• 한국치위생학회지
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• 제20권5호
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• pp.763-771
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• 2020

Objectives: Erigeron bonariensis is a type of Erigeron found throughout the tropical and subtropical areas as one of the perennial plants or pioneer plants. It is known to show detoxifying, antipyretic, and anticancer effects for various cancers. However, there are no reports on the anticancer effect of E. bonariensis on oral cancer cells. In the present study, we investigated the effects of the methanol extract of Erigeron bonariensis (MEEB) on the inhibition of cell growth and induction of apoptosis in mucoepidermoid carcinoma (MEC) cell lines, including the MC3 and YD15 oral cancer cells. Methods: MC3 Cells were treated by dimethyl sulfoxide (DMSO) or methanol extracts of 20 various natural products 20 ㎍/mL for 48 hours and cell viability were analyzed as Trypan blue exclusion assay. The effects of MEEB treatment on the cell viability of MC3 and YD15 cells, for 48 h, were analyzed by Trypan blue exclusion assay. The anticancer efficacy and apoptosis of oral cancer cell lines were analyzed by western blot analysis. The statistical significance of differences between groups was analyzed by Student's two-tailed t-test. A value of P<0.05 compared to the vehicle control was considered statistically significant. Results: Among 20 different naturally derived products, MEEB significantly inhibited cell viability and increased cleaved poly [ADP-ribose] polymerase 1 (PARP) protein in the MC3 and YD15 cells in a concentration-dependent manner. Conclusions: These results suggest that MEEB can be used as a natural anticancer drug for the treatment of human oral cancer.

• 한국환경생태학회지
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• 제17권2호
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• pp.123-132
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• 2003

본 조사는 2002년 7월부터 9월까지 진도군 가사도에서 도서연안 폐염전의 식생 현황을 조사하기 위하여 Braun-Blanquet and Elenberg의 방법에 따라 21개의 방형구(1${\times}$1m, 1${\times}$2m)를 설치하여 생태학적 조사하였다. 조사된 폐염전의 관속식물은 17과 48종이며, 이중에서 염생식물은 20종(42%), 중성식물은 28종 (58%)이 나타났다. 또한 폐염전에서 서식지의 교란은 염생식물의 교란으로 나타났으며, 이 지역에서 귀화식물은 오리새, 달맞이꽃, 망초, 코스모스 등의 23종이 분포하고, 이중에서 중성식물이 20종(71%) 분포하고 있었다. 식생군락은 염생식물 초지군락은 갯질경군락, 갯개미자리군락, 칠면초군락, 습지 초지군락은 갈대군락, 천일사초군락, 가는잎모새달군락, 중성 초지군락은 실망초군락과 갯당근군락 등으로 구분되었다. 각 군락들의 폐염전에서 식생의 구조, 분포, 변화에 대해서 설명하고, 식생표와 현존식생도를 작성하였다.