• Journal of Oriental Neuropsychiatry
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• v.8 no.1
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• pp.183-200
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• 1997

I got the following result from the bibliographic study about the meaning of Hwa(火) and Hwa- byung(火病) at the concept and the aspect of pathological and etiological factors.The results are as follows.1. The pathological characteristics of Hwa(火) mean the inflammed state, the excited mental condition and perinervous hyperfunction caused by exopathy produced by any of the six extermal etiological factors(外感六淫) and Hwa caused by interior injury(內傷火熱).2. Hwa caused by the fire emotions(五志之火); anger, gladness, contemplation, sadress, fear by menta complications brings to Hwa caused by the five viscera(五臟之火) and Hwa caused by the stagnation of the liver - energy(肝鬱之火) is the rpresentive Hwa caused by the five viscera and the six hollow organs(贓腑之火).3. A symptom caused by a pathogenic Hwa(火證) is understood in a pathological sense involved an inflammed disease and is considered as a pathological state of excess syndrome(實證) caused by exterior Hwa( 外火).4. The pathologic process of Hwa-byung(火病) as the mental disease is based upon our people's emotion; Han(恨) to be pathologized without being overcome and can be considered as the process of Hwa caused by long-term(鬱久而火化).5. Hwa-byung(火病) means a psychosomatic disorder resulting from stress reaction caused by personal relations in the climacterium.Form the above mentioned study, the meaning of Hwa(火) and Hwa-byung(火病) is set theoretically and it also needs to be maintained reserching and studying about Hwa-byung(火病) consistantly.

• Clinical and Experimental Pediatrics
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• v.63 no.11
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• pp.447-450
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• 2020

Background: Esophageal stricture (ES) is an uncommon clinic entity in pediatrics that may be congenital or acquired in childhood. Acquired noncaustic ES is very rare, and clinical features of affected patients are unknown. Purpose: We aimed to evaluate the clinical findings, and outcomes of patients with acquired noncaustic ES to aid physicians in the early referral of patients to gastroenterologists. Methods: The medical data of patients with acquired noncaustic ES who were followed in our gastroenterology clinic between January 2009 and December 2019 were reviewed. Results: Acquired noncaustic ES was found in 12 of the 4,950 patients (0.24%) who underwent endoscopy during the study period. The main symptoms were dysphagia (58.3%), vomiting (33.3%), and chronic anemia (8.3%). Chronic malnutrition and underweight were found in 66.6% of the patients. The most common etiological factors were radiotherapy, peptic reflux, and achalasia (16.6%, each), while chemotherapy, squamous-cell carcinoma (SC) of the esophagus, eosinophilic esophagitis (EoE), esophageal web, epidermolysis bullosa, and esophageal diverticulum (8.2%, each) were the other etiological factors. Patients with EoE underwent endoscopic bougie dilation in addition to steroid use and elimination diet. Patients with epidermolysis bullosa and esophageal web underwent bougie dilation. Patients with peptic reflux-related ES were initially put on antireflux therapy, but during follow-up, one patient required esophageal replacement with colonic interposition. Patients with radiotherapy-related ES recovered with medical therapy. The patient with initially underwent surgical gastrostomy and tumoral mass excision. The patient then received chemotherapy and radiotherapy and underwent jejunal interposition. Patients with achalasia underwent surgical esophagomyotomy. Conclusion: The presence of solid dysphagia, malnutrition, and an associated disease may alert physicians to the presence of ES.

• Journal of Biomedical and Translational Research
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• v.19 no.4
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• pp.110-115
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• 2018

Transient ischemic attack (TIA) indicates high risk for major stroke and is considered a medical emergency. Diffusion-weighted imaging (DWI) enables detection of acute ischemic lesions. The clinical significance of DWI positive lesions in TIA is obscure and its prevalence, clinical features are not established. Therefore, we performed a clinical, etiological and prognostic analysis through a cross-sectional analysis of 235 TIA patients, grouped according to presence of DWI lesion. Clinical features, underlying risk factors for stroke, outcome and rate of recurrence were analyzed. 3 months follow-up of modified Rankin Scales (mRS) were done with telephone survey. DWI positive lesions were present in 14.0% of patients. Etiological factors significantly associated with DWI lesions in TIA patients were male sex (p = 0.038), stroke history (p = 0.012) and atrial fibrillation (p < 0.001). Presence of at least one medium or high risk of cardioembolism from TOAST classification were not associated with lesions when excluding association to atrial fibrillation (p = 0.108). Clinical features showed no significant difference. Whether the patients had lesion-positive DWI was not related to an increase in mRS score during the hospital stay or at the 3-month follow-up after discharge. Future studies should include multi-center samples with large numbers, considering each unique medical environment. Routine acquisition of follow-up DWI for proper evaluation of the tissue-based definition of TIA should also be considered.

• Journal of Korean Neurosurgical Society
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• v.56 no.1
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• pp.21-27
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• 2014

Objective : Infectious spinal disease is regarded as an infection by a specific organism that affects the vertebral body, intervertebral disc and adjacent perivertebral soft tissue. Its incidence seems to be increasing as a result of larger proportion of the older patients with chronic debilitating disease, the rise of intravenous drug abuser, and the increase in spinal procedure and surgery. In Korea, studies assessing infectious spinal disease are rare and have not been addressed in recent times. The objectives of this study are to describe the epidemiology of all kind of spinal infectious disease and their clinical and microbiological characteristics as well as to assess the diagnostic methodology and the parameters related to the outcomes. Methods : A retrospective study was performed in all infectious spinal disease cases presenting from January 2005 to April 2010 to three tertiary teaching hospitals within a city of 1.5 million in Korea. Patient demographics, risk factors, clinical features, and outcomes were assessed. Risk factors entailed the presence of diabetes, chronic renal failure, liver cirrhosis, immunosuppressants, remote infection, underlying malignancy and previous spinal surgery or procedure. We comparatively analyzed the results between the groups of pyogenic and tuberculous spinal infection. SPSS version 14 statistical software was used to perform the analyses of the data. The threshold for statistical significance was established at p<0.05. Results : Ninety-two cases fulfilled the inclusion criteria and were reviewed. Overall, patients of tuberculous spinal infection (TSI) and pyogenic spinal infection (PSI) entailed 20 (21.7%) and 72 (78.3%) cases, respectively. A previous spinal surgery or procedure was the most commonly noted risk factor (39.1%), followed by diabetes (15.2%). The occurrence of both pyogenic and tuberculous spondylitis was predominant in the lumbar spine. Discs are more easily invaded in PSI. At initial presentation, white cell blood count and C-reactive protein levels were higher in PSI compared to TSI (p<0.05). Etiological agents were identified in 53.3%, and the most effective method for identification of etiological agents was tissue culture (50.0%). Staphyococcus aureus was the most commonly isolated infective agent associated with pyogenic spondylitis, followed by E. coli. Surgical treatment was performed in 31.5% of pyogenic spondylitis and in 35.0% of tuberculous spondylitis cases. Conclusion : Many previous studies in Korea usually reported that tuberculous spondylitis is the predominant infection. However, in our study, the number of pyogenic infection was 3 times greater than that of tuberculous spinal disease. Etiological agents were identified in a half of all infectious spinal disease. For better outcomes, we should try to identify the causative microorganism before antibiotic therapy and make every effort to improve the result of culture and biopsy.

• Safety and Health at Work
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• v.2 no.1
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• pp.1-8
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• 2011

The knowledge on the etiology of breast cancer has advanced substantially in recent years, and several etiological factors are now firmly established. However, very few new discoveries have been made in relation to occupational risk factors. The International Agency for Research on Cancer has evaluated over 900 different exposures or agents to-date to determine whether they are carcinogenic to humans. These evaluations are published as a series of Monographs (www.iarc.fr). For breast cancer the following substances have been classified as "carcinogenic to humans" (Group 1): alcoholic beverages, exposure to diethylstilbestrol, estrogen-progestogen contraceptives, estrogen-progestogen hormone replacement therapy and exposure to X-radiation and gamma-radiation (in special populations such as atomic bomb survivors, medical patients, and in-utero exposure). Ethylene oxide is also classified as a Group 1 carcinogen, although the evidence for carcinogenicity in epidemiologic studies, and specifically for the human breast, is limited. The classification "probably carcinogenic to humans" (Group 2A) includes estrogen hormone replacement therapy, tobacco smoking, and shift work involving circadian disruption, including work as a flight attendant. If the association between shift work and breast cancer, the most common female cancer, is confirmed, shift work could become the leading cause of occupational cancer in women.

• The Journal of Korean Medicine
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• v.16 no.1 s.29
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• pp.118-131
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• 1995

According to the oriental medicine study on G.B.S, we obtained the result as follows : 1. G.B.S was inclined in flacid paralysis and pain and numbness(痺) in oriental medicine. 2. Etiology factors of G.B.S was classified exogenous and endogenous pathogenic factors. The formers was warmth and heat(濕熱), summer heat and dampness(暑濕), dampness and heat(濕熱), and cool and dampness(寒濕), the latter was the deficiency in both the spleen and the stomach(脾胃虛弱), deficiency of Yin(vital essence) in both the liver and kidney(肝腎陰虛) the factor of dampness and heat(濕熱) was most numerous. 3. Pathological mechanism of G.B.S was close connected with the five viscera - the spleen(脾), the stomach(胃), the liver(肝), the kidney(腎), the lung(肺) 4. Differentiation of Symptom-Complexes(辨症) in the G.B.S was consumption type of nutrient fluid due to heat symptom in the lung(肺熱傷津), fullness type of dampness and heat(濕熱侵淫), defiency type in both the spleen and the kidney(脾腎不足), deficiency type in both the spleen and the stomach(脾胃虛弱), deficiency type in the liver and the kidney(肝腎兩虛) 5. Acupuncture treatment for G.B.S was mainly Yangmoung channels of both the hand and the foot.(手足陽明經)

• The Journal of Internal Korean Medicine
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• v.21 no.5
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• pp.739-745
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• 2000

xWe studied about the causes of hypertension in the occidental and oriental medical records and the results are as follows. 1. The causes of hypertension in oriental medicine can be divided into wind, fire, phlegm and deficiency of Qi in our body, and broadly into three categories as emotions in excess, improper diet and damages of endogenous etiological factors. 2. Hypertension is the disease of undermining of fundamental aspects while prevailing incidental aspects and liver, heart and kidneys are the organs mainly related to hypertension. 3. The main pathological factors of hypertension are as follows; the disorder of Yin and Yang makes the situation of the deficiency of the vital essence of kidneys and the exuberance of the vital essence of liver and they are the fundamentals to be taken hypertension and finally make the state of the deficiency of both Yin and Yang. 4. In the point of occidental medical view, the essential hypertension is a disease of unknown etiology and we think it occurs not on the only one factor but on the various factors and secondary hypertension occurs from the diseases of the substances and the vessels of kidneys.

• Journal of Haehwa Medicine
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• v.15 no.1
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• pp.59-69
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• 2006

Objectives & Methods : I investigated 45 literature of Oriental and Western medicine about the treatment of pain in shoulder and arm. Result and Conclusion : 1. The etiological causes of Pain in Shoulder and Arm based on literatures of Oriental medicine are attack of wind-heat on the lung, wind cold, damp-heat struggle between the vital energy and pathogenic factor and six pathogenic factors. And all these causes are the conception of blockage syndrome, Qi and blood stagnating in meridian system. 2. The treatment of Pain in Shoulder and Arm based on Oriental medicine is mainly composed of both medical therapy for Bi syndrome due to pathogenic wind, deficiency of both Qi and blood, consumption of the liver and the spleen, and also acupuncture and moxibustion treatment by selection for acupoint. And those treatments are for treating etiology. And also there are treatments using the meridian system and Twelve Muscle Region and Ashihyeol for the purpose of treating the symptoms. 3. The etiological causes of Pain in Shoulder and Arm based on literatures of Western medicine are degenerative cut of tendon and nerve symptoms caused by tendonitis, bursitis, calcification, ruptured cervical disc and thoracic outlet syndrome. 4. The treatment of Pain in Shoulder and Arm based on Western medicine is for alleviation of pain, such as giving an anodyne, steroid products, local anesthetic injection and stretching and strengthening the muscles.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.6
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• pp.3619-3623
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• 2013

Background: The scientific evidence relating to the burden of oral diseases attributable to tobacco use has been reviewed and the need for a well-structured dental teaching program concentrating on oral cancer education and tobacco cessation interventions has been emphasized. The aim of our study was to evaluate the awareness of oral cancer and perception of tobacco use cessation counseling among dental students at all study levels in India, Saudi Arabia, the United Arab Emirates, and Yemen. Materials and Methods: A structured, pre-tested, self-administered 15-item questionnaire was used to conduct a cross-sectional survey. Data analyses including percentages, frequency distributions and tests of chi-square were generated. Results: A total of 621 (97.6%) Indian, 493 (96.5%) Saudi, 194 (96.5%) Yemeni and 187 (98.4%) United Arab Emirates respondents recognized the association between oral cancer and cigarette smoking. Although more than 96% of the students surveyed recognized the association between oral cancer and cigarette smoking and about 55% reported cigarette smoking as one of the etiological factors of oral cancer, more than 66% of students who reported cigarette smoking as an etiological factor of oral cancer disagreed/strongly disagreed with all the statements concerning tobacco use cessation. Conclusions: A higher level of oral cancer awareness did not have a positive impact on the perception of tobacco use cessation counseling among the sample surveyed.

• Journal of Haehwa Medicine
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• v.13 no.1
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• pp.225-241
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• 2004

Objectives & Methods: We investigated 45 books to study etiology, pathology and acupuncture & Moxibustion treatment of diarrhea. Result and Conclusion 1. The pathogenic factors of diarrhea are external sensation(外邪感受), jungjishiljo(情志失調), weakness of the spleen and stomach(脾胃虛弱), improper diet(飮食不節), sinyanghueson(腎陽虧損), sueumyujang(水飮留腸), liver Gi invades the sp1een(肝氣乘脾), uhhyuljeche(瘀血阻滯). 2. The etiological cause of diarrhea are closely related to the malfunction of the spleen & stomach(脾胃) and the related jang and bu(臟腑)'s pathological alternation such as spleen & stomach(脾胃), large intestine(大腸), small intestine(小腸), liver(肝), sp1een(脾), and kidney(腎). 3. Acupuncture and moxibustion treatment application of diarrhea with the meridian system are in the following order from the most often mentioned meridian system to the least, urinary bladder meridian(膀胱經), spleen meridian(脾經), stomach meridian(胃經), conception channel meridian(任脈經), liver mehdian(肝經), governor channel meridian(督脈經), large intestine meridian(大腸經), lung meridian(肺經), triple-warmer meridian(三焦經), gall bladder meridian(膽經), Pericardium meridian(心包經). 4. Acupuncture and moxibustion treatment application of diarrhea with meridian point are in the following order from the most often mentioned meridian point to the least, Cheonchu(天樞) sixteen times, Sin-gwol(神厥) fifteen times, Joksamni(足三理), Gwanwon(關元) each twelve times, Daejangsu(大腸兪) eleven times, Taechung(太衝), Bisu(脾兪), Sojangsu(小腸兪) each ten times,Sinsu(腎兪) nine times, CC12(中脘) eight times, Samchosu(三焦兪), gokcheon(曲泉), Harweom(下廉) each seven times, Samgan(三間), Sameungyo(三陰交), Yisa(意舍), Jungnyo, Gyeungmun(京門) each six times, Gyeonggol(京骨), Jangmun(章門) each five times, Sangnyeom(上廉), Hapgok(合谷), Yangmun(梁門), Sanggu(商丘), Yanggang(陽綱), Hoeyang(會陽), Gihyeol(氣穴), Taegye(太谿), Gihae(氣海) each four times.