• Journal of the Korean Geographical Society
• /
• v.36 no.4
• /
• pp.458-473
• /
• 2001

The classified map of geomorphic surfaces is the most basic data for the geomorphological research. Up to recent days, the traditional methods extracting specific geomorphic surfaces are accomplished by analyzing the aerial photographs and topographical maps, and field works. Also it needs a lot of time and expertness. Furthermore it is difficult to gain the aerial photographs in Korea. Since digital maps in Korean Peninsula are almost completed recently, we tried to extract specific surfaces by analyzing the characteristics of marine terraces based on the level of paleoshoreline and slope analysis on the terrace surface using GIS. However, research used GIS was hardly found up to date, therefore many problems are not be solved yet. The aim of this study is to develop the more efficient and objective method for the extraction and classification of specific geomorphic surfaces by using GIS in Gampo-eup, Gyeongju city, Southeastem Coast in Korea, where a lot of traditional research has already accomplished. For this aim, we have designed the process of extracting specific geomorphic surfaces, chosen the factors that was Gyeongiu city, Southeastem Coast in Korea, where a lot of traditional research has already accomplished. For this aim, we have designed the process of extracting specific geomorphic surfaces, chosen the factors that was suitable for classification of specific geomorphic surface, and presented method of setting up optimum criteria of extraction. As last, effectiveness and problems of these methods were investigated through conincidence rate and error rate.

• Journal of Radiation Protection and Research
• /
• v.42 no.2
• /
• pp.83-90
• /
• 2017

Background: Different cases exist in the measurement of thyroid radiobioassays owing to the individual characteristics of the subjects, especially the potential variation in the counting efficiency. An In situ Object Counting System (ISOCS) was developed to perform an efficiency calibration based on the Monte Carlo calculation, as an alternative to conventional calibration methods. The purpose of this study is to evaluate the applicability of ISOCS to thyroid radiobioassays by comparison with a conventional thyroid monitoring system. Materials and Methods: The efficiency calibration of a portable high-purity germanium (HPGe) detector was performed using ISOCS software. In contrast, the conventional efficiency calibration, which needed a radioactive material, was applied to a scintillator-based thyroid monitor. Four radioiodine samples that contained $^{125}I$ and $^{131}I$ in both aqueous solution and gel forms were measured to evaluate radioactivity in the thyroid. ANSI/HPS N13.30 performance criteria, which included the relative bias, relative precision, and root-mean-squared error, were applied to evaluate the performance of the measurement system. Results and Discussion: The portable HPGe detector could measure both radioiodines with ISOCS but the thyroid monitor could not measure $^{125}I$ because of the limited energy resolution of the NaI(Tl) scintillator. The $^{131}I$ results from both detectors agreed to within 5% with the certified results. Moreover, the $^{125}I$ results from the portable HPGe detector agreed to within 10% with the certified results. All measurement results complied with the ANSI/HPS N13.30 performance criteria. Conclusion: The results of the intercomparison program indicated the feasibility of applying ISOCS software to direct thyroid radiobioassays. The portable HPGe detector with ISOCS software can provide the convenience of efficiency calibration and higher energy resolution for identifying photopeaks, compared with a conventional thyroid monitor with a NaI(Tl) scintillator. The application of ISOCS software in a radiation emergency can improve the response in terms of internal contamination monitoring.

• Journal of Korea Water Resources Association
• /
• v.48 no.10
• /
• pp.807-816
• /
• 2015

In general, the water stage-discharge relationship curve is established based on the assumptions of linearity and homoscedasticity. However, the relationship between the water stage and discharge is affected from geomorphological factors, which violates the basic assumptions of the water stage-discharge relationship curve. In order to reduce the error due to the violations, the curve is divided into several sections based on the manager's judgement considering change of cross-sectional shape. In this research, the objective-splitting criteria of the curve is proposed based on the measured data without the subjective decision. First, it is assumed that the coefficient of variation follows the normal distribution. Then, if the newly calculated coefficient of variation is outside of the 95% confidential interval, the curve is divided. Namely, the groups is divided by the characteristics of the coefficient of variation and the reasonable criteria is provided for establishing a multi-segmented rating curve. To validate the proposed method, it was applied to the data generated by three artificial power functions. In addition, to confirm the applicability of the proposed method, it is applied to the water stage and discharge data of the Muju water stage gauging station and Sangegyo water stage gauging station. As a result, it is found that the automatically divided rating curve improves the accuracy and extrapolation accuracy of the rating curve. Finally, through the residual analysis using Shapiro-Wilk normality test, it is confirmed that the residual of water stage-discharge relationship curve tends to follow the normal distribution.

• Tuberculosis and Respiratory Diseases
• /
• v.78 no.4
• /
• pp.315-320
• /
• 2015

Background: The efficacy of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy can be measured based on the rate of treatment response, based on the Response Evaluation Criteria in Solid Tumors (RECIST) criteria or progression-free survival (PFS). However, there are some patients harboring sensitive EGFR mutations who responded poorly to EGFR-TKI therapy. In addition, there is variability in the PFS after EGFR-TKI treatment. Methods: We performed a retrospective analysis of the medical records of 85 patients with non-small cell lung cancer, who had achieved a stable disease or better response at the first evaluation of treatment response, after receiving a 2-month course of gefitinib. We calculated the tumor shrinkage rate (TSR) by measuring the longest and perpendicular diameter of the main mass on computed tomography before, and 2 months after, gefitinib therapy. Results: There was a significant positive correlation between the TSR and PFS (R=0.373, p=0.010). In addition, a simple linear regression analysis showed that the TSR might be an indicator for the PFS ($B{\pm}standard$ error, $244.54{\pm}66.79$; p=0.001). On univariate analysis, the sex, histologic type, smoking history and the number of prior chemotherapy regimens, were significant prognostic factors. On multivariate regression analysis, both the TSR (${\beta}$=0.257, p=0.029) and adenocarcinoma (${\beta}$=0.323, p=0.005) were independent prognostic factors for PFS. Conclusion: Our results showed that the TSR might be an early prognostic indicator for PFS in patients receiving EGFRTKI therapy.

• Journal of the Korean Society of Marine Environment & Safety
• /
• v.25 no.2
• /
• pp.139-150
• /
• 2019

Though, fishing vessel accidents account for 70 % of all maritime accidents in Korean waters, most research has focused on identifying causes and developing mitigation policies in an attempt to reduce this rate. However, predicting and evaluating accident risk needs to be done before the implementation of such reduction measures. For this reasons, we havve performed a risk analysis to calculate the risk of accidents and propose a risk criteria matrix with 4 quadrants, within one of which forecasted risk is plotted for the relative comparison of risks. For this research, we considered 9 types of fishing vessel accidents as reported by Korea Maritime Safety Tribunal (KMST). Given that no risk evaluation criteria have been established in Korea, we established a two-dimensional frequency-consequence grid consisting of four quadrants into which paired frequency and consequence for each type of accident are presented. With the simple structure of the evaluation model, one can easily verify the effect of frequency and consequence on the resulting risk within each quadrant. Consequently, these risk evaluation results will help a decision maker employ more realistic risk mitigation measures for accident types situated in different quadrants. As an application of the risk evaluation matrix, accident types were further analyzed using accident causes including human error (factor) and appropriate risk reduction options may be established by comparing the relative frequency and consequence of each accident cause.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.25 no.3
• /
• pp.85-91
• /
• 2021

Type 1 and type 2 buildings must regularly conduct precise safety inspections and precise safety diagnosis for the safety and maintenance of facilities, and the safety grade of the building is determined according to the results of the implementation. In addition, the cycle of inspection and diagnosis is determined according to the safety grade of the building. In order to determine the safety grade of the building, a precise safety inspection conducts condition evaluation, and a precise safety diagnosis conducts condition evaluation and safety evaluation. Therefore, since the inspection and diagnosis cycle is determined according to the safety grade of the building, the condition evaluation and safety evaluation must be precise. However, in the case of member unit evaluation, which is the first step in evaluating the current condition, the evaluation grade is determined by using the representative value of the measurement result, and this may result in an error in the evaluation grade. To solve this problem, this study analyzed evaluation criteria for each evaluation item and presented evaluation criteria using inequalities to respond to measurement results and evaluation scores. In addition, we present a functional formula that can reflect performance scores for each evaluation item.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.28 no.3A
• /
• pp.341-347
• /
• 2008

Among coating systems used for steel bridge coatings on highway such as red lead-pigmented alkyd, chlorinated rubber, waterborne inorganic zinc, inorganic zinc/epoxy/urethane and inorganic zinc/epoxy/fluororesin, evaluation of deterioration degree and prediction of lifetime through regression analysis were carried out for coating systems widely used and grossly degraded. For evaluation of deterioration degree, 75 bridges on highway were selected, and evaluations were carried out according to point offering method regulated by Guideline of maintenance coating for steel bridges used in Korea Expressway Corporation. Lifetime prediction results showed 13.0~13.3 years for the whole nation, 11.8 years for urban and industrial region in the metropolitan area, 13.2 years for rural region except the metropolitan area, 13.5~13.7 years for chlorinated rubber coating systems, and 12.86 years for red lead-pigmented alkyd systems. For prediction of the rest life of coating, we tried to execute parallel translations of standard deterioration curve to current life and deterioration degree for both x and y axes, and it was thought that parallel translation for x axis corresponded to deterioration aspects in actual environment. Maximum and minimum equations were derived from standard deterioration equation by adding and subtracting error values deduced in regression analysis to/from each coefficient in order to establish maintenance coating criteria for overall steel bridges on highway. Whole domain was divided into 8 parts in order to predict the rest life of coating and optimum time of maintenance coating, and maintenance coating criteria for each 8 domains were presented.

• Korean Chemical Engineering Research
• /
• v.62 no.1
• /
• pp.70-79
• /
• 2024

Raman analyzer is an analytical technique that utilizes the "Raman effect", which occurs when light is scattered by the inherent vibrations of molecules. It is used for molecular identification and composition analysis. In the natural gas industry, it is widely used in bunkering and tank lorry fields in addition to LNG export and import terminals. In this study, a LNG-specific Raman analyzer was installed and operated under actual field conditions to analyze the composition and principal properties (calorific value, reference density, etc.) of LNG. The measured LNG composition and calorific value were compared with those obtained by conventional gas chromatograph that are currently in operation and validated. The test results showed that the Raman analyzer provided rapid and stable measurements of LNG composition and calorific value. When comparing the calorific value, which serves as the basis for LNG transactions, with the results from conventional gas chromatograph, the Raman analyzer met the acceptable error criteria. Furthermore, the measurement results obtained in this study satisfied the accuracy criteria of relevant international standards (ASTM D7940-14) and demonstrated similar outcomes compared to large-scale international demonstration cases.

• Clinical and Experimental Vaccine Research
• /
• v.13 no.3
• /
• pp.242-252
• /
• 2024

Purpose: In this study, an in-house enzyme-linked immunosorbent assay (ELISA) was developed and validated. The titer of ELISA was calculated using the reference line (RFL) method based on the standard curve drawn using the international reference anti-mouse serum NIBSC (National Institute for Biological Standards and Control) 97/642. Materials and Methods: In the development step, signal to noise was depicted to select the buffers that showed the most appropriate ratio. In the validation step, standard range, precision, dilution linearity, and specificity were confirmed, and RFL and parallel line (PLL) methods were compared in precision and dilution linearity. Results: Coating concentration for plate was achieved at 0.1 ㎍/mL for pertussis toxin (PT), 0.15 ㎍/mL for filamentous hemagglutinin antigen (FHA), and 0.25 ㎍/mL for pertactin (PRN). The signal to noise ratio was 22.02 for PT, 14.93 for FHA, and 8.02 for PRN with 0.25% goat serum in phosphate-buffered saline (PBS) as a dilution buffer, and 2% skim milk in PBS as a blocking buffer. Based on the precision results, we assessed the lower limit of quantification by 1, 0.2, and 1.5 EU/mL concentration for PT, FHA, and PRN which met the ICH (International Council for Harmonization) M10 criteria of a 25% accuracy and total error of 40%. In specificity, homologous serum was spiked into heterologous serum and the accuracy met the criteria. There was no difference in the results between RFL and PLL calculations (p-value=0.3207 for PT, 0.7394 for FHA, 0.2109 for PRN). Conclusion: ELISA validated with RFL calculation method in this study is a relatively accurate assay for mouse humoral immunogenicity test.

• Journal of Korean Society of Forest Science
• /
• v.77 no.1
• /
• pp.23-31
• /
• 1988

A total of 320 Larix leptocepzs Trees growing in Kyonggi and Kangwon Province were examined to estimate tree volume and height with DBH and age. The criteria of selecting the "best" regression equation were based on coefficient of determination, $R^2$, adjusted standard error, I, and the ease of application. From the results obtained in this study, the method of estimating tree volume and height with DBH and age showed the following advantages ; 1. Since no measurement of tree height is needed, it saves time and labor in forest survey. 2. It has the ease of application because age is determined directly in artificial forests. 3. Volume and height can be estimated more easily and accurately with DBH and age than other methods.