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Evaluation of Analyzer and Measurement Conditions of Blood Ammonia (혈중 암모니아의 측정조건과 분석기기의 평가)

  • Kim, Sang-Su;Kim, Myong Soo;Lee, Seung Mo;Park, Chang-Eun
    • Korean Journal of Clinical Laboratory Science
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    • v.48 no.2
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    • pp.68-73
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    • 2016
  • Ammonia is very toxic, and causes neuronal damage via excitotoxicity, oxidative stress, and inflammation. Because the liver is the primary organ for ammonia metabolism, compromised liver function can result from inborn errors of metabolism. Measurement of blood ammonia has some limitations. Recently, several laboratories examined possible concurrent increases in plasma ammonia. However, the collection, handling, storage, and analysis of blood samples are all potential sources of error. For evaluation of rapidity and reliability of measurement of blood ammonia, the DRI-CHEM 100 (Fuji Film Co., Japan) and COBAS 8000 (Roche Diagnostic Ltd., Switzerland) analyzer were used for analysis of ammonia level values. The results of this study detected a high correlation between analyzer. Therefore, one-step measurement was suitable for ammonia analysis. After sampling of the ammonia in the time slot for measurement an increase to 46.5, 57.4, and 79.0 (${\mu}g/dL$) was observed at 30, 90, and 180 minutes. In addition, specific capacity of the ammonia, 7, 10, and 13 (${\mu}L$), was measured as 39, 46, and 43 (${\mu}g/dL$), respectively, and the FDC-100 analyzer was more effective in $10{\mu}L$ (p<0.001). In conclusion, the evaluated analysis may offer useful information for clinical application.

Prediction of Occupant Load Density using People Counting System in Discount Stores (무인계수시스템을 이용한 대형할인점의 재실자밀도 예측)

  • Seo, Dong-Goo;Hwang, Eun-Kyoung
    • Fire Science and Engineering
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    • v.31 no.6
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    • pp.53-59
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    • 2017
  • The purpose of this study is to verify the suitability of the current standards by predicting the density of the occupant load density for discount stores. An internal data survey as well as an actual survey using a People Counting System (PCS) were employed to ascertain the number of occupants and 95% confidence interval of nationwide discount stores. According to the results of the actual survey, the time and days on which the maximum number of occupants were reached was from 16:00 to 18:00 and Christmas Eve and the weekend before New Year's Day, respectively. From the results of the maximum number of occupants, a regression equation was derived from the relationship between the internal data and the amount of sales, and this equation was verified in a previous study. Thus, the internal data of 50 discount stores were analyzed using this process. As a result, the 95% confidence interval was determined to be $2.7{\sim}2.9m^2/pers.$ and the error level was not large compared to the domestic and foreign standards. Therefore, this study proposes that a conservative estimate of the standard occupant load density for discount stores is $2.7m^2/pers.$

Estimation of Measurement Uncertainty in Vitamin C Analysis from Vegetable and Fruit Juice (야채음료 중 비타민 C 분석에 있어서의 측정불확도 추정)

  • Kim, Young-Jun;Kim, Hyeon-Wee
    • Korean Journal of Food Science and Technology
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    • v.35 no.6
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    • pp.1053-1059
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    • 2003
  • This study aimed to determine the amount of vitamin C from vegetable & fruit juice by high performance liquid chromatograhy (HPLC). Components for estimation of measurement uncertainty associated with the analysis of vitamin C, such as standard weight, purity, molecular weight, dilution of standard solution, calibration curve, recovery, and precision, were importantly applied. The estimation of uncertainty obtained with systematic and random error based on the GUM (Guide to the expression of uncertainty in measurement) and EURACHEM document with mathematical calculation and statistical analysis. The components, evaluated ty either Type A or Type B methods, were combined to produce an overall value of uncertainty known as the combined standard uncertainty. An expanded uncertainty was obtained by multiplying the combined standard uncertainty with a coverage factor (k) calculated from the effective degree of freedom. The content of vitamin C from vegetable and fruit juice was 27.53 mg/100g and the expanded uncertainty by multiplying by the coverage factor (k, 2.06) was 0.63 mg/100g at a 95% confidence level. It was concluded that the main sources were, in order of recovery and precision, weight and purity of the reference material, dilution of the standard solution, and calibration curve. Careful experiments on other higher uncertainties is further needed in addition to better personal proficiency in sample analysis in terms of accuracy and precision.

Manufacture Lenticular Map of Golf Courses Using Digital Orthophoto (수치정사영상을 이용한 렌티큘러 코스맵 제작)

  • Kim, Kam-Lae;Cheong, Hae-Jin;Cho, Won-Woo
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.25 no.5
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    • pp.475-482
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    • 2007
  • Most golfers believe that knowing yardages will improve their score. Certainly it helps with club selection. But, simple "Graphic" yardage guides being notorious for error and inaccuracies, which a serious golfer will pick immediately, only serve to erode the players enjoyment and ultimately, golf course satisfaction. Someone believes with low-level aerial photographic images, golfer will be impressed with the accuracy of the depiction, helping them play a more confident game. But, there are no mapping products in true 3-D available in the world that allows a golfer to determine shot distances in yards or meters. So, we suggest an lenticular technology for real 3-D display as a viable alternative to conventional image map solution. This technology is an image display method for the generation of multi-image effects like 3D visualization or animation. This methodology is cutting edge stereoscopic image which overcomes the limitation of conventional photo tech by recomposing and producing 3 dimensional images. A significant strength of this methods its versatility concerning display effects. The main use of the hardcopy 3-D lenticular displays is in the fields of science, education, planning, and representation. This paper gives a concise overview of the lenticular foil technology and describes the production of the true 3-D yardage book of golf courses. For this study, 3-D effects are achieved and evaluated with the lenticular display by incorporation multiple synthetic images based on digital topographic terrain model and by using the two images of the actual stereopair.

Development of Gait Event Detection Algorithm using an Accelerometer (가속도계를 이용한 보행 시점 검출 알고리즘 개발)

  • Choi, Jin-Seung;Kang, Dong-Won;Mun, Kyung-Ryoul;Bang, Yun-Hwan;Tack, Gye-Rae
    • Korean Journal of Applied Biomechanics
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    • v.19 no.1
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    • pp.159-166
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    • 2009
  • The purpose of this study was to develop and automatic gait event detection algorithm using single accelerometer which is attached at the top of the shoe. The sinal vector magnitude and anterior-posterior(x-axis) directional component of accelerometer were used to detect heel strike(HS) and toe off(TO), respectively. To evaluate proposed algorithm, gait event timing was compared with that by force plate and kinematic data. In experiment, 7 subjects performed 10 trials level walking with 3 different walking conditions such as fast, preferred & slow walking. An accelerometer, force plate and 3D motion capture system were used during experiment. Gait event by force plate was used as reference timing. Results showed that gait event by accelerometer is similar to that by force plate. The distribution of differences were spread about $22.33{\pm}17.45m$ for HS and $26.82{\pm}14.78m$ for To and most error was existed consistently prior to 20ms. The difference between gait event by kinematic data and developed algorithm was small. Thus it can be concluded that developed algorithm can be used during outdoor walking experiment. Further study is necessary to extract gait spatial variables by removing gravity factor.

The Effect of Six Sigma Activity in Major Trauma Patients on the Time Spent in the Emergency Department (Six Sigma 활동을 통한 중증외상환자의 응급실 체류시간 개선 활동)

  • Kim, Hyun-Soo;Kim, Ok-Jun;Choi, Sung-Wook;Kim, Eui-Chung;Park, Young-Tae;Ko, Tae-I;Cho, Yun-Kyung
    • Journal of Trauma and Injury
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    • v.23 no.2
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    • pp.119-127
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    • 2010
  • Purpose: This study was conducted to shorten the time spent at each stage of treatment and to reduce the total amount of time patients spend in the emergency department (ED) by applying Six Sigma in the treatment of major trauma patients. Methods: This is a comparative study encompassing 60 patients presenting to the ED of Bundang CHA Hospital from January 2008 to December 2008 and from July 2009 to March 2010. The stages of treatment for major trauma patients were divided into six categories (T1: total emergency department staying time, T2: duration of visit-radiologic evaluation time, T3: duration of visit-consult to department of admission, T4: duration of consultation-issue of hospital admissions time, T5: duration of visit-issue of hospital admissions time, T6: duration of issue of hospital admission-emergency department discharge time) and the total time patients spent in the ED was compared and analyzed for periods; before and after the application of Six Sigma. Results: After the application of Six Sigma, the numerical values in four of the six categories were significantly reduced; T2, T3, T4, and T5. However, the average of the total time patients spent in the ED did not show any remarkable change because the T6 increased highly. The level of Six Sigma increased $0.17{\sigma}$. Conclusion: The application of Six Sigma for major trauma patients in the ED resulted in a significant improvement in the error rate for the total time patients spent in the ED. The Six Sigma activity has shown great potential. Therefore, the project is expected to bring better results in every stage of treatment if the levels of the hospital facilities are improved.

Effects of Zoning Structure on Travel Demand Forecasts (존 체계 구축이 교통수요 추정에 미치는 영향에 관한 연구)

  • Han, Myeong-Ju;Seong, Hong-Mo;Baek, Seung-Han;Im, Yong-Taek;Lee, Yeong-In
    • Journal of Korean Society of Transportation
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    • v.29 no.1
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    • pp.17-27
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    • 2011
  • This paper investigates some critical errors influencing travel demand estimation in Korea Transportation Data Base (KTDB), and through this investigation reasonable traffic analysis zone (TAZ) size and internal trips ratio are analyzed. With varying zone size, the accuracy of travel demand estimation is studied and appropriate level of zone size in KTDB is also presented. For this purpose zonal structure consisting of location of zone centroid, number of centroid connecters has been constructed by social economic index, and then some descriptive statistical analyses such as F-test, coefficient of correlation are performed. From the results, this paper shows that the optimum levels of zone system were various according to the order and capacity of roads, and also shows that the smaller TAZ, the less error in this research. In conclusion, in order to improve accuracy of traffic demand estimation it is necessary to make zone size smaller.

Analyzing Vomit of Platalea minor (Black-faced Spoonbill) to Identify Food Components using Next-Generation Sequencing and Microscopy (차세대염기서열 및 현미경 분석을 통한 저어새의 토사물 내 먹이생물 분석)

  • Kim, Hyun-Jung;Lee, Taek-Kyun;Jung, Seung Won;Kwon, In-Ki;Yoo, Jae-Won
    • Korean Journal of Environmental Biology
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    • v.36 no.2
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    • pp.165-173
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    • 2018
  • We sampled vomit of black-faced spoonbills(Platalea minor) during the brood-rearing season (from June 2011 to June 2014) at the Namdong reservoir in Incheon and analyzed the food components in the vomit using microscopy and next-generation sequencing (NGS). Microscopic observations primarily helped in identifying osteichthyes (bony fishes), crustaceans, and polychaetes. In particular, species belonging to the families Mugilidae and Gobiidae among the fish, and Macrophthalmus japonicas among the crustaceans, were observed at high frequency. Results of NGS analysis revealed the predominant presence of bony fish (42.58% of total reads) and crustaceans (40.75% of total reads), whereas others, such as polychaetes (12.66%), insects (0.24%), and unidentified species (3.78%), occurred in lower proportions. At the species level, results of NGS analysis revealed that Macrophthalmus abbreviates and Macrobrachium sp. among the crustaceans, and Acanthogobius hasta, Tridentiger obscurus, and Pterogobius zacalles among the bony fish, made up a high proportion of the total reads. These food species are frequently found at tidal flats in the Songdo and Sihwa lakes, emphasizing the importance of these areas as potential feeding sites of the black-faced spoonbill. Feed composition of the black-faced spoonbill, as evaluated by analyzing its vomit, differed when the evaluations were done by microscopic observation or by NGS analysis. Evaluation by microscopic observation is difficult and not error free, owing to the degradation of the samples to be analyzed; however, NGS analysis is more accurate, because it makes use of genetic information. Therefore, accurately analyzing food components from morphologically indistinguishable samples is possible by using genetic analysis.

Design of a New 3-D 16-ary Signal Constellation with Constant Envelope (상진폭 특성을 가지는 새로운 3차원 16진 신호성상도의 설계)

  • Choe, Chae-Cheol;Kang, Seog-Geun
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.15 no.10
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    • pp.2149-2156
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    • 2011
  • In this paper, design of a new 3-dimensional (3-D) 16-ary signal constellation with constant envelope is presented and analyzed. Unlike the conventional 16-ary constellations, all signal points of the new constellation are uniformly located on the surface of a sphere so that they have a unique amplitude level and a symmetrical structure. When average power of the constellations is normalized, the presented 16-ary constellation has around 11.4% increased minimum Euclidean distance (MED) as compared to the conventional ones that have non-constant envelope. As a result, a digital communication system which exploits the presented constellation has 1.2dB improved symbol error rate (SER). While signal points of the conventional constant-envelope constellation are not distributed uniformly on the surface of a sphere, those of the proposed constellation has a completely symmetric distribution. In addition, the new signal constellation has much lower computational complexity for practical implementation than the conventional one. Hence, the proposed 3-D 16-ary signal constellation is appropriate for the application to a communication system which strongly requires a constant-envelope characteristic.

An Action Information Management Method for Creating Adaptive NPC (적응형 NPC를 생성하는 행동 정보 관리 기법)

  • Kim, Na-Ra;Um, Ky-Hyun;Cho, Kyung-Eun
    • Journal of Korea Game Society
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    • v.8 no.1
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    • pp.103-113
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    • 2008
  • Although people have had more opportunities to enjoy various types of game, most of players have felt less satisfaction with the games. This is the reason that since most Non-player Characters (NPCs) are simple and uniform, they have some limitations for competing with a variety of players. Thus, technologies for creating intelligent NPCs that can compete with each player at a similar level are required. In this paper, we present an action information management method for creating adaptive NPCs based on the algorithm for calculating their action efficiency. This algorithm is useful to the adaptation method for saving and controlling player-appropriate action. In our method, adaptive NPCs observe the actions of players and collect the relationship data between status and action. The efficiency value of the action data is calculated and data of similar status are grouped, and finally stored at the action database. The game system of NPC updates the action database and stores diverse actions. Then, NPC selects action with high efficiency value. We have tested our algorithm on an action game. A random test subject performed a one-on-one game against an adaptive NPC in real-time. As a result, the action dispositions of both the subject and NPC are analyzed in a log file to determine whether or not the disposition of the subject is similar to that of the NPC. The statistics of the diverse test results shows that NPCs become adaptive to players with error rate within less than 6%.

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