• 대한치과교정학회지
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• 제33권1호
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• pp.63-72
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• 2003

최근 치의학이 눈부시게 발전하고, 소득이 증가하면서 이에 따라 일반인의 의식이 점차 변하면서 외모에 대한 관심도도 점차 높아지고 있다. 본 연구는 내원환자의 부정교합의 유형, 치료방법의 변화를 파악하여 내원환자와 보다 적절한 의사소통을 위한 정보를 제공하고, 교정치료 요구의 특성을 파악하여 부정교합의 역학적 자료를 제공하고자 본 연구를 시행하였다. 이를 위해 2002년 상반기와 1992년 상반기에서 울대학교 치과병원 교정과에 내원한 환자 중 진료기록부가 잘 보존된 676명을 대상으로 하여 부정교합의 유형과 내원 환자의 지역분포 및 주소의 변화, 치료방법의 변화를 조사 연구한 결과 다음과 같은 결론을 얻었다. 1 내원 환자의 남녀 비율은 1992년 1:2.1에서 2002년 1:1.5로 남자환자가 많이 증가했음을 알 수 있다. 2. 연령별 내원 환자의 분포에서 2002년에는 7세에서 12세군이 $32.0\%$로 가장 높게 나타났으며, 그 다음으로는 19세에서 24세군이 $24.0\%$, 13세에서 18세군이 $21.6\%$, 25세 이상군이 $14.2\%$, 4세에서 6세군이 $5.8\%$, 0세에서 3세군이 $2.4\%$로 가장 낮았다. 1992년도 내원 환자의 연령 분포와 비교시 성인 환자의 비중이 증가하였다. 3. Angle분류법에 의한 내원환자의 분포에서 2002년에는 III급 부정교합이 $48.1\%$로 가장 높게 나타났으며, I급 부정교합이 $25.0\%$, II급 1류 부정교합이$20.9\%$, II급 2류 부정교합이 $3.4\%$로 나타났다. 4. 내원환자의 지역별 분포에서 서울 북동지역의 환자가$37.0\%$, 서울 남동지역이 $13.2\%$, 서울 남서지역이 $12.3\%$, 서울 북서지역의 환자가 $5.5\%$로 나타났다. 1992년도와 비교시 서울 북동지역환자의 내원 비율이 종가하고 그 외 지역 내원 환자의 비율은 감소한 것으로 나타났다. 5. 주소(chief complaint)별 내원 환자의 분포는 2002년에 하악 전돌이 $17.5\%$로 가장 높게 나타났으며, 크라우딩이 $14.2\%$, 안면 비대칭이 $11.8\%$로 나타났다. 1992년의 주소별 내원 비율과 비교시 안면 비대칭을 주소로 내원한 환자의 비율이 유의하게 증가하였고, 내원 동기가 매우 다양해졌다. 5. 2002년도 내원 환자의 치료방법은 고정식 장치가 $38.0\%$, 악교정 수술이$25.0\%$, 성장 관찰이 $13.0\%$로 나타났다. 1992년도와 비교시 chin cap의 사용이 줄었으며, 상대적으로 악교정 수술과 성장관찰을 요하는 환자의 비중이 유의할만하게 증가하였다

• 농촌의학ㆍ지역보건
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• 제36권1호
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• pp.25-35
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• 2011

본 연구는 성인의 사회적 지지와 우울 정도를 파악하고, 일반적 특성에 따라 사회적 지지와 우울 정도를 비교하며, 사회적 지지와 우울 간에 관계를 분석하여 우울에 미치는 사회적 지지의 효과를 파악함으로써, 우울 예방 및 관리를 위한 기초 자료를 제공하기 위하여 수행되었다. 본 연구의 자료는 제주특별자치도에서 지원하여 수행한 '제주도민 우울실태조사' 연구과제의 원시 자료를 이용하여 이차분석 하였으며, 연구대상은 제주지역에서 계층적 무작위 집락 표출법을 이용하여 선정한 750가구의 성인이었으며, 24명의 훈련된 조사원이 2007년 11월부터 12월까지 가구면접조사를 통해 수집한 1,155명의 자료를 분석하였다. 우울은 The Center for Epidemiologic Studies Depression (CES-D)를 이용하였고, 사회적 지지는 The Medical Outcomes Study (MOS) Social Support Survey 도구를 이용하였다. 연구결과, 우울은 평균 11.35점이었고. 사회적 지지는 평균 75.53점이었다. 주관적 건강수준이 낮을수록, 스트레스가 높을 수록, 학력이 낮을수록, 결혼상태가 미혼이거나 배우자가 있는 경우보다 이혼 및 사별인 경우, 사회경제적 수준이 낮을수록, 종교가 없는 경우 우울 정도는 더 높은 것으로 나타났다. 이 여섯개의 독립변수가 설명하는 변량은 29.8%였고, 회귀모형은 유의하였다. 사회적 지지가 포함되었을 때, 결혼상태, 사회경제적 수준, 종교는 유의하지 않았고, 사회적 지지와 주관적 건강수준, 스트레스, 교육수준은 우울에 유의한 영향을 주는 것으로 나타났으며, 이 회귀모형을 유의하였고, 설명되는 변량은 36.9%로 사회적 지지가 포함되지 않았을 때보다 7.4%가 증가하였다. 또한 단계적 회귀분석을 하였을 때, 사회적 지지가 설명하는 변량은 22%로 비교적 높았고, 주관적 건강수준으로 설명변량이 11.4% 증가하였고, 스트레스 인지를 추가하여 우울에 대한 설명변량이 2.7%가 증가한 것으로 나타나, 다른 변수들에 비해 사회적 지지의 설명 변량이 높은 편이었고, 회귀계수도 ${\beta}$=-.319로 비교적 큰 편이었다. 사회적 지지는 본 연구에 포함된 다른 여러 변수에 비해 우울을 가장 잘 설명해주는 요인이므로 사회적 지지 강화 프로그램을 마련하여 우울예방과 관리를 위한 하나의 전략으로 활용할 것을 제안한다.

• 대한임상독성학회지
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• 제14권2호
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• pp.122-128
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• 2016

Purpose: This study was conducted to describe the characteristics of patients with carbon monoxide (CO) poisoning. Methods: We retrospectively surveyed data from the Emergency Department based Injury In-depth Surveillance of 20 hospitals (2011-2014). We included patients whose mechanism of injury was acute CO poisoning caused by inhalation of gases from charcoal or briquettes. We surveyed the annual frequency, gender, age, result of emergency treatment, rate of intensive care unit (ICU) admission, result of admission, association with alcohol, and place of accident. We also surveyed the cause and experience of past suicide attempts by intentional poisoning. Results: A total of 3,405 patients were included (2,015 (59.2%) and 1,390 (40.8%) males and females, respectively) with a mean age of $39.83{\pm}18.51$ year old. The results revealed that the annual frequency of CO poisoning had increased and the frequency of unintentional CO poisoning was higher than that of intentional CO poisoning in January, February and December. The mean age of intentional CO poisoning was younger than that of unintentional CO poisoning ($38.41{\pm}13.03$ vs $40.95{\pm}21.83$) (p<0.001). The rates of discharge against medical advice (DAMA), ICU care and alcohol association for intentional CO poisoning were higher than for unintentional CO poisoning (36.4% vs 14.0%, 17.8% vs 4.7%, 45.2% vs 5.6%) (p<0.001). The most common place of CO poisoning was in one's residence. Conclusion: The annual frequency of total CO poisoning has increased, and unintentional CO poisoning showed seasonal variation. DAMA, ICU care, and alcohol association of intentional CO poisoning were higher than those of unintentional CO poisoning.

• Journal of Preventive Medicine and Public Health
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• 제32권2호
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• pp.228-235
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• 1999

Objectives: Despite the importance of human immunodeficiency virus(HIV) transmission through heterosexual contact, the features of heterosexual transmission has not been well studied in Korea. So we conducted a cross sectional study to determine the transmission rates in married couples and assess risk factors for male to female heterosexual transmission of HIV. Methods: 169 HIV-infected males and their female sex partners were recruited from 1985 to tune 1998. We examined female sex partner's HIV infection status and interviewed male index partners and their female sex partners about demographic characteristics and sexual practices. We analysed heterosexual transmission rate by epidemiologic characteristics, disease status and sexual practices. And we assessed risk factors for HIV infection by univariate and multivariate analysis. Results: 30 female sex partners were infected at enrollment, yielding an transmission rate of 17.8%. Among couples who had used condoms consistently, none of the female sex partners was infected with HIV. In univariate analysis the significant risk factors were full blown AIDS status (OR=4.1, 95% CI: 1.49-11.43) and low CD4 T cell count of index partners at enrollment (OR=7.8, 95% CI: 2.19-27.80). In multivariate analysis HIV-1 RNA levels was significant risk factor when adjusted by CD4 T cell courts and mean sexual contacts per month (OR=19.2, 95% CI: 1.03-357.59) Conclusion: The risk of male to female heterosexual transmission increased with advanced stages of HIV infection in the index male partners.

• Tuberculosis and Respiratory Diseases
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• 제68권3호
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• pp.162-167
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• 2010

Background: To date, there are few data on the risk factors for severe cases and deaths associated with the 2009 pandemic H1N1 influenza A. Here, we describe the clinical and epidemiologic characteristics of patients hospitalized for pneumonia and identify those factors associated with the development of major complications (MC). Methods: We reviewed the medical records of 41 cases of pneumonia admitted to a university-affiliated tertiary hospital between Aug 26 and Dec 10, 2009, and who had confirmed H1N1 influenza A based on real-time reverse transcriptase-polymerase-chain-reaction assay. There were 7,962 patients that fit these criteria. We compared the clinical features and demographic characteristics of patients who developed MC to with those who did not develop MC. Results: During the study period, 10 patients developed MC (required admission to the intensive care unit, n=10; required ventilator therapy, n=6; death, n=4). Patients with MC were significantly older than those without MC and more frequently had underlying medical conditions (90.0% vs 41.9%, p-value <0.01). In the patients with developed MC, the median $PaO_2/FiO_2$ ratio of 230.0 (145.0~347.3) at admission and pneumonia severity index (PSI) score of 141.5 (88.3~158.5) were higher than patients without MC. However, no differences were observed in laboratory findings or in viral shedding between the 2 groups. Conclusion: In hospitalized pneumonia patients of 2009 H1N1 influenza, old age, a history of malignancy, initial hypoxemia, $PaO_2/FiO_2$ ratio, and PSI score appear to be risk factor significantly related to developing MC. These findings might be the basis to influence strategies for admitting patients to an intensive or intermediate care unit and for pre-emptive antiviral therapy.

• 대한임상검사과학회지
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• 제38권1호
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• pp.26-33
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• 2006

Recently, the rapid increase in extended-spectrum ${\beta}$-lactamase (ESBL) producing clinical isolates has become a serious problem. In this study, the epidemiologic features and molecular characteristics of ESBL among clinical isolates of Escherichia coli and Klebsiella pneumoniae, antibiotic susceptibility testing, genotype of the ESBL and patterns of chromosomal DNA from PFGE (pulsed field gel electrophoresis) were observed. A total of 53 ESBL-producing clinical isolates (30 of E. coli and 23 of Klebsiella pneumoniae) were collected from two university hospitals in the period of June to July in 2002 and 2003 respectively. The antibiotic resistance frequency of those 53 strains was tested by the disk agar diffusion method with the result that all the strains were resistant to cephalothin. To other antibiotics, the resistance rates of E. coli (30 isolates) were in order of ceftazidime (90.0%), cefotaxime and aztreonam (respectively 83.3%). Also, the resistance rates of K. pneumoniae (23 isolates) were in order of aztreonam (78.3%), ceftazidime (73.9%) and cefotaxime (65.3%). Also the sensitivity of ceftazidime-clavulanic acid were 100% in E. coli and 95.7% in K. pneumoniae. And the sensitivity of cefotaxime-clavulanic acid was 96.7% in E. coli and 91.3% in K. pneumoniae. The types of the ESBL genes were determined by using polymerase chain reaction (PCR). Among the 30 isolates of ESBL-producing E. coli, 6 (20.0%) have SHV only, 5 (16.7%) have TEM only and, 18 (60.0%) have both of TEM and SHV. Among the 23 isolates of ESBL-producing K. pneumoniae, 7 (30.4%) have SHV only, 2 (8.7%) have TEM only, and 14 (60.9%) have both of TEM and SHV. These results show that 52 strains, with only one exception, were confirmed as either TEM or SHV. The patterns of Xba I-digested chromosomal DNA of ESBL-producing E. coli and K. pneumoniae isolates were analyzed by PFGE. PFGE patterns of E. coli and K. pneumoniae were multiclonal, but many strains were grouped into a few types. Therefore, it seems that there were clonal outbreaks or possible horizontal spread. In conclusion, the TEM and SHV ${\beta}$-lactamase are most widely spread in E. coli and K. pneumoniae in Korea. As these types are usually carried by plasmids, the spread of these ${\beta}$-lactamase genes could compromise the future usefulness of third generation cephalosporins for the treatment of infections caused by E. coli and K. pneumoniae.

• 한국식품영양과학회지
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• 제42권5호
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• pp.705-712
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• 2013

본 연구에서는 제4기 국민건강영양조사 중 성인 남녀를 대상으로 외식 현황과 이와 관련된 인구사회학적 특성, 영양섭취 수준, 식습관 등을 분석하였다. 본 연구의 결과를 요약하면 첫째, 남성이 여성과 비교하여 외식을 자주하는 경향을 보였고, 도시에 거주하는 젊은 성인일수록, 가구소득 및 교육 수준이 높을수록 더 자주 외식을 하는 것으로 보였다. 둘째, 외식 빈도에 따라 영양 섭취 기준 대비 영양소 섭취비율을 분석한 결과 남녀의 패턴이 유사한 경향을 보였는데, 외식을 자주 하는 사람에게서 대부분의 영양소 섭취가 더 높은 반면 탄수화물 및 조섬유의 섭취는 더 낮은 수준을 보였다. 또한 외식 빈도가 높은 그룹에서 낮은 그룹에 비해 에너지/지방 과잉 섭취자의 비율이 더 높은 경향을 보였다. 셋째, 외식 빈도에 따른 아침 결식률을 분석한 결과, 남녀 모두 외식을 자주 하는 사람일수록 아침결식률이 더 높았고, 특히 이는 여성에게서 두드러졌다. 넷째, 대상자의 한국인 식생활 지침 실천도를 분석한 결과, 나이가 많은 여성일수록 식생활 지침 실천도가 더 높은 것으로 보였고, 남녀 모두 외식을 자주 하는 사람일수록 식생활 지침 실천 점수가 더 낮은 경향을 보였다. 이를 바탕으로 구체적인 문항에 대한 실천도를 비교한 결과, 성별, 연령별로 상이한 식생활 문제점이 파악되었다. 따라서 한국인 식생활 중 외식의 비중이 꾸준히 높아지고 있는 가운데, 성인의 건강한 외식 관련 식생활 문화에 기여하기 위한 공중보건안이 마련되어야 하며, 이러한 영양교육 및 정책 마련 시 본 연구 결과에 근거하여 집단의 특성에 따라 외식 관련 식습관문제점이 차이가 있음을 고려하여야 한다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권8호
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• pp.3279-3283
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• 2015

Background: Colorectal cancer (CRC) is the most common gastrointestinal cancer and the incidence is increasing. CRC is more common with increasing age, but a proportion occurs in young adults, termed young CRC. This study assessed the incidence and the demographic of young CRC in Brunei Darussalam. Materials and Methods: All histologically proven CRC between 1986 and 2014 registered with the Department of Pathology cancer registry were reviewed and data extracted for analyses. Young CRC was defined as cancer in patients aged less than 45 years. The various population groups were categorized into locals (Malays, Chinese and Indigenous) and expatriates. Results: Over the study period, there were 1,126 histologically proven CRC (mean age $59.1{\pm}14.7$ years, Male 58.0%, Locals 91.8% and 8.2% expatriates). Young CRC accounted for 15.1% with the proportion declining over the years, from 29% (1986-1990) to 13.2% (2011-2014). The proportion of young CRC was highest among the indigenous (30.8%), followed by the expatriates (29.3%), Malays (14.3%) and lowest among the Chinese (10.8%). The mean age of young CRC was $35.9{\pm}6.2$; lowest among the indigenous ($33.5{\pm}6.7$), expatriate ($34.9{\pm}6.0$) groupd and the Malays ($35.6{\pm}6.5$) compared to the Chinese ($38.6{\pm}4.6$), a similar trend being observed in the non-young CRC groups. There were no difference between the genders and tumor locations (rectum or colon) between the young and the non-young CRC cases. Female young CRC was significantly younger than male (p<0.05) without any significant variation between the various population groups (p>0.05). Conclusions: Our study showed that the young CRC accounted for 15.1% of all CRC with declining trend observed over recent years. Young CRC was more common among indigenous, expatriates and Malays and least common among the Chinese. There were no differences in the gender and tumor locations.

• 대한통합의학회지
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• 제9권4호
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• pp.261-270
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• 2021

Purpose : The purpose of this study is to investigate the effects of sleep duration on stress and depression in college students. The results obtained will be used as a foundational framework for fostering a healthy sleep culture among college students and for formulating measures to improve the quality of their sleep. Ultimately, we intend to produce a publicity and educational material. Methods : For this study, a survey involving 100 college students was conducted, after which data based on a final total of 95 respondents were analyzed. The information on stress and depression were first analyzed in terms of general characteristics and then organized based on the data collected to investigate the effects of sleep duration on stress and depression. The participants were divided into the following groups: "less than 6 hours," "6 to 7 hours," and "7 to 8 hours." BEPSI-K (Brief encounter psychosocial instrument-Korean) was used for stress evaluation, while K-CESD-R (Korean version of center for epidemiologic studies depression scale-revised) was utilized for depression evaluation. Results : First, according to sleep duration, the BEPSI-K scores showed a statistically significant difference in each group (p<.01). In the post-hoc test, there was a difference among the "less than 6 hours" group, the "7 to 8 hours" group. A statistically significant difference was noted (p<.01). In addition, sleep duration had a statistically significant effect on the negative (-) direction of the BEPSI-K (p<.01). Second, the K-CESD-R score according to sleep duration showed a statistically significant difference in each group (p<.01). Notably, in the post-hoc test, the "less than 6 hours" group differed from the "6 to 7 hours" group, "7 to 8 hours" group. A statistically significant difference was noted (p<.01). In addition, sleep duration had a statistically significant effect on the negative (-) direction of the K-CESD-R (p<.01). Third, for the correlation between sleep duration and stress and depression, a negative (-) correlation was found between sleep duration and BEPSI-K and K-CESD-R. Meanwhile, a positive (+) correlation was found between BEPSI-K and K-CESD-R. Conclusion : Based on the findings of this study, the sleep duration of college students has an effect on stress and depression. The results of this study can be used as a foundational framework in formulating a plan for improving the quality of sleep of college students.

• Asian Pacific Journal of Cancer Prevention
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• 제17권5호
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• pp.2401-2405
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• 2016

Background: Both colorectal cancer (CRC) and diverticular disease (DD) are common in the affluent West, and their prevalence is also increasing in the rest of the world with economic development. Both diseases have common epidemiologic characteristics; increasing incidence, more common with advancing age and related to specific dietary changes. However, studies of associations between the two have generated mixed results with some showing positive correlations, whilst others have shown no or negative links. Most of these studies have been from the West with study populations that were predominantly Caucasians. Here the focus was on DD and colorectal neoplasms, including CRC, in Brunei. Materials and Methods: All patients who had undergone complete colonoscopy between 2011 and 2014 were identified and retrospectively reviewed. Patients under the age of 18 years old or had previous colonic surgeries (including previous CRC resection) were excluded. Results: The total number of colonoscopies included in the study was 2,766 (mean age $53.2{\pm}14.8$ years old, male 51.8%), of which DD, CRC and colonic polyps were detected in 17.3%, 4.7% and 28.2% respectively. The proportions of DD, polyps and CRC increased proportionally with age (<30 years, 30-49, 50-69 and ${\geq}70$). Overall, there was no association between the presence of DD and CRC (3.6% vs. 5.0%, p=0.179) but there was a significant association between CRC and left sided DD (p=0.034 by trend). There were also a significant association between presence of DD and polyps (36.1% vs. 28.2%, p=0.001), in particular with right-sided and pan-DD (p=0.001 for trend). Conclusions: Our study showed that the prevalence of DD, CRC and polyps increases with age. There were significant associations between presence of left-sided DD with CRC and right-sided or pan-DD with colonic polyps. This suggests shared risk factors. Further studies are required to assess links in other countries of the Asian Pacific region.