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A study on improvement of misdiagnosis rate in aortic regurgitation disease by physically correcting EF in 2D echo cardiography (대동맥판 역류질환 진단시 이면성심초음파 박출계수의 보정을 통한 오진율 개선에 관한 연구)

  • Choi, Kwan-Woo;Son, Soon-Yong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.5
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    • pp.2142-2147
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    • 2012
  • This study is aimed at decreasing wrong diagnosis with corrected EF(Ejection Fraction) of 2D echo cardiography by analysing the physical time-resolution difference between Cine MRI and 2D echo cardiography and applying the corrected EF in 2D echocardiography. From February 2010 to December 2011, among the 110 patients who had undergone both 2D echo cardiography and cine MRI only 37 patient were selected suffering aortic valve regurgitation. ED, ES and SV were measured and EF was calculated in each system while normal ranges of Cine MRI and 2D echocardiography were compared to evauate misdiagnosis rate. The correlation of physical time resolution between 2D echocardiography and MRI was evaluated and the differences were corrected with linear regression coefficient which is derived from linear regression analysis. Blandt-Altman plot was used to evaluate the reliability of corrected 2D echo cardiography EF and compare the error among measured values. The values were compared with MRI normal range and misdiagnosis rate was measured again. As a result, misdiagnosis rates of physical time resolution were measured to be 32.4%(12people) before the correction of EF and 18.9%(7people) after the correction. Also, EF confirmed in Blandt-Altman plot were almost the same with MRI EF. In conclusion, when diagnosing aortic regurgitation disease, simply using 2D echocardiography can easily raise the misdiagnosis rates, therefore considering the MRI machine's physical merits, correcting the time resolution difference is important by calculating time resolution wrong diagnosis would decrease and it is considered to be useful in clinical circumstances.

Spatial Estimation of the Site Index for Pinus densiplora using Kriging (크리깅을 이용한 소나무림 지위지수 공간분포 추정)

  • Kim, Kyoung-Min;Park, Key-Ho
    • Journal of Korean Society of Forest Science
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    • v.102 no.4
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    • pp.467-476
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    • 2013
  • Site index information given from forest site map only exist in the sampled locations. In this study, site index for unsampled locations were estimated using kriging interpolation method which can interpolate values between point samples to generate a continuous surface. Site index of Pinus densiplora in Danyang area were calculated using Chapman-Richards model by plot unit. Then site index for unsampled locations were interpolated by theoretical variogram models and ordinary kriging. Also in order to assess parameter selection, cross-validation was performed by calculating mean error (ME), average standard error (ASE) and root mean square error (RMSE). In result, gaussian model was excluded because of the biggest relative nugget (37.40%). Then spherical model (16.80%) and exponential model (8.77%) were selected. Site index estimates of Pinus densiplora throughout the entire area in Danyang showed 4.39~19.53 based on exponential model, and 4.54~19.23 based on spherical model. By cross-validation, RMSE had almost no difference. But ME and ASE from spherical model were slightly lower than exponential model. Therefore site index prediction map from spherical model were finally selected. Average site index from site prediction map was 10.78. It can be expected that regional variance can be considered by site index prediction map in order to estimate forest biomass which has big spatial variance and eventually it is helpful to improve an accuracy of forest carbon estimation.

Repeatability of Monocular Spherical Endpoints Test (단안 구면 끝점검사의 반복성 검증)

  • Kim, Sang-Yeob;Moon, Byeong-Yeon;Cho, Hyun Gug
    • Journal of Korean Ophthalmic Optics Society
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    • v.17 no.2
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    • pp.209-213
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    • 2012
  • Purpose: To assess the repeatability of the monocular spherical endpoints, a test was performed with four methods which are the retinoscopy, the MPMVA (maximum plus maximum visual acuity) method, the R/G duochrome method, and the crossed cylinder method. Methods: The monocular spherical endpoints was measured by four kinds of method (Retinoscopy, MPMVA method, R/G duochrome method, Crossed cylinder method) on 20 subjects (40 eyes) of average age 23.0 year-old men and women. After a week, retest was performed by same procedure and the test-retest repeatability was assessed by using the Bland-Altman plot analysis. Results: The test-retest mean difference of retinoscopy was the smallest diopters of -0.03 and that of R/G duochrome method was the largest diopters of -0.19. The upper/lower 95% limits of agreement for repeatability was the narrowest in retinoscopy and was the widest in crossed cylinder method. When compared the spherical endpoints of each eye between by retinoscopy and by other three methods, the error rate of ${\pm}0.25D$ in total eyes was 85% in MPMVA method, 80% in R/G duochrome method, and 24% in crossed cylinder method. Conclusions: Test-retest repeatability is the highest in the retinoscopy, and the retinoscopy, the MPMVA method, and R/G duochrome method are suitable for monocular spherical endpoints test.

Application of Jackknife Method for Determination of Representative Probability Distribution of Annual Maximum Rainfall (연최대강우량의 대표확률분포형 결정을 위한 Jackknife기법의 적용)

  • Lee, Jae-Joon;Lee, Sang-Won;Kwak, Chang-Jae
    • Journal of Korea Water Resources Association
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    • v.42 no.10
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    • pp.857-866
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    • 2009
  • In this study, basic data is consisted annual maximum rainfall at 56 stations that has the rainfall records more than 30years in Korea. The 14 probability distributions which has been widely used in hydrologic frequency analysis are applied to the basic data. The method of moments, method of maximum likelihood and probability weighted moments method are used to estimate the parameters. And 4-tests (chi-square test, Kolmogorov-Smirnov test, Cramer von Mises test, probability plot correlation coefficient (PPCC) test) are used to determine the goodness of fit of probability distributions. This study emphasizes the necessity for considering the variability of the estimate of T-year event in hydrologic frequency analysis and proposes a framework for evaluating probability distribution models. The variability (or estimation error) of T-year event is used as a criterion for model evaluation as well as three goodness of fit criteria (SLSC, MLL, and AIC) in the framework. The Jackknife method plays a important role in estimating the variability. For the annual maxima of rainfall at 56 stations, the Gumble distribution is regarded as the best one among probability distribution models with two or three parameters.

Effects of Cognition Improvement Programs on Normal Elderly in Korea: A Systematic Review and Meta-Analysis (국내 노인의 인지기능 향상 프로그램의 효과연구: 체계적 문헌고찰과 메타분석)

  • Kim, Kyoungyun;Lee, Eunjoo
    • 한국노년학
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    • v.37 no.2
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    • pp.431-444
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    • 2017
  • This study identified effect size of cognition improvement programs developed for normal elderly in Korea. By searching four databases, 9,624 studies published from 2000 to 2016 were identified. Finally, 14 studies which satisfied the inclusion criteria were selected for meta-analysis. Quality assessment of included studies was conducted using controlled trial checklist of Scottish Intercollegiate Guidelines Network. R version 3.3.2 (2016-10-31) with "meta" and "metafor" package was used to calculate effect sizes, identify the reasons of heterogeneity, and check publication bias. Total effect size of cognition improvement program was middle (SMD=0.759, p<.001, $I^2=34%$). For heterogeneity, moderator analysis was executed and combined program with exercise had the largest effect size (SMD=1.231, p<.001, $I^2=40.8%$). Publication bias was exist by funnel plot and Egger 's regression test, but trim and fill analysis showed that there was no serious error to reverse study results. Therefore, Combined program with exercise for the normal elderly was expected to improve the cognitive function of the normal elderly.

Determination of Survival of Gastric Cancer Patients With Distant Lymph Node Metastasis Using Prealbumin Level and Prothrombin Time: Contour Plots Based on Random Survival Forest Algorithm on High-Dimensionality Clinical and Laboratory Datasets

  • Zhang, Cheng;Xie, Minmin;Zhang, Yi;Zhang, Xiaopeng;Feng, Chong;Wu, Zhijun;Feng, Ying;Yang, Yahui;Xu, Hui;Ma, Tai
    • Journal of Gastric Cancer
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    • v.22 no.2
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    • pp.120-134
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    • 2022
  • Purpose: This study aimed to identify prognostic factors for patients with distant lymph node-involved gastric cancer (GC) using a machine learning algorithm, a method that offers considerable advantages and new prospects for high-dimensional biomedical data exploration. Materials and Methods: This study employed 79 features of clinical pathology, laboratory tests, and therapeutic details from 289 GC patients whose distant lymphadenopathy was presented as the first episode of recurrence or metastasis. Outcomes were measured as any-cause death events and survival months after distant lymph node metastasis. A prediction model was built based on possible outcome predictors using a random survival forest algorithm and confirmed by 5×5 nested cross-validation. The effects of single variables were interpreted using partial dependence plots. A contour plot was used to visually represent survival prediction based on 2 predictive features. Results: The median survival time of patients with GC with distant nodal metastasis was 9.2 months. The optimal model incorporated the prealbumin level and the prothrombin time (PT), and yielded a prediction error of 0.353. The inclusion of other variables resulted in poorer model performance. Patients with higher serum prealbumin levels or shorter PTs had a significantly better prognosis. The predicted one-year survival rate was stratified and illustrated as a contour plot based on the combined effect the prealbumin level and the PT. Conclusions: Machine learning is useful for identifying the important determinants of cancer survival using high-dimensional datasets. The prealbumin level and the PT on distant lymph node metastasis are the 2 most crucial factors in predicting the subsequent survival time of advanced GC.

The physical properties and the dyeability of the easily dyeable polyester yarn under atmospheric pressure (상압가염형 폴리에스테르 섬유의 물성과 염색성)

  • Kim, Tae Gyeong;Yun, Seok Han;Sin, Sang Yeop;Im, Yong Jin;Jo, Gyu Min
    • Textile Coloration and Finishing
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    • v.13 no.6
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    • pp.33-33
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    • 2001
  • The physical properties and the dyeability of the easily dyeable polyester yarn(EDY) were investigated and compared with those of regular polyester (REG-PET). The EDY, copolymerized with small amount of polyethylene glycol(PEG), showed higher intensity of aliphatic CH peak in IR spectrum, lower density and lower compactness than those of the REG-PET from the analysis of IR, density gradient column and XRD respectively. In the physical properties, the EDY has lowers $T_g,\;T_m$, specific stress and initial modulus, and also has higher strain than that of the REG-PET. The EDY can be dyed under atmospheric pressure and its dyeing rate was faster than REG-PET due to low $T_d$, and this seems to be caused by the increased flexibility of Polymer chain in amorphous region of the EDY due to the copolymerization of PEG.ns being within the experimental error, the average values of lifetim. $\tau$(t) are taken for further calculations. Rate constants such as Stern-Volmer quenching constants K$_{sv}$, quenching rate parameters k$_q$ and k''$_q$, static quenching constant V and kinetic distance r are determined using the modified Stern-Volmer eq.tion and sphere of action static quenching model. In order to see whether the reactions are diffusion limited, equations k$_q$ = e$^{-Eq/RT}$ and k''$_q$ = e$^{-Eq/RT}$ are used to determine the values of E$_q$ and E''$_q$, the activati. energies for collisional quenching and the values of E$_q$ are 14.53, 17.28 and 16.20 kJ mole$^{-1}$ for MPNO1, MPNO2 and 2-PI respectively and the values of E''$_q$ are 14.62 and 17.73 for MPNO1 and MPNO2 respectively. From the magnitudes of various quantities it has.een concluded that the reactions are diffusion limited and the observed positive deviations in the S-V plot are due to static and dynamic quenching.

A Study on the Simulation of Beam Trajectory in the Electron-Gun by FDM using the Irregular Mesh (불균등 Mesh를 사용한 유한차분법에 의한 전자총의 Beam 궤적 Simulation에 관한 연구)

  • 김남호;정현열;이무용;정기호
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.16 no.8
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    • pp.719-731
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    • 1991
  • This paper introduces a relatively simple computer simulation method for analyzing trajectory of electron beam in cylindrical electrode of the CRT, which outputs the cutoff voltag, beam current, spot size and plots out the trajectory, rom the input data on physical construction and applied voltages of electron gun. In order to improve computing speed in obtaining potential distibution, the authors have ivided the space into seveal setos and allocated different mesh sizes epending on the acuracy required to each sector and applied the finite difference method in calculation. The plot of trajectoy obtained from the simulation provided useful insight into the focusing mechanism of the CRT. The computed and measured result including beam curent. spot sizs and cutoff voltages for several model guns have ageed within eperimental error. The simulation program enables the designer to compare the effects of varied electrode shpe without the epense of building an actual gun and may be appli in esigning and implementing the electron gun assemply.

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Monitoring Onion Growth using UAV NDVI and Meteorological Factors

  • Na, Sang-Il;Park, Chan-Won;So, Kyu-Ho;Park, Jae-Moon;Lee, Kyung-Do
    • Korean Journal of Soil Science and Fertilizer
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    • v.50 no.4
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    • pp.306-317
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    • 2017
  • Unmanned aerial vehicles (UAVs) became popular platforms for the collection of remotely sensed data in the last years. This study deals with the monitoring of multi-temporal onion growth with very high resolution by means of low-cost equipment. The concept of the monitoring was estimation of multi-temporal onion growth using normalized difference vegetation index (NDVI) and meteorological factors. For this study, UAV imagery was taken on the Changnyeong, Hapcheon and Muan regions eight times from early February to late June during the onion growing season. In precision agriculture frequent remote sensing on such scales during the vegetation period provided important spatial information on the crop status. Meanwhile, four plant growth parameters, plant height (P.H.), leaf number (L.N.), plant diameter (P.D.) and fresh weight (F.W.) were measured for about three hundred plants (twenty plants per plot) for each field campaign. Three meteorological factors included average temperature, rainfall and irradiation over an entire onion growth period. The multiple linear regression models were suggested by using stepwise regression in the extraction of independent variables. As a result, $NDVI_{UAV}$ and rainfall in the model explain 88% and 68% of the P.H. and F.W. with a root mean square error (RMSE) of 7.29 cm and 59.47 g, respectively. And $NDVI_{UAV}$ in the model explain 43% of the L.N. with a RMSE of 0.96. These lead to the result that the characteristics of variations in onion growth according to $NDVI_{UAV}$ and other meteorological factors were well reflected in the model.

The Reliability of Thickness Measurement of the Deep Fiber of the Lumbar Multifidus Using Ultrasonography

  • Jung, Doh-Heon;Kim, Su-Jung;Yi, Chung-Hwi;Cynn, Heon-Seock;Choi, Houng-Sik
    • Physical Therapy Korea
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    • v.17 no.4
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    • pp.49-54
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    • 2010
  • The reliability of the thickness measurement of the lumbar multifidus (LMD using real-time ultrasonography (US) was determined in only the superficial fiber of the lumbar multifidus (SM). However, previous studies have not examined the reliability of the deep fiber of the LM (DM). The purpose of this study was to determine the intrarater and the interrater reliability of the thickness measurements of DM using US. Eleven heathy males participated in the study. The thickness of the DM was measured with an US in the prone position. Reliability was examined using intraclass correlation coefficients (ICC), standard error of the measurement (SEM), and the Bland and Altman plot. ICC(3,1) was used to calculate the interrater reliability of the thickness measurement of DM using the values from both the first and second test sessions. Additionally, ICC(3,1) was used to calculate the intrarater reliability of the measurements over two days using the measurements obtained in test session 1 and lest session 2. The results of this study were as follows: 1) the ICC(3,1) value for interrater reliability was .94 in the first test session, and .93 in the second test session. 2) the ICC(3,1) values for intrarater reliability of the measurements over two days was .90 in both the first examiner and the second examiner. The interrater reliability and interrater reliability of the DM measurements, obtained via the US protocol used in this research was excellent. Therefore, we conclude that the thickness measurement of the DM obtaioned from the US protocol used in this research would be useful for clinician assessment of the thickness of the DM.