• Journal of Korean society of Dental Hygiene
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• v.20 no.5
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• pp.763-771
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• 2020

Objectives: Erigeron bonariensis is a type of Erigeron found throughout the tropical and subtropical areas as one of the perennial plants or pioneer plants. It is known to show detoxifying, antipyretic, and anticancer effects for various cancers. However, there are no reports on the anticancer effect of E. bonariensis on oral cancer cells. In the present study, we investigated the effects of the methanol extract of Erigeron bonariensis (MEEB) on the inhibition of cell growth and induction of apoptosis in mucoepidermoid carcinoma (MEC) cell lines, including the MC3 and YD15 oral cancer cells. Methods: MC3 Cells were treated by dimethyl sulfoxide (DMSO) or methanol extracts of 20 various natural products 20 ㎍/mL for 48 hours and cell viability were analyzed as Trypan blue exclusion assay. The effects of MEEB treatment on the cell viability of MC3 and YD15 cells, for 48 h, were analyzed by Trypan blue exclusion assay. The anticancer efficacy and apoptosis of oral cancer cell lines were analyzed by western blot analysis. The statistical significance of differences between groups was analyzed by Student's two-tailed t-test. A value of P<0.05 compared to the vehicle control was considered statistically significant. Results: Among 20 different naturally derived products, MEEB significantly inhibited cell viability and increased cleaved poly [ADP-ribose] polymerase 1 (PARP) protein in the MC3 and YD15 cells in a concentration-dependent manner. Conclusions: These results suggest that MEEB can be used as a natural anticancer drug for the treatment of human oral cancer.

• Korean Journal of Environment and Ecology
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• v.17 no.2
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• pp.123-132
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• 2003

This ecological study investigated the vegetation changes of abandoned salt field, 21 plots(1${\times}$lm, 1${\times}$2m) set up by the methods of Braun-Blanquet and Elenberg in a coastal island, Gasado, Jindogun, from July to September,2002. The vascular plants of abandoned salt field in the surveyed site identified 17 families and 48 species. Of these species, halophytes and mesophytes were 20(42%) and 28(58%) species. In addition, the disturbance to this habitat led to the change of halophytes in abandoned sald field, exotic plants was distributed 23 species, which included Dactylis glomerata, Conyza canadensis, Oenothera odorata, Cosmos bipinnatus, etc., in the group of, mesophytes were 20(71%) species, vegetation communities were classified into 3 community types, i.e. the halophyte grassland community(Limonium tetragonum community, Suaeda japonica community, Spergularia marina community), the wetland grassland community(Phragmites communis community, Carex scabrifolia community, Phaceturus latifolius var. angustifolius community), and the mesophyte grassland community(Erigeron bonariensis community, Daucus littoralis var. koreana community). Each communities was described the structual, distribution and changes of the vegetation in the abandoned salt field, the vegetation table and actual vegetation map were prepared.