported in Germany in 1957, but its complete genome sequence data are still scarce. In the present work, A. rosea leaves with vein-clearing and mosaic symptoms were sampled and analyzed with small RNA deep sequencing. By denovo assembly the raw sequences of virus-derived small interfering RNAs (vsiRs) and whole genome amplification of malva vein cleaning virus SX strain (MVCV-SX) by specific primers targeting identified contig gaps, the full-length genome sequences (9,645 nucleotides) of MVCV-SX were characterized, constituting of an open reading frame that is long enough to encode 3,096 amino acids. Phylogenetic analysis showed that MVCV-SX was clustered with euphorbia ringspot virus and yam mosaic virus. Further analyses of the vsiR profiles revealed that the most abundant MVCV-vsiRs were between 21 and 22 nucleotides in length and a strong bias was found for "A" and "U" at the 5′-terminal residue. The results of polarity assessment indicated that the amount of sense strand was almost equal to that of the antisense strand in MVCV-vsiRs, and the main hot-spot region in MVCV-SX genome was found at cylindrical inclusion. In conclusion, our findings could provide new insights into the RNA silencing-mediated host defence mechanism in A. rosea infected with MVCV-SX, and offer a basis for the prevention and treatment of this virus disease.

북경남 변전소 사업부지의 관속식물 현황과 분포 (Distribution and Status of Vascular Plants a Site of Project in the Bukkvungnam Substation)

  • 오현경;김철환
    • 한국환경복원기술학회지
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    • 제11권2호
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    • pp.66-74
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    • 2008
  • In recent years, the view centered conservation for eco-system is getting important rather than development from human oriented perspective. As a result, the concept "Sustainable development", that is seeking harmony between conservation and development, appeared so that we researched distribution and status of vascular plants a site of project in the Bukkyungnam substation. The main findings from the study is as follows. The vascular plants a site of project in the Bukkyungnam substation area was listed 435 taxa; 93 families, 269 genera, 377 species, 1 subspecies, 51 varieties and 6 forms. Specific plant species by floral region were total 25 taxa; Acer palmatum (Planted species), Asperula lasiantha in Class III, Caryopteris incana, Cirsium schantarense in Class II, 21 taxa (Dryopteris erythrosora, Chloranthus japonicus, Salix glandulosa, Alnus hirsuta, Quercus variabilis, Ulmus parvifolia, Clematis patens, Rubus hirsutus, Euphorbia pekinensis, Cayratia japonica, Grewia biloba var. parviflora, Vaccinium oldhami, Microstegium japonicum, Hosta capitata, Polygonatum falcatum, etc.) in Class I. Based on the list of Korean endemic plants, 10 taxa were recorded; Cephalotaxus koreana, Populus tomentiglandulosa (Planted species), Indigofera koreana, Forsythia koreana (Planted species), Paulownia coreana (Planted species), Asperula lasiantha, Weigela subsessilis, Adenophora triphylla var. hirsuta, Carex okamotoi, Lilium amabile and based on the list of the rare plants by the Forest ResearchInstitute, 2 taxa were recorded in the studied areas; Lilium callosum (Preservation priority order; No. 191), Aristolochia contorta (No. 151). The naturalized plants in this site were 13 families, 22 genera, 28 taxa and naturalization rate was 6.4% of all 435 taxa vascular plants.

전주 학산 일대의 관속식물 분포특성 및 관리방안 (Distribution Characteristics and Management Counterplan of Vascular Plants in the Haksan (Mt.), Jeonju)

  • 변무섭;오현경;한윤희
    • 한국환경복원기술학회지
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    • 제13권1호
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    • pp.14-23
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    • 2010
  • The vascular plants in the Haksan, Jeonju were listed 394 taxa; 94 families, 260 genera, 339 species, 1 subspecies, 46 varieties and 8 forms. Divided into woody plants were 111 taxa (28.2%) and herbaceous plants were 283 taxa (71.8%). Based on the list of rare plants by the Korea Forest Service; Viola albida (Preservation priority order : No. 202), Korean endemic plants, 6 taxa were recorded; Lespedeza maximowiczii for. tomentella, Indigofera koreana, Weigela subsessilis, etc. Specific plant species by floral region were total 19 taxa (4.8% of all 394 taxa of vascular plants); Wistaria floribunda (Planted species) in class IV, Acer palmatum (Planted species) and Melothrua japonica in class III, Nymphoides indica in class II, 15 taxa (Botrychium virginianum, Hosta capitata, Salix glandulosa, Quercus variabilis, Rhynchosia acuminatifolia, Ilex macropoda, Impatiens nolitangere, Grewia biloba var. parviflora, Vaccinium oldhami and Lonicera praeflorens, etc.) in class I. The naturalized plants in the surveyed sites were 14 families, 30 genera, 32 taxa (Bromus rigidus, Rumex obtusifolius, Chenopodium ficifloium, Amaranthus lividus, Phytolacca americana, Lepidium apetalum, Amorpha fruticosa, Geranium carolinianum, Ailanthus altissima, Euphorbia supina, Oenothera biennis, Ipomoea purpurea, Veronica persica, Bidens frondosa, etc.) and naturalization rate was 8.1% of all 394 taxa of vascular plants. The ecosystem disturbing wild plants, Rumex acetocella, Aster pilosus and Ambrosia artemisiaefolia having manage to designation with Ministry of Environment.

Candidiosis 치료제 개발을 위한 약용 및 야생 식물의 항진균 활성의 검색 (Screening of anti-candidiosis agent from medicinal and wild plants)

  • 손호용;금은주;권윤숙;권기석;진익렬;권하영;권정숙;손건호
    • 생명과학회지
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    • 제13권5호
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    • pp.604-617
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    • 2003
  • 안전성이 확보된 식용, 또는 약용식물로부터 항캔디다 활성이 우수한 항진균 후보물질을 개발하기 위해, 298종의 천연물로부터 추출부위 및 추출 용매를 달리하여 384종의 추출물을 제조하였다. 제조된 추출물의 항캔디다 활성을 disc-paper를 이용한 생육 저지환의 유무 및 크기 판정과 microbroth dilution법을 이용하여 C. albicans KCTC 1940과 S. cerevisiae IFO 0233를 대상으로 평가하였다. 그 결과 20종 식물로부터 조제된 25종의 추출물이 우수한 항캔디다 활성을 나타냄을 확인하였고, 그 중에서도 멍석딸기, 정향, 천황련, 작약, 모란, 대극잎 추출물은 강력 한 항캔디다 활성$(MIC=50 \mug/m\ell)$을 보였다. 특히, 멍석딸기(에틸아세테이트 추출물), 정향(부탄올 추출물), 호장근(에틸아세테이트 추출물), 작약(부탄올 추출물), 대극잎(메탄올 추출물)의 경우에는 C. albicans에 높은 선택독성을 나타내어, 안정성이 확보된 식물 추출물로부터 새로운 진균 감염증 치료제 개발이 가능함을 제시하였다.

박동관류 심방모델에서 강심효과를 나타내는 단미 한약재 검색 (Screening of Positive Inotropic Effect from Herbal Extracts in Beating Rabbit Atria)

  • 이윤정;권오정;김혜윰;남궁승;이재윤;유윤조;강대길
    • 동의생리병리학회지
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    • 제30권1호
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    • pp.40-46
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    • 2016
  • Many medicinal plants have been used for the treatment of edema, jaundice, and gonorrhea in traditional Oriental medicine. This screening study was designed to search the positive inotropic effects of herbal extracts in beating rabbit atria. Aquarius extracts of twenty six herbs were examined in atrial mechanical dynamics such as pulse pressure and stroke volume and atrial natriuretic peptide (ANP), one of the main hormones involved in the regulation of the body fluid and blood pressure homeostasis in perfused beating rabbit atria. Sophora flavescens Ait., Rheum officinale Baill., Acorus gramineus Sol., Chelidonium majus L., Pulsatilla koreana Nakai., Reynoutria japonica Houtt., Euphorbia lathyris L., Pyrrosia lingua (Thunb.) Farwell, Poncirus trifoliata Rafin., Anemarrhena asphodeloides Bunge, Kochia scoparia Schrad. significantly increased stroke volume and pulse pressure. However, those herbal extracts were not induced ANP secretion. We clarified the eleven herbal extracts for the positive inotropic effect independent of ANP secretion in beating rabbit atria. Thus these results provide a beneficial data for the treatment of the impairment of body fluid and blood pressure in traditional Oriental medicine.

Assessment of β-Lactamase Inhibitor Potential of Medicinal Plant Extracts against Antibiotic-resistant Staphylococcus aureus

  • Dawan, Jirapat;Ahn, Juhee
    • 한국자원식물학회지
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    • 제33권6호
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    • pp.578-585
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    • 2020
  • This study was designed to assess the possibility of using medicinal plant extracts as β-lactamase inhibitors to control antibiotic-resistant Staphylococcus aureus. The susceptibilities of S. aureus ATCC 15564 (SAWT), ciprofloxacininduced S. aureus ATCC 15564 (SACIP), oxacillin-induced S. aureus ATCC 15564 (SAOXA), and clinically-isolated S. aureus CCARM 3008 (SACLI) to ampicillin were determined in the absence and presence of medicinal plant extracts, including Cleyera japonica (CJ), Carpinus laxiflora (CL), Euphorbia helioscopia (EH), Euscaphis japonica (EJ), Oenothera erythrosepala (OE), and Rosa multiflora (RM). The phenotypic change in the clear inhibition zones around ampicillin disc was observed for SAWT, SACIP, and SAOXA, indicating the production of ampicillinase. Compared to the controls, the MICs of ampicillin against SAWT, SACIP, and SAOXA were decreased from 4 to 0.5 ㎍/mL in the presence of CL, 16 to 4 ㎍/mL in the presence of RM, and 32 to 2 ㎍/mL in the presence of CL, EH, and RM, respectively. The medicinal plant extracts, OE, EJ, and CL, effectively inhibited the β-lactamase activities of SAWT (78%), SACIP (57%), and SAOXA (76%) when compared to the control. This results suggest that the medicinal plant extracts can be used as BLIs to control the antibiotic-resistant S. aureus.

담배가루이 Bemisia tabaci(Gennadius)(Homoptera: Aleyrodidae)의 형태적 특징과 DNA 표식자에 의한 biotype 판별 (Morphological Characteristics of Bemisia tabaci(Gennadius) (Homoptera: Aleyrodidae) and Discrimination of Their Biotypes in Korea by DNA Makers)

  • 이명렬;안성복;조왕수
    • 한국응용곤충학회지
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    • 제39권1호
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    • pp.5-12
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    • 2000
  • 임의증폭 다형 DNA(RAPD)와 미토콘드리아 12S, 16S rRNA 유전자의 제한단편 DNA 표식자에 의해 한국에서 발생하는 담배가루이 개체군들의 biotype을 판별하였다. 진천의 장미 온실과 서울 내곡동의 포인세티아 온실에서 발생한 담배가루이는 일본, 이스라엘, 호주의 B biotype 과 동일한 DNA 단편들을 보유하였다. 여러 지역의 노지 콩 (Glycine max), 고구마 (Ipomea batatas), 들깨 (Perilla frutescens)에서 채집된 담배가루이 개체군들은 일본 시코쿠의 인동덩굴(Lonicera japonica)에서 채집된 담배가루이와 같은 DNA로 표식되었다. 이들 non-B biotype은 한국, 일본 등 극동아시아 지역에 고유한 계통으로 보인다. 최근 한국에서 발견된 담배가루이 Bemisia tabaci(Gennadius)의 주사전자현미경 관찰에 의한 형태적 특정을 온실 원예작물의 주요해충인 온실가루이 Trialeurodes vaporariorum (Westwood)와 비교하여 기재하였다.

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적색의 컴팩트한 포인세티아 'Clara' (Breeding of Red Compact Poinsettia Cultivar 'Clara')

  • 이은경;김원희;김성태;이수영
    • 한국육종학회지
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    • 제42권6호
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    • pp.664-667
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    • 2010
  • 'Clara' 품종은 국립원예특작과학원에서 2005년도에 육성한 포인세티아 품종이다. 이 품종은 2002년에 진한 녹색 잎에 엽절이 있으며 선명한 적색인 'Red Velvet'을 모본으로, 단일반응이 빠르고 밝은 적색인 'Freedom Bright Red'를 부본으로 인공교배하여 양성된 실생계통 중 선발되었다. 2003년, 2004년 2차에 거쳐 특성검정을 하여 '원교 D5-12'를 육성하였고 2005년에 3차 특성검정과 품평회를 실시하여 최종선발 하였으며, 농작물 직무육성 신품종선정위원회를 거쳐 'Clara'로 명명하였다. 포엽의 형태는 난형이며 포엽의 엽맥 사이에 약한 주름이 있고 포엽의 색상은 적색이다. 잎몸은 난형이며 중간 녹색이고 엽절이 거의 없으며 엽병이 짧다. 줄기 색은 적색계이며 적심을 하지 않은 상태에서도 분지가 발생하고 줄기의 수는 중간이다. 초장은 작고 컴팩트한 수형을 이루며 단일처리 후 약 9주일이 경과하면 완전히 착색되어 출하가 가능하다.

밝은 황록색 포인세티아 'Green Dream' (Breeding of Light Yellow-Green Poinsettia 'Green Dream')

  • 이은경;김원희;김성태;이광식;이수영
    • 한국육종학회지
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    • 제43권6호
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    • pp.568-571
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    • 2011
  • 'Green Dream' 품종은 국립원예특작과학원에서 2009년도에 육성한 포인세티아 품종이다. 이 품종은 2006년에 진한 녹색잎에 초장이 짧고 아담한 연황색의 'Lemon Snow'를 모본으로, 생육이 왕성하고 진한 분홍색인 'Freedom Rose'를 부본으로 인공 교배하여 양성된 실생계통이다. 2007년과 2008년 2차에 거쳐 특성검정을 하여 '원교 D5-64'를 육성하였고 2009년에 3차 특성검정과 품평회를 실시하여 최종선발 하였으며, 농작물 직무육성 신품종선정위원회를 거쳐 '그린드림 (Green Dream)'으로 명명하였다. 포엽의 형태는 난형이며 포엽의 엽맥 사이에 중간 정도의 주름이 있고 포엽의 색상은 밝고 연한 황록색이다. 잎몸은 난형이며 진한 녹색이고 엽절이 적으며 엽병이 길다. 줄기 색은 녹색계이며 적심을 하지 않은 상태에서도 분지가 발생하고 줄기의 수는 중간이다. 초장은 크며 단일처리 후 약 7주일이 경과하면 완전히 착색되어 출하가 가능하다.