• Title/Summary/Keyword: Esophageal

Search Result 1,512, Processing Time 0.028 seconds

The Current Evidence on Neoadjuvant Therapy for Locally Advanced Esophageal Squamous Cell Carcinoma

  • Oh, Dongryul;Kim, Jong Hoon
    • Journal of Chest Surgery
    • /
    • v.53 no.4
    • /
    • pp.160-167
    • /
    • 2020
  • Surgical resection is the mainstay of treatment for locally advanced esophageal cancer. Neoadjuvant therapy is recommended to improve survival, based on the results of several randomized trials and meta-analyses. However, controversy remains regarding how to combine surgery, radiotherapy, and chemotherapy. Moreover, in East Asia, the predominant histological type is esophageal squamous cell carcinoma, which has a different epidemiology and tumor biology from esophageal or gastroesophageal junctional adenocarcinoma. As such, the management of esophageal cancer in East Asia seems to be different from that in Western countries. Thus, this article reviews the current evidence on neoadjuvant therapy and considers the optimal combinations and ongoing strategies of multimodal therapy for esophageal squamous cell carcinoma.

Esophageal Reconstruction (식도재건술)

  • 최영호;황재준
    • Korean Journal of Bronchoesophagology
    • /
    • v.4 no.1
    • /
    • pp.15-26
    • /
    • 1998
  • The first successful transthoracic esophagectomy and intrathoracic esophago- gastric anastomosis reported in 1938. Stomach, small intestine, and colon as well as free revascularized grafts have been substituted for excised esophagus. During the past 60 years, there have been substantial advances in preoperative assessment, nutritional support, anesthetic and operative techniques, and postoperative care of patients undergoing esophageal resection and reconstruction. However the hospital mortality and morbidity of esophageal resection and reconstruction is still high and disruption of an intrathoracic esophagogastric anastomosis continues to be the most dreaded complication of esophageal surgery, And the choice of the conduit is still controversial. In this paper, I would like to review the current surgical options available to patients who require esophageal resection and reconstruction as well as the advantages and disadvantages of each technique.

  • PDF

Esophageal Cancer in Korea: Epidemiology and Treatment Patterns

  • Park, Seong Yong;Kim, Dae Joon
    • Journal of Chest Surgery
    • /
    • v.54 no.6
    • /
    • pp.454-459
    • /
    • 2021
  • According to statistics from 2017, esophageal cancer is the fifteenth most common cancer and the eleventh most common cause of cancer-related death in Korea. The most common pathology is esophageal squamous cell carcinoma. Moreover, the incidence of esophageal cancer has been gradually decreasing in Korea, and the percentage of early-stage cases has gradually increased to the point that it is higher than that of other countries. The 5-year relative survival rate has improved over time. Approximately 800 esophagectomy procedures are performed annually. Using a cut-off number of 21 cases per 2 years to define high-volume centers, it was found that 70% of esophagectomies were performed by a few high-volume centers. Unfortunately, there is no nationwide registry or database on esophageal cancer and esophagectomy in Korea. Efforts to establish a nationwide database on esophageal cancer and esophagectomy should be made.

Tracheal and esophageal injury by fish bone

  • Kim, Jae-Bum;Park, Chang-Kwon
    • Korean Journal of Bronchoesophagology
    • /
    • v.14 no.1
    • /
    • pp.42-45
    • /
    • 2008
  • Tracheal injury associated with esophageal injury due to fish bone is very rare. Also, treatment of mediastinitis due to esophageal perforation when it is diagnosed late remains controversial. We report the case that we have successfully experienced treatment of mediastinitis due to tracheal and esophageal injury by fish bone.

  • PDF

Esophageal perforation in children: etiology and management, with special reference to endoscopic esophageal perforation

  • Govindarajan, Krishna Kumar
    • Clinical and Experimental Pediatrics
    • /
    • v.61 no.6
    • /
    • pp.175-179
    • /
    • 2018
  • Perforation of the esophagus is an uncommon problem with significant morbidity and mortality. In children undergoing endoscopy, the risk of perforation is higher when interventional endoscopy is performed. The clinical features depend upon the site of esophageal perforation. Opinions vary regarding the optimal treatment protocol, and the role of conservative management in this context is not well established. Esophageal perforation that occurs as a consequence of endoscopy in children requires careful evaluation and management, as outlined in this article.

The Surgical Treatment of Esophageal Atresia with Tracheoesophageal Fistula -Report of 2 Cases- (선천성 식도폐쇄 및 기관식도루 수술치험 2례)

  • 한동기
    • Journal of Chest Surgery
    • /
    • v.27 no.3
    • /
    • pp.244-250
    • /
    • 1994
  • Early recognition, vigorous preoperative preparation, sophisticated supportive care, control of sepsis, and intensive care nursing have produced remarkably improved results in the management of esophageal atresia. Successful surgery for esophageal atresia and tracheoesophageal fistula was carried out recently. Two neonates with esophageal atresia and distal tracheoesophageal fistula were type C. Transpleural end-to-end repair was carried out after gastrostomy due to low birth weight in case I associated with ventricular septal defect. Case 2 underwent primary retropleural end-to-end repair. A simple one-layer anastomosis with the sutures passing through all layers of`the esophagus was performed in all cases.

  • PDF

Adjuvant Therapy for Esophageal Squamous Cell Carcinoma

  • Sun, Jong-Mu
    • Journal of Chest Surgery
    • /
    • v.53 no.4
    • /
    • pp.168-171
    • /
    • 2020
  • Adjuvant therapy for completely resected esophageal squamous cell carcinoma is less commonly applied in clinical practice than neoadjuvant therapy, but it plays a substantial role in improving survival for esophageal cancer patients. This article presents a concise review of the evidence regarding adjuvant therapy for esophageal squamous cell carcinoma and future directions, particularly immunotherapy.

Congenital Esophageal Atresia Associated with a Tracheobronchial Remnant

  • Wu, Yuhao;Wu, Chun
    • Journal of Chest Surgery
    • /
    • v.52 no.3
    • /
    • pp.170-173
    • /
    • 2019
  • A rare case of esophageal atresia/tracheo-esophageal fistula (EA-TEF) with an associated tracheobronchial remnant (TBR) is reported and discussed herein. A 13-month-old patient was seen with a complaint of vomiting of solid food 1 year after EA-TEF repair. An esophagogram showed a tapered narrowing in the lower segment of the esophagus. A re-operation was carried out and a pathologic examination of the resected stenotic segment revealed the presence of a TBR.

Bronchoesophageal Fistula Associated with Esophageal Diverticulum; A Case Report (식도게실을 동반한 기관지-식도루;수술치험 1례)

  • 최대융
    • Journal of Chest Surgery
    • /
    • v.26 no.7
    • /
    • pp.579-582
    • /
    • 1993
  • We experienced a case of acquired benign bronchoesophageal fistula associated esophageal diverticulum which was treated successfully by division of ~stulous tract and esophageal diverticulectomy.Benign bronchoesophageal fistulas associated with esophageal diverticulum are very rare. This presentation is characterized by paroxysmal cough especially after drinking liquids and is easily diagnosed by esophagogram. We report a case with review of literatures.

  • PDF

Influence of Personal Character on Quality of Life of Patients with Esophageal Cancer in North Henan Province and Influencing Factors

  • Lin, Jian-Ying;Wang, Ming-Sheng;Dong, Liang-Peng;Xu, Da-Wei;Wang, Ying;Li, Xue-Liang;Li, Xiu-Min
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.13 no.11
    • /
    • pp.5415-5420
    • /
    • 2012
  • The aim of this study was to investigate QoL (quality of life) of patients with esophageal cancer in northern Henan province, China, and to accurate evaluate and reflect the relationship between patient characteristics and QoL. In the high risk area of esophageal cancer in the north of Henan province, 735 patients with esophageal cancer were investigated. The Eysenck personality questionnaire (EPQ) and QoL were analyzed by using the questionnaire of general situation, EPQ, QLQ-C30 and QLQ-OES18. The effects of personal character on the QoL of esophageal carcinoma patients were analyzed by SPSS 11.0 software. The QoL of esophageal cancer patients in Northern Henan region was significantly affected by character. The difference between choleric and type of melancholic temperament types was significant (P<0.01), also in OESEAT, OESTA, OESCO and OESSP (P<0.05). Differences in personal character can thus influence the quality of esophageal cancer patient lives.